KEGG   Prionailurus bengalensis (leopard cat): 122478691
Entry
122478691         CDS       T07574                                 
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
pbg  Prionailurus bengalensis (leopard cat)
Pathway
pbg01522  Endocrine resistance
pbg04010  MAPK signaling pathway
pbg04012  ErbB signaling pathway
pbg04014  Ras signaling pathway
pbg04024  cAMP signaling pathway
pbg04068  FoxO signaling pathway
pbg04071  Sphingolipid signaling pathway
pbg04137  Mitophagy - animal
pbg04140  Autophagy - animal
pbg04141  Protein processing in endoplasmic reticulum
pbg04210  Apoptosis
pbg04215  Apoptosis - multiple species
pbg04217  Necroptosis
pbg04310  Wnt signaling pathway
pbg04380  Osteoclast differentiation
pbg04510  Focal adhesion
pbg04530  Tight junction
pbg04620  Toll-like receptor signaling pathway
pbg04621  NOD-like receptor signaling pathway
pbg04622  RIG-I-like receptor signaling pathway
pbg04625  C-type lectin receptor signaling pathway
pbg04657  IL-17 signaling pathway
pbg04658  Th1 and Th2 cell differentiation
pbg04659  Th17 cell differentiation
pbg04660  T cell receptor signaling pathway
pbg04664  Fc epsilon RI signaling pathway
pbg04668  TNF signaling pathway
pbg04722  Neurotrophin signaling pathway
pbg04723  Retrograde endocannabinoid signaling
pbg04728  Dopaminergic synapse
pbg04750  Inflammatory mediator regulation of TRP channels
pbg04910  Insulin signaling pathway
pbg04912  GnRH signaling pathway
pbg04914  Progesterone-mediated oocyte maturation
pbg04917  Prolactin signaling pathway
pbg04920  Adipocytokine signaling pathway
pbg04926  Relaxin signaling pathway
pbg04930  Type II diabetes mellitus
pbg04931  Insulin resistance
pbg04932  Non-alcoholic fatty liver disease
pbg04933  AGE-RAGE signaling pathway in diabetic complications
pbg04935  Growth hormone synthesis, secretion and action
pbg04936  Alcoholic liver disease
pbg05010  Alzheimer disease
pbg05012  Parkinson disease
pbg05016  Huntington disease
pbg05017  Spinocerebellar ataxia
pbg05020  Prion disease
pbg05022  Pathways of neurodegeneration - multiple diseases
pbg05132  Salmonella infection
pbg05133  Pertussis
pbg05135  Yersinia infection
pbg05142  Chagas disease
pbg05145  Toxoplasmosis
pbg05152  Tuberculosis
pbg05161  Hepatitis B
pbg05162  Measles
pbg05166  Human T-cell leukemia virus 1 infection
pbg05167  Kaposi sarcoma-associated herpesvirus infection
pbg05169  Epstein-Barr virus infection
pbg05170  Human immunodeficiency virus 1 infection
pbg05171  Coronavirus disease - COVID-19
pbg05200  Pathways in cancer
pbg05208  Chemical carcinogenesis - reactive oxygen species
pbg05210  Colorectal cancer
pbg05212  Pancreatic cancer
pbg05231  Choline metabolism in cancer
pbg05415  Diabetic cardiomyopathy
pbg05417  Lipid and atherosclerosis
pbg05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pbg00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    122478691 (MAPK10)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    122478691 (MAPK10)
   04012 ErbB signaling pathway
    122478691 (MAPK10)
   04014 Ras signaling pathway
    122478691 (MAPK10)
   04310 Wnt signaling pathway
    122478691 (MAPK10)
   04668 TNF signaling pathway
    122478691 (MAPK10)
   04068 FoxO signaling pathway
    122478691 (MAPK10)
   04071 Sphingolipid signaling pathway
    122478691 (MAPK10)
   04024 cAMP signaling pathway
    122478691 (MAPK10)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    122478691 (MAPK10)
   04137 Mitophagy - animal
    122478691 (MAPK10)
  09143 Cell growth and death
   04210 Apoptosis
    122478691 (MAPK10)
   04215 Apoptosis - multiple species
    122478691 (MAPK10)
   04217 Necroptosis
    122478691 (MAPK10)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    122478691 (MAPK10)
   04530 Tight junction
    122478691 (MAPK10)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    122478691 (MAPK10)
   04621 NOD-like receptor signaling pathway
    122478691 (MAPK10)
   04622 RIG-I-like receptor signaling pathway
    122478691 (MAPK10)
   04625 C-type lectin receptor signaling pathway
    122478691 (MAPK10)
   04660 T cell receptor signaling pathway
    122478691 (MAPK10)
   04658 Th1 and Th2 cell differentiation
    122478691 (MAPK10)
   04659 Th17 cell differentiation
    122478691 (MAPK10)
   04657 IL-17 signaling pathway
    122478691 (MAPK10)
   04664 Fc epsilon RI signaling pathway
    122478691 (MAPK10)
  09152 Endocrine system
   04910 Insulin signaling pathway
    122478691 (MAPK10)
   04920 Adipocytokine signaling pathway
    122478691 (MAPK10)
   04912 GnRH signaling pathway
    122478691 (MAPK10)
   04914 Progesterone-mediated oocyte maturation
