Prionailurus bengalensis (leopard cat): 122467554
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Entry
122467554 CDS
T07574
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial isoform X1
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg00020
Citrate cycle (TCA cycle)
pbg00480
Glutathione metabolism
pbg01100
Metabolic pathways
pbg01200
Carbon metabolism
pbg01210
2-Oxocarboxylic acid metabolism
pbg01230
Biosynthesis of amino acids
pbg04146
Peroxisome
pbg05230
Central carbon metabolism in cancer
Module
pbg_M00009
Citrate cycle (TCA cycle, Krebs cycle)
pbg_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
122467554 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
122467554 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
122467554 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
122467554 (IDH2)
Enzymes [BR:
pbg01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
122467554 (IDH2)
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
122467554
NCBI-ProteinID:
XP_043409872
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Position
B3:5902115..5920406
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AA seq
451 aa
AA seq
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MAGYLRVVRSLCRASGSGPAWAPAAPTGPNLQEQPRRHYADKRIKVAKPVVEMDGDEMTR
IIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK
ATDFVVDRAGTFKIVFSPKDGSGAKEWEVFNFPAGGVGMGMYNTDESISGFAHSCFQYAI
QKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKHKIWYEHRLIDDMVAQVLKS
SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVQTVESGAMTKDLAGCIH
GLSNVKLNEHFLNTSDFLDTIKNNLDKALGQ
NT seq
1356 nt
NT seq
+upstream
nt +downstream
nt
atggctgggtacctgcgggtcgtacgctcgctctgcagggcctccggctccgggccggcc
tgggcgccggcagccccgacaggccccaacttgcaggagcagccgcggcgccactatgcc
gacaagaggatcaaggtggcgaagccggtggtggagatggacggcgatgagatgacccgg
atcatctggcagttcatcaaggagaagctcatcctgccgcacgtggatgtccagctcaag
tatttcgacctggggctcccaaaccgtgaccagaccaacgaccaggtcaccatagactcc
gcactggccacccagaagtacagtgtggctgtgaagtgcgccaccatcacccccgatgag
gcccgtgtggaagaattcaagctgaagaagatgtggaagagtcccaatggaaccatccga
aacatccttggggggaccgtcttccgggaacccatcatctgcaaaaacatcccacgcctc
gtccccggctggaccaagcccatcaccattggcaggcacgcccatggcgaccagtacaag
gccacggactttgtggtcgaccgggccggcacgttcaagatcgtcttctccccgaaggat
ggcagtggcgctaaggagtgggaagtgttcaatttccctgccggcggcgtggggatgggc
atgtacaacacggatgagtccatctcgggttttgcgcacagctgcttccagtacgccatc
cagaagaagtggccgctgtacatgagcaccaagaacaccatcctgaaggcctacgacggg
cgcttcaaggacatcttccaggaaatctttgacaagcactataagaccgacttcgacaag
cataagatctggtacgagcaccggctcattgatgacatggtggctcaggtcctcaagtct
tcaggcggcttcgtgtgggcctgcaagaactatgatggagacgtgcagtcggacatcctg
gcccagggctttggctccctcggcctgatgacgtctgtgctggtctgcccagatgggaag
accatcgaggctgaggccgctcatgggacggtcacccgccattatagggagcaccagaag
ggccggcctaccagcaccaaccccatcgccagcatctttgcctggacgcgtggcctggag
caccgggggaagctggatgggaaccaggacctcatcaggtttgcacagaccctggagaag
gtgtgtgtccagacggtggagagcggagccatgaccaaggacctggcgggctgcatccat
ggcctcagcaacgtgaagctgaacgagcacttcctgaacacctcggacttcctggacacc
atcaagaacaacctggacaaggccctgggccagtag
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