Prionailurus bengalensis (leopard cat): 122473944
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Entry
122473944 CDS
T07574
Symbol
TBK1
Name
(RefSeq) serine/threonine-protein kinase TBK1 isoform X1
KO
K05410
TANK-binding kinase 1 [EC:
2.7.11.10
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg04014
Ras signaling pathway
pbg04137
Mitophagy - animal
pbg04140
Autophagy - animal
pbg04620
Toll-like receptor signaling pathway
pbg04621
NOD-like receptor signaling pathway
pbg04622
RIG-I-like receptor signaling pathway
pbg04623
Cytosolic DNA-sensing pathway
pbg04657
IL-17 signaling pathway
pbg04936
Alcoholic liver disease
pbg05014
Amyotrophic lateral sclerosis
pbg05022
Pathways of neurodegeneration - multiple diseases
pbg05135
Yersinia infection
pbg05160
Hepatitis C
pbg05161
Hepatitis B
pbg05162
Measles
pbg05163
Human cytomegalovirus infection
pbg05164
Influenza A
pbg05165
Human papillomavirus infection
pbg05167
Kaposi sarcoma-associated herpesvirus infection
pbg05168
Herpes simplex virus 1 infection
pbg05169
Epstein-Barr virus infection
pbg05170
Human immunodeficiency virus 1 infection
pbg05171
Coronavirus disease - COVID-19
pbg05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
122473944 (TBK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
122473944 (TBK1)
04137 Mitophagy - animal
122473944 (TBK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
122473944 (TBK1)
04621 NOD-like receptor signaling pathway
122473944 (TBK1)
04622 RIG-I-like receptor signaling pathway
122473944 (TBK1)
04623 Cytosolic DNA-sensing pathway
122473944 (TBK1)
04657 IL-17 signaling pathway
122473944 (TBK1)
09160 Human Diseases
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
122473944 (TBK1)
05161 Hepatitis B
122473944 (TBK1)
05160 Hepatitis C
122473944 (TBK1)
05171 Coronavirus disease - COVID-19
122473944 (TBK1)
05164 Influenza A
122473944 (TBK1)
05162 Measles
122473944 (TBK1)
05168 Herpes simplex virus 1 infection
122473944 (TBK1)
05163 Human cytomegalovirus infection
122473944 (TBK1)
05167 Kaposi sarcoma-associated herpesvirus infection
122473944 (TBK1)
05169 Epstein-Barr virus infection
122473944 (TBK1)
05165 Human papillomavirus infection
122473944 (TBK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
122473944 (TBK1)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
122473944 (TBK1)
05022 Pathways of neurodegeneration - multiple diseases
122473944 (TBK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
122473944 (TBK1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
122473944 (TBK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pbg01001
]
122473944 (TBK1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pbg04131
]
122473944 (TBK1)
Enzymes [BR:
pbg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
122473944 (TBK1)
Protein kinases [BR:
pbg01001
]
Serine/threonine kinases: Other
IKK family [OT]
122473944 (TBK1)
Membrane trafficking [BR:
pbg04131
]
Autophagy
Xenophagy
Other xenophagy associated proteins
122473944 (TBK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TBK1_CCD1
Pkinase
TBK1_ULD
PK_Tyr_Ser-Thr
Pkinase_fungal
ABC1
