Pseudomonas paraeruginosa PA7: PSPA7_4988
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Entry
PSPA7_4988 CDS
T00569
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
pap
Pseudomonas paraeruginosa PA7
Pathway
pap00300
Lysine biosynthesis
pap00550
Peptidoglycan biosynthesis
pap01100
Metabolic pathways
pap01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
pap00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
PSPA7_4988 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
PSPA7_4988 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
PSPA7_4988 (murF)
Enzymes [BR:
pap01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
PSPA7_4988 (murF)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ABR85876
UniProt:
A6VB89
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Position
complement(5144746..5146122)
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AA seq
458 aa
AA seq
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MLEPLRLSQLTVALDARLIGEDAVFSAVSTDSRAIGPGQLFIALSGPRFDGHDYLAEVAA
KGAVAALVEREVADAPLPQLLVRDTRAALGRLGALNRRKFTGPLAAMTGSSGKTTVKEML
ASILRTQAGDAESVLATRGNLNNDLGVPLTLLQLAPQHRSAVIELGASRIGEIAYTVGLT
RPHVAIITNAGTAHVGEFGGPEKIVEAKGEILEGLAADGTAVLNLDDKAFATWKARANGR
PLLTFSLEQAQADFHAADLQRDARGCMGFRLHGVAGEAQVQLNLLGRHNVANALAAAAAA
HALGVPLDGIVAGLQALQPVKGRAVAQLTASGLRVIDDSYNANPASMLAAIDILGGFSGR
TVLVLGDMGELGSWAEQAHREVGAYAAGKVSALYAVGPLMANAVQAFGEAGRHFADQASL
IRALATEQPTTTILIKGSRSAAMDKVVAALCGSSEESH
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgcttgagcctcttcgcctcagccagttgacggtcgcgctggacgcccgcctgatcggc
gaggacgccgtcttttcggcggtttccaccgacagtcgcgccatcgggcccggccaactg
ttcattgccctgagtgggccgcgtttcgacggccacgactatctcgccgaggttgccgcc
aagggcgcggtggctgcgctggtggagcgcgaagtcgccgacgcgcccctgccgcaattg
ctggtgcgcgatacccgtgcggccctggggcgactgggcgcgctgaaccggcgcaagttc
accggtccgctggcggccatgacgggctccagcggcaagaccacggtcaaggagatgctc
gccagcatcctgcgtacccaggccggcgacgccgagtcggtgctggcgacccgtggcaat
ctgaacaacgacctcggcgtaccgctgaccctgctgcaactggcgccgcagcaccgtagc
gcagtgatcgaactgggcgcctcgcgcatcggcgagatcgcctatacggtcggactgacc
cgcccgcacgtggcgatcatcaccaatgccgggaccgcccatgtcggcgagttcggcggg
ccggagaagatcgtcgaggccaagggcgagatcctcgaaggcctggccgccgacggcacc
gcggtgctgaatctggacgacaaggccttcgccacctggaaggcgcgggccaacgggcgt
ccgctgctgaccttctccctcgagcaggcccaggccgacttccatgccgccgatctgcag
cgcgacgcgcgtggctgcatgggcttccggctgcacggcgtagcgggcgaggcacaggtc
cagctcaatctcctgggccggcataacgtggccaatgcgctggccgccgctgccgcggcc
catgcgctgggcgtgccgctggacgggatcgtcgccgggctgcaggcgctgcaaccggtc
aagggccgcgcggtagcgcagctgactgccagcgggctgcgtgtgatagacgacagctac
aacgccaaccccgcgtcaatgctggcggcgattgatatactgggcggcttttccgggcgc
accgtcctggtcctcggagacatgggcgaactcggttcctgggccgagcaggcccaccgc
gaggtgggcgcctacgccgccggcaaggtatccgcgctgtacgcggtcgggccactgatg
gccaacgccgtgcaggcgttcggcgaggcgggccggcatttcgccgaccaggccagcctg
atccgggcgctggccaccgaacaaccgacaaccaccattctgatcaagggttcccgcagc
gcggcgatggacaaagtcgtcgcggcgctgtgcggttcctccgaggagagtcactaa
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