KEGG   Periplaneta americana (American cockroach): 138696096
Entry
138696096         CDS       T10946                                 
Symbol
LRP1
Name
(RefSeq) low-density lipoprotein receptor-related protein 1 isoform X1
  KO
K04550  low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor)
Organism
pame  Periplaneta americana (American cockroach)
Pathway
pame04148  Efferocytosis
Brite
KEGG Orthology (KO) [BR:pame00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    138696096 (LRP1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pame04131]
    138696096 (LRP1)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:pame04090]
    138696096 (LRP1)
Membrane trafficking [BR:pame04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Low-density lipoprotein receptor (LDLR) family proteins
    138696096 (LRP1)
CD molecules [BR:pame04090]
 Proteins
  138696096 (LRP1)
SSDB
Motif
Pfam: Ldl_recept_a Ldl_recept_b FXa_inhibition DUF5050 SGL Vgb_lyase cEGF EGF_2 EGF
Other DBs
NCBI-GeneID: 138696096
NCBI-ProteinID: XP_069676734
LinkDB
Position
3:63731925..64155653
AA seq 4709 aa
MRLNFELLYFVLAALCFTTLDGHEVEETVSSELCAQDQFRCENGNCIPLRWKCDASPDCD
DGSDEPPDCIPSPCKLGQFQCSLTHKCIPRGWICDGESDCGVSKGIFADMSDEDPQLCQK
SVSCPPNQFRCEDSVQCLPVTLLCDGALDCPDESDEGEFCHNVTLCESMQCAHGCRPSLS
GPLCFCPEGQQPNKSLCVDSDECLIDGSCDQLCTNKNGSFDCRCVPGYEKNGTSCTAINV
PSDEPASIVFSSTADIRRIHLNGSSYPGNSSLTPLQTLALEFNHRNRSLCFILHNSSNAR
LSCANIDNLSDSWDLPTPTMFPLDSMTHIALDWISGNWYFLDDTREMIFLCNSTMQACVI
LVGVNLSKPRGIALDPTKGFMFFTKWGASSPMLERTLLDGSNRTTLVQQKIVYPYGVTVD
YPTQQVYWVDTYLDFVERIDYDGSNRRTIKKGFPVQNLYDVTVFENSLYVTSWRNQSIIR
LDKFNSDDHETVANLSRPFAIHIFHRQRQPEESHPCGVNNGGCQHICIPAWKKGRGVAQC
LCKAGYRSVRNGQCMVAKQSQFLLFGKARPAMIKAIALTGKQRPQEVMIPVMDLSRPAAL
DYDVKSQYIYYSDVQRYVIERQKIDGSNRSVVLNKGINNCEGLAIDWMGRNIYWTDQGLG
AIGVARLDDTTQWKHFLYPNMYHPRAIVVHPKMGLMYWTDWASSASQRGKIEQAWMDGTH
RISLIESQLQWPNGLSIDYVDKKLYWCDAFLDKIERASLDGSNREIVYNGPQLDHPYGLA
YFDHSIYWTEFQKGTVHRKSLNSDDNSTETLSEEFSSLFEIRVFDNTSQTGSNACTNDNN
NCPELCLAVPNGTVCVCRDGHILDGTACVVQSNYTAPSRCTYRNFQCRDNLRCIDTRYVC
DGDDDCGDGSDEDTGPGGICENVHCRDDQFRCDSNRCITRYWVCDGDKDCSDGSDEDPKE
CQNTTCSPTQFTCAVSKRCIPLTWMCDSDPDCGDGDTSDEPSNCEYPECLPTEFVCDNKH
CVPYDYFCDGDDDCRDGSDEKFCHGFCDAATQIFCQMDATCLPLSDRCNGHVDCSDGSDE
AKCNKTRPGKMCKADEFRCTDGSSCIKKGLVCNKHKNCNDGSDEKYCEHMCEAHEFRCGD
GACIRTKFVCDGHEDCVDGLDEADCNGTIHEIEMITPSPESTEAPSQCHHPSQLCDNKTV
CMSVDRLCDGKADCEDGSDEGLRCGERVCDRSSDCSHHCHDAPTGRICYCPPHLHLQPDQ
MTCLASHPCEAWGVCSQLCEPLKYGHKCTCEHGYKLQHDGFTCKSTENATAYVIFSNRHE
LRGVDLQTFSVKALISSLKNTIALDFYYKEDSKTVSIYWTDVIDDKIYRGTLVGSSLSNI
EVVVQTGLATAEGLAVDWIGQNLYWVESNLDQIEVARLNGSFRRTLIAGDMESPRAIALD