Kinase-like
DUF713
CEP63
COG6_N
Motif
Other DBs
NCBI-GeneID:
122473944
NCBI-ProteinID:
XP_043420742
LinkDB
All DBs
Position
B4:89672135..89725605
Genome browser
AA seq
729 aa
AA seq
DB search
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPISCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMIIHVFSLQQMTAHKIYIHSYNTATVFHELVYKQTKIISSNQELIYEGRRLV
IEPGRLAQHFPKTTEENPIFVVSREPLSTIGLIYEKISLPKVHPRYDLDGDASMAKAITG
VVCYACKIANTLLLYQELMRKGIRWLIELVKDDYNETVHKKTEVVITLDFCIRNIEKTVK
VYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIESRLSPGGLLADMWAHQE
GTHPKDRHVEKLQVLLNCITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTH
FTDECVKKYEAFLDKSEEWMRKMLHLRKQLLSLTNQCFDIEEEVSKYQDYTNELQETLPQ
KMFAASSGIKHTMTPIYPCSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMD
GGLRNVDCL
NT seq
2190 nt
NT seq
+upstream
nt +downstream
nt
atgcagagcacctctaatcatctgtggcttttgtctgatattttaggccaaggagctact
gcaaatgtctttcgtggaaggcataagaaaactggtgacttatttgctatcaaagtattt
aataacataagcttccttcgtccagtggatgttcaaatgagagaatttgaagtgttaaaa
aaactcaatcacaaaaatattgtcaaattatttgctattgaagaggagacaacaacaaga
cataaagtacttattatggaattttgtccatgcggaagtttatacactgttttagaagag
ccatctaatgcctatggactaccagagtctgaatttttaattgttttgcgagacgtggtg
ggtggaatgaaccatctacgagagaatggcatagtgcaccgtgatatcaagccaggaaac
atcatgcgtgttataggggaagatggacagtctgtgtacaaactcacagattttggtgca
gctagagaattagaagatgatgaacagtttgtttctttgtatggcacagaagaatatttg
catcctgatatgtatgagagagcagtgctaagaaaagatcatcagaagaaatacggagca
acagttgatctttggagcattggggtaacgttttaccatgcagctactggatcactgccg
ttcagaccatttgaagggccacgtaggaataaggaagtgatgtataaaataattactgga
aagccttctggggcaatatctggagtacagaaagcagaaaatggacccatcgactggagt
ggagacatgcctatttcttgcagtctttctcggggtcttcaagttctacttacccctgtt
cttgcaaacatccttgaggcagatcaggaaaagtgttggggttttgaccagttttttgca
gaaactagtgatatacttcatcggatgataattcatgttttttcactgcaacaaatgaca
gcccataagatttatattcatagctacaatactgctactgtatttcatgaactggtatat
aaacaaaccaaaattatttcttcaaatcaagaacttatatatgaagggcgacgtttagtt
atagaacctggaagactggcacagcattttcctaaaactactgaggaaaatcccatcttt
gtagtgagtcgggaacctctgagtaccataggattgatatatgagaaaatttcccttcct
aaagtacatccacgttacgatttagatggggatgctagcatggctaaggcaataacagga
gttgtatgttatgcttgtaaaattgccaataccttgctgctttatcaggaattaatgcga
aaggggatacgatggttgatagaattagttaaagatgattataatgaaactgttcacaaa
aagacagaagttgtgatcacactggatttctgcatcagaaacattgaaaaaactgtgaaa
gtatacgaaaagttgatgaagatcaacctagaagcagcagagttaggtgaaatttcagac
atacacaccaaattgttgagactttccagttctcagggaacaatagaaaccagtcttcag
gatatcgaaagcagattatctccaggtggattgttggcagacatgtgggcccatcaagaa
ggcactcatccaaaagatagacatgtagaaaagctacaagtcctgctaaattgcatcaca
gagatttactatcagttcaaaaaagacaaagcagaacgtagactagcttataatgaagaa
cagatccacaaatttgataagcaaaaactgtattaccatgcaacaaaagctatgacccat
tttacagacgaatgtgttaaaaaatatgaggcatttttggataagtcagaagaatggatg
agaaagatgcttcatcttaggaaacagttattatcactaactaatcagtgttttgatatt
gaagaagaagtgtcgaagtatcaagattatacaaatgagttacaagaaactttgcctcaa
aaaatgtttgcagcctccagtggaatcaaacataccatgaccccaatttatccatgttct
aatacattagtggaaatgactcttggtatgaagaaattaaaggaagagatggaaggagtg
gttaaagaacttgctgaaaataatcatattttagaaaggtttggctctttaaccatggat
ggcggccttcgcaatgttgactgtctttag
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