KEGG   Prionailurus bengalensis (leopard cat): 122472537
Entry
122472537         CDS       T07574                                 
Symbol
MGST1
Name
(RefSeq) microsomal glutathione S-transferase 1 isoform X1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
pbg  Prionailurus bengalensis (leopard cat)
Pathway
pbg00480  Glutathione metabolism
pbg00980  Metabolism of xenobiotics by cytochrome P450
pbg00982  Drug metabolism - cytochrome P450
pbg00983  Drug metabolism - other enzymes
pbg01100  Metabolic pathways
pbg01524  Platinum drug resistance
pbg05200  Pathways in cancer
pbg05204  Chemical carcinogenesis - DNA adducts
pbg05207  Chemical carcinogenesis - receptor activation
pbg05208  Chemical carcinogenesis - reactive oxygen species
pbg05225  Hepatocellular carcinoma
pbg05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pbg00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    122472537 (MGST1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    122472537 (MGST1)
   00982 Drug metabolism - cytochrome P450
    122472537 (MGST1)
   00983 Drug metabolism - other enzymes
    122472537 (MGST1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122472537 (MGST1)
   05204 Chemical carcinogenesis - DNA adducts
    122472537 (MGST1)
   05207 Chemical carcinogenesis - receptor activation
    122472537 (MGST1)
   05208 Chemical carcinogenesis - reactive oxygen species
    122472537 (MGST1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    122472537 (MGST1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    122472537 (MGST1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    122472537 (MGST1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:pbg02000]
    122472537 (MGST1)
Enzymes [BR:pbg01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     122472537 (MGST1)
Transporters [BR:pbg02000]
 Other transporters
  Pores ion channels [TC:1]
   122472537 (MGST1)
SSDB
Motif
Pfam: MAPEG
Other DBs
NCBI-GeneID: 122472537
NCBI-ProteinID: XP_043418130
LinkDB
Position
B4:49799774..49819809
AA seq 155 aa
MVDLTELMENEVFMAFASYTTIILSKMMFMSTATAFFRLTRKVFANPEDCAGFGKGENAK
KYLRTDDKVERVRRAHLNDLENIVPFLGIGLLYSLSGPDLSTAILHFRLFVGARIYHTVA
YLTPLPQPNRALAFFLGYGVTFSMAYRLLKSRLYL
NT seq 468 nt   +upstreamnt  +downstreamnt
atggttgacctcactgagctaatggaaaatgaagtattcatggcctttgcttcctataca
acgattattctttcaaaaatgatgtttatgagtactgcaactgcattctttagattgaca
agaaaggtttttgccaacccagaagactgtgcagggtttggcaaaggagaaaatgccaag
aaatatcttcggacagatgacaaagtggaacgtgtgcgaagagctcacctgaatgacctt
gaaaacattgtgccatttcttggtattggccttctgtattccttgagtggtccagatctc
tctacagccatcctgcacttcagactctttgttggagcacggatctaccacacagtcgcg
tatttgacaccccttccccagccaaatcgtgctttggctttctttcttggctatggagtt
actttttcaatggcttacaggttgctaaagagtagattgtacctgtaa

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