Pteropus alecto (black flying fox): 102898319
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Entry
102898319 CDS
T02993
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
pale
Pteropus alecto (black flying fox)
Pathway
pale00562
Inositol phosphate metabolism
pale01100
Metabolic pathways
pale04014
Ras signaling pathway
pale04015
Rap1 signaling pathway
pale04020
Calcium signaling pathway
pale04024
cAMP signaling pathway
pale04070
Phosphatidylinositol signaling system
pale04919
Thyroid hormone signaling pathway
pale04933
AGE-RAGE signaling pathway in diabetic complications
pale05205
Proteoglycans in cancer
Module
pale_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
pale00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
102898319 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
102898319 (PLCE1)
04015 Rap1 signaling pathway
102898319 (PLCE1)
04020 Calcium signaling pathway
102898319 (PLCE1)
04070 Phosphatidylinositol signaling system
102898319 (PLCE1)
04024 cAMP signaling pathway
102898319 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
102898319 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
102898319 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
102898319 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pale04131
]
102898319 (PLCE1)
Enzymes [BR:
pale01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
102898319 (PLCE1)
Membrane trafficking [BR:
pale04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
102898319 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
102898319 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
102898319
NCBI-ProteinID:
XP_024898013
LinkDB
All DBs
Position
Unknown
AA seq
2302 aa
AA seq
DB search
MTSEEMAASVLIPVTQRKVVSSQSAVDESSDKVLDVSVPKTHTVRQSGSIPSYTISKPNK
LKEESSGSNLPKILSIAREKIMGDENSDEKCWEKNTPDSVENLNINCNNILENHQHGLPQ
SQFYETCDSVTEEGLCLETGIPSSLERKVFPGIQLEMNRPPMGIRASGNQSATIEPSKAH
PDGNMAVFHFHYELDRRMSDTFCTLSDNLILGDCGNCVSLPDVCEEQKKNYMAYTCKLME
LAENCDNENGQLQCDHYDTVNDKYLCREGSCQKASVVCSSDSFCREDFTDSPSAKDFLSH
FEDLPDNCEDVEDFFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIMRTLPSGHIGLAA
WSYIDQKRSGLLLPCGAATGWLSTVVTGQDGSQCLLEAQWYPIYNAVRRGEETEDTIGSL
LHFFTKLPASETAHERITIGPCLKQCVLNNVCEYRATLQRTSVSQYITGSLLEATTSLGA
RSGLLNTFGGSTGRMMLKERQPGTSMANSSALPSSSAGISKELIDLQPLIQFPEEVASIL
MEQEQNIYRRVLPVDYLCFLTRNLGTPECQASLPCLKASISASVLTSQNGEHNALEDLVM
RFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNTVMEFLAGLRSRKVLKM
WQFMDQCDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDG
TSSLLKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKEITVNSIFQIIRSCSR
SLETEEEDSPSEGNSSRKNSLKDKARWQFIIGDLLDSENDIFEQPKEWDPHGLEEPQKAF
DHGTELIPWYVLSIRADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWIKPTTA
SPASAKAKLGVLSNTSEPGKFPLLCNAGLSGLAEGVLDLFSAKAVYMGHPSIDIHTVCVQ
NKLSSMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQR
QQWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGISAKSAEKPSMQRNNTL
GISTTKKKKKILMRGESGEATDDEMATRKAKMHRECRSRSGSDPQDANEQEESEANAIPS
LPNSLPSRRAHSLTTAVSPNLASGTSSPIRPVSSPVLSSNKSPSSAWSSSSWHGRIKGGM
KGFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDLYAVPCNRAGSESAPLYTNLTI
DENTSGLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLG
VFGVGILQLNDFLVNCQGEHCTYDETLSIIQKFEPSISMCHQGLMSFEGFARFLMDKDNF
ASKNDESQENVRELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDC
WDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEI
FKTVFGEKLVTKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLA
SMQAQAYNGGNANLPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYN
EEIPKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGL
STLNASGSSRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSCEGMRQAWEESSSPLS
PTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPN
PLMFWLHGIQLVALNYQTEDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLE
RDLDNMEPAIYSLTIVSGQNVCPSNSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMW
NEQFLFRVHFEDLIFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISS
LFINSRRMEENSSSSTMPASLMFNTEERKCLQTHRVTVHGVPGPEPFTVFSISGGTKAKQ
LLQQILTTEQDIKLIATDYFLMEEKYFISKEKNECRKQPFQRVIGPEEEILQILSSWFPE
EGYVGRIVLKTQKENLEEKSIVQDDKEVILSTEEESFFVQVHDVSPEQPRTVIKAPRVST
AQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTSNKKSSTPKSSQRVLLDQECVFQ
AQSKWKGAGKFILKLKEQVQASREDKRKGISFASELKKLTKSTKQSRGLTSPSQVLASES
VQNKEEKPVGGLSSSDTLDYRQ
NT seq
6909 nt
NT seq
+upstream
nt +downstream
nt
atgacatctgaagaaatggcagcttctgttctcatacctgtgactcagagaaaagtggtg
tcttctcagtcagctgtagatgaaagtagtgacaaggtcctggatgtcagtgtcccaaag
acacatactgttagacagagtgggtctataccatcttataccatctcaaaaccaaacaaa
cttaaagaagaatcttctggaagcaacttgcccaagattctctcaattgcaagggagaaa
ataatgggtgatgaaaacagtgatgaaaagtgctgggagaaaaacacaccagattctgtg
gaaaaccttaacattaactgcaataacatattggaaaaccatcagcatggccttcctcag
agccagttttatgaaacatgtgattctgtcacagaggaaggcctctgtttggaaactgga
atcccttcttcactggaaagaaaggtgttccctggaattcagctggaaatgaatagacct
cccatgggcattagagcctcaggaaatcagtcggcaaccatagagcccagcaaggctcac
cccgatggcaacatggcggtatttcattttcattatgaacttgacagaagaatgtcagac
actttctgtaccctatcagataacttgattttgggtgattgtggaaactgtgtatcgctg
cctgatgtttgtgaggagcaaaagaaaaattatatggcatatacttgtaagctgatggaa
ttggcagaaaactgtgacaatgagaatggccagctgcagtgcgatcattatgacaccgtg
aatgacaaatacttgtgccgcgaaggttcctgccaaaaggccagcgtggtatgttcaagt
gacagcttttgcagggaggattttactgatagtccgtctgccaaggactttctgagccat
tttgaagacctccctgataactgtgaagatgtagaggacttctttaaaagtaaaaaggag
cggtccactttgttagtgaggagattttgtaaaaatgacagggaagttaagaagtctgtg
tatacagggacaagggcaattatgaggactctgccttctggtcacattggtctggcagct
tggagttacattgatcagaaaagaagtggtctcttattgccttgtggggcagcaacggga
tggctatcaacagtggtgactgggcaagatgggagccaatgtctattagaagcccagtgg
tatccgatctacaatgcagtgagaaggggagaagaaacagaagatacaattggatctctt
ctccatttcttcacaaagctcccagcctccgagacagcccatgaaaggattaccattggt
ccctgcttaaagcaatgtgtcctaaacaacgtttgtgaatatcgtgccaccctccaaagg
