Prionailurus bengalensis (leopard cat): 122485035
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Entry
122485035 CDS
T07574
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg00260
Glycine, serine and threonine metabolism
pbg00630
Glyoxylate and dicarboxylate metabolism
pbg00670
One carbon pool by folate
pbg01100
Metabolic pathways
pbg01200
Carbon metabolism
pbg01230
Biosynthesis of amino acids
pbg01240
Biosynthesis of cofactors
pbg01523
Antifolate resistance
pbg04981
Folate transport and metabolism
Module
pbg_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
122485035 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
122485035 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
122485035 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
122485035 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
122485035 (SHMT1)
Enzymes [BR:
pbg01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
122485035 (SHMT1)
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GFIT
Motif
Pfam:
SHMT
Aminotran_1_2
DegT_DnrJ_EryC1
Motif
Other DBs
NCBI-GeneID:
122485035
NCBI-ProteinID:
XP_043439226
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Position
E1:11020188..11047386
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AA seq
484 aa
AA seq
DB search
MTTQVNGAHKDADLWSSHEKMLAQPLKDCDTEVYDIIKKESNRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELEILCQKRALQVYDLDPQCWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
INYDQLEENARLFHPKLIIAGTSCYSRNLDYARLRRIADDNGAYLMADMAHISGLVAAGV
VPSPFEHCHVVSTTTHKTLRGCRAGMIFYRRGVRSVDPKTGKEMLYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTPEFRVYQRQVVANCRVLAETLMELGYKVVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGFLEKEFQK
VAQFIHRGIELTLQIQDDVGARATLKEFKEKLAGDEKHQRAIRALREEVESFAALFPLPG
LPAF
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atgacaactcaagtcaacggggctcacaaggatgctgacctgtggtcctcgcatgagaag
atgctggcacagcccctcaaagactgcgacaccgaggtttacgacatcatcaagaaggag
agtaaccggcagagggttgggctggagctgatcgcctcagagaatttcgccagccgagca
gttctggaggctctgggctcttgcttaaataacaagtactctgaagggtacccagggcag
aggtattatggcgggaccgagttcatcgatgagctggagatcctctgtcagaagcgggcg
ctacaggtctatgatctggacccccaatgctggggggtcaatgtccagccctactcaggc
tccccggcaaacttcgctgtgtacaccgcgctggtggaaccccacgggcgcatcatgggc
ctggacctgcccgacgggggccacctgacccacgggttcatgacagacaagaagaaaatc
tctgctacgtccatcttttttgaatctatgccctataaggtgaacccagacactggctac
atcaactatgaccaactggaggaaaatgcccgcctcttccacccgaagctgattattgca
gggaccagctgctactcccgaaacctggattacgctcgactgaggaggatcgcagacgac
aacggggcctatctcatggccgacatggcgcacatcagcgggctggtggctgccggtgtg
gtgccttccccctttgagcactgccacgtggtgtccaccaccacccacaaaaccctgcga
ggctgccgcgccggcatgatcttctacaggagaggagtgcgcagcgtggatcccaagacc
ggcaaagagatgctgtacaacctggagtcgctcatcaactctgccgtgttcccgggcctg
cagggaggtccccacaaccacgccattgctggggtcgccgtggccctgaaacaagccatg
actccggaattccgggtgtaccagcgccaggtggtggccaactgcagggttctggctgag
accttgatggagctgggctacaaagtggtaacaggtggttctgacaaccatttgatcctc
gtggatctccgttccaaaggcacggatggtggcagggccgagaaggtactagaagcctgc
tctatagcctgcaacaagaacacctgtccaggtgacaaaagcgcgctgcggcccagcgga
ctgcgtctggggactccggcactgacatcccgcggatttttggaaaaagaattccaaaaa
gtggcccagttcattcacagagggatagaactgactctgcagattcaggacgacgttggt
gccagagccaccctgaaggagttcaaggagaaactggccggggacgagaagcaccaaagg
gccatcagggctctcagggaggaagtggagagcttcgcggctctcttccctctgcctggc
ctgcctgccttttag
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