Proteus appendicitidis: QQS39_12610
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Entry
QQS39_12610 CDS
T09947
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
papp
Proteus appendicitidis
Pathway
papp00790
Folate biosynthesis
papp01100
Metabolic pathways
papp01240
Biosynthesis of cofactors
Module
papp_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
papp00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
QQS39_12610 (folC)
Enzymes [BR:
papp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
QQS39_12610 (folC)
6.3.2.17 tetrahydrofolate synthase
QQS39_12610 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
WIV87311
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Position
complement(2676543..2677841)
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AA seq
432 aa
AA seq
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MSNIITAPKATSPLSVWLSYLEHLHSSAIDMGLERVGKVGKILNVLRPAPKVITVSGTNG
KGTTCHMLESILMASGLKVGVYSSPHLVRYTERVRIQGKELAEDAFCDVFAEIEQARGDI
SLTFFEYGTLAALKLFQQAQLDVVILEVGLGGRLDATNIVDADIAAITSIALDHTDWLGA
DREHIGHEKAGIFRANHYAVVGEPDMPHSIAQVANEKHAKLFRRGTDWSFVIEGDHWQWR
CADCEFDALPIPNIPLANAATAMGVIRCLLKSDDKVSQAITQQSIVEGMSRAQLPGRFQV
ISQHPLVIFDVAHNPHAAGYLAEKLSQLPQKSDTQVRIVVGMLGDKDIAGTLACLTPLTD
HWYVAPLNEFRGASADVLAQHLEKPMVFDSVEKAWQQAMSDAAPNDIVVVCGSFHTVAHV
MELLEKESVGGK
NT seq
1299 nt
NT seq
+upstream
nt +downstream
nt
atgtctaatatcataactgctcctaaagccacatcgcctttgtcggtgtggctttcttat
cttgaacatttacactctagtgccattgatatggggttagagcgagtcggcaaggtagga
aaaatattaaacgtgttacgtcctgcgccgaaggtaatcactgtctcaggcacgaatgga
aaaggcacaacctgtcatatgctagagtcaatcttgatggcatcaggattgaaagtcggc
gtttatagctctcctcatcttgttcgttatacagaacgcgttcgtatccaaggcaaagaa
ctcgctgaagatgctttttgtgacgtttttgctgaaattgaacaagctagaggcgatatc
tcgctaaccttttttgaatacggcactttggctgcgctgaagttatttcaacaagcacaa
cttgatgttgttattcttgaagtaggattaggcggtcggttagatgcgacgaatatcgtt
gatgcagatattgctgctatcacaagtattgccctcgatcatactgattggttaggtgca
gatagagagcatattggtcacgagaaagccggtattttccgagccaatcactatgctgtt
gtgggcgagccggatatgcctcattccattgcacaagtagccaatgaaaaacacgccaag
ctttttcgtcgtggaacagattggtcttttgttattgaaggcgatcactggcagtggcgt
tgtgctgactgtgaatttgatgcgttgccaatccctaatattccgctagccaatgcggcg
acagcgatgggtgttattcgttgcttgcttaaatctgatgataaagtcagtcaagcaatc
acacagcaaagcattgttgaaggtatgtctcgtgctcaattaccgggtcgttttcaggta
atttctcaacatcctttggttatctttgatgtggcacataatcctcatgcagcaggatat
ttagcggaaaaattatcacaattaccacaaaaatctgatactcaagtgcgtattgttgtt
ggtatgctgggtgataaagatatagcaggaacattagcgtgcttaacgccattgactgat
cattggtatgtcgctccacttaatgagtttcgtggtgcttctgcggatgtgttagctcag
catcttgagaaaccaatggtattcgatagtgttgaaaaggcatggcaacaagcaatgtct
gatgctgctcctaacgatatcgttgtggtttgtggctcatttcatactgtcgcgcatgtg
atggaacttttggaaaaggagagtgtgggtggcaagtaa
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