KEGG   Papio anubis (olive baboon): 101016532
Entry
101016532         CDS       T07474                                 
Symbol
PRKCA
Name
(RefSeq) protein kinase C alpha type isoform X4
  KO
K02677  classical protein kinase C alpha type [EC:2.7.11.13]
Organism
panu  Papio anubis (olive baboon)
Pathway
panu01521  EGFR tyrosine kinase inhibitor resistance
panu04010  MAPK signaling pathway
panu04012  ErbB signaling pathway
panu04014  Ras signaling pathway
panu04015  Rap1 signaling pathway
panu04020  Calcium signaling pathway
panu04066  HIF-1 signaling pathway
panu04070  Phosphatidylinositol signaling system
panu04071  Sphingolipid signaling pathway
panu04072  Phospholipase D signaling pathway
panu04082  Neuroactive ligand signaling
panu04150  mTOR signaling pathway
panu04151  PI3K-Akt signaling pathway
panu04261  Adrenergic signaling in cardiomyocytes
panu04270  Vascular smooth muscle contraction
panu04310  Wnt signaling pathway
panu04360  Axon guidance
panu04370  VEGF signaling pathway
panu04510  Focal adhesion
panu04540  Gap junction
panu04613  Neutrophil extracellular trap formation
panu04650  Natural killer cell mediated cytotoxicity
panu04664  Fc epsilon RI signaling pathway
panu04666  Fc gamma R-mediated phagocytosis
panu04670  Leukocyte transendothelial migration
panu04713  Circadian entrainment
panu04720  Long-term potentiation
panu04723  Retrograde endocannabinoid signaling
panu04724  Glutamatergic synapse
panu04725  Cholinergic synapse
panu04726  Serotonergic synapse
panu04727  GABAergic synapse
panu04728  Dopaminergic synapse
panu04730  Long-term depression
panu04750  Inflammatory mediator regulation of TRP channels
panu04911  Insulin secretion
panu04912  GnRH signaling pathway
panu04916  Melanogenesis
panu04918  Thyroid hormone synthesis
panu04919  Thyroid hormone signaling pathway
panu04921  Oxytocin signaling pathway
panu04925  Aldosterone synthesis and secretion
panu04926  Relaxin signaling pathway
panu04928  Parathyroid hormone synthesis, secretion and action
panu04929  GnRH secretion
panu04933  AGE-RAGE signaling pathway in diabetic complications
panu04935  Growth hormone synthesis, secretion and action
panu04960  Aldosterone-regulated sodium reabsorption
panu04961  Endocrine and other factor-regulated calcium reabsorption
panu04970  Salivary secretion
panu04971  Gastric acid secretion
panu04972  Pancreatic secretion
panu05017  Spinocerebellar ataxia
panu05022  Pathways of neurodegeneration - multiple diseases
panu05031  Amphetamine addiction
panu05032  Morphine addiction
panu05143  African trypanosomiasis
panu05146  Amoebiasis
panu05161  Hepatitis B
panu05163  Human cytomegalovirus infection
panu05164  Influenza A
panu05170  Human immunodeficiency virus 1 infection
panu05171  Coronavirus disease - COVID-19
panu05200  Pathways in cancer
panu05205  Proteoglycans in cancer
panu05206  MicroRNAs in cancer
panu05207  Chemical carcinogenesis - receptor activation
panu05214  Glioma
panu05223  Non-small cell lung cancer
panu05225  Hepatocellular carcinoma
panu05231  Choline metabolism in cancer
panu05415  Diabetic cardiomyopathy
panu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:panu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101016532 (PRKCA)
   04012 ErbB signaling pathway
    101016532 (PRKCA)
   04014 Ras signaling pathway
    101016532 (PRKCA)
   04015 Rap1 signaling pathway
    101016532 (PRKCA)
   04310 Wnt signaling pathway
    101016532 (PRKCA)
   04370 VEGF signaling pathway
    101016532 (PRKCA)
   04066 HIF-1 signaling pathway
    101016532 (PRKCA)
   04020 Calcium signaling pathway
    101016532 (PRKCA)