PRYGLLFWTDWDANAPRIERCSMSGQNRTVVVRVDQVTDGAWPNGLTLDYMLKRIYWIDA
RSDSIHTTFYNGSDHREVIRGHEMLSHPFAIALFGNYVYWTDWRTNAVIRANKWNGSDIS
VIQRTLTQPFDIQILHPSRQPRDVKNPCGDNNGNCSHLCLLSVNGTFKCDCPHVMRLNKD
QRTCVAVNERVLLFSRANEIRGVDLGMPYYHTIPTISLPQVLSPSQLDFVAATHKIYWTD
IQVNEVKRTGLTGGITESIIDTGIEQPTGFAIDWISGNMFVSSSRSTSSNILVCSLEGEM
VATVVEDANFQIRSLALDPLRGKLYWSSWSGDNYMIHQAHMDGSEQIVLVSRREDDALHS
PQSLCMDLESQRLYWVNTGSDSVQYYDFLTSLVVTVHLNNDHPTAATVYRGKLYYANQDD
NAIHVTNKTTGADNTILRNNTASVTSLRIYDPEVQTGDNACSVNKGNCSHLCLPISETER
MCMCATGYVTDSSDSTKCVGIDEFLFYSINWEIKGLPLGDDNTTQMLGPISRVSMASSID
FHAKLDYLYWADSDHGTVTRIRRDGTGRQTVVEHFESMESIPVDWLPGLAVDWVAGNVYW
TDPKFNVIEMARLNGSCRYVVVTGNLDKPTAIAVDPPNGFLFWSDAGKEPRLERSRLDGS
QRFVLVNDTGNSINDIALDYENQKLYWCDSRTNRIERINYDGSDREVLLEQTLDSPRAIT
VHQDRVFWIDIAYERGSILSAPASNLSDHRILLSGAGDALKDIQVFTTARQQGTNPCAID
NGGCAELCLYNGTHPVCACAHGKVTEKGTCENYDSFLVYSRVVRIDSINMFDELNRNAPY
PSIQSKDFMRNAIGLTFDYERSKIFYSDIQRGSINSVFFNGTGHKPIVERQGSVEGLAYE
AINNMLYWTCNNDATINRINLTNNESKVEQIITLGANDKPRGIDVDSCNMRIYWTNWNSH
NPAIQRAYVTGYDKENIITTDIRMPNALTLDHKAQKLYWGDARLDKIERAEYDGSNRVIL
AKVTPQHPFDLAVYGDFIFWTDWVLHAVIRANKYTGEDVVWLRKEVPRPMGIIAIANDTN
DCMTNPCRVLNGGCQDECTLLASGAVQCRCFPGRTLLGDGQRCTSKDADCNEQEFRCSAG
GCIPYHLTCDGVANCEDESDEDPHYCALRMCPPGFFQCQNNRCMPNNRVCNHMNDCGDLS
DEANCSCSSEHNFRCATGQCILASFRCDNDPDCPDASDEMHCEKPRNCSELQPSLPVIAC
NHTTSCIHVNWICDGENDCWDNSDEENCDHHTTTTAPQECSSLQFQCANGHCIMKAWLCD
KDNDCDDAVGDGPSSDEQNCTYHCRPDQFKCNNSDCIPTTWRCDGTPDCSDSSDETEDCK
TRVCPHTDFLCNSTGRCIPSTWTCDGEEDCSDGSDESVEVGCLHVNNTHCPPNQFRCANH
RCIDMEYYCDRDDDCGDGSDEPLYCNKKCHTNEMACKNGRCILAQWRCNGKDDCGDHSDE
DDCHHQGCQGADMFKCNNNLCVNETLLCNGENDCGDYSDEELCNINECENQNLCAHICTD
KKIGYECSCHSGSRVHPKDPHLCSDVDECQDRPCSQTCRNLLGSYVCSCVEGYILRADKH
SCKANSNIEPKLIFTNRYYIRELDLNGKNTLRAHNLANAVALDYDWAEQCIYWSDVMALG
SSIKRLCGSSDSAYQVLHSATLQNPDGLAVDWVGRNLYWCDKGLDTIEVSKLDGRYRKVL
INTGLQEPRAITLDPRNGYMYWTDWGDRPYIGKAGMDGSGQRILVNDSLGWPNALTISYE
TNELFWADAREDYIAVSDLEGNNRKIILSRERDSKVMLHHIFALTVLEDYLYWTDWETKS
VERCHKYNGTDCSTLTTTVHRPMDIHAYHPLRQVPVSNNPCLHNAGCSTLCLLSPNHGHQ
CACPENYILDEDGRSCIANCTTAHYICATTYKCIPFWWKCDTQDDCGDGSDEHKDCPKFE
CMPGQFQCNNTNCIHPSQLCNGESECGDGSDEMDCNQYTCLGTQFKCKGNASVSDRCIPL
SKQCDGHADCLAEEDEQDCPPKTCPPNQYSCKNKKCIPSVWECDGDNDCGDNSDENQNCK
ERKCPIDHFKCQSGRCIPKSWQCDGDHDCSQGEDEPASCSSADFHTCDPTYFKCKNNKCI
PGRWRCDYDNDCGDHSDEDGCVPRKCSESEFRCSDGRCIRGIHHCDGEYNCDDHSDENNC
NTTCNQNEFQCQNPHYCIFIEWKCDGDTDCSDGSDEANCNDSCPDNQFTCQNKQCISISW
RCDGDDDCGDNSDEMQCESLACPPGRHRCKNHICISPINVCDGKDNCGDGSDEDPVVCQQ
SGHCTLDQFRCANKNCISKKLQCDSFNDCGDNSDEEGCIQPPCHFGACSQICVEKKGGNF
ACHCAPGFIGEGTSRNKTCLAKGKPAHLMVAGETDLRDLNPYKAGENSPTQTLSKQFSDP
