Prionailurus bengalensis (leopard cat): 122474798
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Entry
122474798 CDS
T07574
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg00790
Folate biosynthesis
pbg01100
Metabolic pathways
pbg01240
Biosynthesis of cofactors
pbg01523
Antifolate resistance
pbg04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
122474798 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
122474798 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
122474798 (FPGS)
Enzymes [BR:
pbg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
122474798 (FPGS)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
122474798
NCBI-ProteinID:
XP_043421877
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Position
D4:86542181..86551818
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AA seq
580 aa
AA seq
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MSQARRHLRPALFLVAVSARVATTGVAARRGLSAWPAPQEPGMEYQDAVRALNTLQTNAG
YLEQVKRQRGDPQAQLEAMKLYLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTERILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWPLYHRLEETKDSSSYVSMPAYFR
FLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPAVCGISSLGIDHTSILGDTVEEI
AWQKGGIFKRGVPAFTVLQPDGPLAVLRDRAQQISCPLYLCPPLEALEEGGPPLTLGLEG
EHQRSNAALALQLARCWLQQKHYRGIGELKVSRPSLLRQMPLAPVFQPTTHMRHGLRDTE
WLGRTQVLRRGPLTWYLDGAHTASSMQACVRWFRQALHRRQRPSRGSEVFVLLFNSTGDR
DPAALLKLLQPCQFDYAVFCPNLTEVSTVGNADQQNFMVTLDQVLLRCLAHQQHWSRLDE
EQAGPEPGEPTSSLLAPHPPEPRSTSSLVFSCISHALLWISQGRDPVFHPPSPPQGLFAH
PVAGSGAGVLREAAAIHVLVTGSLHLVGGVLKLLEPALSQ
NT seq
1743 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcaggcacgccgccacctgcgacccgctcttttcctggtggcggtttctgcgcgc
gttgcaactaccggggtagcggctcggcgagggttgagcgcgtggcccgcgccgcaggag
cccggcatggagtatcaggacgctgtgcgcgcactgaacaccctgcagaccaatgctggc
tatctggagcaggtaaagcgccagcggggtgaccctcaggcacagctggaagccatgaag
ctgtacttggcacggagtgggctgcaggtggaagacttggaccagctgaacatcattcac
gtcactgggaccaaggggaagggttccacttgtgcctttactgaacgtattctccgaagc
tatggcctgaagacaggattctttagctctccccacctggtgcaggtgcgggagcggatc
cgcatcaacgggcagcccataagccctgagctcttcaccaagcacttctggcccctctac
caccggctggaggagaccaaggacagcagcagctatgtctccatgcccgcctacttccgc
ttcctcacgctcatggccttccacgtcttcctccaagagaaggtggacctggcagtggtg
gaggtgggcattggtggcgcttacgactgcaccaacatcatcaggaagcctgcggtgtgt
ggcatctcctctcttggcatcgaccacaccagcattctgggggacacagtggaggagatc
gcgtggcagaaagggggcatcttcaagcgtggcgtccccgccttcaccgtgctccagcct
gacggtcccctggccgtgctgagggaccgggcccagcagatctcgtgtcctctctacctg
tgcccaccactggaagccctggaggaagggggaccgccgctgaccctgggcctggaggga
gagcaccagcggtccaatgccgccttggccttgcagctggctcgctgctggctacagcaa
aagcactaccggggcatcggggagctgaaggtgtccaggcccagtctcttgcggcagatg
cccctggcgcccgtgttccagcccacgacccacatgcggcatgggcttcgggacacggag
tggctgggccggacgcaggtgctgcggcgcgggcccctcacctggtacctggatggcgcg
cacaccgccagcagcatgcaggcctgcgtgcgctggttccgccaggcgctgcaccgccgc
cagaggccaagccgcggctctgaggtgtttgtcctgcttttcaactccaccggagaccgg
gatcctgcagcactgctgaagctgctgcagccctgtcagtttgactatgctgttttctgc
cctaacctgacagaggtctcaactgttggcaatgcagaccagcagaacttcatggtgacc
ctggaccaggtgttgctccgctgccttgcacaccaacagcactggagccgcctggacgag
gagcaggccggcccggagcctggtgagcccacatcctcgctgctggctccccacccgccc
gagccccgtagcaccagctccctcgtcttcagctgtatctcccacgccttgctgtggatc
agtcaaggccgggaccctgtcttccacccacccagtcccccgcagggcctcttcgcccac
cctgtggcaggcagcggggccggcgtgctccgtgaggctgccgccatccacgtgctggtc
accggcagcctgcacctggtgggcggcgtcctgaagctgctggagccggccctatcccag
tag
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