acttctgtatctcagtacatcaccggttctctcctagaagcaaccacatctttaggagca
aggagtggccttctcaatactttcggaggatctactggacgaatgatgctgaaagaacgc
caaccaggcacctctatggccaattccagtgccctcccttcaagttcagctgggatcagc
aaggaactgattgatctgcagcccctcatccagttcccagaggaagtcgccagcatcctg
atggagcaggaacagaatatttaccgaagggtcttgccagttgactatctttgcttcctg
actcggaacttgggcactccagaatgccaggcttcactgccctgcctcaaagcatccatc
tcagcatcagttctcacctcccagaatggagagcacaacgcccttgaagatcttgtgatg
agatttaatgaggtgagctcctgggtaacgtggctgatcctcacggcgggttccatggaa
gagaagcgggaagtcttctcgtatttggtgcatgtggccaaatgctgctggaatatggga
aactacaacaccgtcatggagttcttggccggcctcaggtcaagaaaagttttgaagatg
tggcagtttatggaccagtgcgacctggagaccatgcggagcctgaaggatgccatggct
cagcatgagtcatcctgtgagtacaggaaggtggtgacgcgggctctgcacatccctggc
tgcaaggtggttccattctgcggagtgttcctgaaggagctctgtgaagttcttgacgga
acctccagcctcctgaagctttgcccgaggtacaattcccaagaagaaactctagagttt
gtagccgactacagtggacaagataatttcttacaacgagtgggacaaaatggcttaaag
aattcagagaaggagatcacggtcaatagcatctttcagatcatcaggagctgcagtcga
agtctggagacagaggaagaggacagccccagtgaagggaacagctctaggaaaaactcc
ttgaaggataaagctcgatggcagtttataattggagatttgttggattctgaaaatgac
atttttgagcagccgaaagaatgggatcctcacggattagaagaaccgcagaaggccttt
gaccatgggacagagctcatcccgtggtatgtcctgtccatccgagctgatgtgcaccag
tttctactgcagggagccacggttatccactatgaccaggacacacacctctctgcccgc
tgcttcctccagcttcagcctgacaatagcaccttgacctggataaagcccaccactgcc
tccccagccagtgctaaagcaaaacttggtgtgcttagtaacacatccgagcctggtaaa
ttcccgttactgtgcaatgctggattaagtggcctggcagagggagtcttggatctgttt
tcagcaaaggctgtgtacatgggacaccctagcattgatatacacactgtgtgtgttcag
aacaaactgagtagcatgttcctctcagagactggtgtgacactgctctatgggcttcag
accacggacaatagattattgcattttgtggcaccaaagcacacagctaaaatgctcttc
agcggattattggaactcactagagctgtgagaaagatgaggaagttccctgaccaaagg
cagcagtggctacggaaacaatacgtcagcctctatcaggaggatggacggtatgaaggc
ccaactttggctcatgctgtggagttgtttggtggcagacgatggagtactcgaaacccc
agccctgggatatcagcaaagagtgccgagaagcccagcatgcagaggaacaacaccttg
ggcataagcaccaccaagaaaaagaagaaaatccttatgaggggagagagtggggaggca
accgacgacgagatggccacccgaaaggccaaaatgcacagagaatgtcggagccggagt
ggctctgatcctcaggatgctaacgaacaagaagaatcagaggcaaatgccatcccaagc
ctgcctaactctctcccttccagaagagcccactccctgaccacagctgtgtcccctaac
ttggcttccgggacatcatctcccatcaggccagtgtcctcccctgtgctgtcttcaaac
aagagcccgtccagtgcttggagcagcagcagctggcatgggcggatcaaaggaggaatg
aaaggctttcagagtttcatggtttcagacagtaacatgagttttgttgaatttgttgag
ctgttcaaatcattcagtgtaaggagcagaaaggacctcaaggatctctttgacctctat
gccgtgccctgcaaccgagcgggctctgagtcggccccactctacaccaatctaaccatt
gatgaaaacaccagtggtcttcagcctgacctagatttgttgaccagaaatgtctcggat
ttggggttgttcattaaaagtaaacagcaactgtcagacaaccagaggcagatctctgat
gccattgctgctgcaagtatcgtgacgaatggtactggggtcgagagcacatctctgggt
gtatttggggttggaatactccagctcaatgactttctagtgaattgccaaggagaacac
tgtacttacgatgaaaccctcagcatcatccagaagtttgagcccagcattagtatgtgt
catcaaggcctaatgtcatttgaaggatttgcaaggtttctgatggataaagataacttt
