KEGG   Prionailurus bengalensis (leopard cat): 122472782
Entry
122472782         CDS       T07574                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
pbg  Prionailurus bengalensis (leopard cat)
Pathway
pbg04010  MAPK signaling pathway
pbg04022  cGMP-PKG signaling pathway
pbg04137  Mitophagy - animal
pbg04141  Protein processing in endoplasmic reticulum
pbg04151  PI3K-Akt signaling pathway
pbg04210  Apoptosis
pbg04211  Longevity regulating pathway
pbg04261  Adrenergic signaling in cardiomyocytes
pbg04668  TNF signaling pathway
pbg04720  Long-term potentiation
pbg04722  Neurotrophin signaling pathway
pbg04725  Cholinergic synapse
pbg04728  Dopaminergic synapse
pbg04911  Insulin secretion
pbg04912  GnRH signaling pathway
pbg04915  Estrogen signaling pathway
pbg04918  Thyroid hormone synthesis
pbg04922  Glucagon signaling pathway
pbg04925  Aldosterone synthesis and secretion
pbg04926  Relaxin signaling pathway
pbg04927  Cortisol synthesis and secretion
pbg04928  Parathyroid hormone synthesis, secretion and action
pbg04932  Non-alcoholic fatty liver disease
pbg04934  Cushing syndrome
pbg04935  Growth hormone synthesis, secretion and action
pbg05010  Alzheimer disease
pbg05012  Parkinson disease
pbg05014  Amyotrophic lateral sclerosis
pbg05020  Prion disease
pbg05022  Pathways of neurodegeneration - multiple diseases
pbg05030  Cocaine addiction
pbg05031  Amphetamine addiction
pbg05034  Alcoholism
pbg05161  Hepatitis B
pbg05163  Human cytomegalovirus infection
pbg05166  Human T-cell leukemia virus 1 infection
pbg05203  Viral carcinogenesis
pbg05207  Chemical carcinogenesis - receptor activation
pbg05215  Prostate cancer
pbg05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pbg00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    122472782 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    122472782 (ATF4)
   04668 TNF signaling pathway
    122472782 (ATF4)
   04022 cGMP-PKG signaling pathway
    122472782 (ATF4)
   04151 PI3K-Akt signaling pathway
    122472782 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    122472782 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    122472782 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    122472782 (ATF4)
   04922 Glucagon signaling pathway
    122472782 (ATF4)
   04912 GnRH signaling pathway
    122472782 (ATF4)
   04915 Estrogen signaling pathway
    122472782 (ATF4)
   04926 Relaxin signaling pathway
    122472782 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    122472782 (ATF4)
   04918 Thyroid hormone synthesis
    122472782 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    122472782 (ATF4)
   04925 Aldosterone synthesis and secretion
    122472782 (ATF4)
   04927 Cortisol synthesis and secretion
    122472782 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    122472782 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    122472782 (ATF4)
   04728 Dopaminergic synapse
    122472782 (ATF4)
   04720 Long-term potentiation
    122472782 (ATF4)
   04722 Neurotrophin signaling pathway
    122472782 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    122472782 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    122472782 (ATF4)
   05203 Viral carcinogenesis
    122472782 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    122472782 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    122472782 (ATF4)
   05161 Hepatitis B
    122472782 (ATF4)
   05163 Human cytomegalovirus infection
    122472782 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    122472782 (ATF4)
   05012 Parkinson disease
    122472782 (ATF4)
   05014 Amyotrophic lateral sclerosis
    122472782 (ATF4)
   05020 Prion disease
    122472782 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    122472782 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    122472782 (ATF4)
   05031 Amphetamine addiction
    122472782 (ATF4)
   05034 Alcoholism
    122472782 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    122472782 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    122472782 (ATF4)
   04934 Cushing syndrome
    122472782 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:pbg03000]
    122472782 (ATF4)
Transcription factors [BR:pbg03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    122472782 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 DUF4407 MCU KIF21A Asd-4 AAA_13 Nop53 bZIP_Maf DUF3450 Laminin_II OVT1
Other DBs
NCBI-GeneID: 122472782
NCBI-ProteinID: XP_043418591
LinkDB
Position
B4:132953431..132955601
AA seq 352 aa
MAEMMNFLSSEVLGGDLMSPFDQSGLGAEVSLGLLDDYLEVAKHFKPHGFSSDKAKAGSS
EWLAVDGLVSASDNGKEDAFSGTDWMVEKMDLKEFDFDSLFNIDDLETMPDELLATLDDT
CDLFDPLVQETNKEPPQTMNPIGHLPENLPKTDQVAPFTFLQPLSLSPGALSSTPDHSFS
LELGSEVDISEGDRKPDSTAYILMIPQCIKEEDAPSDNDSGICMSPESYLGSPQHSPSAS
RGSPSKSQLSPCSLCGSARPKPYDPPGEKTAAKVKVEKLDKKLKKMEQNKTAATRYRQKK
RAEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKAREKKRVP
NT seq 1059 nt   +upstreamnt  +downstreamnt
atggccgagatgatgaacttcctgagcagcgaggtgttggggggggacttgatgtccccc
ttcgaccagtcgggtttgggggctgaagtaagcctaggtctcttagacgattacctggag
gtggccaagcacttcaaacctcatgggttctccagcgacaaggctaaggcgggctcctcc
gaatggctggctgtggatgggttggtcagtgcctcagacaacggcaaggaggatgccttc
tccgggacagattggatggtggagaaaatggatctgaaggagtttgattttgattctctg
ttcaatatagatgacctggaaaccatgccagatgagcttttggccactttggatgacaca
tgtgatctctttgaccccctagtccaggagacgaataaggagcccccccagaccatgaac
ccaattggccatctcccagaaaatttacccaaaacagaccaggttgccccttttaccttc
ctgcaacctctttctctctccccaggggccctatcctccactccagatcattcttttagt
ttagagctaggcagtgaggtggatatctctgaaggagatagaaagccagactctactgct
tacattctcatgatccctcagtgcataaaggaggaggatgccccctcagataatgatagt
ggcatctgtatgagtcctgagtcctacctggggtccccccagcatagcccctcggcttcg
aggggctctccaagtaagagccagctgtctccatgttccctctgtggttctgcccgcccc
aaaccctacgatcctcctggagagaaaacggcagcaaaagtaaaggtggagaagttggat
aagaagctgaaaaaaatggagcagaacaagacagcagccactaggtaccgccagaagaag
agggcggagcaagaggcccttactggcgagtgtaaagagctagaaaagaagaacgaggct
ctgaaagagagggcagactctttggccaaggagatacagtatctgaaagatttgatagaa
gaggtccgaaaggccagggagaagaaaagggtcccctag

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