Prionailurus bengalensis (leopard cat): 122473017
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Entry
122473017 CDS
T07574
Symbol
PDE3A
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase A
KO
K19021
cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:
3.1.4.17
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg00230
Purine metabolism
pbg01100
Metabolic pathways
pbg04022
cGMP-PKG signaling pathway
pbg04024
cAMP signaling pathway
pbg04924
Renin secretion
pbg05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
122473017 (PDE3A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
122473017 (PDE3A)
04022 cGMP-PKG signaling pathway
122473017 (PDE3A)
09150 Organismal Systems
09152 Endocrine system
04924 Renin secretion
122473017 (PDE3A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
122473017 (PDE3A)
Enzymes [BR:
pbg01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
122473017 (PDE3A)
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Motif
Pfam:
PDEase_I
Motif
Other DBs
NCBI-GeneID:
122473017
NCBI-ProteinID:
XP_043419066
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Position
B4:53392642..53704687
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AA seq
1144 aa
AA seq
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MAVPREAARVRDKPGHGGVHPAPAAGRDYPARPGAAPPRDSGSRGRWRDLVLQPLRRSRK
LSSALCAGSLSFLLALLVRLVRGEIGRDPEQSKEVAAAAAEEAALGAEGGVFPGLRGGAP
GGGAPLSPWLQPSALLFSLLCAFFWMGLYLLRAGVRLPLAVSLLAACCGGEALVQIGLGV
GEDHLLSLPAAGVVLSCLAAATWLVLRLRLGVLMIALTSAVRTVSLISLERFKVAWRPYL
AYLAGVLGLLLARYVEQILPQPAGAAPREHFGSQLIAGTREDIPVFKRRRRSSSVVSAEM
SGCSSKSHRRTSLPCIPREQLMGHSEWDHKRGPRGSQSSGTSITVDIAVMGEAHGLITDL
LADPSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRVNPVISFSENYTCSDSEESSEKDKLA
IPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKLHEASSSSAVCPD
SWNNPVMMTLTKSRSFTSSYAVSAANHVNSKKPNRPGALAKISPLSSPCSSPPQGTPASS
PVSKISAVQFPESANTAAKQGLSSHRALTYTQSAPDLSPQILPPPVICSSCGRPYPQGTP
AAVPLERSSATIRTPSRMDDTTQVTSDYETNNNSDSSDIVQNEDETECPREPLRKASACG
TYTSETMIFLDKPVLAPEPLVMDNLDSIMEQLNTWNFPIFDLVEKIGRKCGRILSQVSYR
LFEDMGLFEAFKIPVREFMNYFHALEIGYREIPYHNRIHATDVLHAVWYLTTQPIPGHST
VINDHGSASDSDSDSGFTHGHMGYVFSKMYNVPDDKYGCLSGNIPALELMALYVAAAMHD
YDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHF
RFLVIEAILATDLKKHFDFVAKFNAKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKC
KELHLQWTEGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYD
SAGLMPGKWVEDSDESGDTDDPEEEEEEEEAPNEEETCENNEAPRKKTFKRRKIYCQITQ
HLLQNHKMWKKVIEEEQRLAGIESQSLDQSPQQHSSEQIQAIREEEEEKGKPRGEEIPTL
KQNQ
NT seq
3435 nt
NT seq
+upstream
nt +downstream
nt
atggcagtgccccgcgaggccgcccgagtccgagacaagccaggccacggtggggtgcat
ccagcccccgccgcgggccgggactaccccgctcgccccggcgccgcaccgccgcgggac
tccggcagccgcggccgctggagagacctggtgctgcagccgctccggcgctcccggaaa
ctttcctcagcgctgtgcgccggctccctgtcctttctgctggccctgctggtgaggctg
gtgcgcggggagatcggccgggacccggagcagagtaaggaggtggcggctgcggcggcg
gaggaagcggccctgggagcagaagggggcgtcttcccggggcttcggggaggtgctccc
gggggcggcgcgccgctcagcccctggttgcagccctcggcgctgctcttcagtctcctg
tgtgccttcttctggatgggcttgtacctcctgcgcgccggggtgcgcctgcctctggcc
