Papio anubis (olive baboon): 101014060 Help Entry 101014060         CDS       T07474                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism panu  Papio anubis (olive baboon) Pathway panu04020   Calcium signaling pathway panu04371   Apelin signaling pathway panu04713   Circadian entrainment panu04921   Oxytocin signaling pathway panu04970   Salivary secretion panu05010   Alzheimer disease panu05012   Parkinson disease panu05020   Prion disease panu05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:panu00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     101014060 (RYR3)    04020 Calcium signaling pathway     101014060 (RYR3)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     101014060 (RYR3)   09154 Digestive system    04970 Salivary secretion     101014060 (RYR3)   09159 Environmental adaptation    04713 Circadian entrainment     101014060 (RYR3)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     101014060 (RYR3)    05012 Parkinson disease     101014060 (RYR3)    05020 Prion disease     101014060 (RYR3)    05022 Pathways of neurodegeneration - multiple diseases     101014060 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:panu04040]     101014060 (RYR3) Ion channels [BR:panu04040]  Voltage-gated cation channels   Ryanodine receptor    101014060 (RYR3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 MIR SPRY Ins145_P3_rec RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_5 EF-hand_8 Motif Other DBs NCBI-GeneID:  101014060 NCBI-ProteinID:  XP_021797391 Ensembl:  ENSPANG00000019876 LinkDB All DBs Position 7:complement(153078971..153648705) Genome browser AA seq 4889 aa AA seqDB search MIKQLTFGHSRGTQRPSGIQVDAPMVLQNSILPSYVEDEVVLQCIATIHKEQRKFCLAAE GLGNRLCFLEPTSEAKYIPPDLCVCNFVLEQSLSVRALQEMLANTGENGGEGAAQGGGHR TLLYGHAILLRHSFSGMYLTCLTTSRSQTDKLAFDVGLREHATGEACWWTIHPASKQRSE GEKVRIGDDLILVSVSSERYLHLSLSNGNIQVDASFMQTLWNVHPTCSGSSIEEGYLLGG HVVRLFHGHDECLTIPSTDQNDSQHRRIFYEAGGAGTRARSLWRVEPLRISWSGSNIRWG QAFRLRHLTTGHYLALTEDQGLILQDRAKADTKSTAFSFRASKELKEKLDSSHKRDIEGM GVPEIKYGDSVCFVQHIASGLWVTYKAQDAKTSRLGPLKRKVILHQEGHMDDGLTLQRCQ REESQAARIIRNTTALFSQFVSGNNRTAAPITLPIEEVLQTLQDLIAYFQPPEEEMRHED KQNKLRSLKNRQNLFKEEGMLALVLNCIDRLNIYNSVAHFAGIAREESGMAWKEILNLLY KLLAALIRGNRNNCAQFSNNLDWLISKLDRLESSSGILEVLHCILTESPEALNLIAEGHI KSIISLLDKHGRNHKVLDILCSLCLCNGVAVRANQNLICDNLLPRRNLLLQTRLINDVTS IRPNIFLGVAEGSAQYKKWYFELIIDQVDPFLTAEPTHLRVGWASSSGYAPYPGGGEGWG GNGVGDDLYSYGFDGLHLWSGRIPRAVASINQHLLRSDDVVSCCLDLGVPSISFRINGQP VQGMFENFNTDGLFFPVMSFSAGVKVRFLMGGRHGEFKFLPPSGYAPCYEALLPKEKMRL EPVKEYKRDADGVRDLLGTTQFLSQASFIPCPIDTSQVVLPPHLEKIRDRLAENIHELWG MNKIELGWTFGKIRDDNKRQHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIAHVN PAAEEDLKKVKLPKNYMMSNGYKPAPLDLSDVKLLPPQEILVDKLAENAHNVWAKDRIKQ GWTYGIQQDLKNKRNPRLVPYALLDERTKKSNRDSLREAVRTFVGYGYNIEPSDQELADS AVEKVSIDKIRFFRVERSYAVRSGKWYFEFEVVTGGDMRVGWARPGCRPDVELGADDQAF VFEGSRGQRWHQGSGYFGRTWQPGDVVGCMINLDDASMIFTLNGELLITNKGSELAFADY EIENGFVPICCLGLSQIGRMNLGTDASTFKFYTMCGLQEGFEPFAVNMNRDVAMWFSKRL PTFVNVPKDHPHIEVMRIDGTMDSPPCLKVTHKTFGTQHSNADMIYCRLSMPVECHSSFS HSPCLDSEAFQKRKQMQEILSHTTTQCYYAIRIFAGQDPSCVWVGWVTPDYHLYSEKFDL NKNCTVTVTLGDERGRVHESVKRSNCYMVWGGDIVASSQRSNRSNVDLEIGCLVDLAMGM LSFSANGKELGTCYQVEPNTKVFPAVFLQPTSTSLFQFELGKLKNAMPLSAAIFKSEEKN PVPQCPPRLDVQTIQPVLWSRMPNSFLKVESERVSERHGWVVQCLEPLQMMALHIPEENR CVDILELCEQEDLMRFHYHTLRLYSAVCALGNSRVAYALCSHVDLSQLFYAIDNKYLPGL LRAGFYDLLISIHLANAKERKLMMKNEYIIPITSTTRNIRLFPDESKRHGLPGVGLRTCL KPGFRFSTPCFVATGEEHQKQSPEIPLESLRTKALSMLTEAVQCSGAHIRDPVGGSVEFQ FVPVLKLIGTLLVMGVFDDDDVRQILLLIDPSVFGEHSAETEEGTEKEEVTQVEEKAVEA GEKAGKEAPVKGLLQTRLPESVKLQMCELLSYLCDCELQHRVEAIVAFGDIYVSKLQANQ KFRYNELMQALNMSAALTARKTKEFRSPPQEQINMLLNFQLGENCPCPEEIREELYDFHE DLLLHCGVPLEEEEEEEEDTSWTGKLRALVYKIKGPPKPEKEQPTEEEERCPTTLKELIS QTMICWAQEDQIQDAELVRMMFNLLRRQYDSIGELLQALRKTYTISHASVSDTINLLAAL GQIRSLLSVRMGKEEELLMINGLGEIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLSTEK SQIAFPKMVASCCRFLCYFCRISRQNQKAMFEHLSYLLENSSVGLASPSMRGSTPLDVAA SSVMDNNELALGLEEPDLEKVVTYLAGCGLQSCPMLLAKGYPDVGWNPIEGERYLSFLRF AVFVNSESVEENASVVVKLLIRRPECFGPALRGEGGNGLLAAMQGAIKISENPALDLPSQ GYKREVSTEADEEEEEIVHMGNAIMSFYSALIDLLGRCAPEMHLIQTGKGEAIRIRSILR SLVPTEDLVGIISIPLKLPSLNKDGSVSEPDMAANFCPDHKAPMVLFLDRVYGIKDQTFL LHLLEVGFLPDLRASASLDTVSLSTTEAALALNRYICSAVLPLLTRCAPLFAGTDHCTSL IDSTLQTIYRLSKGRSLTKAQRDTIEECLLAICNHLRPSMLQQLLRRLVFDVPQLNEYCK MPLKLLTNHYEQCWKYYCLPSGWGSYGLAVEEELHLTEKLFWGIFDSLSHKKYDPDLFRM ALPCLSAIAGALPPDYLDTRITATLEKQISVDADGNFDPKPINTVNFSLPEKLEYIVTKY AEHSHDKWACDKSQSGWKYGISLDENVKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLA VGWTVERTKEGEALVQQRENEKLRSVSQANQGNSYSPAPLDLSNVVLSRELQGMVEVVAE NYHNIWAKKKKLELESKGGGSHPLLVPYDTLTAKEKFKDREKAQDLFKFLQVNGVIVSRG MKDMELDASSMEKRFAYKFLKKILKYVDSAQEFIAHLEAIVSSGKTEKSPHDQEIKFFAK VLLPLVDQYFTNHRLYFLSSPLKPLSSSGYASHKEKEMVASLFCKLAALVRHRISLFGSD STTMVSCLHILAQTLDTRTVMKSGSELVKAGLRAFFENAAEDLEKTSENLKLGKFTHSRT QIKGVSQNINYTTVALLPILTSIFEHVAQHQFGMDLLLGDVQISCYHILCSLYSLGTGKN IYVERQRPALGECVASLAAAIPVAFLEPTLNRYNPLSVFNTKTPRERSILGIPDTVEDMC PDIPQLEGLMKEINDLAESGARYTEMPHVIEVILPMLCNYLSYWWERGPENLPPSTGQCC TKVTSEHLSLILGNILKIINNNLGIDEASWMKRIAVYAQPIISKARPDLLRSHFIPTLEK LKKKAVKTVQEEEQLRADGKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSNWL KSPDADSDQLFRMVAEVFILWCKSHNFKREEQNFVIQNEINNLAFLTGDSKSKMSKAMQV KSGGQDQERKKTKRRGDLYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKSRYGHRD TDEEVREHLRNNLHLQEKSDDPAVKWQLNLYKDVLKSEEPFNPEKTVERVQRISAAVFHL EQVEQPLRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLHGYQRFWIETEE YSFEEKLVQDLAKSPKVEEEEEEETKKQPDPLHQIILYFSRNALTERSKLEDDPLYTSYS SMMAKSCQSGEDEEEDEDKEKTFEEKEMEKQKTLYQQARLHERGAAEMVLQMISASKGEM SPMVVETLKLGIAILNGGNAGVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQ NKAEGLGMVTEEGTLIVRERGEKVLQNDEFTRDLFRFLQLLCEGHNSDFQNFLRTQMGNT TTVNVIISTVDYLLRLQESISDFYWYYSGKDIIDESGQHNFSKALAVTKQIFNSLTEYIQ GPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELLDLLQDMVVMLLSL LEGNVVNGTIGKQMVDTLVESSTNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGIISK REFQKAMEGQKQYTQSEIDFLLSCAEADENDMFNYIDFVDRFHEPAKDIGFNVAVLLTNL SEHMPNDSRLKCLLDPAESVLNYFEPYLGRIEIMGGAKKIERVYFEISESSRTQWEKPQV KESKRQFIFDVVNEGGEQEKMELFVNFCEDTIFEMQLASQISESDSADRPEEEEEDEDSS YVLEIAGEEEEDGSFEPASAFAMACASVKRNVADFLKRATLKNLRKQYRNVKKMTAKELV KVLCSFFWMLFLGLFQMLFTILGGIFQILWSTVFGGGLVEGAKNIRVTKILGDMPDPTQF GIHDDTMEAERAEVMEPGITTELVHFIKGEKGDTDIMSDLFGLHPKKEGSLKHGPEVGLG DLSEIIGKDEPPTLESTVQKKRKAQAAEMKAANEAEGKVESEKADMEDGEKEDKDKEEEQ AEHLWTEVTKKKKRRCGQKAEKPEAFTANFFKGLDIYQTKLLHYLARNFYNLRFLALFVA FAINFILLFYKVTEEPLEEETEDVANLWNSFNDEEEEEAMVFFVLQESTGYMAPTLRALA IIHTIISLVCVVGYYCLKVPLVVFKREKEIARKLEFDGLYITEQPSEDDIKGQWDRLVIN TPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKNALDFSPVEETKAEAASLVSWL SSIDMKYHIWKLGVVFTDNSFLYLAWYTTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILS SVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDDDEPDMKCDDMMTCYLFHMY VGVRAGGGIGDEIEDPAGDPYEMYRIVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQE QVREDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQES YVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14670 nt NT seq  +upstreamnt  +downstreamnt atgattaaacagcttacttttgggcactctagaggaacacaaagaccatcagggatccaa gtggatgcaccaatggtgttacagaactccattcttccttcttatgtggaggatgaagtg gtactccagtgcatcgccaccattcacaaggagcagaggaagttctgcctggcagccgag ggacttgggaatcgcctgtgcttcttggaacccacttcagaagccaagtacattcctcca gatctctgcgtctgcaattttgtgctggaacagtccctatctgtcagagccctgcaggaa atgcttgccaacacaggtgaaaatggcggcgaaggggcagcacaaggaggtggccacagg accctgttatatggccatgcaattctcctgaggcactctttcagcggaatgtatctaaca tgcttgactacatcaagatcccagacagacaaacttgcctttgatgtaggtctacgggaa catgccacaggagaagcctgttggtggactatacatcctgcttccaaacagaggtccgaa ggagagaaagttagaattggcgatgacctcatcctcgtcagcgtgtcctctgaaagatac cttcatctctcactatcaaatggtaacatacaagtggatgcctcctttatgcagaccctc tggaatgtacatcctacgtgctcaggaagtagcatcgaagaaggatacctacttggtggg cacgtagtgcgtcttttccatggtcatgatgagtgtctgacgataccatctacagaccag aatgattcccagcacaggaggatattctacgaagctgggggagctgggactcgagccagg tctctgtggagagtggaaccacttcggataagttggagtggcagtaacatcagatggggc caggcttttcgactccggcatctcaccacaggccactacctggccttgacagaagaccaa ggccttatactacaagaccgggcaaaggcagacaccaagtccacagctttctctttccgg gcatcaaaggaactcaaggagaaattagattccagtcacaagcgagacatagaaggcatg ggagttccggaaatcaagtatggagattctgtctgctttgtacagcatatagccagtggt ctgtgggtgacctacaaagcacaagatgccaaaacttcccgcctgggacctctgaagaga aaggtcatactccatcaggaaggccacatggatgatggattaacactgcagagatgccag