KEGG   PATHWAY: pee04136
Entry
pee04136                    Pathway                                
Name
Autophagy - other - Phycodurus eques (leafy seadragon)
Description
Autophagy is a degradative pathway for the removal of cytoplasmic materials in eukaryotic cells, and is characterized by the formation of a double-membrane structure called the autophagosome, either in a housekeeping capacity or during stress and senescence. The process of autophagy could be divided into several stages: induction, vesicle nucleation, elongation and closure, and fusion and digestion. Most essential autophagic machineries are conserved throughout eukaryotes (see map04140 for animals and map04138 for fungi). This map is for other eukaryotes including plants and protists, where autophagy related genes (ATGs) play similar roles in the life cycle. However, autophagy has been relatively less studied in lower eukaryotes.
Class
Cellular Processes; Transport and catabolism
Pathway map
pee04136  Autophagy - other
pee04136

Other DBs
GO: 0006914
Organism
Phycodurus eques (leafy seadragon) [GN:pee]
Gene
133404352  rptor; regulatory-associated protein of mTOR isoform X1 [KO:K07204]
133399868  mtor; serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
133418182  mlst8; target of rapamycin complex subunit lst8 [KO:K08266]
133411086  atg13; autophagy-related protein 13 isoform X1 [KO:K08331]
133415892  atg101; autophagy-related protein 101 [KO:K19730]
133407768  igbp1; immunoglobulin-binding protein 1 [KO:K17606]
133400216  serine/threonine-protein phosphatase 2A catalytic subunit beta isoform [KO:K04382] [EC:3.1.3.16]
133407703  serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform-like isoform X1 [KO:K04382] [EC:3.1.3.16]
133415661  ppp2cab; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform [KO:K04382] [EC:3.1.3.16]
133412753  atg9a; autophagy-related protein 9A isoform X1 [KO:K17907]
133411175  atg9b; autophagy-related protein 9B [KO:K17907]
133412627  atg2b; autophagy-related protein 2 homolog B isoform X1 [KO:K17906]
133407419  atg2a; autophagy-related protein 2 homolog A isoform X1 [KO:K17906]
133417628  WD repeat domain phosphoinositide-interacting protein 1-like [KO:K17908]
133414884  wipi1; WD repeat domain phosphoinositide-interacting protein 1 isoform X1 [KO:K17908]
133415217  wipi2; WD repeat domain phosphoinositide-interacting protein 2 isoform X1 [KO:K17908]
133417686  becn1; beclin-1 isoform X1 [KO:K08334]
133398056  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
133401536  pik3r4; phosphoinositide 3-kinase regulatory subunit 4 isoform X1 [KO:K08333] [EC:2.7.11.1]
133402123  atg5; autophagy protein 5 [KO:K08339]
133404709  atg16l1; autophagy-related protein 16-1 isoform X1 [KO:K17890]
133408413  atg7; ubiquitin-like modifier-activating enzyme ATG7 isoform X1 [KO:K08337]
133412064  atg10; ubiquitin-like-conjugating enzyme ATG10 isoform X1 [KO:K17888]
133405891  atg3; ubiquitin-like-conjugating enzyme ATG3 isoform X1 [KO:K08343]
133401445  zgc:92606; gamma-aminobutyric acid receptor-associated protein-like 1 [KO:K08341]
133395687  gabarapl2; gamma-aminobutyric acid receptor-associated protein-like 2 [KO:K08341]
133397728  gamma-aminobutyric acid receptor-associated protein [KO:K08341]
133406403  atg4c; cysteine protease ATG4C isoform X1 [KO:K08342] [EC:3.4.22.-]
133406437  atg4b; cysteine protease ATG4B [KO:K08342] [EC:3.4.22.-]
133414695  cysteine protease atg4da-like [KO:K08342] [EC:3.4.22.-]
133404503  atg4da; cysteine protease atg4da [KO:K08342] [EC:3.4.22.-]
Compound
C00350  Phosphatidylethanolamine
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
Reference
  Authors
Duszenko M, Ginger ML, Brennand A, Gualdron-Lopez M, Colombo MI, Coombs GH, Coppens I, Jayabalasingham B, Langsley G, de Castro SL, Menna-Barreto R, Mottram JC, Navarro M, Rigden DJ, Romano PS, Stoka V, Turk B, Michels PA
  Title
Autophagy in protists.
  Journal
Autophagy 7:127-58 (2011)
DOI:10.4161/auto.7.2.13310
Reference
  Authors
Avin-Wittenberg T, Honig A, Galili G
  Title
Variations on a theme: plant autophagy in comparison to yeast and mammals.
  Journal
Protoplasma 249:285-99 (2012)
DOI:10.1007/s00709-011-0296-z
Reference
  Authors
Liu Y, Bassham DC
  Title
Autophagy: pathways for self-eating in plant cells.
  Journal
Annu Rev Plant Biol 63:215-37 (2012)
DOI:10.1146/annurev-arplant-042811-105441
Reference
  Authors
Yoshimoto K
  Title
Beginning to understand autophagy, an intracellular self-degradation system in plants.
  Journal
Plant Cell Physiol 53:1355-65 (2012)
DOI:10.1093/pcp/pcs099
Reference
  Authors
Li F, Chung T, Vierstra RD
  Title
AUTOPHAGY-RELATED11 plays a critical role in general autophagy- and senescence-induced mitophagy in Arabidopsis.
  Journal
Plant Cell 26:788-807 (2014)
DOI:10.1105/tpc.113.120014
Reference
  Authors
Michaeli S, Galili G, Genschik P, Fernie AR, Avin-Wittenberg T
  Title
Autophagy in Plants--What's New on the Menu?
  Journal
Trends Plant Sci 21:134-44 (2016)
DOI:10.1016/j.tplants.2015.10.008
Reference
  Authors
Yang X, Bassham DC
  Title
New Insight into the Mechanism and Function of Autophagy in Plant Cells.
  Journal
Int Rev Cell Mol Biol 320:1-40 (2015)
DOI:10.1016/bs.ircmb.2015.07.005
KO pathway
ko04136   
LinkDB

DBGET integrated database retrieval system