gtctcactgctggcagcctgctgcgggggggaagctcttgtccagattgggctgggcgtc
ggggaggatcacttactctcgctcccggccgcgggggtggtgctcagctgcttggccgcc
gcgacatggctggtgctgaggctgaggctgggcgtcctcatgatcgccttgactagcgcg
gtcaggaccgtgtccctcatttccttagagaggttcaaggtcgcctggagaccttacctg
gcgtacttggccggcgtgctggggctcctcctggccaggtacgtggagcaaatcttgccg
cagcccgcgggggcggctccgagggagcatttcgggtcccagctgattgctgggaccagg
gaagatatcccagtatttaagaggaggaggcggtccagttccgtggtgtccgccgagatg
tccggctgcagcagcaagtctcatcggaggacctccctaccctgcataccgagggaacag
ctcatgggacattcagaatgggaccacaagcgagggccaagaggatcacagtcttcagga
accagtattactgtggatattgccgtgatgggtgaagctcatggtctcattaccgacctc
ctggcagacccttctctgccccccaacgtgtgcacatccttgagggctgtgagcaacctg
ctcagcacccagctcaccttccaggctattcacaagccccgcgtgaatcctgttatttcc
ttcagtgaaaactacacctgttctgattctgaagaaagctctgaaaaagacaagctggct
attcccaagcgtctgagaaggagtttgcctcctggtttgttgagacgtgtttcatcaact
tggacaaccaccacctcagccacaggcctacccactttggagcctgccccagtccggagg
gaccgtagtgccagcatcaaactgcatgaagcatcttcatcaagtgctgtttgtcctgat
tcttggaataacccagtgatgatgaccctcaccaaaagcagatccttcacttcgtcctat
gctgtttctgcagctaaccatgtaaactcaaaaaagccaaatcgaccaggtgccctagct
aaaatttcacctctttcgtcgccctgttcctcacctccccaagggacccccgccagcagc
ccagtcagcaaaatttctgcagtgcagtttccagaatctgccaacacagctgccaaacag
ggcctaagttctcacagggcattaacttatactcagagtgcccctgacctatctcctcag
atcctccctccacctgttatatgtagcagctgtggcaggccatatccccaagggacccct
gctgctgtgcccctggagagaagcagtgccaccattcggacaccaagcagaatggatgac
actactcaagttacctctgattatgaaaccaataacaacagcgatagcagtgatattgta
cagaatgaagatgagaccgagtgcccgagagagcctctaaggaaagcttcggcttgtggc
acctacacgtctgagaccatgatattcctggacaaaccagttcttgctcctgaacctctg
gtcatggataatttggactcaattatggagcagctaaatacttggaattttccgattttt
gatttggtggaaaaaataggaagaaaatgtggccgtattcttagccaggtatcatacaga
ctttttgaagacatgggcctctttgaagctttcaaaattccagttagggaatttatgaat
tattttcatgctttggagatcggatacagggaaattccttatcataacagaatccatgcc
actgacgtcttacatgctgtttggtatcttactacacaacctattccaggccactcaact
gtgattaatgatcacggatcagcaagtgattcagattctgacagtgggtttacacatgga
catatgggatatgtattctcaaaaatgtataatgtgcctgatgataaatacggatgtctc
tctggaaatatccctgccttagagttaatggccctgtatgtagctgcagccatgcatgat
tatgatcacccaggaaggactaatgctttcctggttgcaactagtgctcctcaggcggtg
ctctataatgatcgttcagttttggagaaccatcatgcagctgctgcatggaatcttttc
atgtcccggccagagtacaacttcttagttaatcttgaccatgtggaatttaagcatttt
cgtttcctcgtcattgaagcaattttggccactgacctgaagaaacactttgatttcgta
gccaaatttaatgccaaggttaatgatgatgttggaatagattggaccaatgaaaatgat
cgtctactggtttgtcaaatgtgtataaagttggctgatatcaatgggccagctaaatgt
aaagagctccatctccagtggacagagggtattgtcaacgaattttatgaacagggtgat
gaagaggccagccttgggttaccaataagccccttcatggaccgttctgctcctcagctg
gccaatcttcaggaatccttcatctctcacattgtgggtcctctgtgcaactcctatgat
tcagcaggactaatgccagggaaatgggtggaagacagtgatgagtcaggagatactgat
gacccagaagaagaggaggaggaggaggaagcaccaaatgaagaggaaacctgtgaaaat
aatgaagctccaagaaagaaaactttcaaaaggaggaaaatctactgccaaataactcaa
cacctcctgcagaaccacaagatgtggaagaaagtcattgaagaggaacagcggttggcg
ggcatagagagtcaatccctggaccagtcaccccaacagcattcctcagaacagatccag
gccatcagggaagaagaggaagagaaagggaagccaagaggagaggagatcccaaccctg
aagcaaaaccagtga
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