KEGG   PATHWAY: ger02030
Entry
ger02030                    Pathway                                
Name
Bacterial chemotaxis - Geomonas oryzisoli
Description
Chemotaxis is the process by which cells sense chemical gradients in their environment and then move towards more favorable conditions. In chemotaxis, events at the receptors control autophosphorylation of the CheA histidine kinase, and the phosphohistidine is the substrate for the response regulator CheY, which catalyzes the transfer of the phosphoryl group to a conserved aspartate. The resulting CheY-P can interact with the switch mechanism in the motor. This interaction causes a change in behavior, such as in direction or speed of rotation of flagella.
Class
Cellular Processes; Cell motility
Pathway map
ger02030  Bacterial chemotaxis
ger02030

Other DBs
GO: 0006935
Organism
Geomonas oryzisoli [GN:ger]
Gene
KP004_01540  HAMP domain-containing protein [KO:K03406]
KP004_02405  methyl-accepting chemotaxis protein [KO:K03406]
KP004_02680  HAMP domain-containing protein [KO:K03406]
KP004_03315  methyl-accepting chemotaxis protein [KO:K03406]
KP004_04030  MCP four helix bundle domain-containing protein [KO:K03406]
KP004_04600  methyl-accepting chemotaxis protein [KO:K03406]
KP004_04815  MCP four helix bundle domain-containing protein [KO:K03406]
KP004_04825  MCP four helix bundle domain-containing protein [KO:K03406]
KP004_05740  methyl-accepting chemotaxis protein [KO:K03406]
KP004_05930  MCP four helix bundle domain-containing protein [KO:K03406]
KP004_06545  cache domain-containing protein [KO:K03406]
KP004_06595  MCP four helix bundle domain-containing protein [KO:K03406]
KP004_08765  methyl-accepting chemotaxis protein [KO:K03406]
KP004_08940  MCP four helix bundle domain-containing protein [KO:K03406]
KP004_09345  MCP four helix bundle domain-containing protein [KO:K03406]
KP004_10210  methyl-accepting chemotaxis protein [KO:K03406]
KP004_11255  methyl-accepting chemotaxis protein [KO:K03406]
KP004_11345  chemotaxis protein [KO:K03406]
KP004_13110  methyl-accepting chemotaxis protein [KO:K03406]
KP004_14085  methyl-accepting chemotaxis protein [KO:K03406]
KP004_14400  cache domain-containing protein [KO:K03406]
KP004_15005  cache domain-containing protein [KO:K03406]
KP004_16220  methyl-accepting chemotaxis protein [KO:K03406]
KP004_17350  methyl-accepting chemotaxis protein [KO:K03406]
KP004_17365  methyl-accepting chemotaxis protein [KO:K03406]
KP004_18565  CHASE3 domain-containing protein [KO:K03406]
KP004_18570  methyl-accepting chemotaxis protein [KO:K03406]
KP004_19795  bacteriohemerythrin [KO:K03406]
KP004_20925  methyl-accepting chemotaxis protein [KO:K03406]
KP004_20950  methyl-accepting chemotaxis protein [KO:K03406]
KP004_02390  chemotaxis protein CheA [KO:K03407] [EC:2.7.13.3]
KP004_03005  chemotaxis protein CheA [KO:K03407] [EC:2.7.13.3]
KP004_05940  chemotaxis protein CheA [KO:K03407] [EC:2.7.13.3]
KP004_09145  response regulator [KO:K03407] [EC:2.7.13.3]
KP004_10870  hybrid sensor histidine kinase/response regulator [KO:K03407] [EC:2.7.13.3]
KP004_12180  chemotaxis protein CheA [KO:K03407] [EC:2.7.13.3]
KP004_14125  chemotaxis protein CheA [KO:K03407] [EC:2.7.13.3]
KP004_14995  chemotaxis protein CheW [KO:K03407] [EC:2.7.13.3]
KP004_19045  chemotaxis protein CheA [KO:K03407] [EC:2.7.13.3]
KP004_02400  chemotaxis protein CheW [KO:K03408]
KP004_03015  chemotaxis protein CheW [KO:K03408]
KP004_03025  chemotaxis protein CheW [KO:K03408]
KP004_04820  chemotaxis protein CheW [KO:K03408]
