KEGG   Papio anubis (olive baboon): 101001103
Entry
101001103         CDS       T07474                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X2
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
panu  Papio anubis (olive baboon)
Pathway
panu01522  Endocrine resistance
panu04010  MAPK signaling pathway
panu04015  Rap1 signaling pathway
panu04068  FoxO signaling pathway
panu04071  Sphingolipid signaling pathway
panu04114  Oocyte meiosis
panu04148  Efferocytosis
panu04218  Cellular senescence
panu04261  Adrenergic signaling in cardiomyocytes
panu04370  VEGF signaling pathway
panu04380  Osteoclast differentiation
panu04517  IgSF CAM signaling
panu04550  Signaling pathways regulating pluripotency of stem cells
panu04611  Platelet activation
panu04613  Neutrophil extracellular trap formation
panu04620  Toll-like receptor signaling pathway
panu04621  NOD-like receptor signaling pathway
panu04622  RIG-I-like receptor signaling pathway
panu04625  C-type lectin receptor signaling pathway
panu04657  IL-17 signaling pathway
panu04658  Th1 and Th2 cell differentiation
panu04659  Th17 cell differentiation
panu04660  T cell receptor signaling pathway
panu04664  Fc epsilon RI signaling pathway
panu04668  TNF signaling pathway
panu04670  Leukocyte transendothelial migration
panu04714  Thermogenesis
panu04722  Neurotrophin signaling pathway
panu04723  Retrograde endocannabinoid signaling
panu04728  Dopaminergic synapse
panu04750  Inflammatory mediator regulation of TRP channels
panu04912  GnRH signaling pathway
panu04914  Progesterone-mediated oocyte maturation
panu04917  Prolactin signaling pathway
panu04926  Relaxin signaling pathway
panu04932  Non-alcoholic fatty liver disease
panu04933  AGE-RAGE signaling pathway in diabetic complications
panu04935  Growth hormone synthesis, secretion and action
panu04936  Alcoholic liver disease
panu05014  Amyotrophic lateral sclerosis
panu05020  Prion disease
panu05022  Pathways of neurodegeneration - multiple diseases
panu05132  Salmonella infection
panu05133  Pertussis
panu05135  Yersinia infection
panu05140  Leishmaniasis
panu05142  Chagas disease
panu05145  Toxoplasmosis
panu05152  Tuberculosis
panu05161  Hepatitis B
panu05163  Human cytomegalovirus infection
panu05167  Kaposi sarcoma-associated herpesvirus infection
panu05169  Epstein-Barr virus infection
panu05170  Human immunodeficiency virus 1 infection
panu05171  Coronavirus disease - COVID-19
panu05205  Proteoglycans in cancer
panu05208  Chemical carcinogenesis - reactive oxygen species
panu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
panu05415  Diabetic cardiomyopathy
panu05417  Lipid and atherosclerosis
panu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:panu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101001103 (MAPK12)
   04015 Rap1 signaling pathway
    101001103 (MAPK12)
   04370 VEGF signaling pathway
    101001103 (MAPK12)
   04668 TNF signaling pathway
    101001103 (MAPK12)
   04068 FoxO signaling pathway
    101001103 (MAPK12)
   04071 Sphingolipid signaling pathway
    101001103 (MAPK12)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    101001103 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    101001103 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    101001103 (MAPK12)
   04218 Cellular senescence
    101001103 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    101001103 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101001103 (MAPK12)
   04613 Neutrophil extracellular trap formation
    101001103 (MAPK12)
   04620 Toll-like receptor signaling pathway
    101001103 (MAPK12)
   04621 NOD-like receptor signaling pathway
    101001103 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    101001103 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    101001103 (MAPK12)
   04660 T cell receptor signaling pathway
    101001103 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    101001103 (MAPK12)
   04659 Th17 cell differentiation
    101001103 (MAPK12)
   04657 IL-17 signaling pathway
    101001103 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    101001103 (MAPK12)
   04670 Leukocyte transendothelial migration
