Prionailurus bengalensis (leopard cat): 122474886
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Entry
122474886 CDS
T07574
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
122474886 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
pbg03021
]
122474886 (SETX)
Enzymes [BR:
pbg01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
122474886 (SETX)
5.6.2.5 RNA 5'-3' helicase
122474886 (SETX)
Transcription machinery [BR:
pbg03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
122474886 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
ResIII
SLFN-g3_helicase
NAT10_TcmA_helicase
AAA_16
nSTAND3
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
122474886
NCBI-ProteinID:
XP_043422152
LinkDB
All DBs
Position
D4:complement(90178875..90244276)
Genome browser
AA seq
2669 aa
AA seq
DB search
MSTCCWCTPGGISTADFLKRYASRTHAGEFQTADEDLCYCLECVAEYHKARDDLPFLHEV
LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEAQLFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLEDPDIYTSSVLEKGKLILLPSHMYDTTNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQADDDSVDPFWPALHCFMVILDRL
GSKVWGQRIDPIEAFQTIINNMSYNREIQNIRSSSVRTKSEPESYLDDTVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLHSEVKDVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFARSSEKSSGNCSKGAAVISSLSLHSMPSNSVQLACVQLIR
SLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTTQETHELQTCLKQIIRNVKFKVP
QCSTFVDLTPVCKTPPASYNKEESEQTGKKSKKGLHCLENSSPTFSKGPMKAEAFQMPEN
RLVKASNASEEDSEHNYIKDLKLEGRLSAESCIKQGSKRLVPEGAQDAVKTSKGKQKSVK
EDPTDSRNGPERGCDRGVIIAARSLTDSGTDSLEKASTSTEDFSLKGDVLGKTSKGKPKG
QKAEICAKLSHVIKKQHRKSTLIDDGNLEEKLTVSTIDSFFSRKDSGGQKGDGFINHLSL
DPDDVPDDKNGERKSQNSLLLKKKQFKSKELDIFSSRENSCQIQECQAEGKDLVSFTEVT
DTCVKKTSPFKDPVTLLESRDKEVGKSTTSQVSSHLREQVPSLSPQSSTLTDSQIDRDLH
NLSLIAQASVIKFPSESTQKSSSQLQRKVKDKRCFTANLSNAGEACRGQVIVISDSDDDD
GDEGILGFEKHIKRDKIGIKKEYPEEHTSVASTSVEQKLIKEEEAKSLLEFEESDSQFFE
FESPHEVFSVWQDQEPDNKNSVQEDENNSRLTHVNDVMSDWGYDTDYVSEEVIKKVAEGI
EKHTEPQSGSSVGEFCETEVKKRKRKRHEKPAAEDPLRPSPSERNEDQSDNERGLTENDL
KSIELRSRSRSNLQRGTTDSLKKSSPKLRTYSKPVRRVPHSKTKKTHSDTKKGQNKSSNY
ISCRTTPAIVPPKILRQCPEPTSTVEKLGLKKAPRRAFDLSQRSLGYLVQLRDHGKTVGV
VDTRKKTKLISPQTLSVRNNKKLLTSQDLQSRRQAKHKSKQKRQGSLGSESRAPTRAGLR
SAQNPDTLVPESDSSDCRAKGGAEVGANNTGKPSIKRASSEPEPVKTKRVSQVADDPCLS
SQCASVVLNGRKATHEAIVSTSADPLGGGDLTEHRLELTALKEGEPRSNSDSEDENIFLT
QHDPADMDLCSQMENGNQKLIEIVHGKDTALMEEESWSSTKCKYKDCVEAAQNQGEYCSK
HCEAKAVDEDVFRKPGLPPSASKRPSTAKVFSSSSTSRIANLSKSLESTSAPPPALKQKS
NGVPAVLKVPQPASVLSPKPVGEVKSLSDVLRPQTLNNSNRQGYKLTFGESRSFSASSAV
NVLLSSQSISDTFVKEVLKWKYEMFVNFDQCGPPTSLCQSISRPVPVRFQDCGDYFNVFF
PLMILNTFETVAQEWISSPNKEKFYQLHVRKFPADYKKYWEFVVLLEECELTKQLHPKEN
DLVFLVLEKQNGEKKNTERNRMPDLHEYHCGYVHKFRRTSVMRNGKSECSLSIQTQDNLP
LSLNELVKCTVISSLVTTQRKLKAMSLLSGRNQLARAVLNPNPMDFCTKDLLTTTSERII
AYLKDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRKG
RSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGP
EKSINNEVLRFSLDSQVNHRMKKDLPSHVQEMHRRKEFLDHQLDELSRQRALCRGGKETQ
