KEGG   PATHWAY: bvi02030
Entry
bvi02030                    Pathway                                
Name
Bacterial chemotaxis - Burkholderia vietnamiensis G4
Description
Chemotaxis is the process by which cells sense chemical gradients in their environment and then move towards more favorable conditions. In chemotaxis, events at the receptors control autophosphorylation of the CheA histidine kinase, and the phosphohistidine is the substrate for the response regulator CheY, which catalyzes the transfer of the phosphoryl group to a conserved aspartate. The resulting CheY-P can interact with the switch mechanism in the motor. This interaction causes a change in behavior, such as in direction or speed of rotation of flagella.
Class
Cellular Processes; Cell motility
Pathway map
bvi02030  Bacterial chemotaxis
bvi02030

Other DBs
GO: 0006935
Organism
Burkholderia vietnamiensis G4 [GN:bvi]
Gene
Bcep1808_5311  methyl-accepting chemotaxis sensory transducer [KO:K03406]
Bcep1808_5173  methyl-accepting chemotaxis sensory transducer [KO:K03406]
Bcep1808_4849  methyl-accepting chemotaxis sensory transducer [KO:K03406]
Bcep1808_1407  methyl-accepting chemotaxis sensory transducer [KO:K03406]
Bcep1808_2934  methyl-accepting chemotaxis sensory transducer [KO:K03406]
Bcep1808_4764  methyl-accepting chemotaxis sensory transducer [KO:K03406]
Bcep1808_4905  methyl-accepting chemotaxis sensory transducer [KO:K03406]
Bcep1808_5457  methyl-accepting chemotaxis sensory transducer [KO:K03406]
Bcep1808_4374  methyl-accepting chemotaxis sensory transducer [KO:K03406]
Bcep1808_4309  methyl-accepting chemotaxis sensory transducer [KO:K03406]
Bcep1808_6423  methyl-accepting chemotaxis sensory transducer [KO:K03406]
Bcep1808_6424  methyl-accepting chemotaxis sensory transducer [KO:K03406]
Bcep1808_5670  methyl-accepting chemotaxis sensory transducer [KO:K03406]
Bcep1808_0217  methyl-accepting chemotaxis sensory transducer [KO:K05874]
Bcep1808_1563  methyl-accepting chemotaxis sensory transducer [KO:K05874]
Bcep1808_3672  methyl-accepting chemotaxis sensory transducer [KO:K05874]
Bcep1808_5192  methyl-accepting chemotaxis sensory transducer [KO:K05874]
Bcep1808_4077  methyl-accepting chemotaxis sensory transducer [KO:K05874]
Bcep1808_6282  methyl-accepting chemotaxis sensory transducer [KO:K05874]
Bcep1808_3592  methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor [KO:K03776]
Bcep1808_3591  methyl-accepting chemotaxis sensory transducer [KO:K03776]
Bcep1808_1506  monosaccharide ABC transporter substrate-binding protein, CUT2 family [KO:K10439]
Bcep1808_1558  monosaccharide ABC transporter substrate-binding protein, CUT2 family [KO:K10439]
Bcep1808_3380  monosaccharide ABC transporter substrate-binding protein, CUT2 family [KO:K10439]
Bcep1808_3130  extracellular solute-binding protein, family 5 [KO:K12368]
Bcep1808_3018  extracellular solute-binding protein, family 5 [KO:K12368]
Bcep1808_0215  CheA signal transduction histidine kinase [KO:K03407] [EC:2.7.13.3]
Bcep1808_4637  putative CheA signal transduction histidine kinase [KO:K03407] [EC:2.7.13.3]
Bcep1808_0216  CheW protein [KO:K03408]
Bcep1808_5671  putative CheW protein [KO:K03408]
Bcep1808_0221  response regulator receiver protein [KO:K03413]
Bcep1808_0214  response regulator receiver protein [KO:K03413]
Bcep1808_4641  response regulator receiver protein [KO:K03413]
Bcep1808_6983  response regulator receiver protein [KO:K03413]
Bcep1808_3802  CheC, inhibitor of MCP methylation [KO:K03410]
Bcep1808_0222  chemotaxis phosphatase, CheZ [KO:K03414]
Bcep1808_0220  response regulator receiver modulated CheB methylesterase [KO:K03412] [EC:3.1.1.61 3.5.1.44]
Bcep1808_0219  CheD [KO:K03411] [EC:3.5.1.44]
Bcep1808_0218  MCP methyltransferase, CheR-type [KO:K00575] [EC:2.1.1.80]
Bcep1808_3150  flagellar motor switch protein FliG [KO:K02410]
Bcep1808_0050  flagellar motor switch protein FliM [KO:K02416]
Bcep1808_0049  flagellar motor switch protein FliN [KO:K02417]
Bcep1808_4140  MotA/TolQ/ExbB proton channel [KO:K02556]
Bcep1808_0212  chemotaxis MotA protein [KO:K02556]
Bcep1808_0213  OmpA/MotB domain protein [KO:K02557]
Bcep1808_4141  OmpA/MotB domain protein [KO:K02557]
Compound
C00049  L-Aspartate
C00107  Dipeptide
C00121  D-Ribose
C00124  D-Galactose
C00208  Maltose
C00716  Serine
Reference
  Authors
Kristich CJ, Ordal GW.