GHKVESMDILWDPAKSAVFWSDHHSKMIRRSYLYDMPSTRTRPRRVQRDDMKVLAMNLVD
PRGLAVDWVGRRVYWVDAGQDVVMVSDLTGEKKSTLIDTELDQPHDIVVDPQSGLMFWSD
WGVNSRIESAYMDGTGRRALVNTMVQWPTGLAIDYPARRLYWTDPKAYTVESVDLNGQDR
QLIKRFPHREKPYKVEVFEDSLYVSTYQTNNIIKLNKFGHGNLTYLVQGLNRASDILIVQ
ENKQTKNLKNPCHPSPCHNSTLCLLGPSSHTEPSFSCVCPDGLVKTVGSDNKSSSAQVVC
IPTVRTPKVCDLDCHKGTCQMVKDKPVCRCQPLYDGDRCQNFRCSQYCRNKGLCFADLLT
PVPSNLPPPLKCNCPAQWTGERCEIPVHMCENRCLNNGTCFSPRPGLAQCNCLPGFTGSR
CENCVNLMCQNGGVCNRTDGLEHCVCQSGYSGTHCEHSDCDQYCLQGTCSLTARGPVCNC
PPSFTGKRCEHDGCVGHCHNGGTCIPGAKTLTCSCPPRFTGRRCEVDLCKCTPCQDLNDP
DCKCPVEQPAECHNSCYPDQCLNGGTCITVNGEPFCKCTGEYGGKDCSLHYGLQNPCQDY
CKQNGICTLTAHGPMCHCLVGWTGSRCEERSACKGYCFNGGTCQESPDPSLKPSCICPST
NTGDRCQSPVLDFSVARGAEGNNYTMVMVVTVALTFLLVLVGSLVLACYMLRRRRSGKPF
MHVRMHENVEISNPMYLREEVDDDADALDGNFSLDADKSGNFANPVYDSLYNVGSTGNGT
TSVSEEKKGLLQRASKEGQHPSTDTRDSL
NT seq 14130 nt   +upstreamnt  +downstreamnt
atgagactgaatttcgaattgttatattttgtgttggcggctttatgtttcactaccctc
gatgggcatgaggtggaggaaaccgtcagttctgagctatgcgctcaggaccagttccgg
tgcgagaatgggaattgcattcccctgcggtggaagtgcgatgcgagtccagactgcgat
gacggctctgacgaacctcccgactgcataccgagtccctgcaagctggggcagttccag
tgcagcctcacgcacaaatgcattccacggggatggatctgcgatggcgagtcagactgt
ggtgtgtccaaaggaatcttcgcagacatgtctgacgaggatcctcagctgtgtcagaaa
agtgtgagctgccctccgaaccaatttcgctgtgaagactctgtccagtgcctgcctgtc
acattgttgtgcgatggggcgcttgactgtcctgacgaatctgacgaaggagaattttgc
cacaatgtgaccctgtgtgagtcaatgcagtgtgcacacggatgccgtcccagtctttca
ggtcccctgtgtttctgtcctgaggggcagcagcccaacaaatctctctgtgttgattct
gatgaatgcctcattgatggatcatgtgatcaactgtgcacaaacaagaatggctccttt
gattgccgctgtgtccctggctatgagaagaatggcacgagttgcactgcgatcaatgtt
ccatccgatgagcctgccagcattgtattcagtagtacagcagatattcgtcgtattcac
ctgaatggttcatcatacccaggcaatagttctctgactcccttgcagaccttggctctg
gagttcaaccacaggaatcgcagcctttgtttcatcctccacaactccagcaatgccaga
cttagttgtgccaacattgacaacctcagtgactcatgggatctcccaaccccaacaatg
tttccactggactcaatgacacacatcgcgttggactggatctctgggaactggtatttt
cttgatgacacccgagaaatgatcttcttgtgcaactcaacaatgcaagcatgtgtcatc
ctggtaggcgtgaacctcagcaagccccgggggatagcactagatccaacaaaagggttc
atgttctttaccaaatggggagcatcaagcccaatgctggaacgcacactactggatggt
tcaaatcgaacaactctggtgcagcagaagattgtgtacccatatggtgtgacagtcgac
tatcccacacagcaagtgtactgggtggacacatacctagacttcgtggagaggattgac
tatgatggttccaacagacgtacaatcaagaaggggtttccggtgcagaacttgtacgat
gtcactgtctttgagaatagcctctatgtgacaagctggcgcaatcagagcattattcga
ctggacaagttcaactctgatgaccatgagacagtggccaatctgagtcgaccatttgct
attcatatttttcatagacaacgtcaaccagaagaatcacacccatgtggagttaacaat
ggaggctgccagcacatttgcattcctgcatggaagaaaggtcgtggtgtggcacagtgc
ctgtgcaaggcaggttaccgatctgtacgcaacggtcagtgcatggtggccaagcagtct
