Polyangium aurulentum: E8A73_032370
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Entry
E8A73_032370 CDS
T08107
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
pauu
Polyangium aurulentum
Pathway
pauu00260
Glycine, serine and threonine metabolism
pauu00261
Monobactam biosynthesis
pauu00270
Cysteine and methionine metabolism
pauu00300
Lysine biosynthesis
pauu01100
Metabolic pathways
pauu01110
Biosynthesis of secondary metabolites
pauu01120
Microbial metabolism in diverse environments
pauu01230
Biosynthesis of amino acids
Module
pauu_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
pauu_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
pauu00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
E8A73_032370 (thrA)
00270 Cysteine and methionine metabolism
E8A73_032370 (thrA)
00300 Lysine biosynthesis
E8A73_032370 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
E8A73_032370 (thrA)
Enzymes [BR:
pauu01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
E8A73_032370 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
E8A73_032370 (thrA)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
DUF7523
Motif
Other DBs
NCBI-ProteinID:
UQA55998
LinkDB
All DBs
Position
complement(8162515..8165010)
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AA seq
831 aa
AA seq
DB search
MTAAAWVVHKFGGTSVANAERYRNVARILDAEPADRQGVVVSAMSGVTDALIGLTKLAQR
RDEAWQGKLEELGKRHLDAIAELGLSDAAGLLDVLRKDLDDVSVLLRATALGRACSEQML
EVIAGYGELWSAQILAAYLRAQDVDAVFCDAREVLIAAPGEIGPIIQWEGSQARMDAWLE
AHPSRRLVITGYIASAPDGSPTTLKRNGSDFSAAIFGRLLDASSVTIWTDVDGVLSADPR
RVPEAIVLPEMSYAEAVELAYFGAKVLHPRTMAPAVDKGIPIWIRNTFNASHPGTKIHAG
GRAEGASAEPTHAVKGFSTVDDVALVNVEGTGMIGVPGIARRVFGALREVGVSVSLISQA
SSEHSICFAVPGAQGELARSTVERAFAQDVAQGGVERVSLVPDCSILAAVGDEMVHTAGV
AAKFFGALGKAGVNVRAIAQGSSERNISAVVDRRDANRALRAVHASFYLSDLTLSVGLVG
PGLVGRTLLAQLAAQAEALRAQFRIDLQVRAIADSRRMILSNGPIALDRWQDELASDRAV
PTDLEKLAAHVHAEHLPHAVIIDCSASEVVADRYVRWMEGGIHVITPNKRASAGPLSRYQ
ALRKLGRALRTHYFYEATVGAGLPVISTLRDLVQTGDRILKIEGVLSGTLAYVFNAFDGE
RPFSAVVAEAKRRGYTEPDPRDDLSGMDVARKLTILGREAGLGLELSEVQVESLVPPGCA
GVANAEAFLGCLERHDAAMTAKLTEARAQGEALRYVGVVDADGRASVSLRRYPLSHPFAR
ITGSDNIIAFTTERYRAQPLVVQGPGAGPDVTAGGVFADLLRLTAYLGAPS
NT seq
2496 nt
NT seq
+upstream
nt +downstream
nt
atgaccgccgctgcctgggtcgtgcacaagttcggcgggaccagcgtcgcgaacgccgag
cgctaccgcaacgtcgcgcgcatcctcgacgccgagcccgccgatcgtcagggcgtcgtg
gtgagcgccatgtccggcgtgaccgacgcgctcatcggcctcacgaagctcgcccagcgc
