Prionailurus bengalensis (leopard cat): 122468290
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Entry
122468290 CDS
T07574
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg01521
EGFR tyrosine kinase inhibitor resistance
pbg01522
Endocrine resistance
pbg04010
MAPK signaling pathway
pbg04014
Ras signaling pathway
pbg04015
Rap1 signaling pathway
pbg04066
HIF-1 signaling pathway
pbg04068
FoxO signaling pathway
pbg04081
Hormone signaling
pbg04114
Oocyte meiosis
pbg04140
Autophagy - animal
pbg04144
Endocytosis
pbg04150
mTOR signaling pathway
pbg04151
PI3K-Akt signaling pathway
pbg04152
AMPK signaling pathway
pbg04211
Longevity regulating pathway
pbg04213
Longevity regulating pathway - multiple species
pbg04510
Focal adhesion
pbg04520
Adherens junction
pbg04550
Signaling pathways regulating pluripotency of stem cells
pbg04730
Long-term depression
pbg04913
Ovarian steroidogenesis
pbg04914
Progesterone-mediated oocyte maturation
pbg05200
Pathways in cancer
pbg05202
Transcriptional misregulation in cancer
pbg05205
Proteoglycans in cancer
pbg05214
Glioma
pbg05215
Prostate cancer
pbg05218
Melanoma
pbg05224
Breast cancer
pbg05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122468290 (IGF1R)
04014 Ras signaling pathway
122468290 (IGF1R)
04015 Rap1 signaling pathway
122468290 (IGF1R)
04066 HIF-1 signaling pathway
122468290 (IGF1R)
04068 FoxO signaling pathway
122468290 (IGF1R)
04151 PI3K-Akt signaling pathway
122468290 (IGF1R)
04152 AMPK signaling pathway
122468290 (IGF1R)
04150 mTOR signaling pathway
122468290 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
122468290 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
122468290 (IGF1R)
04140 Autophagy - animal
122468290 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
122468290 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
122468290 (IGF1R)
04520 Adherens junction
122468290 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
122468290 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
122468290 (IGF1R)
04914 Progesterone-mediated oocyte maturation
122468290 (IGF1R)
09156 Nervous system
04730 Long-term depression
122468290 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
122468290 (IGF1R)
04213 Longevity regulating pathway - multiple species
122468290 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122468290 (IGF1R)
05202 Transcriptional misregulation in cancer
122468290 (IGF1R)
05205 Proteoglycans in cancer
122468290 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
122468290 (IGF1R)
05214 Glioma
122468290 (IGF1R)
05218 Melanoma
122468290 (IGF1R)
05215 Prostate cancer
122468290 (IGF1R)
05224 Breast cancer
122468290 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
122468290 (IGF1R)
01522 Endocrine resistance
122468290 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pbg01001
]
122468290 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pbg04090
]
122468290 (IGF1R)
Enzymes [BR:
pbg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
122468290 (IGF1R)
Protein kinases [BR:
pbg01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
122468290 (IGF1R)
CD molecules [BR:
pbg04090
]
Proteins
122468290 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
122468290
NCBI-ProteinID:
XP_043410713
LinkDB
All DBs
Position
B3:complement(17312083..17621903)
Genome browser
AA seq
1367 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTDSNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPTCPPNTYRFEGWRCVDRDFCANIPSAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWGHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVTQVTNTTMSSRSRNITVADTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
ESRPENSIFLKWPEPENPNGLILMYEIKYGSQIEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVPAKITYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEIENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPEDMESVPLDPSASSSSLPLPDRH
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttttctcc
gccgcgctctcgctctggccgacgagtggagaaatctgcgggccgggcatcgatatccgt
aacgactatcagcagctgaagcgcctggagaactgcacggtgatcgagggctacctccac
atcctgctcatctccaaggcagaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacttgctgctgttccgcgtggccggcctcgagagcctcggggacctcttc
ccgaacctcacggtcatccgcggctggaaactcttctacaactacgccctggtcatcttt
gagatgaccaatctcaaggatattgggctttacaatctgaggaacattacccggggggcc
atcaggattgagaaaaacgctgacctctgttacctctccacggtggactggtccctaatc
ctggatgcggtgtctaataactacatcgtgggaaacaagcccccaaaggaatgcggggac
ctgtgtccggggacgatggaggagaagcccttgtgcgagaagacgaccatcaacaatgaa
tacaactaccgctgctggacgaccaaccgctgccagaaaatgtgcccgagcgcgtgcggg
aagcgggcgtgcacggacagcaacgagtgctgtcaccccgagtgcctgggcagctgcagc
gcgccggacaacgacacggcctgcgtggcctgcaggcattactactacgccggcgtctgc
gtgcccacctgcccgcccaacacctaccgctttgagggctggcgctgcgtggaccgcgac
ttctgcgccaacatccccagcgccgagagcagcgactccgaggggttcgtgatccatgac
ggcgagtgcatgcaggagtgcccctcggggttcatccggaacgggagtcagagcatgtac
tgcatcccttgtgaaggtccttgccccaaggtctgcgaggaggagaagaaaacaaagacc
attgattctgttacctctgctcaaatgctccaaggatgcaccatcttcaagggcaatctg
ctcattaatatccgccgaggcaataacattgcctcggagctggagaacttcatgggactc
atcgaggtggtgacaggctatgtgaagatccgccattcccacgccttggtctccttgtcc
ttcctcaaaaaccttcgccagatcttaggagaggagcagctggaggggaactactctttc
tatgtcctcgacaaccagaacctgcagcagctctgggactggggccaccgcaacctgacc
atcaaagctgggaagatgtactttgctttcaaccccaagttgtgcgtctccgaaatttac
cgcatggaggaggtgaccgggactaaggggcgccagagcaaaggggacatcaatacgagg
aacaacggagagcgagcctcctgtgaaagtgacgtcctgcacttcacctctacgaccacg
tggaagaaccgcatcatcataacctggcaccggtaccggccccctgactacagggacctc
atcagcttcaccgtctactacaaggaggcaccttttaaaaacgtcacggagtatgatggc
caggatgcctgtggctccaacagctggaacatggtagacgtggacctccctcccaacaag
gacgtcgagcctggcattttactgcacggactaaagccttggacgcagtatgctgtttac
gtcaaggcagtgaccctcaccatggtggagaatgaccacatccgcggggccaagagtgaa
atcttgtacattcgcaccaatgcttcagttccttccattcccctggatgttctttcggca
tcaaactcctcttctcagctcatcgtgaagtggaacccaccgtccctgcccaacggcaac
ctgagttactacatcgtgaggtggcagcggcagccccaggacagctacctttaccgccac
aactactgctccaaagacaaaatccccatcaggaagtatgccgatggcaccattgacgtc
gaggaggtgaccgaaaaccccaagaccgaagtgtgcggtggagagaaggggccttgctgt
gcctgccccaaaaccgaggccgagaagcaggcggagaaggaggaggctgagtaccgcaaa
gtcttcgagaacttcctgcacaactccatctttgtgcccagacctgaaaggaagcggaga
gatgtcacacaagtcaccaacaccaccatgtccagccgaagcaggaacatcacggtggca
gacacctataacatcacagaccccgaagagctcgagacagaataccctttctttgagagc
agagtggataacaaggagagaactgtgatctctaacctccggcctttcactttgtaccgc
attgacatccacagctgtaaccacgaggctgagaagctgggctgcagcgcctccaacttt
gtctttgcaagaaccatgcctgcagaaggagcagacgacattcctgggccagtgacctgg
gagtcaaggcctgaaaactccatatttttaaagtggccggaacctgagaatcccaatgga
ctgattctaatgtatgaaataaaatatggatcacaaatcgaggatcagcgggaatgtgta
tccagacaggagtaccggaagtatggaggcgccaagcttaaccggctcaacccggggaac
tatacggcccggatccaggccacctctctctctgggaatgggtcgtggacggatcccgtg
ttcttctacgtccccgccaaaataacatatgaaaatttcatccacctgatcatcgctctg
cctgttgccgtcctgctgatagtggggggactggttatcatgttgtacgtcttccacaga
aaaagaaataacagcaggctggggaatggagtgctgtatgcttcggtgaacccagagtac
ttcagtgccgcagatgtgtatgtacctgatgagtgggaggttgctcgggagaaaatcacc
atgagccgagagctggggcagggctcgtttgggatggtctacgaaggagttgccaaaggc
gtggttaaagatgagcctgaaaccagggtggccatcaaaacggtgaacgaggccgcgagc
atgcgtgaaaggattgaatttctcaacgaggcttcagtgatgaaggagttcaattgtcac
catgtggtgcggttgctgggcgtggtgtcccagggccagccgacgctggtcatcatggaa
ctgatgacgcggggtgatctcaaaagttatctcaggtctctgaggccagaaatagagaat
aatccagtcctagcacctccaagcctaagcaagatgatccagatggctggagagattgca
gacggcatggcatacctcaacgccaacaagtttgtccacagggaccttgctgcccggaac
tgcatggtggctgaagatttcacggtcaaaatcggagatttcggtatgacgagagatatc
tacgagacagactattaccggaaaggagggaaggggctgctgcctgtgcgctggatgtca
cccgagtccctcaaggatggggtcttcaccactcactctgacgtctggtccttcggggtc
gttctctgggagatcgccacgctggccgagcagccgtaccagggcttgtccaacgagcaa
gtgcttcgcttcgtcatggagggcggccttctggacaagccggacaactgccccgacatg
ctgtttgaactgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttcctg
gagatcatcagcagcatcaaggacgagatggaacccggcttccgggaggtctccttctac
tacagcgaggagaacaagccgcccgagccggaggagctggatctggagccggaggacatg
gagagcgtccccctggacccctccgcctcctcgtcctccctgccgctgcccgacagacac
tcaggacacaaggccgagaacggcccgggccccggcgtgctggttctccgagccagcttc
gacgagagacagccttacgcgcacatgaacgggggacgcaagaacgagagggccttgcct
ctgccccagtcttcgacctgctga
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integrated database retrieval system
