Papio anubis (olive baboon): 101004987
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Entry
101004987 CDS
T07474
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
panu
Papio anubis (olive baboon)
Pathway
panu00790
Folate biosynthesis
panu01100
Metabolic pathways
panu01240
Biosynthesis of cofactors
panu01523
Antifolate resistance
panu04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
panu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
101004987 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
101004987 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101004987 (FPGS)
Enzymes [BR:
panu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
101004987 (FPGS)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
101004987
NCBI-ProteinID:
XP_009187385
Ensembl:
ENSPANG00000024843
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Position
13:97283299..97297260
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AA seq
588 aa
AA seq
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MSRARNHLRAALFLAAASARGVTTQVAAQRGLSAWPVPQEPSMEYQDAVRMLNTLQTNAG
YLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGSCVSMPPYFRF
LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIA
WQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPTLEDLEEGGPPLALGLDGE
HQRSNAALALQLAHCWLQRQDHHGAREVKASRPGLLWQLPLAPVFQPTSHMRLGLRNTEW
LGRTQVLRRGPLTWYLDGAHTPSSVQACVRWFRQALQGRERPSGSGPEVRVLLFNATGDR
DPAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQQHWNHLDE
EQASPDLWSAPSPEPGGPTSLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPVFQPPT
PPKGLLTHPVAHSGASVLHEAAAIHVLVTGSLHLVGGVLKLLEPALSQ
NT seq
1767 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcgcggaaccacctgcgcgccgctctattcctggcagcggcgtctgcgcgc
ggcgtaacgacccaggtcgcggcgcagcggggcttgagcgcgtggccggtgccgcaggag
cccagcatggagtaccaggatgccgtgcgcatgcttaataccctgcagaccaatgccggc
tacctggagcaggtgaagcgccagcggggtgacccccagacacagctggaagccatggaa
ctgtacctggcacggagtgggctgcaggtagaggacttggaccggctgaacatcatccat
gtcactgggacgaaggggaagggctccacttgtgccttcacggaatgtatcctccgaagc
tatggcctgaagacgggattctttagctctccccacctggtgcaggttcgggagcggatc
cgcatcaacgggcagcccatcagtcccgagctcttcaccaagtacttctggcgcctctac
caccggctggaggagaccaaggatggcagctgtgtctccatgcccccctacttccgcttc
ctgacacttatggccttccacgtcttcctccaagagaaggtggacctggcagtggtggag
gtgggcattggcggggcttatgactgcaccaacatcatcaggaagcctgtggtgtgcggc
gtctcttctcttggcatcgaccacaccagcctcctgggggacacggtggagaagatcgca
tggcagaaagggggcatctttaagcaaggcgtccctgccttcactgtgctccaacctgaa
ggtcccctggcagtgctgagggaccgagcccagcagatctcatgtcctctctacctgtgt
ccgacgctggaggacctggaggaaggggggccgccgctggccctgggcctggacggggag
caccagcggtccaatgccgccttggccttgcaactggcccactgctggctgcagcggcag
gaccaccatggtgcccgggaggtgaaggcatccaggccggggctcctgtggcagctgccc
ctggcacccgtgttccagcccacatcccacatgcggctcgggcttcggaacacggagtgg
ctggggcggacacaggtgctgcggcgcgggccccttacctggtacctggacggcgcgcac
actcccagcagcgtgcaggcctgcgtgcgctggttccgccaggcgctgcagggccgagag
aggccgagcggcagtgggcccgaggttcgagtcttgctcttcaatgctaccggggaccgg
gacccggcggccttgctgaaactgctgcagccgtgccagtttgactatgccgtcttctgc
cccaacctgacagaggtgtcatccacaggcaatgcagaccaacagaacttcacggtgaca
ctggaccaggttctgctccgctgcctggaacaccagcagcactggaaccacctggacgaa
gagcaggccagcccggacctctggagcgcccccagcccagagcctggtgggcccacatcc
ctactgctggcgccccacccaccccacacctgcagcgccagctccctcgtcttcagctgt
atttcacatgccttgcaatggatcagccaaggccgagaccctgtcttccagccacccact
cccccaaagggcctcctcacccaccctgtggctcacagtggggccagcgtactccatgag
gctgctgccatccatgtgctggtcactggcagcctgcacttggtgggtggtgtcctgaag
ctgctggagcctgcactgtcccagtag
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