  Title
Bacillus subtilis CheD is a chemoreceptor modification enzyme required for chemotaxis.
  Journal
J Biol Chem 277:25356-62 (2002)
DOI:10.1074/jbc.M201334200
Reference
  Authors
Kirby JR, Kristich CJ, Saulmon MM, Zimmer MA, Garrity LF, Zhulin IB, Ordal GW.
  Title
CheC is related to the family of flagellar switch proteins and acts independently from CheD to control chemotaxis in Bacillus subtilis.
  Journal
Mol Microbiol 42:573-85 (2001)
DOI:10.1046/j.1365-2958.2001.02581.x
Reference
  Authors
Szurmant H, Bunn MW, Cannistraro VJ, Ordal GW.
  Title
Bacillus subtilis hydrolyzes CheY-P at the location of its action, the flagellar switch.
  Journal
J Biol Chem 278:48611-6 (2003)
DOI:10.1074/jbc.M306180200
Reference
  Authors
Szurmant H, Muff TJ, Ordal GW.
  Title
Bacillus subtilis CheC and FliY are members of a novel class of CheY-P-hydrolyzing proteins in the chemotactic signal transduction cascade.
  Journal
J Biol Chem 279:21787-92 (2004)
DOI:10.1074/jbc.M311497200
Reference
  Authors
Yoshihara S, Geng X, Okamoto S, Yura K, Murata T, Go M, Ohmori M, Ikeuchi M.
  Title
Mutational analysis of genes involved in pilus structure, motility and transformation competency in the unicellular motile cyanobacterium Synechocystis sp. PCC 6803.
  Journal
Plant Cell Physiol 42:63-73 (2001)
DOI:10.1093/pcp/pce007
Reference
PMID:8104179
  Authors
Darzins A.
  Title
The pilG gene product, required for Pseudomonas aeruginosa pilus production and twitching motility, is homologous to the enteric, single-domain response regulator CheY.
  Journal
J Bacteriol 175:5934-44 (1993)
DOI:10.1128/JB.175.18.5934-5944.1993
Reference
  Authors
Szurmant H, Ordal GW
  Title
Diversity in chemotaxis mechanisms among the bacteria and archaea.
  Journal
Microbiol Mol Biol Rev 68:301-19 (2004)
DOI:10.1128/MMBR.68.2.301-319.2004
Reference
  Authors
Rao CV, Glekas GD, Ordal GW
  Title
The three adaptation systems of Bacillus subtilis chemotaxis.
  Journal
Trends Microbiol 16:480-7 (2008)
DOI:10.1016/j.tim.2008.07.003
Reference
  Authors
Muff TJ, Ordal GW
  Title
The diverse CheC-type phosphatases: chemotaxis and beyond.
  Journal
Mol Microbiol 70:1054-61 (2008)
DOI:10.1111/j.1365-2958.2008.06482.x
Reference
  Authors
Miller LD, Russell MH, Alexandre G
  Title
Diversity in bacterial chemotactic responses and niche adaptation.
  Journal
Adv Appl Microbiol 66:53-75 (2009)
DOI:10.1016/S0065-2164(08)00803-4
Related
pathway
bvi02040  Flagellar assembly
KO pathway
ko02030   
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