   04070 Phosphatidylinositol signaling system
    101016532 (PRKCA)
   04072 Phospholipase D signaling pathway
    101016532 (PRKCA)
   04071 Sphingolipid signaling pathway
    101016532 (PRKCA)
   04151 PI3K-Akt signaling pathway
    101016532 (PRKCA)
   04150 mTOR signaling pathway
    101016532 (PRKCA)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    101016532 (PRKCA)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101016532 (PRKCA)
   04540 Gap junction
    101016532 (PRKCA)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    101016532 (PRKCA)
   04650 Natural killer cell mediated cytotoxicity
    101016532 (PRKCA)
   04664 Fc epsilon RI signaling pathway
    101016532 (PRKCA)
   04666 Fc gamma R-mediated phagocytosis
    101016532 (PRKCA)
   04670 Leukocyte transendothelial migration
    101016532 (PRKCA)
  09152 Endocrine system
   04911 Insulin secretion
    101016532 (PRKCA)
   04929 GnRH secretion
    101016532 (PRKCA)
   04912 GnRH signaling pathway
    101016532 (PRKCA)
   04921 Oxytocin signaling pathway
    101016532 (PRKCA)
   04926 Relaxin signaling pathway
    101016532 (PRKCA)
   04935 Growth hormone synthesis, secretion and action
    101016532 (PRKCA)
   04918 Thyroid hormone synthesis
    101016532 (PRKCA)
   04919 Thyroid hormone signaling pathway
    101016532 (PRKCA)
   04928 Parathyroid hormone synthesis, secretion and action
    101016532 (PRKCA)
   04916 Melanogenesis
    101016532 (PRKCA)
   04925 Aldosterone synthesis and secretion
    101016532 (PRKCA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101016532 (PRKCA)
   04270 Vascular smooth muscle contraction
    101016532 (PRKCA)
  09154 Digestive system
   04970 Salivary secretion
    101016532 (PRKCA)
   04971 Gastric acid secretion
    101016532 (PRKCA)
   04972 Pancreatic secretion
    101016532 (PRKCA)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    101016532 (PRKCA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    101016532 (PRKCA)
  09156 Nervous system
   04724 Glutamatergic synapse
    101016532 (PRKCA)
   04727 GABAergic synapse
    101016532 (PRKCA)
   04725 Cholinergic synapse
    101016532 (PRKCA)
   04728 Dopaminergic synapse
    101016532 (PRKCA)
   04726 Serotonergic synapse
    101016532 (PRKCA)
   04720 Long-term potentiation
    101016532 (PRKCA)
   04730 Long-term depression
    101016532 (PRKCA)
   04723 Retrograde endocannabinoid signaling
    101016532 (PRKCA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101016532 (PRKCA)
  09158 Development and regeneration
   04360 Axon guidance
    101016532 (PRKCA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    101016532 (PRKCA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101016532 (PRKCA)
   05206 MicroRNAs in cancer
    101016532 (PRKCA)
   05205 Proteoglycans in cancer
    101016532 (PRKCA)
   05207 Chemical carcinogenesis - receptor activation
    101016532 (PRKCA)
   05231 Choline metabolism in cancer
    101016532 (PRKCA)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101016532 (PRKCA)
   05214 Glioma
    101016532 (PRKCA)
   05223 Non-small cell lung cancer
    101016532 (PRKCA)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101016532 (PRKCA)
   05161 Hepatitis B
    101016532 (PRKCA)
   05171 Coronavirus disease - COVID-19
    101016532 (PRKCA)
   05164 Influenza A
    101016532 (PRKCA)
   05163 Human cytomegalovirus infection
    101016532 (PRKCA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    101016532 (PRKCA)
   05143 African trypanosomiasis
    101016532 (PRKCA)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    101016532 (PRKCA)