RQELDEKIAKVSKERQELASKIKEVQGRPQKTQSIIILESHVICCTLSTSGGLLLESAFR
GQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQS
MMARFCKLLEDSVEHNVIGRLPVLQLTVQYRMHPDICLFPSNYVYNRSLKTNRLTETNRC
SSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRRDVTFRNIGIITHY
KAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANALQGSIGFLASLQRL
NVTITRAKYSLFILGHLRTLMENQHWNHLIQDAQKRGAIVKTCDKNYRHDAAKILKLKPV
LQRSLTHPPTVAPEVARPQGGLPGSKPDGEFAKTSFPSSLYHVPSGCKESTGAVTTKDPE
RPPIQDRLRDPRLLRRLGIDPEAKGTCPRDPQPLSPQHPGATPPSGEPGFPLSHQDLGGA
QLSTARGTTLSTQNPPVQWEPPAAGTDVSASKRACDWEGGLSRRRETRAFSEGDRETQSP
ESRHPKRRSGWDNRRLEEEDSGSKRRKFL
NT seq
8010 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgtacgcccggtggtatttccaccgctgacttcctcaagcgc
tatgcgtccaggacccacgccggggaatttcagacagccgacgaagacctctgctactgc
ctggagtgtgtggccgagtaccacaaagcacgcgacgacctgcccttcctgcatgaggtt
ttgtgggaattagaaaccttacgtctcataaatcattttgaaaaatccatgaaggcagaa
attggagatgatgatgaattgtacatagtagacaacaatggagaggcacagctgtttgac
ttcactggccaagactttgaaaataagcttcgagttcctcttcttgaaatcctgaagtat
ccgtatctgcttttacacgagcgtgttaacgaattatgtgttgaagcactttgtcggatg
gaacaagctaattgctcctttcaggtttttgacaaacatccaggcatttatttgtttctg
gtccatcccaatgaaatggttcggcgttgggctatcctgaccgcaaggaacttgggaaaa
gtggacagagatgattattatgatctgcaggaggttttgacttgtctttttaaagtcatt
gagttggggcttctggaagatccagacatctacacttcttctgtcctcgagaagggtaaa
ctgattcttctgccttcgcacatgtacgataccaccaactacaagaactattggctaggt
atttgcatgttgctgaccattcttgaggagcaggctatggactccctgttgctgggctca
gacaaacagaatgatttcatgcaatcaatacttcacaccatggagaggcaagcagatgat
gatagcgtggatcctttctggccagcattacactgtttcatggtgattctggatcgcctc
ggatcaaaggtctggggtcaacgcatcgatcctattgaggcgtttcagactattatcaat
aacatgagctacaatagagagatccaaaatatacggagcagctctgtaaggaccaagtcg
gaaccggagtcgtatttggatgatacagtgacttgtagccagatcgtgtacaattacaac
cctgaaaagaccaaaaaggattctgggtggagatcagccatttgcccagattactgtcct
aacatgtacgaagagatggaaacgttagccagtgtgcttcagtcagatattggtcaagac
atgcgtgttcacaatagcacgtttctgtggttcatcccctttgttcagtccctcatggat
cttaaggatttgggtgtggcttacatagtagaggtgattcaccatctgcactctgaagtc
aaagatgtcctcaaccaaacagatgctgtgtgtgacaaagttactgagtttttccttctg
attttggtgtccgtgattgaactgcacagaaataaaaaatgtttgcacttgctgtgggtt
agttcccagcagtgggtggaggctgttgtaaaatgcgccaagcttcccaccaccgcgttt
gcacggagttctgagaagtcatctggaaattgctccaaaggagcagcagtgatatcgtct
ctgtcactgcattcgatgccgtcgaattctgtccagctggcttgtgtgcagctgatcaga
agtctccttaaagaagggtatcagcttgggcagcagactctgtgcaagcgattctgggac
aagctcaacttatttctgcgtgggaatttatctctaggttggcagttgactactcaggaa
acccatgagttacaaacttgtttaaagcaaattattagaaacgtaaaattcaaagtacct
cagtgtagcacttttgtggatctgacccccgtatgtaaaacccctcctgcgtcttacaat
aaagaagaaagtgaacagacagggaagaaatctaaaaaaggcctgcactgtctggaaaac
tccagcccaacattttctaaaggaccaatgaaagctgaggcatttcagatgccagagaat
agattggtcaaagcaagtaacgctagcgaagaggatagtgagcacaattacataaaagat
ttgaaactagaaggccgtctctcagcagagtcatgcataaagcagggtagcaaaaggctt
gtcccggaaggagctcaagatgcagtcaaaacaagtaaagggaagcagaagtctgtgaag
gaggatcctacggattccagaaatggtccggaaaggggatgtgacagaggggtgataata
gccgcacgttcgttgactgattctggcaccgactccctggagaaggcgtccacgtcaact