KP004_09155  chemotaxis protein CheW [KO:K03408]
KP004_09165  chemotaxis protein CheW [KO:K03408]
KP004_10125  chemotaxis protein CheW [KO:K03408]
KP004_10860  chemotaxis protein CheW [KO:K03408]
KP004_14120  chemotaxis protein CheW [KO:K03408]
KP004_15000  chemotaxis protein CheW [KO:K03408]
KP004_19040  chemotaxis protein CheW [KO:K03408]
KP004_00930  response regulator [KO:K03413]
KP004_02395  response regulator [KO:K03413]
KP004_03000  response regulator [KO:K03413]
KP004_03055  response regulator [KO:K03413]
KP004_05965  response regulator [KO:K03413]
KP004_10175  response regulator [KO:K03413]
KP004_10880  response regulator [KO:K03413]
KP004_12185  response regulator [KO:K03413]
KP004_14130  response regulator [KO:K03413]
KP004_14135  response regulator [KO:K03413]
KP004_18385  response regulator [KO:K03413]
KP004_19890  response regulator [KO:K03413]
KP004_10215  response regulator [KO:K03413]
KP004_02385  chemotaxis protein CheC [KO:K03410]
KP004_04125  chemotaxis protein CheX [KO:K03409]
KP004_18380  chemotaxis protein CheX [KO:K03409]
KP004_20975  chemotaxis protein CheX [KO:K03409]
KP004_03045  chemotaxis response regulator protein-glutamate methylesterase [KO:K03412] [EC:3.1.1.61 3.5.1.44]
KP004_09140  cheB; chemotaxis-specific protein-glutamate methyltransferase CheB [KO:K03412] [EC:3.1.1.61 3.5.1.44]
KP004_10875  cheB; chemotaxis-specific protein-glutamate methyltransferase CheB [KO:K03412] [EC:3.1.1.61 3.5.1.44]
KP004_12165  chemotaxis response regulator protein-glutamate methylesterase [KO:K03412] [EC:3.1.1.61 3.5.1.44]
KP004_14095  chemotaxis response regulator protein-glutamate methylesterase [KO:K03412] [EC:3.1.1.61 3.5.1.44]
KP004_15020  chemotaxis response regulator protein-glutamate methylesterase [KO:K03412] [EC:3.1.1.61 3.5.1.44]
KP004_19060  chemotaxis response regulator protein-glutamate methylesterase [KO:K03412] [EC:3.1.1.61 3.5.1.44]
KP004_20140  chemotaxis protein CheB [KO:K03412] [EC:3.1.1.61 3.5.1.44]
KP004_18020  PAS domain-containing protein [KO:K13924] [EC:2.1.1.80 3.1.1.61]
KP004_02855  chemotaxis protein [KO:K03415]
KP004_12170  chemotaxis protein CheD [KO:K03411] [EC:3.5.1.44]
KP004_13145  chemotaxis protein CheD [KO:K03411] [EC:3.5.1.44]
KP004_15015  histidine kinase [KO:K03411] [EC:3.5.1.44]
KP004_02410  protein-glutamate O-methyltransferase CheR [KO:K00575] [EC:2.1.1.80]
KP004_03040  protein-glutamate O-methyltransferase CheR [KO:K00575] [EC:2.1.1.80]
KP004_05920  chemotaxis protein CheR [KO:K00575] [EC:2.1.1.80]
KP004_06420  hypothetical protein [KO:K00575] [EC:2.1.1.80]
KP004_09160  chemotaxis protein CheR [KO:K00575] [EC:2.1.1.80]
KP004_12175  protein-glutamate O-methyltransferase [KO:K00575] [EC:2.1.1.80]
KP004_14100  protein-glutamate O-methyltransferase CheR [KO:K00575] [EC:2.1.1.80]
KP004_14110  protein-glutamate O-methyltransferase CheR [KO:K00575] [EC:2.1.1.80]
KP004_15010  methyltransferase domain-containing protein [KO:K00575] [EC:2.1.1.80]
KP004_19050  protein-glutamate O-methyltransferase CheR [KO:K00575] [EC:2.1.1.80]
KP004_18345  fliG; flagellar motor switch protein FliG [KO:K02410]
KP004_18295  fliM; flagellar motor switch protein FliM [KO:K02416]
KP004_18290  fliN; flagellar motor switch protein FliN [KO:K02417]
KP004_00080  flagellar motor protein [KO:K02556]
KP004_00085  OmpA family protein [KO:K02557]
KP004_03285  OmpA family protein [KO:K02557]
Compound
C00049  L-Aspartate
C00107  Dipeptide
C00121  D-Ribose
C00124  D-Galactose
C00208  Maltose
C00716  Serine
Reference
PMID:12011078
  Authors
Kristich CJ, Ordal GW.