gcctcgaaaaatgatgaatcacaggagaacgttagagaattgcagctgcccctctcctac
tattacattgaatcttcacacaatacctacctcacaggccatcagctcaaaggcgaatcc
tcagtagaactctacagccaggttctcttgcaaggctgcaggagcgtagagttggactgc
tgggatggagatgatgggatgcccatcatttaccatggacacacactgacaaccaagatc
cccttcaaggaagtggttgaagccattgatcgcagtgccttcatcaactctgacctgcca
atcatcatatcaattgagaaccactgttcattgcctcagcaacgaaaaatggccgaaatt
tttaagactgtgtttggagaaaaactggtgactaaattcttatttgagagtgacttctca
gatgatccaatgcttccctcacctgaccaacttagaaggaaagtgcttcttaaaaataag
aagctaaaggcccatcagacgccggtggatatcttaaagcaaaaggctcatcagttagca
tccatgcaagctcaggcttataatggtgggaatgccaacctcccacctgctaataacgag
gaggaggaagatgaagaagatgaatatgattatgactacgaatccctctctgatgacaac
attctagaagacagacctgaaaataaatcatgtaatgacaagcttcaatttgaatataat
gaagaaatccccaagaggataaagaaagcagataactctgcttgcaacaaaggaaaggtt
tacgacatggaactgggagaagaattttatcttccccagaataaaaaggaaagcagacag
attgcaccagagctttctgaccttgttatctattgccaagcagtaaaatttccaggcctg
tcaactctaaatgcatctggctctagcagaggaaaagaaaggaaaagcaggaagtccatt
tttggcaacaatccgggcagaatgagccctggggagacagcatcattcaacaaaacatct
ggaaaaagttcctgcgaaggaatgcgacaggcctgggaggaatcttcttccccactcagc
ccaaccacatccctcagcgctatcattagaactcccaaatgctaccatatctcatcgctg
aatgaaaatgccgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcacacc
gcctgtcagctgctgaggacctacccagctgccacccgtatcgactcgtccaaccctaac
cccctcatgttctggctgcatgggatacagctcgtggcactcaactaccaaacagaggat
ctccctttacatttaaatgctgccatgttcgaggccaatggtggctgtggttatgtttta
aaacctccagttctgtgggacaagaattgtcccatgtatcagaagttttctcccttggaa
agagacctggacaacatggagcctgccatctattctttaactattgtctctggacaaaat
gtgtgcccaagtaacagcacaggaagcccgtgtattgaagttgacgtcctgggaatgccc
ctggacagctgccattttcgcacgaagcccatccatcgaaataccctcaaccccatgtgg
aacgaacagtttctcttccgagttcattttgaagatctcatatttcttcgttttgcagtt
gtggaaaacaacagctcggcagtaactgctcagagaatcattccactcaaggctttaaag
cgaggatatcgacatcttcagctgcgaaacctccacaatgaagtcttggaaatctccagt
ttattcataaacagcagaaggatggaagaaaattcctctagcagtaccatgccagcctct
ttgatgtttaatacagaagaaagaaaatgtttgcagactcacagagtcacagttcatggg
gtcccaggtccagagccctttactgttttctctataagtggaggcaccaaggcaaagcag
cttctccaacaaattctgaccaccgaacaagacatcaaacttattgccacagactacttt
ttgatggaagaaaaatattttatatctaaagaaaagaatgaatgcagaaaacaaccattc
cagagagtcattggtccagaagaagagatcttgcagattttaagcagctggtttccagaa
gagggatacgttggcagaattgtcttaaaaacccagaaggaaaacctagaagagaaaagc
atcgtgcaagatgacaaggaggtgatcttgagcacagaggaggagagtttctttgtccaa
gtgcatgatgtttctccagagcaaccgcgaacagtcatcaaagcaccccgcgtcagcacc
gcacaggatgtcattcagcagaccttatgcaaagccaaatactcctatagcatcctgagc
aaccccaacccgagtgactatgtgcttttggaagaggtggtgaaagacacttccaacaag
aagtcttctaccccaaagtcctcccagcgggtcctcttggatcaggagtgtgtgtttcaa
gcacaaagcaagtggaaaggtgcaggaaaattcatcttgaagctaaaggagcaggtgcag
gcatcccgagaagacaaaagaaaaggcatttcttttgcaagtgaactcaagaagctcacc
aagtcaactaaacagtcccgaggactcacatcaccttctcaggtcttggcctcagagagt
gtccaaaacaaggaggaaaaacctgtgggaggcttgtcctccagtgacacgctagactac
cgacagtga
DBGET
integrated database retrieval system
