Periplaneta americana (American cockroach): 138704876
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Entry
138704876 CDS
T10946
Symbol
Gclc
Name
(RefSeq) glutamate--cysteine ligase isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
pame Periplaneta americana (American cockroach)
Pathway
pame00270
Cysteine and methionine metabolism
pame00480
Glutathione metabolism
pame01100
Metabolic pathways
pame01240
Biosynthesis of cofactors
Module
pame_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
pame00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
138704876 (Gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
138704876 (Gclc)
Enzymes [BR:
pame01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
138704876 (Gclc)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
138704876
NCBI-ProteinID:
XP_069689340
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All DBs
Position
8:88691999..88791011
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AA seq
646 aa
AA seq
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MGLLTEGSPLSWEETKALAEHVRQHGVVQFINLYKRLRDRQGDVLKWGDEVEYILVKFDH
ERKVARVSLRASDILNTLQEKELKNPHGVKSLWRPEYGAYMVEGTPGKPYGGLLAHFNIV
EANMKYRREEVARLLNPGEAVMSLTSFPRLGSPNFTDPPTVPTPDNGASRSLFFPDDAIF
QGHPRFKTLTRNIRQRRGSKVAINLPIFRDKKTPNPFVEDLKALGDDGESTETALPNHVY
MDAMGFGMGCCCLQLTFQACNINEARTLYDQLTPLCPIMLALTAASPLHRGYVTDVDCRW
NVISCSVDCRTREERGEVPLKHNKFRIPKSRYDSIDSYLSPHGEKYNDVPLIYDEAIYQQ
LRDADIDHLLAQHIAHLFIRDSVSLFSEKVNQDDEQDTDHFENIQSTNWQTMRFKPPPPN
SPIGWRVEFRPCEVQITDFENAAIVCFVVLLTRVILSYQLNFIIPISKVDENMRRAQKRD
ALRQEEFYFRKDITTCVSPPAATSCCHTSDCSDVYTPMTIDQIINGKADEFPGLIPLINS
YLSGMDVDADTHCTIQQYLKLIQRRASGDLQTTASWMRRFVQSHPDYRHDSVVSERINYD
LLTQIHGIQTGEIPCPELLGTSLQSKTQESIPAALEKAEAINGECC
NT seq
1941 nt
NT seq
+upstream
nt +downstream
nt
atgggtttgttaacagaaggaagtccactaagctgggaagaaacaaaggctttagcagaa
catgtaagacaacacggtgtggtgcaatttattaatttatataaacgccttcgtgaccgt
caaggagatgtattaaaatggggtgatgaggtggaatacattctagtgaagtttgatcat
gaaagaaaagttgcacgagtttcccttcgagcttcagatattctgaacacattgcaggag
aaagaactcaagaatccacatggtgtcaaatcactttggaggccagagtatggagcatat
atggttgagggtacaccaggaaaaccatatggaggactgcttgcacattttaatattgtt
gaagcaaacatgaagtatcgcagggaggaagtagcaagattgctaaatccaggggaggct
gtgatgtctcttacaagttttcccaggcttggttctcctaatttcacagatcctcctaca
gttcctacgccagataatggtgcatcacgttctctcttttttcccgacgatgcaatattc
caaggacatccacgctttaaaacacttactagaaatattcggcaaagaagaggatcaaag
gttgctataaaccttcctatcttcagagacaagaaaactccaaatccttttgtggaagat
ctgaaagctctgggagatgatggagaatctactgagacagcattaccaaaccatgtgtat
atggatgcaatgggttttggcatggggtgctgttgtctacaacttacattccaagcttgc
aatataaatgaagcaagaacactttacgaccaacttacacctctttgccccattatgttg
gcattgacagcagcatcaccattgcatcgaggctatgtaacagatgtagattgtcgatgg
aatgttatttcatgttcagtggactgtcgcactagagaagagaggggcgaagttccatta
aaacacaacaaatttagaatacccaaatcccgttatgattccattgattcatatctatca
ccacatggagaaaaatacaatgatgtgcctttgatatatgatgaggcaatatatcagcag
cttcgtgatgcagatatcgaccacttactagcacagcatatagcacatttgttcataaga
gattctgtgtcacttttcagtgagaaggtcaatcaagatgatgaacaggacacagatcat
tttgagaatattcagtcaactaattggcagacaatgaggttcaaaccaccacctccgaat
tcacctattggctggagagtggaattccgaccatgtgaagtgcagattacggattttgaa
aatgcagcaattgtgtgctttgtggttcttctcaccagggtgattctctcttaccaactt
aacttcattatacccatcagcaaggttgatgagaacatgaggcgcgcccagaaacgtgat
gctctgcggcaggaagaattttattttcgtaaagatatcacaacttgtgtttccccgcct
gctgctacctcatgctgccacaccagtgactgcagtgatgtgtatacacccatgacaatt
gatcagatcatcaatggcaaggcagatgaatttcctggacttataccacttatcaacagt
tacctgagtggaatggatgtggatgcagacacccactgcaccattcaacagtacttaaaa
ctaattcaacgacgagcatcaggtgacttgcagaccacagcaagctggatgaggcgattt
gtccagtcacatccagattatagacatgattctgtggtgagtgaacgtataaattatgac
ctcctaactcagattcatggaatacagactggtgaaattccttgtcctgaactgttgggc
acaagtctacagtcaaaaactcaagaatcaattcctgcagcacttgaaaaggctgaagcg
ataaatggtgaatgttgctga
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