gaggatttctctttgaagggtgatgttcttggcaaaacctcaaaaggaaaacctaaggga
cagaaagctgaaatctgtgctaagttatcacatgtaataaagaagcaacacaggaaaagt
actttgatcgatgatggcaatttagaggaaaagctgactgtgtctaccattgacagtttc
ttttcaaggaaagattcaggaggtcagaaaggggatggcttcataaaccatctctcttta
gaccctgatgacgttcccgatgataaaaacggggagcgaaaatctcaaaacagtttattg
ctgaagaagaaacaattcaagagcaaagagttagatattttctcttcccgtgaaaatagc
tgtcaaatacaggaatgccaagcagaaggtaaagatttggtctcgtttacggaagtgacc
gatacttgtgtgaagaaaacgtctcccttcaaagaccccgtgactcttcttgaatcgaga
gataaggaagttggcaagagtaccaccagtcaggtgtcttctcacttgagggaacaggtt
cctagcctcagtccacagtccagcaccttgacagattcccagatagaccgagacctccac
aacttatctttgatagcccaagccagtgttattaagtttccatcagagtcaactcaaaaa
agctcatcccagctacaaagaaaagtaaaagataaaagatgtttcacggctaacctgagt
aatgctggagaagcctgccggggccaggtgattgttatttcagattctgatgatgatgat
ggtgatgaagggattctgggttttgagaaacacattaaacgagataaaataggcatcaag
aaagaatatcctgaggagcatacttcagtagctagtacaagtgtggaacagaagctaata
aaggaagaagaggcaaagtccctattggagtttgaggaatcggattctcagttttttgag
tttgaaagtccacatgaggtgttttcagtttggcaagatcaggaaccagacaacaagaat
tcagttcaagaggatgaaaacaattcacgtctgactcacgtaaacgatgtcatgagtgat
tggggttacgatacggattatgtatctgaagaggttattaagaaagtagcagagggcatt
gaaaaacacacagaaccacagagtggtagttctgtcggggaattttgtgaaactgaagtg
aaaaaacgtaagagaaaacgacatgaaaaacctgcagctgaagatcctctgaggccttca
ccttctgagagaaacgaggaccagtctgataatgagagaggtctgactgaaaatgatctt
aaaagtatagagctgaggtcaaggtccaggtcgaatcttcaaagaggcactacagattca
ctaaagaagtcttctccaaagcttcgtacttactccaaacccgttaggagagtcccgcat
tctaaaactaagaaaacacattcagataccaaaaaagggcagaataaaagttcgaattac
ataagttgtaggacgactcctgctatagtcccaccaaagatacttcgccagtgccctgaa
ccaacttcaaccgttgaaaaacttggtctgaaaaaggctcctcgtagggcattcgattta
tctcagcgatctctagggtatttagttcagttacgggaccatggcaaaaccgtgggagtg
gttgataccagaaaaaagactaaattaatttctcctcagactctctctgtcagaaataat
aagaaactgttgacaagtcaagatcttcagtcgcgaaggcaggcgaaacacaaatcaaag
cagaagaggcaaggctctctgggttctgaaagcagagctcctacaagagcagggctgcgt
tcagcacagaatcctgacactctcgtcccagaatccgatagctcagattgtcgtgctaaa
ggaggcgccgaggtgggtgctaacaatactggaaagccatcaataaaacgcgcgtcttct
gaaccagaacccgtgaaaacgaaacgtgtttctcaggtggctgatgatccttgcctttcg
agccagtgcgcttctgttgtgttaaatggaagaaaagcaacacatgaagccattgtctct
acgtcagctgaccctttaggtggaggcgacctaacagaacatcgtttagagttgaccgct
ctgaaagagggagagcccagatccaacagtgactcggaagatgagaatatatttctaacc
cagcacgatcccgcagatatggatttatgttcacaaatggaaaatgggaaccagaaactc
attgaaatagttcatggaaaagatacagctctgatggaagaagaatcttggagcagcaca
aaatgtaagtacaaggattgtgtcgaagccgcgcaaaaccagggtgaatactgctccaaa
cactgcgaagctaaagcagtggatgaagatgtgtttcgtaaaccgggcttgcccccctct
gcgtccaagagaccctccactgccaaggtctttagctcaagtagtacttcacgaattgct
aatctttcgaagtctttggaaagtacctccgcaccgccaccggccctcaaacagaagtca
aacggggtaccagctgttttgaaagtcccacagccagcctctgtgttgtctccaaagcca
gtgggtgaggtgaagagtttgtctgatgttctccgtcctcagactctgaataattccaac
aggcaaggttacaagcttacctttggcgaaagcagatctttttcggcttcctctgcggta
aacgttctcttgtcctcacagtctatctcggacacctttgttaaagaggtcttaaagtgg
aagtatgaaatgtttgtgaactttgatcagtgtgggccccccaccagcctttgtcagtcc