  Title
Bacillus subtilis CheD is a chemoreceptor modification enzyme required for chemotaxis.
  Journal
J Biol Chem 277:25356-62 (2002)
DOI:10.1074/jbc.M201334200
Reference
PMID:11722727
  Authors
Kirby JR, Kristich CJ, Saulmon MM, Zimmer MA, Garrity LF, Zhulin IB, Ordal GW.
  Title
CheC is related to the family of flagellar switch proteins and acts independently from CheD to control chemotaxis in Bacillus subtilis.
  Journal
Mol Microbiol 42:573-85 (2001)
DOI:10.1046/j.1365-2958.2001.02581.x
Reference
PMID:12920116
  Authors
Szurmant H, Bunn MW, Cannistraro VJ, Ordal GW.
  Title
Bacillus subtilis hydrolyzes CheY-P at the location of its action, the flagellar switch.
  Journal
J Biol Chem 278:48611-6 (2003)
DOI:10.1074/jbc.M306180200
Reference
PMID:14749334
  Authors
Szurmant H, Muff TJ, Ordal GW.
  Title
Bacillus subtilis CheC and FliY are members of a novel class of CheY-P-hydrolyzing proteins in the chemotactic signal transduction cascade.
  Journal
J Biol Chem 279:21787-92 (2004)
DOI:10.1074/jbc.M311497200
Reference
PMID:11158445
  Authors
Yoshihara S, Geng X, Okamoto S, Yura K, Murata T, Go M, Ohmori M, Ikeuchi M.
  Title
Mutational analysis of genes involved in pilus structure, motility and transformation competency in the unicellular motile cyanobacterium Synechocystis sp. PCC 6803.
  Journal
Plant Cell Physiol 42:63-73 (2001)
DOI:10.1093/pcp/pce007
Reference
PMID:8104179
  Authors
Darzins A.
  Title
The pilG gene product, required for Pseudomonas aeruginosa pilus production and twitching motility, is homologous to the enteric, single-domain response regulator CheY.
  Journal
J Bacteriol 175:5934-44 (1993)
DOI:10.1128/JB.175.18.5934-5944.1993
Reference
PMID:15187186
  Authors
Szurmant H, Ordal GW
  Title
Diversity in chemotaxis mechanisms among the bacteria and archaea.
  Journal
Microbiol Mol Biol Rev 68:301-19 (2004)
DOI:10.1128/MMBR.68.2.301-319.2004
Reference
PMID:18774298
  Authors
Rao CV, Glekas GD, Ordal GW
  Title
The three adaptation systems of Bacillus subtilis chemotaxis.
  Journal
Trends Microbiol 16:480-7 (2008)
DOI:10.1016/j.tim.2008.07.003
Reference
PMID:18990184
  Authors
Muff TJ, Ordal GW
  Title
The diverse CheC-type phosphatases: chemotaxis and beyond.
  Journal
Mol Microbiol 70:1054-61 (2008)
DOI:10.1111/j.1365-2958.2008.06482.x
Reference
PMID:19203648
  Authors
Miller LD, Russell MH, Alexandre G
  Title
Diversity in bacterial chemotactic responses and niche adaptation.
  Journal
Adv Appl Microbiol 66:53-75 (2009)
DOI:10.1016/S0065-2164(08)00803-4
Related
pathway
ger02040  Flagellar assembly
KO pathway
ko02030   
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