cgtgaggagtcccaggctgctcggatcatccggaacactacagccttattcagccagttt gtcagcggaaacaatcgcacagctgcccccatcaccctgcctatagaagaagtcctgcag accctacaggacttgatcgcctacttccagcccccggaggaggagatgcgacatgaagac aagcagaacaagctccgctcactcaaaaacagacaaaatcttttcaaggaagagggaatg ttggctcttgtcttaaattgcattgaccgcttaaatatctacaatagcgtagcacacttt gcagggattgcaagggaagagagtggcatggcctggaaagaaattctgaacctcctctac aaattgctggctgctctcattcgtggaaacagaaacaattgcgctcaattctccaataac cttgattggctcatcagtaaattggacagactagaatcttcctcaggtatcttggaagtt ttgcactgcatcttaactgaaagtccggaagccttaaatctgatagcagagggccacatc aagtccatcatctccctgttggataagcacgggcggaatcacaaggttctggatatcctg tgctccctctgtctctgcaatggggttgcagtgagagccaaccagaatctgatctgtgac aacctgctgccccggagaaacctgctcttgcagacacgactgattaacgatgtaaccagt atccggccaaacatcttcctgggagtcgcggagggctcagcccagtacaagaagtggtac ttcgagctgattatcgaccaggtggaccccttcctaacagcagagcccacacatctgcgg gtgggctgggcctcttcctcaggctatgctccatacccaggcggtggagaaggatgggga ggcaatggtgttggcgatgacctgtactcctatggctttgatggacttcacctttggtca ggccggatacccagagctgtggcttccatcaaccagcacctcctgagatcagatgatgtg gtaagctgctgcctggacctcggggtgcccagcatttcattccgcatcaatggacaacct gtgcaggggatgtttgagaacttcaacacagacgggctcttcttccctgtgatgagcttt tcagcaggtgttaaagtacgtttcctgatgggtggacgtcatggagagtttaagttcctg ccaccctctggctatgccccttgctatgaagccttacttccaaaagagaagatgagattg gaacctgtcaaagaatataaacgtgatgctgatggcgttagagatctcttgggtaccacc cagttcctatcccaagcctctttcatcccatgccccatagacaccagtcaggttgttttg ccacctcacctcgaaaagatccgagacagactagctgaaaacatccacgagctttgggga atgaataaaatagagcttggctggactttcggcaagatacgagatgacaataaaagacaa cacccttgccttgtggagttttcaaagctccccgaaactgagaagaattataacctgcaa atgtcgactgaaaccttgaaaaccctcctggccctggggtgccacattgctcatgttaac ccagctgctgaggaggatctcaagaaggtcaaactgcccaaaaactatatgatgtccaat ggctataagccagcccctttggatttgtctgatgtgaagctgttacctcctcaagaaatt ttagtggataagcttgcagaaaatgcgcacaatgtttgggcaaaagacagaataaaacaa ggatggacctatggcatccaacaggatttgaagaacaaaagaaatccccgtctggtgcca tatgcattactggacgagcgtaccaagaagtcaaacagggacagcctgagggaagctgtg cgcacttttgttggttacggatataacattgagccatcagaccaagaactagctgactcg gctgtggagaaagtcagcatagacaagatccgatttttccgggtagagcgatcttacgca gtgagatctggaaagtggtattttgagtttgaggtggtgactggaggagacatgcgagtt ggctgggccaggccaggctgtcggcctgatgtggaactgggggccgatgaccaagccttt gtgtttgaaggcagcaggggccagcgttggcatcaaggaagtgggtattttgggcgtacg tggcagccaggagatgtggtcggatgtatgattaacctggatgatgcttcaatgatcttc acgctgaatggggagctcctgatcaccaacaaaggctctgaacttgccttcgctgactac gagattgagaatggctttgtgcccatctgctgtctggggctgtctcagattggccgcatg aatctcgggacagatgccagtaccttcaagttttataccatgtgcggtctccaagagggc tttgagccttttgctgtcaacatgaacagagatgttgctatgtggttcagcaagcgcctc ccgacgtttgtcaacgtgccaaaggaccatccacacatagaggtcatgaggattgatggc accatggacagccctccgtgtctcaaggtgacccataagacatttggcacacagcatagc aatgccgacatgatctactgccgcttgagcatgcctgtcgagtgccactcttccttcagc