cagttcttactgttcgggaaggctcggcctgctatgataaaagctattgcactcactggg
aaacaacgaccgcaggaggtgatgatccctgtcatggacttgtcgagaccagctgcactg
gactatgacgtcaaatcgcaatacatatattactctgacgtacaaagatatgttattgaa
cgacagaagattgatgggtcaaatcgttcagtagttcttaataaaggcatcaacaactgc
gaaggtttggctattgactggatgggtcgcaatatttactggacagatcaaggcctgggt
gcgattggagtggcccggctagatgacaccacccagtggaagcacttcttgtaccccaac
atgtaccatcccagagccattgtcgtccatcccaagatgggcctcatgtactggacggac
tgggcgagctcagcatcacagaggggcaagatagagcaggcctggatggacggaacccac
cgcatttctctgatagagtctcagctgcagtggcccaatggactcagcattgactatgtg
gacaagaagctgtactggtgtgatgccttcttggacaagatagaacgtgctagtttggac
gggtcaaatagggagattgtgtacaatggaccacaattggaccatccatatggactggct
tatttcgatcattctatctactggactgaattccagaaaggaactgttcatcgcaaaagt
ctcaattcagacgacaattcaactgaaacattgagcgaagaattttcatccctttttgaa
atccgcgtgtttgacaacacttctcagacaggttcaaatgcttgcacaaatgacaacaac
aactgcccagagctgtgcctggctgttcccaatggcacagtttgtgtatgtcgtgatgga
cacattctggatggaacggcatgtgtagtgcagtccaactatacagcaccttcacgatgc
acatatagaaacttccagtgccgtgacaacctgcgctgcatagatacacgttacgtgtgt
gatggtgatgatgactgtggtgatggttctgatgaagacactggtcctggaggcatatgt
gagaatgtgcactgccgagatgatcagttccgttgtgacagcaaccgctgcattacacgg
tactgggtgtgtgatggtgataaggactgctctgatggctctgatgaggaccccaaagag
tgccagaacaccacgtgcagccccacgcaattcacctgtgcggtgtcgaagaggtgcatt
ccactgacctggatgtgtgactctgatccagactgtggtgatggggacacatcagatgaa
cccagcaactgtgagtacccagagtgtctaccaactgagtttgtgtgcgacaacaagcac
tgtgtgccatacgactacttctgtgacggagatgatgactgtcgtgatggaagtgacgag
aagttctgccatggcttctgtgatgctgcaactcagattttctgtcaaatggatgcaacg
tgtttgccactgtctgatcggtgcaatggtcatgtggactgcagtgatggcagtgatgaa
gccaagtgcaacaaaacaagacctggcaagatgtgcaaagcagacgagttccgctgcact
gatggcagctcctgcatcaaaaaggggctggtctgcaacaagcacaagaactgcaacgat
ggttctgatgaaaagtactgtgagcacatgtgtgaggcccacgaattccgctgtggtgat
ggtgcatgcatcaggacgaagtttgtatgtgacggccatgaagactgtgtggatggtctg
gacgaggcagactgcaatggaacaattcatgaaatcgaaatgatcacaccatctccagaa
tcaacagaagctccttcgcaatgccaccacccatcacagctatgtgacaacaagacagtc
tgtatgtctgttgacagattgtgtgatggcaaggccgattgtgaggacggatctgatgaa
ggacttcgctgtggagaacgtgtttgtgatcgaagtagtgactgcagccatcattgccat
gatgcccccacaggccgcatctgctattgtcccccacatcttcatttgcagcctgaccag
atgacctgtctggcatcacatccctgtgaggcgtggggagtatgttcccaactatgtgag
ccccttaagtatggacacaaatgcacatgtgagcacggctacaagctgcaacatgatggg
ttcacgtgtaagagcacagaaaatgcgacagcatatgttatattctcaaatcgacatgaa
ttgcggggagtggacttgcagacattcagtgtgaaggcactgatctccagcctcaagaac
acaattgctctggacttctattacaaggaagactccaaaactgtgtccatctattggacg
gatgtcattgatgacaagatctatcgtgggactttagtaggaagctccttgagcaacatt
gaagtggtggtgcagacagggctggcaacagctgaaggcttggctgtggattggattgga
