Paenarthrobacter sp. YJN-D: HMI60_01185
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Entry
HMI60_01185 CDS
T10599
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
payn Paenarthrobacter sp. YJN-D
Pathway
payn00300
Lysine biosynthesis
payn00550
Peptidoglycan biosynthesis
payn01100
Metabolic pathways
payn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
payn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HMI60_01185
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HMI60_01185
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HMI60_01185
Enzymes [BR:
payn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HMI60_01185
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QOT20251
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Position
246714..248204
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AA seq
496 aa
AA seq
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MIALTAAEIADITHGRLTGDPGIVPSSVVTDSREATPGSLYVAKPGEHADGHDFVDAAFE
RGAVLVLAEREVTDAHGSPYPAVVVDDAVLAMGALAAEAVRRIRADREQRGEQFTVIGIT
GSAGKTTTKDLLAGVLSTAGATVAPQGSYNGEVGVPLTVFAADTDTRFLVIEMGATGLGH
IKYLAEMVKPDIGVVLVVGTAHAGEFGGVENIAKTKGELVEALSENGTAVINLDDGRVAA
MRARTKAKVLGFTASPATTEEVEARNVVVNDQGFPDFDLILPDGGPSVPVRSRLIGGHHM
TNLLAAASAAFAAGIPAVDIASSLSSQSAASRWRMERTEREDGVTIINDAYNANPESMRA
ALRTLADLGQGRRTWAVLGAMLELGEDSIREHTAVGTQVVRLNISRLVVVGREARALYVS
AIQEGSWGDECSFTETVEEAYELLQNELRPGDLVLFKSSNGVGLRHLGDRIALPPRAEPT
GESAAEAAASEGNEQL
NT seq
1491 nt
NT seq
+upstream
nt +downstream
nt
atgattgcacttactgcggcggagatcgccgacatcacccatggccgtttgaccggagat
ccgggcatcgtgccctcctctgtggttactgactcacgggaggcgacgcccggctcgttg
tacgtggccaaacccggcgagcacgccgatggccacgacttcgtcgacgccgcgtttgag
cgtggcgccgttctggtcctcgccgaacgtgaggtgaccgatgcccacggcagcccatat
cccgccgtcgtggtcgatgacgctgtcctggccatgggcgccctggcggctgaagcggtc
cggcgcatccgggccgaccgcgaacagcgcggcgagcagttcacggtcattggaatcacc
ggctcagccggcaagaccaccaccaaggatctccttgccggcgtgttgtcgacggcaggc
gccactgtggcgccacagggttcgtacaacggcgaggtgggtgttccgctcacggttttt
gccgctgacaccgatacgcgcttccttgtcatcgagatgggtgccaccggcctgggccac
atcaagtacctcgcggagatggtcaagccggacatcggtgtagtcctggtagtcgggacc
gcccatgccggcgaattcggcggtgtggagaacatcgccaaaaccaagggtgaactggtc
gaagcccttagcgaaaacggcactgcggtcatcaacctcgacgacggccgcgtagctgcc
atgcgcgcccgcaccaaggccaaggtcctggggttcacggcctcgcccgctacgaccgaa
gaggtggaagcccgcaacgtcgtggtcaacgaccagggcttccccgacttcgacctcata
cttcccgacggcggtccttctgttccggtgcggagccgcctgatcggtggccaccacatg
accaacctgctcgcagctgcgtcagcggcttttgcggccgggatcccagccgtcgacatc
gcctcgtcactcagctcccagtcggcagccagccgttggcgcatggagcgaacagaacgt
gaagacggcgtgaccatcatcaacgatgcctacaacgcgaacccggaatccatgcgcgct
gctctgcgcactcttgcagaccttggacaaggcaggaggacctgggctgtccttggcgcc
atgctcgagctgggcgaagactccatccgcgaacacactgcggttggcactcaggtggtc
cggctgaacatctccaggctggtggtggtgggacgcgaagcccgcgccctctacgtctct
gccatccaggaaggctcctggggggatgaatgttccttcaccgagactgtggaggaagca
tacgaactcctgcagaacgaactcagaccaggcgacctcgtgttgttcaagtcctccaat
ggtgtggggctcaggcacttgggggatcggatagcattacctccacgggccgagcccacc
ggagaaagcgcggctgaagctgccgcaagcgaagggaacgagcagctgtga
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