cacagcccctgtctggacagtgaagctttccagaaaaggaaacagatgcaagaaatactc tctcatacaacaacacagtgctactatgccatccgcatctttgctggacaggatccatcc tgcgtctgggtcggatgggtgactccagactatcacttgtacagtgaaaagtttgacctg aataaaaactgcacagtgactgtcaccctaggggatgaaagaggccgggtacacgaaagt gtgaaacgcagcaactgctacatggtctggggcggggacatagtggccagttcccagaga tcaaatcggagtaacgtggacctggagatcggctgtcttgtggatctggcaatgggcatg ttgtccttctcagccaatggaaaagaactgggcacctgctaccaggtggagcccaacacc aaagtgtttccggcagtcttcctgcagcctacaagtacttccttgtttcagttcgaactt ggaaagctgaagaatgcaatgcccctgtcggcggccatattcaagagtgaagagaagaac ccagtcccacagtgtccacctcggctggacgtccaaaccatccagcccgtgctctggagc cgcatgcccaatagcttcctgaaggtggagagcgagcgtgtgagcgagcgccatggctgg gtggtgcagtgcctggagcccctgcagatgatggcgctccacatccccgaggagaacagg tgtgtggatatcctggagctctgtgagcaggaggacctgatgcggttccattaccacacg ctgaggctctacagtgcggtgtgcgccctgggaaacagccgcgtggcctatgccctgtgc agccacgtggacctctcccagctcttctatgccattgacaacaagtacctccctggcctc cttcgagctggcttctatgacctgctcatcagcatccacctggccaacgccaaggagagg aagctgatgatgaagaacgagtacatcatccccattaccagcaccaccaggaatatccgc ctcttcccggacgagtccaagaggcatggactgcctggggtgggcctgagaacatgtctc aagcctgggttcaggttctccaccccttgctttgtcgcgactggtgaggagcaccaaaaa cagagccctgagattcccttggagagtctcaggacgaaggctctgagtatgctgacagag gcagtgcagtgcagcggggcccacatccgagaccccgtaggggggtctgtggagttccag tttgtgcctgtgctgaaactcattggaaccctgctggtcatgggcgtgtttgatgatgac gatgttcggcagatcctcctcctgattgatccctctgtgtttggggagcatagtgcggag acagaggagggaacagaaaaggaggaagtgacccaagtggaggagaaggctgtggaggct ggggagaaggccggcaaggaggctcctgtcaaaggcttgttgcagactcgattacccgag tccgtcaagctgcagatgtgtgagctcctcagctatctctgcgactgtgagctgcagcac cgagtggaggccattgtggcatttggtgacatttatgtctccaagctgcaggcaaatcag aagttccgctacaatgagctcatgcaggccctgaacatgtctgcggccttgactgcccgg aagaccaaggagttccgctcacccccacaggagcagatcaacatgcttcttaactttcaa ctgggagagaactgcccctgcccagaggagattcgggaggagctgtatgatttccatgag gaccttctccttcactgtggggttcctttggaagaagaggaagaggaggaggaggacacc tcctggacgggaaaactccgtgccttggtttacaaaatcaaaggcccacccaagccagag aaggaacagccaacggaggaggaggagagatgccccacaacattgaaggagctcatctca cagacgatgatctgctgggcccaggaggaccagatccaggatgcagagctggtccgaatg atgttcaacctcctccggaggcagtatgacagcatcggggagctgctacaggcgctgcgg aagacctacaccatcagccatgcctctgtaagcgacaccatcaacctgctggctgccctg ggccagatccgctccctcctcagtgtcaggatgggcaaggaagaggagttgctcatgatc aacgggctgggagaaataatgaacaacaaggtgttttaccagcatcccaacctcatgaga gtcctgggcatgcacgagacggtgatggaggtgatggtcaacgtgttgagtacagagaaa tctcagattgcatttccaaagatggttgctagctgctgccgtttcctttgctatttctgt cgaattagccggcaaaatcagaaggccatgtttgagcacctgagttatcttctggagaat agcagcgttggcctagcctccccgtcgatgaggggatccaccccgctggatgtggcagcg tcctctgtgatggacaacaacgagttagcgctgggcttggaggaaccagacctggagaag gtggtgacctacttggcaggctgtggcctacagagctgccccatgcttctggccaaagga taccctgacgtcggctggaaccccatcgaaggggaacgctacctgtccttcctgaggttt