KEGG   Prionailurus bengalensis (leopard cat): 122472604
Entry
122472604         CDS       T07574                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X1
  KO
K05459  insulin-like growth factor 1
Organism
pbg  Prionailurus bengalensis (leopard cat)
Pathway
pbg01521  EGFR tyrosine kinase inhibitor resistance
pbg01522  Endocrine resistance
pbg04010  MAPK signaling pathway
pbg04014  Ras signaling pathway
pbg04015  Rap1 signaling pathway
pbg04066  HIF-1 signaling pathway
pbg04068  FoxO signaling pathway
pbg04081  Hormone signaling
pbg04114  Oocyte meiosis
pbg04115  p53 signaling pathway
pbg04150  mTOR signaling pathway
pbg04151  PI3K-Akt signaling pathway
pbg04152  AMPK signaling pathway
pbg04211  Longevity regulating pathway
pbg04213  Longevity regulating pathway - multiple species
pbg04510  Focal adhesion
pbg04518  Integrin signaling
pbg04550  Signaling pathways regulating pluripotency of stem cells
pbg04730  Long-term depression
pbg04750  Inflammatory mediator regulation of TRP channels
pbg04913  Ovarian steroidogenesis
pbg04914  Progesterone-mediated oocyte maturation
pbg04935  Growth hormone synthesis, secretion and action
pbg04960  Aldosterone-regulated sodium reabsorption
pbg05200  Pathways in cancer
pbg05202  Transcriptional misregulation in cancer
pbg05205  Proteoglycans in cancer
pbg05214  Glioma
pbg05215  Prostate cancer
pbg05218  Melanoma
pbg05224  Breast cancer
pbg05410  Hypertrophic cardiomyopathy
pbg05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pbg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    122472604 (IGF1)
   04014 Ras signaling pathway
    122472604 (IGF1)
   04015 Rap1 signaling pathway
    122472604 (IGF1)
   04066 HIF-1 signaling pathway
    122472604 (IGF1)
   04068 FoxO signaling pathway
    122472604 (IGF1)
   04151 PI3K-Akt signaling pathway
    122472604 (IGF1)
   04152 AMPK signaling pathway
    122472604 (IGF1)
   04150 mTOR signaling pathway
    122472604 (IGF1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    122472604 (IGF1)
   04518 Integrin signaling
    122472604 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    122472604 (IGF1)
   04115 p53 signaling pathway
    122472604 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    122472604 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    122472604 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    122472604 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    122472604 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    122472604 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    122472604 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    122472604 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    122472604 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    122472604 (IGF1)
   04213 Longevity regulating pathway - multiple species
    122472604 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122472604 (IGF1)
   05202 Transcriptional misregulation in cancer
    122472604 (IGF1)
   05205 Proteoglycans in cancer
    122472604 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    122472604 (IGF1)
   05218 Melanoma
    122472604 (IGF1)
   05215 Prostate cancer
    122472604 (IGF1)
   05224 Breast cancer
    122472604 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    122472604 (IGF1)
   05414 Dilated cardiomyopathy
    122472604 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    122472604 (IGF1)
   01522 Endocrine resistance
    122472604 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:pbg04052]
    122472604 (IGF1)
Cytokines and neuropeptides [BR:pbg04052]
 Cytokines
  Growth factors (RTK binding)
   122472604 (IGF1)
SSDB
Motif
Pfam: Insulin DUF2865
Other DBs
NCBI-GeneID: 122472604
NCBI-ProteinID: XP_043418277
LinkDB
Position
B4:complement(122721298..122799049)
AA seq 187 aa
MGKISSLPTQLFKCCFCDFLKVKMHIMSPSHLFYLGLCLLTFTSSATAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
VRAQRHTDMPKAQKYHPPSTTKKTKSQRRRKGGPKKHPGGEQKVGTEASQQMKGKKKEQR
RETGARN
NT seq 564 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aaggtaaagatgcacatcatgtccccctctcatctcttctatctgggcctgtgcttgctc
accttcaccagctctgccacagctggaccagagacgctctgtggggctgagttggtggac
gctcttcagttcgtgtgtggagacaggggtttttatttcaacaagcccacggggtatggc
tccagcagtcggagggcacctcagacaggcatcgtggatgagtgctgcttccggagctgt
gatctgaggcggctagagatgtactgtgcacccctcaagcctgccaagtctgcccgctca
gtccgtgcgcagcgccacactgacatgcccaaggctcagaagtatcatcccccatctacc
accaagaaaacgaagtctcagaggagaaggaaaggtgggccaaagaaacacccaggaggg
gagcagaaggtggggacggaagcaagtcagcagatgaaaggaaagaagaaagagcagaga
agggagactggagctagaaactga

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