cagaatctgtactgggtggagagcaacctggaccagatcgaagttgccaggcttaatggc
agcttcagacgcaccctgatagctggggacatggaatccccccgagcaattgcgctagat
cccagatatgggttgttgttctggacagactgggatgccaatgccccacgtatcgagcgc
tgcagcatgagtggacagaacagaactgtggtggtccgtgtcgaccaggtgacagatgga
gcatggcccaatggtctcactttggactacatgttgaaaagaatatattggattgatgcg
agatcagactcgatccacacaactttttacaatggctctgaccaccgtgaagtgatccgt
ggccatgaaatgctgtcacatccctttgctattgccctgttcggcaattacgtgtactgg
acggactggcgcaccaatgccgtcatcagggccaataagtggaatggctctgatatcagt
gtgattcagcggacactcacacagccatttgacattcagatcttgcatccaagccggcaa
cctagagatgtgaagaacccatgtggtgacaacaatggcaactgttcacacttgtgcctg
ctgagtgtgaatggaaccttcaagtgtgactgtcctcatgtcatgcgcctcaacaaggac
cagcgtacctgcgttgcagtgaacgagcgagtgctattgttctcccgtgctaatgagatc
cggggcgtggatctgggcatgccatactaccataccattcccaccatcagcctgccgcag
gtgctgtccccctcacagctcgacttcgtggctgccacacacaagatctattggacggac
atccaggtgaatgaagtgaagaggacagggctgactggaggcatcactgagagcatcatt
gatacaggtattgagcaacccacaggctttgccattgactggatctcaggcaacatgttt
gtgagctcatctcgttccaccagcagcaacatcttggtatgcagtttagagggcgagatg
gttgccacagtggtggaggatgccaactttcagatccgctctctggcactggacccactg
cgtgggaagctatactggagcagctggagtggagacaactacatgatccatcaggcacac
atggatggcagtgaacagattgtgctggtttcacggcgtgaggatgacgccctgcacagc
ccccagagtttgtgcatggacctggagtcacagcggctgtactgggtcaacacaggcagt
gactcagtgcagtattatgacttcctgaccagcctcgtggtcacggtacatctcaacaat
gaccaccccactgcagcaactgtgtaccgaggcaagctgtactatgccaaccaagatgac
aatgctatccatgtgaccaacaagactactggtgcagacaacaccattcttaggaacaac
actgccagtgtgacttcactgcggatatatgatccagaagttcagactggtgacaatgcc
tgctcggtgaacaagggcaactgctcccatctgtgcctgcccatctcggagactgagcgt
atgtgcatgtgtgcaactggctacgtaactgattccagtgacagcacgaagtgtgttgga
attgatgagttcctgttctactctatcaattgggagataaaaggtttgccacttggagat
gacaacacaacgcagatgctgggaccaatatcccgtgtgtccatggcaagcagtatcgac
tttcatgcaaagttagactacttgtactgggcggacagtgatcatggtacagttacaagg
atccgacgtgatggcactggccggcaaactgtagtggaacactttgaatcgatggagagc
atccctgttgattggctaccaggtctggctgtagattgggtggctggcaacgtatactgg
acagaccccaagttcaacgttatagagatggcacggctgaatggctcctgtcgctatgtg
gtggtgactggaaacctggacaaaccaacagctattgcagtcgaccctccaaatggtttt
cttttctggagtgatgctgggaaagagccccgcttagagagatcaagactggacggttca
cagcggtttgttttagtcaatgacaccgggaactccattaatgacattgcactggactat
gagaaccagaagctgtactggtgcgactcaagaaccaacaggattgagcgaatcaattat
gacggctcagatcgtgaagtgctgttggagcaaactctggacagtccacgtgctatcact
gtgcaccaggatcgtgtgttctggattgacatagcatatgagcgaggcagcattctgtcg
gcacctgcttcaaatctatcagaccacagaatcctcctgtctggagcaggtgatgccctt
aaggacattcaagtgtttactacagctcgtcaacaaggcacaaacccatgtgccatcgac