atctcaagaccggtgcctgtcagatttcaagattgtggagattatttcaatgtttttttc
cctttgatgatactgaatacttttgaaacggtggcacaggagtggatcagctctccaaac
aaagagaagttctatcagttgcatgtacggaaatttcctgctgattataaaaagtactgg
gagtttgtggttcttcttgaggaatgtgaactaactaaacagctgcatccaaaggaaaat
gatttggtgtttttggttcttgaaaaacaaaatggagagaagaagaacacagagagaaat
cgcatgccggatctccacgaatatcactgcggttatgttcataaatttcgccgcacttca
gtcatgcgtaatgggaaatctgagtgttccctttccatccagactcaagataatttgcca
ctcagtttaaatgaactcgtgaaatgcactgtaatcagttctctggtaactacacaaagg
aagttgaaagccatgtctttgttgagtggacggaaccaactagccagagctgttctgaac
ccaaaccccatggacttctgtacgaaagatttactgactacgacgtctgagagaatcatc
gcctacttgaaagatttcaacgaagaccaaaagaaagcgatagaaactgcatacgccatg
gtcaaacactccccatcagttgccaagatctgtttgattcatggaccacctggaacagga
aaatcaaaaactatcgttggcctcctgtaccgcctgctgacagagaaccagaggaagggg
cgttcagatgaaaactccaatgccaaaatcaaacaaaaccgtgtccttgtgtgtgcgcct
tccaacgcggctgttgatgaacttatgaaaaaaatcatcctcgaatttaaagagaagtgt
aaagacaagaagaatcctttgggaaactgtggagatataaatttagtacgtctgggtcca
gaaaagtctattaataatgaggtcctaagatttagtttggacagccaagttaaccacaga
atgaaaaaagacttaccttctcatgttcaggagatgcatagaagaaaggaatttctggat
catcagctagatgaactttcccgccagcgtgctttatgccgaggtggaaaggaaacacag
aggcaagaattagatgaaaaaattgcaaaagtttcaaaagagaggcaggaactagcttct
aaaattaaagaggttcaaggacgcccacaaaaaacacagagcatcatcatcttagagtcc
cacgtcatctgctgcacactgagcacgagtggcggtttactgctcgagtctgcttttcgt
gggcaagggggtgtccccttcagttgtgtcatcgtcgatgaggctgggcagtcttgtgaa
gtggagactcttaccccgctcatccatcgttgtaacaagctgatcctcgtcggagaccca
aaacagctccctcccacggtcatttccatgaaagcacaggagtatggctatgaccagtca
atgatggctcgcttctgcaagctgctggaagacagcgtagagcacaatgtgatcggcagg
ctgcctgttttacagcttactgttcagtacaggatgcacccagacatatgtctcttcccc
tctaattacgtttataacagaagcttgaaaacaaatagactgactgaaaccaatcggtgt
tcatcagactggccatttcaaccttacctcgtgtttgatgtcggagacggttcagaaaga
cgggataatgactcatatataaatgttcaagaaataaaactggtaatggaaataattaaa
cttattaaagacaaaagaagggatgttactttccggaacattggcataataacccattac
aaggctcagaagacgatgattcagaaggatttggacaaagagtttgatagaaaagggcca
gcagaagtagataccgtggacgcgttccagggccgccagaaagattgtgttatcgtcacg
tgtgtcagagcaaatgccctgcaaggctccattggatttctggcaagtttgcaaagattg
aatgtcaccattacacgagccaagtacagcctcttcatcctcggacatttaaggaccttg
atggaaaatcagcactggaatcacctgattcaggacgcacagaagcggggtgccatcgtc
aagacgtgcgacaaaaactacaggcacgacgcagccaagattctgaaactcaagcccgtc
ctgcagagaagtctgactcacccgcccaccgtggccccggaggtggccagaccccagggt
ggcttgcccggcagcaagccagacggtgaatttgccaagacgtctttcccttcctccctg
tatcacgtgccttctggctgtaaggaatccactggtgctgttaccaccaaggaccctgaa
agacctcctattcaggaccggcttcgggacccacgactgcttaggaggctgggcatagac
cccgaagccaaagggacgtgcccgagggatccgcagcccctgagcccccagcatcctggg
gccacgcctccctcgggggagccaggcttccctctgagtcaccaggacctgggtggtgcc
cagctgtccaccgccagagggaccacgctgagcacccagaaccctcccgtgcagtgggag
cctccagctgccggtacagatgtctccgcgagtaaaagagcatgtgactgggaaggaggg
ctcagccgcaggagagagaccagggctttcagcgaaggggaccgggagacgcagagccct
gagagccgtcacccgaagaggcgctccggctgggacaacaggagactggaagaggaagac
agtggttccaagagaagaaagtttttatag
DBGET
integrated database retrieval system