cgcgacgaggcctggcaaggcaagctcgaagagctcggaaagcgtcacctcgacgccatc
gccgagctcgggctgtcggatgcggccgggctcctcgacgttctccgcaaggacctcgac
gacgtgagcgtgctcctgcgcgcgaccgccctcggccgcgcgtgcagcgagcagatgctc
gaggtcatcgcgggctacggcgagctgtggagcgcgcagatcctcgccgcctacctgcgc
gcgcaggacgtggacgccgtcttctgcgacgcgcgcgaggtgctgatcgcagcgcccggc
gagatcggtccgatcatccagtgggagggctcgcaggcccgcatggacgcctggctcgag
gcgcacccgtcgcgcaggctcgtcatcaccggctacatcgccagcgcgcccgacggctct
ccgaccacgctcaagcgcaacggcagcgacttctccgcggccatcttcggccggctcctc
gacgcctcctcggtcacgatctggaccgacgtcgacggcgtgctctccgccgatccgcgg
cgcgtgcccgaggccatcgtgctgcccgagatgtcctacgccgaggccgtcgagctcgcg
tacttcggcgcgaaggtgctgcacccgcgcaccatggcccccgccgtcgacaaggggatc
ccgatctggatccgcaacaccttcaacgcctcccacccgggcacgaagatccacgcagga
ggacgcgccgagggagcctccgccgagcccacgcacgcggtgaagggcttctccacggtg
gacgacgtcgcgctcgtgaacgtggagggcacgggcatgatcggcgtgcccgggatcgcc
cggcgcgtgttcggcgcgctccgcgaggtcggcgtctcggtctcgctcatctcgcaggcc
agctcggagcactcgatctgcttcgcggtgccgggagcccagggcgagctcgcgaggagc
accgtcgagcgtgcgttcgcgcaggacgtggcgcaaggcggcgtcgagcgcgtgagcctc
gtccccgattgcagcatcctcgcggccgtgggcgacgagatggtccacaccgccggcgtc
gccgcgaagttcttcggcgcgctcggcaaggccggcgtgaacgtgcgggcgatcgcgcag
ggctcttccgagcgcaacatctccgccgtcgtcgatcgccgcgacgccaaccgcgccctg
cgcgcggtgcacgcgagcttctacctctccgacctcacgctctccgtcggcctcgtgggc
ccggggctcgtgggccgcaccctgctcgcccagctcgccgcccaggccgaggcgctgcgc
gcgcagttccgcatcgatcttcaggtccgcgcgatcgccgactcgcgccgcatgatcctg
tcgaacggccccatcgcgctcgatcgctggcaggacgagctcgcctccgatcgcgccgtg
ccgaccgacctcgaaaagctcgcggcccacgtccacgccgagcacctgccccacgcggtg
atcatcgactgcagcgcgagcgaggtcgtcgccgatcgttacgtgcgctggatggagggg
ggcatccacgtgatcacccccaacaagcgcgcgagcgccggcccgctctcccgctaccag
gcgctccgcaagctcggtcgcgccctgcgcacgcactacttctacgaggccaccgtcggc
gcaggcctccccgtgatcagcaccctgcgcgacctcgtgcagaccggcgatcgcatcctg
aagatcgagggcgtcctctcgggcacgctcgcctatgtcttcaacgccttcgacggcgaa
aggcccttctccgcggtggtcgccgaggccaagcgccgcggctacaccgagcccgacccg
cgcgacgacctgtcgggcatggacgtcgcccgcaagctgacgatcctcggccgcgaggcg
gggctcgggctcgagctctccgaggtgcaggtcgagagcctcgtgcccccgggctgcgct
ggcgtcgccaacgccgaggcgttcctcggctgcctcgaacgccacgacgccgccatgacc
gcgaagctcaccgaggcccgcgcgcaaggcgaggcgctgcgctacgtgggcgtggtcgat
gccgacggccgcgcgagcgtgtcgctgcgccgctacccgctctcgcaccccttcgcgcgg
atcacgggcagcgacaacatcatcgccttcaccaccgagcgctatcgcgcgcagcccctc
gtcgtgcagggcccaggcgccggccccgacgtgaccgcgggcggcgtgttcgcggatctg
ctccgcctcacggcctacctcggcgccccttcgtag
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