KEGG   Papio anubis (olive baboon): 101019884
Entry
101019884         CDS       T07474                                 
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
panu  Papio anubis (olive baboon)
Pathway
panu01522  Endocrine resistance
panu04010  MAPK signaling pathway
panu04012  ErbB signaling pathway
panu04014  Ras signaling pathway
panu04024  cAMP signaling pathway
panu04068  FoxO signaling pathway
panu04071  Sphingolipid signaling pathway
panu04137  Mitophagy - animal
panu04140  Autophagy - animal
panu04141  Protein processing in endoplasmic reticulum
panu04210  Apoptosis
panu04215  Apoptosis - multiple species
panu04217  Necroptosis
panu04310  Wnt signaling pathway
panu04380  Osteoclast differentiation
panu04510  Focal adhesion
panu04530  Tight junction
panu04620  Toll-like receptor signaling pathway
panu04621  NOD-like receptor signaling pathway
panu04622  RIG-I-like receptor signaling pathway
panu04625  C-type lectin receptor signaling pathway
panu04657  IL-17 signaling pathway
panu04658  Th1 and Th2 cell differentiation
panu04659  Th17 cell differentiation
panu04660  T cell receptor signaling pathway
panu04664  Fc epsilon RI signaling pathway
panu04668  TNF signaling pathway
panu04722  Neurotrophin signaling pathway
panu04723  Retrograde endocannabinoid signaling
panu04728  Dopaminergic synapse
panu04750  Inflammatory mediator regulation of TRP channels
panu04910  Insulin signaling pathway
panu04912  GnRH signaling pathway
panu04914  Progesterone-mediated oocyte maturation
panu04917  Prolactin signaling pathway
panu04920  Adipocytokine signaling pathway
panu04926  Relaxin signaling pathway
panu04930  Type II diabetes mellitus
panu04931  Insulin resistance
panu04932  Non-alcoholic fatty liver disease
panu04933  AGE-RAGE signaling pathway in diabetic complications
panu04935  Growth hormone synthesis, secretion and action
panu04936  Alcoholic liver disease
panu05010  Alzheimer disease
panu05012  Parkinson disease
panu05016  Huntington disease
panu05017  Spinocerebellar ataxia
panu05020  Prion disease
panu05022  Pathways of neurodegeneration - multiple diseases
panu05132  Salmonella infection
panu05133  Pertussis
panu05135  Yersinia infection
panu05142  Chagas disease
panu05145  Toxoplasmosis
panu05152  Tuberculosis
panu05161  Hepatitis B
panu05162  Measles
panu05166  Human T-cell leukemia virus 1 infection
panu05167  Kaposi sarcoma-associated herpesvirus infection
panu05169  Epstein-Barr virus infection
panu05170  Human immunodeficiency virus 1 infection
panu05171  Coronavirus disease - COVID-19
panu05200  Pathways in cancer
panu05208  Chemical carcinogenesis - reactive oxygen species
panu05210  Colorectal cancer
panu05212  Pancreatic cancer
panu05231  Choline metabolism in cancer
panu05415  Diabetic cardiomyopathy
panu05417  Lipid and atherosclerosis
panu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:panu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    101019884 (MAPK8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101019884 (MAPK8)
   04012 ErbB signaling pathway
    101019884 (MAPK8)
   04014 Ras signaling pathway
    101019884 (MAPK8)
   04310 Wnt signaling pathway
    101019884 (MAPK8)
   04668 TNF signaling pathway
    101019884 (MAPK8)
   04068 FoxO signaling pathway
    101019884 (MAPK8)
   04071 Sphingolipid signaling pathway
    101019884 (MAPK8)
   04024 cAMP signaling pathway
    101019884 (MAPK8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101019884 (MAPK8)
   04137 Mitophagy - animal
    101019884 (MAPK8)
  09143 Cell growth and death
   04210 Apoptosis
    101019884 (MAPK8)
   04215 Apoptosis - multiple species
    101019884 (MAPK8)
   04217 Necroptosis
    101019884 (MAPK8)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101019884 (MAPK8)
   04530 Tight junction
    101019884 (MAPK8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101019884 (MAPK8)
   04621 NOD-like receptor signaling pathway
    101019884 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    101019884 (MAPK8)
   04625 C-type lectin receptor signaling pathway
    101019884 (MAPK8)
   04660 T cell receptor signaling pathway
    101019884 (MAPK8)
   04658 Th1 and Th2 cell differentiation
    101019884 (MAPK8)
   04659 Th17 cell differentiation
    101019884 (MAPK8)
   04657 IL-17 signaling pathway
    101019884 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    101019884 (MAPK8)
  09152 Endocrine system
   04910 Insulin signaling pathway
    101019884 (MAPK8)
   04920 Adipocytokine signaling pathway
    101019884 (MAPK8)
   04912 GnRH signaling pathway