gccgtcttcgtgaacagtgagagtgtggaagaaaatgccagcgttgtggtcaagctgctc atcagacgcccagagtgcttcggcccggccctgcggggcgaggggggaaacggactgttg gcggccatgcagggtgccattaagatctctgagaaccccgcgcttgacctcccctctcaa ggatacaaaagagaagtcagcacggaggccgatgaagaggaagaagaaatcgtgcatatg ggcaatgcaattatgtcattttattctgcccttatagatctactgggccgctgtgctcct gaaatgcacctcatccagacgggaaagggggaggccatccgcatcaggtccatactgcgc tccctggtccccacagaagacctggttgggatcatcagcatccccttgaaactgccctcc cttaacaaagatgggtcggtcagtgagccggatatggcggccaacttctgccctgaccac aaggcacccatggtgctgttcttggaccgcgtctatggcattaaggatcaaacttttctg ctccacttgctggaggttggatttttacctgacctgagagcttctgcctctttagataca gtttccctgagcaccacagaggctgcgcttgcactaaataggtatatatgttctgctgtg ctcccgctcctcacaagatgtgctcctctctttgccggaacagaccactgcacctctctg attgattccacactgcagacgatatacaggctttccaagggacgttccctcaccaaagca caaagggacactatagaagaatgtctgcttgccatttgcaatcacttgaggccttccatg ttacagcagctcctgcgacgcctcgtttttgatgtgccccaactcaatgaatactgcaaa atgcctctcaagcttctgacgaatcactatgaacagtgctggaaatattactgcctgcct tcaggatgggggagctatgggctagctgtggaagaagagctgcacctaacggagaagctt ttctgggggatttttgactctctctcccataagaaatatgacccagatcttttccgaatg gccctgccttgtctcagtgctatagctggggccttgccaccggattatttagataccaga atcacagccactttggagaaacagatctcagtggatgcagatggcaactttgatcccaaa cctatcaacactgtgaatttttccttgcctgaaaaattggaatacatcgtcaccaagtat gctgagcattcacatgataaatgggcctgtgacaagagtcagagcggatggaaatatggg atttccctggatgaaaatgtgaagacccacccactgataaggcctttcaagacattaacg gagaaggagaaggaaatttatcgctggcctgcccgagagtccctgaaaaccatgctagct gtgggctggactgtggagaggaccaaagagggagaagccttggttcaacagcgggaaaat gagaagcttcgaagcgtgtcccaggccaaccagggcaacagctacagccctgctcccctc gacctctcaaacgttgtactctccagagagctccagggaatggtggaggtcgtggctgag aactatcacaatatctgggccaagaagaagaagctggagctggagagcaaaggtggtggc agtcaccctcttctggtaccatatgacaccttgactgccaaagaaaagttcaaggaccgg gagaaggcacaggacctgtttaagttcctccaagtgaatggcgtcatagtttccaggggt atgaaggatatggagctggatgcctcctccatggaaaagaggtttgcctataagttcttg aagaagatcctgaaatacgttgattcggcacaagaatttattgcccatttagaagccatt gtcagcagtgggaaaactgaaaagtctcctcatgaccaggagatcaaattctttgccaaa gttctcctcccgctggttgaccagtacttcaccaatcatcgcctctacttcttgtcatcc cctctgaagcctcttagcagcagcggatacgcctctcataaggagaaagaaatggtggcc agcctgttctgcaaacttgctgcccttgttagacacagaatttccctctttggtagtgat tctactacaatggtgagctgtcttcacatcttagctcagacacttgacacaaggactgtc atgaagtcaggctcggagctggtgaaggctgggttacgagcattctttgaaaatgctgca gaagacttggagaagacgtcagaaaacctgaaacttgggaagttcacccattcccgaacg cagattaaaggcgtttctcagaatattaactatactacagtggccctgctccccatcctg acgtccatctttgagcacgtcgctcagcatcagtttggaatggatctcctcttgggtgat gtgcagatttcctgctaccacatactgtgcagcctctactcccttgggacaggaaagaac atttatgttgaaaggcaacgccctgcccttggagaatgtgtggcctcgctggcagctgcc ataccagtggcattcctggagcccaccctcaatcgctacaatcctctctcggtcttcaac accaaaacccccagggagaggtctattctggggataccagacacggtggaagacatgtgt