aatggaggttgtgcagagttgtgtctctacaatggaacacacccagtatgtgcatgcgcc
catggaaaagtcacagaaaaaggaacgtgcgaaaattatgatagttttctggtgtactca
cgtgttgtgagaatagacagcataaacatgtttgacgaacttaaccgcaatgccccgtac
cccagcatccaatccaaggacttcatgaggaatgctattgggctcacatttgattatgag
cgcagtaaaatattctactctgacatacagcgagggagcatcaactctgtcttcttcaat
ggcactggccacaagcccatcgtggaacgacaaggttcggtagaaggtttagcttatgag
gccatcaataatatgctgtattggacatgcaacaatgatgcaactatcaacagaatcaat
cttacaaacaacgaaagcaaagtggagcagataattactttgggtgcgaatgataaacca
cgtgggattgacgtcgacagctgcaatatgcgtatatactggactaactggaactcccac
aacccagccattcagagagcatatgtgactggttatgacaaggagaatataatcacaaca
gacatccggatgccaaatgccttgaccttggatcacaaagcacagaaactgtactggggt
gatgcaaggctggacaagatagagcgagcagagtatgatggttcaaaccgagtgatactg
gccaaagtgaccccacagcatccatttgacctggctgtgtatggtgacttcattttctgg
acggactgggtgctccatgctgtgatccgagccaacaagtatactggtgaagatgtggtg
tggctcaggaaggaagtaccacgaccaatgggcattattgctattgccaatgacaccaat
gactgcatgacgaacccatgtcgtgtgttgaatgggggctgccaggacgagtgcaccctt
ttggcatcaggggcggtgcagtgtcgatgctttcctggacgcacattgttgggtgatggc
cagcgctgcaccagcaaagatgcagactgcaatgagcaggaattccgctgttctgcaggg
ggctgcatcccttaccacttgacctgtgatggtgtcgccaattgtgaggatgaatctgat
gaagacccacactactgcgcactgcgcatgtgtccacctggcttcttccagtgccagaac
aaccgctgtatgccaaacaaccgggtctgcaatcatatgaatgactgtggtgacttgagt
gacgaagccaattgctcatgctcatcagaacacaacttccgctgtgccacaggacagtgc
atacttgcgagcttccgttgtgacaacgaccccgattgccctgatgccagtgatgagatg
cactgcgaaaagcctcgcaactgctcagagctgcagccgtcactccctgtgattgcctgc
aaccatacaacatcctgcatccatgtgaattggatctgcgatggcgagaatgactgttgg
gacaacagtgacgaagagaactgtgaccaccatacaaccacgacagctccccaagagtgt
tcttcactccagttccaatgtgccaatggtcactgcatcatgaaagcctggctctgtgac
aaggacaatgattgtgatgatgcagttggtgatggccccagttctgacgagcagaactgc
acataccactgccgtcctgaccagttcaagtgcaacaactcagactgcatccctaccacc
tggcgttgtgatggcacaccagactgctcagacagctcggatgagacagaggactgcaag
actcgagtatgtcctcacacggatttcctctgcaacagcacagggcgatgtatcccctct
acctggacatgtgatggagaggaggactgcagtgatggctctgacgagtctgtggaagtg
gggtgtctgcatgtcaacaacacacactgtccaccaaatcagttccgctgtgcaaaccac
cgatgcattgatatggagtattattgtgacagagatgacgactgtggggatgggtcagac
gagccactgtactgcaacaagaagtgccacaccaacgagatggcctgtaagaatggacgc
tgcatcctggcccagtggaggtgcaatggcaaggatgactgtggcgatcactcagatgag
gatgactgccatcaccagggctgtcagggtgcagacatgttcaagtgcaacaacaatctg
tgcgtgaatgagaccttgctgtgcaatggggaaaatgactgtggtgactacagtgatgag
gagctttgcaatatcaatgagtgcgagaatcagaacctgtgtgctcacatctgcactgat
aagaagattggctatgagtgctcttgccactctggctcccgtgtgcaccccaaggatcca
cacctatgctctgacgtagatgagtgccaagaccgtccctgcagccagacgtgtcgcaac
ttgctgggctcgtatgtgtgctcgtgtgtggagggttacatccttcgtgctgataagcac