    122478691 (MAPK10)
   04917 Prolactin signaling pathway
    122478691 (MAPK10)
   04926 Relaxin signaling pathway
    122478691 (MAPK10)
   04935 Growth hormone synthesis, secretion and action
    122478691 (MAPK10)
  09156 Nervous system
   04728 Dopaminergic synapse
    122478691 (MAPK10)
   04723 Retrograde endocannabinoid signaling
    122478691 (MAPK10)
   04722 Neurotrophin signaling pathway
    122478691 (MAPK10)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    122478691 (MAPK10)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    122478691 (MAPK10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122478691 (MAPK10)
   05208 Chemical carcinogenesis - reactive oxygen species
    122478691 (MAPK10)
   05231 Choline metabolism in cancer
    122478691 (MAPK10)
  09162 Cancer: specific types
   05210 Colorectal cancer
    122478691 (MAPK10)
   05212 Pancreatic cancer
    122478691 (MAPK10)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    122478691 (MAPK10)
   05170 Human immunodeficiency virus 1 infection
    122478691 (MAPK10)
   05161 Hepatitis B
    122478691 (MAPK10)
   05171 Coronavirus disease - COVID-19
    122478691 (MAPK10)
   05162 Measles
    122478691 (MAPK10)
   05167 Kaposi sarcoma-associated herpesvirus infection
    122478691 (MAPK10)
   05169 Epstein-Barr virus infection
    122478691 (MAPK10)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    122478691 (MAPK10)
   05135 Yersinia infection
    122478691 (MAPK10)
   05133 Pertussis
    122478691 (MAPK10)
   05152 Tuberculosis
    122478691 (MAPK10)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    122478691 (MAPK10)
   05142 Chagas disease
    122478691 (MAPK10)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    122478691 (MAPK10)
   05012 Parkinson disease
    122478691 (MAPK10)
   05016 Huntington disease
    122478691 (MAPK10)
   05017 Spinocerebellar ataxia
    122478691 (MAPK10)
   05020 Prion disease
    122478691 (MAPK10)
   05022 Pathways of neurodegeneration - multiple diseases
    122478691 (MAPK10)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    122478691 (MAPK10)
   05418 Fluid shear stress and atherosclerosis
    122478691 (MAPK10)
   05415 Diabetic cardiomyopathy
    122478691 (MAPK10)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    122478691 (MAPK10)
   04936 Alcoholic liver disease
    122478691 (MAPK10)
   04932 Non-alcoholic fatty liver disease
    122478691 (MAPK10)
   04931 Insulin resistance
    122478691 (MAPK10)
   04933 AGE-RAGE signaling pathway in diabetic complications
    122478691 (MAPK10)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    122478691 (MAPK10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pbg01001]
    122478691 (MAPK10)
Enzymes [BR:pbg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     122478691 (MAPK10)
Protein kinases [BR:pbg01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   122478691 (MAPK10)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 122478691
NCBI-ProteinID: XP_043428187
LinkDB
Position
B1:135030971..135347019
AA seq 464 aa
MSLHLLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgagcctccatttattgtactactgcagtgaaccaaccttggatgtgaaaattgccttt
tgtcagggtttcgataaacaagtggatgtgtcatatattgccaaacattacaacatgagc
aaaagcaaagttgacaaccaattctacagtgtggaagtgggagactcaaccttcacagtt
ctcaagcgctaccagaatttaaagcctattggctctggggctcagggaatagtttgtgct
gcgtatgatgccgttcttgacagaaatgtggccattaagaagctcagcagaccctttcag
aaccaaacgcatgccaagagagcttaccgggagctagtcctcatgaagtgtgtgaaccat
aaaaacattattagtttattaaatgtcttcacaccccagaaaacactggaggagttccag
gatgtttacttagtaatggaactgatggatgccaacttgtgtcaggtgattcagatggaa
ttagaccatgagcgaatgtcttacctgctataccaaatgttgtgtggcatcaagcacctc
cactctgctggaattattcacagggatttaaaaccaagtaacattgtagtcaaatctgat
tgtacattgaaaatcctcgactttggactcgccagaacggcaggcacaagtttcatgatg
actccttatgtggttacccgttattatagagcccctgaggttattctgggaatgggctac
aaggagaacgtggatatatggtctgtgggatgcattatgggagaaatggttcgccacaaa
atcctctttccaggaagggactatattgaccagtggaacaaggtgattgagcaactagga
acgccatgcccagaattcatgaagaaattgcaacccacagtaagaaactatgtggagaat
cggcccaagtatgcaggactcaccttccccaagctctttccagattccctcttcccagcg
gactccgagcacaataaactcaaagccagccaagccagggacttattgtcaaagatgcta
gtgattgatccagcaaaaaggatatccgtggatgacgccttacaacacccttatatcaat
gtctggtacgaccctgccgaagtggaggcgcctccacctcagatatatgacaaacagttg
gacgaaagagaacacaccattgaagaatggaaagaacttatctacaaggaggtaatgaat
tcggaagaaaagactaaaaatggtgttgtaaaaggacaaccttctccttcaggtgcagca
gtgaacagcagtgagagtctccctccatcttcgtctgtcaatgacatctcctccatgtcc
accgaccagaccctggcatctgacactgacagcagcctggaagcctcagcaggacccctg
ggttgttgcaggtga

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