cctgacatcccccagctggaaggcctgatgaaggaaatcaacgacctggccgagtcaggg gcacggtacacagagatgccgcatgtcatcgaggtgatcttacccatgctctgcaactac ctgtcctactggtgggagcgggggcctgagaacctgccccccagcacagggcagtgctgc accaaggtcacctctgaacacctcagtctcatcctgggcaacattctgaaaatcatcaac aacaacctgggcatcgatgaagcctcctggatgaagcgcatcgcagtgtatgcacagccc atcatcagcaaagccaggcccgacctgctgagaagccacttcatcccaactctggagaag ctgaagaaaaaggctgtcaagaccgtgcaggaggaggagcagttgagagccgatggcaaa ggggacacgcaggaggcggagctcctcatcctggacgaattcgcggtcctctgccgagat ctctatgccttctaccccatgctgatccgctacgtggacaacaacagatctaactggctg aaaagccctgatgctgattctgaccagctcttccgcatggtggcagaagtcttcatcctg tggtgtaaatctcacaacttcaagagggaagagcaaaattttgtgattcagaatgaaatt aataatttggcatttttaactggagacagcaaaagcaagatgtcaaaagccatgcaagta aagtctggaggacaagaccaggagcggaagaagacaaagcggcggggagacttgtattcc atccagacctccctcatcgtggctgcactcaagaaaatgctgcccattggtttgaatatg tgtactccaggcgaccaggagctgatctccctcgcaaaatcgcgatacggccatagggac acagatgaagaggtcagagaacatctgcggaacaacttgcacttgcaggaaaagtctgat gacccagctgtaaaatggcagctgaacctctacaaagatgttctgaagagtgaagaacct ttcaatccagaaaagacagtggagcgtgtgcagagaatttcagcagctgtcttccacctg gaacaggtggaacagcctttgaggtccaagaaggccgtctggcacaaactgctatcaaag caacggaaacgggcagtggtggcctgcttcaggatggcccctctctacaacctgcccagg caccgctctattaacctcttcctccatggctatcagagattttggatagaaacagaggag tattcctttgaagagaaactagtacaggatttggctaaatctccaaaggtggaagaggag gaggaggaagagaccaaaaaacaacctgacccactgcatcagatcattctctattttagc cgcaacgctctcacggagaggagcaaattggaagacgaccctttgtacacctcctattcc agcatgatggctaagagttgtcaaagtggtgaggacgaagaagaagatgaagacaaggaa aaaacattcgaagagaaggagatggagaagcagaaaaccctgtatcagcaagctcggctg catgagcgtggtgccgcggagatggtccttcagatgataagcgctagcaaaggtgagatg agccccatggtggttgagactctgaagctggggatcgccattctgaacggaggcaatgct ggtgtgcaacagaaaatgctagattacctaaaggagaaaaaggatgctggattctttcaa agcctttctggtcttatgcagtcttgcagtgtccttgatttgaatgcatttgagaggcag aataaagctgaaggcctggggatggtgactgaagaaggaacactcattgttcgtgaacgt ggtgaaaaagtactccagaatgacgagttcacgcgtgatctctttagattcctacagtta ctttgtgagggacataacagtgactttcagaacttcctgcggactcagatgggtaacacc accaccgtgaatgtcatcatcagcactgtggactaccttctgcgtctgcaggaatcaatc agtgatttctactggtattattcagggaaggacatcattgatgaatccggacagcacaat ttctccaaagctctggcagtcaccaagcagattttcaattctcttacagaatacatccag ggcccttgcattggtaatcagcagagcctggctcacagcaggctgtgggacgccgtggtt ggcttcctccatgtctttgctaatatgcagatgaaactgtctcaggattccagtcagatc gagctgctgaaggaactcttggatctccttcaggacatggtggtgatgcttctgtccctc ctggaagggaatgtggtaaatggcaccattggcaagcagatggttgacacactggtagaa tcatctaccaatgtagaaatgatcttgaaattctttgacatgttcttgaaacttaaagac ttaaccagctcagacaccttcaaagaatacgacccagatggtaaaggaattatctccaaa agagaattccagaaggccatggaagggcaaaaacagtacacgcagtcagagattgacttt ctcctttcgtgtgcagaagctgatgagaatgacatgtttaattacattgattttgtagac