Entry
Name
Polyketide sugar unit biosynthesis
Class
Metabolism; Metabolism of terpenoids and polyketides
BRITE hierarchy
Pathway map
map00523 Polyketide sugar unit biosynthesis
Ortholog table
Module
Reference
Authors
Rawlings BJ.
Title
Type I polyketide biosynthesis in bacteria (Part A--erythromycin biosynthesis).
Journal
Reference
Authors
Rawlings BJ.
Title
Type I polyketide biosynthesis in bacteria (part B).
Journal
Reference
Authors
Wohlert S, Lomovskaya N, Kulowski K, Fonstein L, Occi JL, Gewain KM, MacNeil DJ, Hutchinson CR
Title
Insights about the biosynthesis of the avermectin deoxysugar L-oleandrose through heterologous expression of Streptomyces avermitilis deoxysugar genes in Streptomyces lividans.
Journal
Reference
Authors
Bate N, Butler AR, Smith IP, Cundliffe E
Title
The mycarose-biosynthetic genes of Streptomyces fradiae, producer of tylosin.
Journal
Reference
Authors
Amann S, Drager G, Rupprath C, Kirschning A, Elling L
Title
(Chemo)enzymatic synthesis of dTDP-activated 2,6-dideoxysugars as building blocks of polyketide antibiotics.
Journal
Reference
Authors
Thibodeaux CJ, Melancon CE, Liu HW
Title
Unusual sugar biosynthesis and natural product glycodiversification.
Journal
Reference
Authors
Volchegursky Y, Hu Z, Katz L, McDaniel R
Title
Biosynthesis of the anti-parasitic agent megalomicin: transformation of erythromycin to megalomicin in Saccharopolyspora erythraea.
Journal
Reference
Authors
Mironov VA, Sergienko OV, Nastasiak IN, Danilenko VN.
Title
Biogenesis and regulation of biosynthesis of erythromycins in Saccharopolyspora.
Journal
Reference
Authors
Tello M, Jakimowicz P, Errey JC, Freel Meyers CL, Walsh CT, Buttner MJ, Lawson DM, Field RA
Title
Characterisation of Streptomyces spheroides NovW and revision of its functional assignment to a dTDP-6-deoxy-D-xylo-4-hexulose 3-epimerase.
Journal
Reference
Authors
Takahashi H, Liu YN, Chen H, Liu HW
Title
Biosynthesis of TDP-l-mycarose: the specificity of a single enzyme governs the outcome of the pathway.
Journal
Reference
Authors
Aguirrezabalaga I, Olano C, Allende N, Rodriguez L, Brana AF, Mendez C, Salas JA
Title
Identification and expression of genes involved in biosynthesis of L-oleandrose and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticus.
Journal
Reference
Authors
Rodriguez L, Rodriguez D, Olano C, Brana AF, Mendez C, Salas JA
Title
Functional analysis of OleY L-oleandrosyl 3-O-methyltransferase of the oleandomycin biosynthetic pathway in Streptomyces antibioticus.
Journal
Reference
Authors
Useglio M, Peiru S, Rodriguez E, Labadie GR, Carney JR, Gramajo H
Title
TDP-L-megosamine biosynthesis pathway elucidation and megalomicin a production in Escherichia coli.
Journal
Reference
Authors
Liu W, Christenson SD, Standage S, Shen B
Title
Biosynthesis of the enediyne antitumor antibiotic C-1027.
Journal
Reference
Authors
Van Lanen SG, Oh TJ, Liu W, Wendt-Pienkowski E, Shen B
Title
Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis.
Journal
Reference
Authors
Gao Q, Zhang C, Blanchard S, Thorson JS
Title
Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus.
Journal
Reference
Authors
Simkhada D, Oh TJ, Kim EM, Yoo JC, Sohng JK
Title
Cloning and characterization of CalS7 from Micromonospora echinospora sp. calichensis as a glucose-1-phosphate nucleotidyltransferase.
Journal
Reference
Authors
Singh S, Peltier-Pain P, Tonelli M, Thorson JS
Title
A general NMR-based strategy for the in situ characterization of sugar-nucleotide-dependent biosynthetic pathways.
Journal
Reference
Authors
Singh S, Chang A, Helmich KE, Bingman CA, Wrobel RL, Beebe ET, Makino S, Aceti DJ, Dyer K, Hura GL, Sunkara M, Morris AJ, Phillips GN Jr, Thorson JS
Title
Structural and functional characterization of CalS11, a TDP-rhamnose 3'-O-methyltransferase involved in calicheamicin biosynthesis.
Journal
Reference
Authors
Liang ZX
Title
Complexity and simplicity in the biosynthesis of enediyne natural products.
Journal
Reference
Authors
Singh S, Michalska K, Bigelow L, Endres M, Kharel MK, Babnigg G, Yennamalli RM, Bingman CA, Joachimiak A, Thorson JS, Phillips GN Jr
Title
Structural Characterization of CalS8, a TDP-alpha-D-Glucose Dehydrogenase Involved in Calicheamicin Aminodideoxypentose Biosynthesis.
Journal
Reference
Authors
Peltier-Pain P, Singh S, Thorson JS
Title
Characterization of Early Enzymes Involved in TDP-Aminodideoxypentose Biosynthesis en Route to Indolocarbazole AT2433.
Journal
Reference
Authors
Singh S, Kim Y, Wang F, Bigelow L, Endres M, Kharel MK, Babnigg G, Bingman CA, Joachimiak A, Thorson JS, Phillips GN Jr
Title
Structural characterization of AtmS13, a putative sugar aminotransferase involved in indolocarbazole AT2433 aminopentose biosynthesis.
Journal
Related pathway
map00520 Amino sugar and nucleotide sugar metabolism
map00522 Biosynthesis of 12-, 14- and 16-membered macrolides
map01059 Biosynthesis of enediyne antibiotics
KO pathway
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