tcctgcaaggccaactccaacattgagccgaagctcatcttcacgaatcgctactatatt
cgtgagctggacctgaatggaaagaacacactgcgtgcccacaacctggcaaatgccgtg
gcactggactatgactgggcagagcagtgcatctattggtctgacgttatggcactaggc
agcagcatcaagcgtctgtgtggctccagtgacagtgcctatcaggtgctgcactcggcc
acactgcagaaccctgacggactggctgttgactgggtgggccgcaacctctactggtgt
gacaagggcttggacacaattgaggtgtcgaagttggatggacgctaccgcaaagtgctg
atcaacacaggcttgcaggagccacgtgctatcacactggacccccgcaatgggtacatg
tactggacggattggggtgatagaccctacattggcaaagctggcatggatggctctgga
cagaggatactcgttaatgactccctgggatggccaaatgctctcaccatttcttatgaa
acaaacgaactgttttgggctgatgcacgagaagactacattgcagtctctgacctggaa
ggcaataacaggaaaataatactcagcagagaaagggattccaaggtgatgttgcaccat
atcttcgccctaacggtgctagaggactacctgtactggacagactgggagaccaagtcg
gtggaacgttgtcacaagtacaatggcacagactgcagcaccctgaccaccactgtgcac
cgccccatggacattcacgcctaccatcccctacgacaagtccctgtgtcaaacaatcca
tgcctgcacaacgcgggctgcagtactctgtgtttgctcagtcccaatcatggacatcag
tgtgcgtgcccagagaactacatcctggatgaggatggacggagctgcattgccaactgc
acaacagcacattacatatgtgcaactacatacaagtgcatcccattctggtggaaatgt
gacactcaggatgactgtggcgatggatcagatgagcacaaggactgtccgaagttcgag
tgcatgccaggccaattccagtgcaacaacacaaactgcattcatccctcacagctctgc
aatggggaatctgagtgtggcgatggctctgatgagatggattgcaaccagtacacctgc
ttgggcactcagttcaagtgcaagggcaatgcctctgtgtcagaccgctgcatcccactc
agcaagcaatgtgatggccacgcagactgtctggctgaggaggatgagcaagactgtcca
cccaagacatgtccaccaaatcagtactcgtgcaagaacaagaagtgcatcccatcagta
tgggaatgtgatggtgacaacgactgtggagacaactcggacgagaaccagaactgcaag
gagaggaaatgccctatagaccacttcaagtgtcagtcaggtcgctgcatccccaagtca
tggcaatgtgacggagatcatgattgctcccaaggagaagacgaacctgcatcttgcagt
tctgcggactttcacacatgtgatcccacgtacttcaagtgcaagaacaacaagtgcatt
ccaggacggtggcgctgtgactacgacaatgactgtggtgaccattctgatgaagatggt
tgtgtgccccgcaagtgctctgagtcagagtttcgatgcagtgatggccgctgcatccga
ggcatccaccactgtgatggcgagtacaattgtgatgatcacagtgacgagaacaactgc
aacacgacctgcaaccagaacgagtttcagtgccagaacccacactactgcatcttcatt
gaatggaagtgtgatggcgacacagactgcagtgatggctcagatgaggcgaactgcaat
gattcatgcccggacaatcagttcacatgccagaataagcagtgcattagcatctcgtgg
cgctgtgatggggatgatgactgtggcgacaactcagatgaaatgcagtgtgagagtctg
gcttgtccccctggacggcacaggtgcaagaaccacatctgcatctcacccatcaatgtt
tgtgatggcaaggacaactgtggtgatggttcagatgaggatccagttgtctgtcagcag
agtggtcactgcaccttggaccagttccgttgtgccaacaagaactgcatcagcaagaaa
ctacaatgtgattcgttcaatgactgtggcgacaattcggatgaggaaggttgcattcag
cctccctgccacttcggggcatgctcccagatctgtgtggaaaagaagggaggcaatttc
gcctgccattgtgcacctggcttcataggcgagggcacatcacggaacaagacctgcctg
gctaaaggaaaacctgcacatctcatggttgctggagaaacagatcttcgggatttgaac
ccttacaaagctggagagaattctcccacacagacactgagcaaacagttctctgaccca