    101019884 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    101019884 (MAPK8)
   04917 Prolactin signaling pathway
    101019884 (MAPK8)
   04926 Relaxin signaling pathway
    101019884 (MAPK8)
   04935 Growth hormone synthesis, secretion and action
    101019884 (MAPK8)
  09156 Nervous system
   04728 Dopaminergic synapse
    101019884 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    101019884 (MAPK8)
   04722 Neurotrophin signaling pathway
    101019884 (MAPK8)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101019884 (MAPK8)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101019884 (MAPK8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101019884 (MAPK8)
   05208 Chemical carcinogenesis - reactive oxygen species
    101019884 (MAPK8)
   05231 Choline metabolism in cancer
    101019884 (MAPK8)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101019884 (MAPK8)
   05212 Pancreatic cancer
    101019884 (MAPK8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101019884 (MAPK8)
   05170 Human immunodeficiency virus 1 infection
    101019884 (MAPK8)
   05161 Hepatitis B
    101019884 (MAPK8)
   05171 Coronavirus disease - COVID-19
    101019884 (MAPK8)
   05162 Measles
    101019884 (MAPK8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101019884 (MAPK8)
   05169 Epstein-Barr virus infection
    101019884 (MAPK8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101019884 (MAPK8)
   05135 Yersinia infection
    101019884 (MAPK8)
   05133 Pertussis
    101019884 (MAPK8)
   05152 Tuberculosis
    101019884 (MAPK8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101019884 (MAPK8)
   05142 Chagas disease
    101019884 (MAPK8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101019884 (MAPK8)
   05012 Parkinson disease
    101019884 (MAPK8)
   05016 Huntington disease
    101019884 (MAPK8)
   05017 Spinocerebellar ataxia
    101019884 (MAPK8)
   05020 Prion disease
    101019884 (MAPK8)
   05022 Pathways of neurodegeneration - multiple diseases
    101019884 (MAPK8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101019884 (MAPK8)
   05418 Fluid shear stress and atherosclerosis
    101019884 (MAPK8)
   05415 Diabetic cardiomyopathy
    101019884 (MAPK8)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    101019884 (MAPK8)
   04936 Alcoholic liver disease
    101019884 (MAPK8)
   04932 Non-alcoholic fatty liver disease
    101019884 (MAPK8)
   04931 Insulin resistance
    101019884 (MAPK8)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101019884 (MAPK8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101019884 (MAPK8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:panu01001]
    101019884 (MAPK8)
Enzymes [BR:panu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     101019884 (MAPK8)
Protein kinases [BR:panu01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   101019884 (MAPK8)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like FTA2 APH DUF530
Other DBs
NCBI-GeneID: 101019884
NCBI-ProteinID: XP_017818292
Ensembl: ENSPANG00000022627
UniProt: A0A2I3MLZ7
LinkDB
Position
11:85007424..85143214
AA seq 427 aa
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq 1284 nt   +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacaacaatttttatagtgtagagattggagattctacattc
acagtcctgaaacggtatcagaatttaaaacctataggctcaggagcgcaaggaatagta
tgcgcagcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagccgacca
tttcagaatcagactcatgccaagcgggcctacagagagctagttcttatgaaatgtgtt
aatcacaaaaatataattggccttttgaatgttttcacaccacagaaatccctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgcaaatctttgccaagtgattcag
atggaactagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaag
caccttcactctgctggaattattcatcgggacttaaagcccagtaatatagtagtaaaa
tctgactgcactttgaagattcttgacttcggtctggccaggactgcaggaacgagtttt
atgatgacgccttacgtagtgactcgctactacagagcacccgaggtcatccttggcatg
ggctacaaggaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacag
cttggaacaccatgtcctgaattcatgaagaaactgcaaccaacagtaaggacttatgtt
gaaaacagacctaaatatgctggatatagcttcgagaaactcttccctgatgtacttttc
ccagctgactcggaacacaacaaacttaaagccagtcaggcaagggatttgttatccaaa
atgctggtaatagatgcatctaaaaggatctctgtagatgaagctctccaacacccgtac
atcaatgtctggtatgatccttctgaagcagaagctccgccaccaaagatccctgacaag
cagttagatgaaagggaacacacaatagaagagtggaaagaattgatatataaggaagtt
atggacttggaggagagaaccaagaatggagttatacgggggcagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcgtcatcgtcgtctgtcaatgatgtgtct
tcaatgtcaacagatccgactttggcctcggatacagacagcagtctagaagcatcagct
gggcctctgggctgctgtagatga

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