    101001103 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    101001103 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    101001103 (MAPK12)
   04917 Prolactin signaling pathway
    101001103 (MAPK12)
   04926 Relaxin signaling pathway
    101001103 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    101001103 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101001103 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    101001103 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    101001103 (MAPK12)
   04722 Neurotrophin signaling pathway
    101001103 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101001103 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101001103 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    101001103 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    101001103 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    101001103 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101001103 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101001103 (MAPK12)
   05161 Hepatitis B
    101001103 (MAPK12)
   05171 Coronavirus disease - COVID-19
    101001103 (MAPK12)
   05163 Human cytomegalovirus infection
    101001103 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101001103 (MAPK12)
   05169 Epstein-Barr virus infection
    101001103 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101001103 (MAPK12)
   05135 Yersinia infection
    101001103 (MAPK12)
   05133 Pertussis
    101001103 (MAPK12)
   05152 Tuberculosis
    101001103 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101001103 (MAPK12)
   05140 Leishmaniasis
    101001103 (MAPK12)
   05142 Chagas disease
    101001103 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101001103 (MAPK12)
   05020 Prion disease
    101001103 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    101001103 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101001103 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    101001103 (MAPK12)
   05415 Diabetic cardiomyopathy
    101001103 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101001103 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    101001103 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101001103 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101001103 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:panu01001]
    101001103 (MAPK12)
Enzymes [BR:panu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     101001103 (MAPK12)
Protein kinases [BR:panu01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   101001103 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Kinase-like Haspin_kinase
Other DBs
NCBI-GeneID: 101001103
NCBI-ProteinID: XP_003905793
Ensembl: ENSPANG00000016972
UniProt: A0A096NL07
LinkDB
Position
16:463530..473152
AA seq 367 aa
MSSPPPARSGFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHEKLGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMK
VTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRV
TAAEALAHPYFESLHDKEDEPQVQKYDDSFDDVDRTLDEWKRVTYKEVLSFKPPRQLGAR
VSKETAL
NT seq 1104 nt   +upstreamnt  +downstreamnt
atgagctctccgccgcctgcccgcagtggcttttaccgccaggaggtgaccaagacggcc
tgggaggtgcgcgccgtgtaccgggacctgcagcccgtgggctcgggcgcctatggcgcg
gtgtgctcggccgtggacagccgcaccggcgctaaggtggccatcaagaagctgtaccgg
cccttccagtccgagctgttcgccaagcgcgcctaccgcgagctgcgcctgctcaagcac
atgcgccacgagaacgtgattgggctgctggatgtgttcactcctgatgagaccctggat
gactttacagacttttacctggtgatgccattcatgggcaccgacctgggcaagctcatg
aaacatgagaagctgggcgaggaccggatccagttcctcgtgtaccagatgctgaagggg
ctgaggtatatccatgctgccggcatcatccacagagacctgaagcctggcaacctggct
gtgaacgaagactgtgagctgaagatcctggactttggcctggccaggcaggcagacagc
gagatgactggctatgtggtgacccggtggtaccgggcacccgaggtcatcttgaattgg
atgcgctacacgcagacggtggacatctggtctgtggggtgcatcatggcggagatgatc
acaggcaagacgctgttcaagggcagcgaccacctggaccagctgaaggagatcatgaaa
gtgacagggacgcctccagctgagtttgtgcagcggctgcagagtgatgaggccaagaac
tacatgaagggcctccctgagttggagaagaaggattttgcctccatcctgaccaatgca
agccctctggctgtgaacctcctggagaagatgctggtgctggatgcggagcagcgggtg
acggcagccgaggcactggcccatccctacttcgagtccctgcatgacaaggaagatgag
ccccaggtccagaagtatgacgactcctttgatgacgtggaccgcacgctggatgaatgg
aagcgtgttacttacaaagaggtgctcagcttcaagcctccgcggcagctgggagccagg
gtctccaaggagacggctctgtga

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