ggacacaaagtagagtcaatggacatcctgtgggacccagccaaatcggccgtgttctgg
tctgaccaccacagcaagatgattcgacgctcctatctgtatgacatgccttctacacgc
acccgaccccggagggtgcagcgtgatgatatgaaagtactggccatgaatctggtggac
ccacgtggcctggcagtggactgggtgggcagacgtgtatactgggtagatgcaggacag
gatgttgtgatggtgtctgatctgactggcgagaagaagagtacgctgatcgacactgag
ctggaccagccccacgacattgttgtggacccacagtcggggctcatgttctggtcagac
tggggggtgaacagtcgcattgaatcagcatacatggatggaacaggtcgtcgagctctt
gtgaatactatggtccagtggccgacaggtctcgcaatagattacccagctagaaggctg
tactggacagaccccaaggcatacactgtggaaagtgtggatcttaatgggcaggatcgg
cagctcatcaaacggttcccacatcgtgaaaagccatacaaagtggaggtgtttgaggac
agcttgtacgtgagcacataccagaccaacaacatcattaagttgaacaagttcggccat
ggcaacttgacatacttggtacagggcctcaacagagcatctgatatcctcattgttcag
gagaacaagcagacaaagaacttgaagaacccatgtcacccatcaccatgccacaactca
acactctgtttattggggcccagcagccacacagagcccagcttctcttgtgtatgtcct
gatggcttggtcaaaacagttggcagtgacaataagagcagcagtgcacaggtggtctgt
ataccaacagtgcgaaccccaaaggtgtgtgacctcgattgccataagggtacatgccaa
atggtgaaggacaaaccagtgtgcaggtgtcagccgctgtatgatggtgaccgatgtcag
aatttccgttgctcacagtactgccggaacaaaggactttgctttgcagacctcctaaca
cctgttcccagtaacttaccaccacctctcaagtgtaactgtcctgcacaatggacaggt
gagcgttgtgaaattccagtgcatatgtgcgagaatcgatgtctcaacaatggtacctgc
ttcagtccgcgtccaggtttggctcagtgcaactgtctgccaggcttcacagggagtcgc
tgtgagaactgtgtcaacctgatgtgtcagaatggtggtgtctgcaaccgcacagatgga
ctggagcactgtgtctgtcagtctggctacagtggcactcactgtgaacattctgattgt
gatcaatattgtctacagggcacatgcagcctgacagcaagaggtcctgtatgtaactgt
ccaccaagcttcacaggcaagagatgtgagcatgatggctgcgttggccactgtcataat
ggaggaacgtgcatcccaggtgccaagacactaacatgtagctgccctccccgtttcacc
ggacgccgctgtgaggtggatttatgtaagtgtacgccatgccaggacctcaatgatcct
gactgcaagtgtcctgttgaacaacctgctgagtgccataactcttgctacccagatcag
tgtcttaatggaggtacatgcatcacagtgaatggagagcccttctgcaagtgcactggt
gagtatggaggcaaggactgctcactgcactatgggctgcagaacccatgccaagactac
tgcaagcagaatggcatctgcacattaactgcacacggacccatgtgtcactgcctggtg
ggctggacgggatcacgctgtgaggagaggtctgcatgtaagggatactgcttcaatgga
ggcacctgtcaggagtcccctgaccccagcctcaagcccagctgcatatgcccgagcacg
aacacaggtgaccgctgccagtcaccagtgctggatttctcggtggcgcgtggggcagag
ggtaacaactacaccatggtgatggtggtgaccgtggcattgacattccttctggtgctg
gtgggctcattagtgcttgcatgctacatgctgcggcgccggcgtagtggcaagcccttt
atgcacgtgcgcatgcacgagaatgtggagatcagcaaccccatgtacctgcgggaggag
gtggatgatgatgctgatgcacttgacggaaacttcagcctggatgccgacaagagtggc
aactttgcaaatccagtgtacgactcactgtacaatgttggttcaacgggaaatggcacc
acaagtgtcagcgaggagaagaagggactgctgcagcgagccagcaaggagggccagcac
ccttctacagacaccagggacagcctctag

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