Cutibacterium acnes 266: PAZ_c04780
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Entry
PAZ_c04780 CDS
T01971
Symbol
iolA
Name
(GenBank) methylmalonate semialdehyde dehydrogenase
KO
K00140
malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:
1.2.1.18
1.2.1.27
]
Organism
paw
Cutibacterium acnes 266
Pathway
paw00280
Valine, leucine and isoleucine degradation
paw00410
beta-Alanine metabolism
paw00562
Inositol phosphate metabolism
paw00640
Propanoate metabolism
paw01100
Metabolic pathways
paw01120
Microbial metabolism in diverse environments
paw01200
Carbon metabolism
Brite
KEGG Orthology (KO) [BR:
paw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
PAZ_c04780 (iolA)
00562 Inositol phosphate metabolism
PAZ_c04780 (iolA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
PAZ_c04780 (iolA)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
PAZ_c04780 (iolA)
Enzymes [BR:
paw01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
PAZ_c04780 (iolA)
1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
PAZ_c04780 (iolA)
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Motif
Pfam:
Aldedh
SpoVT_C
Motif
Other DBs
NCBI-ProteinID:
AEE71675
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Position
498991..500415
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AA seq
474 aa
AA seq
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MKTIRQWVGGEYYEGSPLGVIPVENPATGEVTAELLQASKEDLDHTVEVARDAQKEWANY
SLSKRVAIMFKMRQLVLDHQDEMARLIVEEHGKNYSDAIGEIQRGRETFDFATAINVALK
GEYSHDVSTGVDIHTTRQPVGVVAGICPFNFPAMVPMWMHPLAVATGNAFILKPASPTPS
ASLLTAELYKEAGLPDGVFNVLSGDRRSVQDILVHPGIDAISFVGSTPVAHIVQDTGVSH
GKRVQALGGANNHAIVMPDSDLDFAAQHISASAFGAAGERCMALPVVVAVGGCGPQVAEK
VKKHAEAIKVGEGMGEGVEMGPVISAKAKDRIVGLIDDAEKRGSKVVLDGRGLTVPGYEN
GHFLGPTVLDDVPLDAPVYTEEVFGPVLAIVHADTYEEALKIVNAQPFGNGSAIFTNDGG
VARRFTLDVEAGMVGVNVPIPTPVAFYSFGGWKESLLGDTHIHGSRRRYLLHPC
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgaagaccattagacaatgggtcggtggtgagtactacgagggatctccgctgggagtg
attcccgttgagaaccccgcaaccggtgaggtaactgcagagctgttgcaggcgtccaag
gaagatttggaccacaccgtagaggtggcccgtgatgcgcagaaagagtgggcaaactac
tcgctgtcaaaacgagtggcgatcatgttcaagatgcgccagctcgtgctagaccaccag
gacgagatggcgcggctcattgtcgaggagcacggcaagaactactccgacgcgattggc
gaaatccagcgtggtcgggagacctttgacttcgcgacagcgatcaacgttgcccttaaa
ggcgaatactctcatgacgtgtccaccggagtcgacatccacaccacccgtcagccggtc
ggtgtcgtcgcgggtatctgcccgttcaacttcccagccatggtcccgatgtggatgcac
ccgctggccgttgctactggaaatgccttcattcttaagccagcatcgcctacgccgtcc
gcttcgctcctcaccgcggagctctacaaagaggccgggcttcccgacggcgtctttaac
gtgctttcgggggaccgccgcagtgttcaggacatcctggttcacccgggtatcgacgct
atttcgtttgttggttcgacgccagtggctcacattgtccaagacaccggcgtaagccat
ggcaagcgcgtccaggccctcggcggtgcgaacaaccacgccattgtcatgcccgacagc
gatctggactttgctgcccagcacatctccgcatccgctttcggagctgctggtgagcgt
tgcatggcccttcctgtggtcgtcgccgtcgggggctgcggtccgcaagtagccgagaaa
gttaagaagcatgccgaggccatcaaggtcggagagggcatgggcgagggtgtcgagatg
ggacccgtcatctccgccaaggccaaagatcgtatcgtcggcctcatcgatgatgcggag
aagcgtggttcgaaggtcgtccttgacgggcgcggccttacagtcccgggctacgagaac
gggcactttctcggcccgacagtccttgacgacgtgcccctggatgccccggtctacacc
gaggaggtttttggtccggtactcgccatcgtgcatgccgacacctacgaggaggcgctg
aagatcgtcaacgctcagccatttggtaacggttctgccatatttaccaacgatggcggt
gtggcccgtcgcttcacccttgatgtggaggcgggcatggttggtgtcaacgtgccgatt
ccgaccccggtcgcgttctattcgttcggtggctggaaggagtcgctgctgggcgatacc
cacattcacgggtccagaaggcgttaccttctacacccgtgctaa
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