cggttccatgagccggccaaggacatagggtttaatgtggctgtgttattgacaaatctt tctgaacacatgccaaacgattcccggctgaagtgtctgttggacccagcagaaagtgtg ctaaattacttcgaaccctacctaggacgcatcgagatcatgggtggggccaagaaaatt gagcgtgtttattttgaaatcagtgagtccagtcgcactcagtgggagaagccccaggtg aaggaatctaagcgacagttcatttttgatgttgtcaacgaaggtggggagcaggaaaag atggagctgtttgtgaacttctgtgaggacaccatctttgaaatgcagttagcatctcag atctctgaatccgattcagcggacaggccagaagaggaggaagaagatgaagattcttct tacgtgttagaaattgcgggtgaagaggaggaagacgggtctttcgagccggcctctgca tttgcaatggcctgtgcctctgtgaagaggaacgtcgccgactttctgaagagggcaacc ctgaagaacctcaggaagcagtacaggaacgtgaaaaagatgactgcgaaggagctggtg aaggtgctctgctcctttttctggatgctgttcctggggctgttccagatgctcttcacc atcctgggaggaatctttcagatcctctggagcacagtgttcggagggggcctggtagaa ggggcaaagaacatcagagtgaccaagatcctgggtgacatgcctgacccaacccaattt ggtatccatgatgacactatggaggctgagagggcagaggtgatggagccaggtatcacc actgaactagtacacttcataaagggggagaagggagatacagatatcatgtcagacctc tttggactccacccaaagaaagagggcagcttaaagcatgggcctgaagtgggtttgggt gacctctcagaaattattggcaaggatgaaccccctacgttagagagtactgtacagaag aagaggaaagctcaggcagcagagatgaaagcagcaaatgaagcagaaggaaaagtagaa tccgagaaggcagacatggaagatggagagaaggaagacaaagacaaagaagaggagcaa gccgagcacctgtggacagaagtgacaaaaaagaagaagcggcggtgtggtcagaaggct gagaagccggaagctttcacagccaatttctttaaagggctggacatctatcagaccaag ttactgcattacctggccaggaatttctacaacctgaggttccttgctctgtttgtagcc ttcgctatcaacttcatcctgcttttttataaggtcactgaagaacctttagaagaagag acagaggatgttgcaaacctatggaattcatttaatgacgaggaagaggaagaagcgatg gtgttctttgtccttcaggagagcactgggtatatggcaccaacgctgcgggccctggcc atcatccacaccatcatctctctagtctgtgtggtgggctactactgcctgaaggtgcct ttggtggtattcaaaagggaaaaagaaatcgccaggaagctggagtttgatggcctatat atcaccgaacagccatctgaagatgacatcaaggggcaatgggaccgcttggtgatcaac acaccatcttttcctaataactactgggacaagtttgtaaagagaaaggtgatcaacaag tatggagatctctacggagcagagcgcattgctgaacttctgggtttggacaaaaatgct cttgacttcagcccagtagaagagaccaaagcagaggcggcttctctggtgtcatggcta agttccatagacatgaagtaccatatctggaagcttggagttgtgtttactgacaactcc tttctctaccttgcctggtatacaaccatgtcagtcctgggccactacaataacttcttc tttgctgctcacctgctggatatcgcaatgggcttcaagacactgaggaccattctgtca tctgtaactcacaatggcaaacagttggttctgacggttggtctcctggccgtggtggtg tatctctatactgtggtggctttcaacttcttccgcaagttctacaacaaaagtgaagac gatgacgagcctgatatgaagtgtgacgacatgatgacgtgttaccttttccacatgtac gtgggagtgagagcaggaggtggcattggtgacgagattgaagaccctgctggtgatcct tatgaaatgtatcgcattgtctttgacattacctttttcttctttgtcattgtcatcttg ctggccatcattcaaggtcttattattgatgctttcggagagctaagagaccagcaggaa caagtgcgagaagatatggagaccaaatgtttcatctgtgggattggcaatgactacttt gacacgacccctcatggttttgaaacacatacattacaagagcacaacttagccaactac ttgttcttcctgatgtatttgattaataaagatgaaacagagcacacgggtcaggaatct tatgtctggaagatgtaccaagaaaggtgctgggatttcttcccagccggtgactgcttt cgtaaacagtatgaagatcagcttggataa

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