KEGG   PATHWAY: wcb01210
Entry
wcb01210                    Pathway                                
Name
2-Oxocarboxylic acid metabolism - Weissella cibaria
Description
2-Oxocarboxylic acids, also called 2-oxo acids and alpha-keto acids, are the most elementary set of metabolites that includes pyruvate (2-oxopropanoate), 2-oxobutanoate, oxaloacetate (2-oxosuccinate) and 2-oxoglutarate. This diagram illustrates the architecture of chain extension and modification reaction modules for 2-oxocarboxylic acids. The chain extension module RM001 is a tricarboxylic pathway where acetyl-CoA derived carbon is used to extend the chain length by one. The chain modification modules RM002 (including RM032) and RM033, together with a reductive amination step (RC00006 or RC00036), generate basic and branched-chain amino acids, respectively. The modification module RM030 is used in the biosynthesis of glucosinolates, a class of plant secondary metabolites, for conversion to oxime followed by addition of thio-glucose moiety. Furthermore, the chain extension from 2-oxoadipate to 2-oxosuberate is followed by coenzyme B biosynthesis in methonogenic archaea.
Class
Pathway map
wcb01210  2-Oxocarboxylic acid metabolism
wcb01210

Module
wcb_M00028  Ornithine biosynthesis, glutamate => ornithine [PATH:wcb01210]
Organism
Weissella cibaria [GN:wcb]
Related
pathway
wcb00020  Citrate cycle (TCA cycle)
wcb00220  Arginine biosynthesis
wcb00250  Alanine, aspartate and glutamate metabolism
wcb00260  Glycine, serine and threonine metabolism
wcb00270  Cysteine and methionine metabolism
wcb00290  Valine, leucine and isoleucine biosynthesis
wcb00300  Lysine biosynthesis
wcb00310  Lysine degradation
wcb00620  Pyruvate metabolism
wcb00640  Propanoate metabolism
wcb00680  Methane metabolism
KO pathway
ko01210   
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