KEGG   PATHWAY: pxu04136
Entry
pxu04136                    Pathway                                
Name
Autophagy - other - Papilio xuthus (Asian swallowtail)
Description
Autophagy is a degradative pathway for the removal of cytoplasmic materials in eukaryotic cells, and is characterized by the formation of a double-membrane structure called the autophagosome, either in a housekeeping capacity or during stress and senescence. The process of autophagy could be divided into several stages: induction, vesicle nucleation, elongation and closure, and fusion and digestion. Most essential autophagic machineries are conserved throughout eukaryotes (see map04140 for animals and map04138 for fungi). This map is for other eukaryotes including plants and protists, where autophagy related genes (ATGs) play similar roles in the life cycle. However, autophagy has been relatively less studied in lower eukaryotes.
Class
Cellular Processes; Transport and catabolism
Pathway map
pxu04136  Autophagy - other
pxu04136

Other DBs
GO: 0006914
Organism
Papilio xuthus (Asian swallowtail) [GN:pxu]
Gene
106119010  protein raptor homolog [KO:K07204]
106126681  serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
106126722  serine/threonine-protein kinase mTOR-like [KO:K07203] [EC:2.7.11.1]
106115610  target of rapamycin complex subunit lst8 [KO:K08266]
106115857  serine/threonine-protein kinase unc-51 isoform X1 [KO:K08269] [EC:2.7.11.1]
106118686  autophagy-related protein 13 homolog [KO:K08331]
106126354  autophagy-related protein 13 homolog [KO:K08331]
106115756  autophagy-related protein 101 [KO:K19730]
106124006  immunoglobulin-binding protein 1 [KO:K17606]
106126792  serine/threonine-protein phosphatase 2A catalytic subunit beta isoform isoform X1 [KO:K04382] [EC:3.1.3.16]
106126412  autophagy-related protein 9A [KO:K17907]
106120205  autophagy-related protein 2 homolog A isoform X1 [KO:K17906]
106120998  WD repeat domain phosphoinositide-interacting protein 2 [KO:K17908]
106125835  beclin-1-like protein [KO:K08334]
106122537  phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
106128489  phosphoinositide 3-kinase regulatory subunit 4 isoform X1 [KO:K08333] [EC:2.7.11.1]
106121084  ubiquitin-like protein ATG12 [KO:K08336]
106117040  autophagy protein 5 [KO:K08339]
106122464  autophagy-related protein 16-1 isoform X1 [KO:K17890]
106119404  ubiquitin-like modifier-activating enzyme ATG7 [KO:K08337]
106124331  ubiquitin-like-conjugating enzyme ATG10 [KO:K17888]
106125908  ubiquitin-like-conjugating enzyme ATG3 [KO:K08343]
106120239  cysteine protease ATG4D [KO:K08342] [EC:3.4.22.-]
106127496  cysteine protease ATG4B [KO:K08342] [EC:3.4.22.-]
Compound
C00350  Phosphatidylethanolamine
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
Reference
  Authors
Duszenko M, Ginger ML, Brennand A, Gualdron-Lopez M, Colombo MI, Coombs GH, Coppens I, Jayabalasingham B, Langsley G, de Castro SL, Menna-Barreto R, Mottram JC, Navarro M, Rigden DJ, Romano PS, Stoka V, Turk B, Michels PA
  Title
Autophagy in protists.
  Journal
Autophagy 7:127-58 (2011)
DOI:10.4161/auto.7.2.13310
Reference
  Authors
Avin-Wittenberg T, Honig A, Galili G
  Title
Variations on a theme: plant autophagy in comparison to yeast and mammals.
  Journal
Protoplasma 249:285-99 (2012)
DOI:10.1007/s00709-011-0296-z
Reference
  Authors
Liu Y, Bassham DC
  Title
Autophagy: pathways for self-eating in plant cells.
  Journal
Annu Rev Plant Biol 63:215-37 (2012)
DOI:10.1146/annurev-arplant-042811-105441
Reference
  Authors
Yoshimoto K
  Title
Beginning to understand autophagy, an intracellular self-degradation system in plants.
  Journal
Plant Cell Physiol 53:1355-65 (2012)
DOI:10.1093/pcp/pcs099
Reference
  Authors
Li F, Chung T, Vierstra RD
  Title
AUTOPHAGY-RELATED11 plays a critical role in general autophagy- and senescence-induced mitophagy in Arabidopsis.
  Journal
Plant Cell 26:788-807 (2014)
DOI:10.1105/tpc.113.120014
Reference
  Authors
Michaeli S, Galili G, Genschik P, Fernie AR, Avin-Wittenberg T
  Title
Autophagy in Plants--What's New on the Menu?
  Journal
Trends Plant Sci 21:134-44 (2016)
DOI:10.1016/j.tplants.2015.10.008
Reference
  Authors
Yang X, Bassham DC
  Title
New Insight into the Mechanism and Function of Autophagy in Plant Cells.
  Journal
Int Rev Cell Mol Biol 320:1-40 (2015)
DOI:10.1016/bs.ircmb.2015.07.005
KO pathway
ko04136   
LinkDB

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