KEGG   PATHWAY: eha01230
Entry
eha01230                    Pathway                                
Name
Biosynthesis of amino acids - Ethanoligenens harbinense
Description
This map presents a modular architecture of the biosynthesis pathways of twenty amino acids, which may be viewed as consisting of the core part and its extensions. The core part is the KEGG module for conversion of three-carbon compounds from glyceraldehyde-3P to pyruvate [MD:M00002], together with the pathways around serine and glycine. This KEGG module is the most conserved one in the KEGG MODULE database and is found in almost all the completely sequenced genomes. The extensions are the pathways containing the reaction modules RM001, RM033, RM032, and RM002 for biosynthesis of branched-chain amino acids (left) and basic amino acids (bottom), and the pathways for biosynthesis of histidine and aromatic amino acids (top right). It is interesting to note that the so-called essential amino acids that cannot be synthesized in human and other organisms generally appear in these extensions. Furthermore, the bottom extension of basic amino acids appears to be most divergent containing multiple pathways for lysine biosynthesis and multiple gene sets for arginine biosynthesis.
Class
Pathway map
eha01230  Biosynthesis of amino acids
eha01230

Module
eha_M00002  Glycolysis, core module involving three-carbon compounds [PATH:eha01230]
eha_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:eha01230]
eha_M00007  Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:eha01230]
eha_M00015  Proline biosynthesis, glutamate => proline [PATH:eha01230]
eha_M00018  Threonine biosynthesis, aspartate => homoserine => threonine [PATH:eha01230]
eha_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:eha01230]
eha_M00021  Cysteine biosynthesis, serine => cysteine [PATH:eha01230]
eha_M00023  Tryptophan biosynthesis, chorismate => tryptophan [PATH:eha01230]
eha_M00026  Histidine biosynthesis, PRPP => histidine [PATH:eha01230]
eha_M00028  Ornithine biosynthesis, glutamate => ornithine [PATH:eha01230]
eha_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:eha01230]
eha_M00527  Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine [PATH:eha01230]
eha_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:eha01230]
eha_M00844  Arginine biosynthesis, ornithine => arginine [PATH:eha01230]
Organism
Ethanoligenens harbinense [GN:eha]
KO pathway
ko01230   
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