   05022 Pathways of neurodegeneration - multiple diseases
    101016532 (PRKCA)
  09165 Substance dependence
   05031 Amphetamine addiction
    101016532 (PRKCA)
   05032 Morphine addiction
    101016532 (PRKCA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101016532 (PRKCA)
   05415 Diabetic cardiomyopathy
    101016532 (PRKCA)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    101016532 (PRKCA)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101016532 (PRKCA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:panu01001]
    101016532 (PRKCA)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:panu04131]
    101016532 (PRKCA)
Enzymes [BR:panu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     101016532 (PRKCA)
Protein kinases [BR:panu01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   101016532 (PRKCA)
Membrane trafficking [BR:panu04131]
 Endocytosis
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    101016532 (PRKCA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C2 Pkinase_C ABC1 Kinase-like
Other DBs
NCBI-GeneID: 101016532
NCBI-ProteinID: XP_009189319
Ensembl: ENSPANG00000020564
LinkDB
Position
17:58289136..58791910
AA seq 552 aa
MNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVADEKLHVTVRDAKNLIPMDPNGLSDPYV
KLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFM
GSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNMELRQKFEKAKLGPAGNK
VISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVI
QDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFK
EPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTR
TFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVS
YPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKP
KVTLCTKMHWLQWASRSSCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVN
PQFVHPILQSAV
NT seq 1659 nt   +upstreamnt  +downstreamnt
atgaacgttcacaagcaatgcgtcatcaatgtccccagcctctgcggaatggatcacaca
gagaagagggggcggatttacctaaaggctgaggttgctgatgaaaagctccatgtcaca
gtacgagatgcaaaaaatctaatccctatggatccaaacgggctttcagatccttatgtg
aagctgaaacttattcctgatcccaagaatgaaagcaaacaaaaaaccaaaaccatccgc
tccacactaaatccccagtggaatgagtcctttacattcaaattgaaaccttcagacaaa
gaccgacgactgtctgtagaaatctgggactgggatcgaacaacaaggaatgacttcatg
ggatccctttcctttggggtttcggagctaatgaagatgccagccagtggatggtacaag
ttgcttaaccaagaagaaggtgagtactacaatgtacccattccagaaggggacgaagaa
ggaaacatggaactcaggcagaaattcgagaaagccaagcttggccctgctggcaacaaa
gtcatcagtccctctgaagacaggaaacaaccttccaacaacctggaccgagtgaaactc
accgacttcaatttcctcatggtgctggggaaggggagttttggaaaggtgatgcttgcc
gacaggaagggcacagaagaactgtatgcaatcaaaatcctgaagaaggatgtggtgatt
caggatgacgacgtggagtgcaccatggtagaaaaacgagtcttggccctgcttgacaaa
cccccgttcttgacgcagctgcactcctgcttccagacagtggatcggctgtacttcgtc
atggaatatgtcaacggtggggacctcatgtaccacattcagcaagtaggaaaatttaag
gaaccacaagcagtattctatgcggcagagatttccatcggattgttctttcttcataaa
agaggaatcatttatagggatctgaagttagataacgtcatgttggattcagaaggacat
atcaaaattgctgacttcgggatgtgcaaggaacacatgatggatggagtcacgaccagg
accttctgtgggactccagattacattgccccagagattatcgcttatcagccatatgga
aaatctgtggactggtgggcctatggcgtcctgttgtatgaaatgcttgccgggcagcct
ccattcgatggtgaagatgaggacgagctatttcagtctatcatggagcacaacgtttcc
tatccaaaatccttgtccaaggaggctgtttccatctgcaaaggactgatgaccaaacac
ccagccaagcggctgggctgcgggcctgagggggagagggacgtgagagaacatgctttc
ttccggaggatcgactgggaaaaactggagaacagggagatccagccaccattcaagccc
aaagtgactttgtgtaccaaaatgcactggcttcagtgggcttccaggtcttcgtgcggc
aaaggagcagaaaactttgacaagttcttcacacgagggcagcccgtcttaacaccacct
gatcagctggttattgctaacatagaccagtctgattttgaagggttctcgtatgtcaac
ccccagtttgtgcaccccatcttacagagtgcagtatga

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