Prionailurus bengalensis (leopard cat): 122485265
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Entry
122485265 CDS
T07574
Symbol
ACACA
Name
(RefSeq) acetyl-CoA carboxylase 1 isoform X1
KO
K11262
acetyl-CoA carboxylase / biotin carboxylase 1 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg00061
Fatty acid biosynthesis
pbg00620
Pyruvate metabolism
pbg00640
Propanoate metabolism
pbg01100
Metabolic pathways
pbg01212
Fatty acid metabolism
pbg04152
AMPK signaling pathway
pbg04910
Insulin signaling pathway
pbg04922
Glucagon signaling pathway
pbg04936
Alcoholic liver disease
Module
pbg_M00082
Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
122485265 (ACACA)
00640 Propanoate metabolism
122485265 (ACACA)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
122485265 (ACACA)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
122485265 (ACACA)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
122485265 (ACACA)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
122485265 (ACACA)
04922 Glucagon signaling pathway
122485265 (ACACA)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
122485265 (ACACA)
Enzymes [BR:
pbg01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
122485265 (ACACA)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
122485265 (ACACA)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
122485265 (ACACA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
122485265
NCBI-ProteinID:
XP_043439740
LinkDB
All DBs
Position
E1:23710114..23992979
Genome browser
AA seq
2385 aa
AA seq
DB search
MWWSTLMSILRASSFWRWISAQTVRIIRALRAHFEGIMDEPSPLAKPLELNQHSRFIIGS
VSEDNSEDEISNLVKLDLLEEKEGSLSPASVGSDTLSDLGISSLQDGLALHMRSSMSGLH
LVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYE
MFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQ
AVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGS
GLRVDWQESDFSKRILNVPQELYQKGYVKDVDDGLKAAEEVGYPVMIKASEGGGGKGIRK
VNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRR
HQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQ
VEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDAPIDFENSAHVPCPRG
HVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSW
GENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQLNRIDTGWLDRLIAEKVQA
ERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQVLPAHTLLNTVDVELIYEGVKYVL
KVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTC
VFEKENDPSVMRSPSAGKLIQYIVEDGGHVFSGQCYAEIEVMKMVMTLTAAESGCIHYVK
RPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPRIQSTALRGEKLHRVFHYVLDNLVNV
MNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKEMA
QYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHM
KAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTM
LIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESI
FLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYEL
NSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFSSNLNHYGMTHVASVSDVLLD
NSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSPPQSPTFPEAGHTSLYDEDKLQVP
RDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLVEHGIRRLTFLVAQKDFRKQVN
YEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKM
HLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAF
NNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTP
TGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKD
LLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDMLTYTELVLDD
QGQLVHMNRLPGGNEIGMVAWKMTLKSPEYPEGRDIIVIGNDITYLIGSFGPQEDLLFLR
ASELARAEGIPRIFVAANSGARIGLAEEIRHMFHVAWVDPEDPYKGYKYLYLTPQDYKRV
SALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGSGMIAGESSLAYNEIITISLVT
CRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVT
HSIVCDDFEGVFTVLHWLSYMPKNVHSLVPLLNSKDPIDRIIEFVPTKAPYDPRWMLAGR
PHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADP
ANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRGFSGGMKDMYDQVL
KFGAYIVDSLRECSQPVLVYIPPQAELRGGSWVVIDPTINPRHMEMYADRESRGSVLEPE
GTVEIKFRRKDLVKTMRRVDPVYIRLAERLGTPELSAAERKELENKLKEREEFLIPIYHQ
VAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLRRLLLEDLVKKKIHNANPELTD
GQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEEDGVRSVIEENIKYISRDYVL
KQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILSTMDSPST
NT seq
7158 nt
NT seq
+upstream
nt +downstream
nt
atgtggtggtccactctgatgtcaatcttgagggctagttctttttggaggtggatatct
gctcagacagtaagaattataagagctctgagagctcattttgaaggaataatggatgaa
ccatcccccttggccaaacctctggagctgaaccagcactctcggttcataattggttct
gtatctgaagataactcagaggatgaaatcagcaacctggtgaagctggacctactggag
gagaaggaaggctctctgtcaccagcttctgttggctcagatacgctctctgatttgggg
atttccagcctacaggatggcttggccttgcacatgaggtccagcatgtctggcttgcat
ctagtaaagcaaggtcgagaccgaaagaaaatagactcacagcgagatttcactgtagct
tcaccagcagaatttgttacgcgttttggggggaataaagtgattgagaaggttcttatt
gccaacaatggcatcgcagcagtgaaatgcatgcggtccatccgccgatggtcttatgag
atgtttcgaaatgaacgtgcaatccgatttgttgttatggtcacacctgaagacctgaaa
gccaatgcagaatacattaagatggcagatcactatgtgccggtgccaggaggaccaaac
aacaacaactatgcaaacgtggaattaattcttgatattgctaaaaggatcccagtacaa
gcagtgtgggctggctggggtcatgcttctgagaatcccaagctcccagaacttcttttg
aaaaatggcatcgccttcatgggtcctccaagccaggccatgtgggctttgggggataag
attgcatcttccatagtggcccaaactgctggtatcccaactcttccctggagtgggagt
ggtcttcgtgtggactggcaggaaagtgatttttcaaaacgtatcttaaatgttccccag
gaattatatcaaaaaggttatgtgaaggatgtggatgatgggctgaaggcagcagaggaa
gttggatatccagtaatgatcaaggcctcagaaggaggaggagggaaaggaatcagaaaa
gttaacaatgcagatgacttccctaacctcttcagacaggttcaagctgaagtccctgga
tctcctatatttgtgatgagactagccaaacaatcccgtcatctggaggtacagatttta
gcagatcagtacggcaatgctatctctctgtttggtcgtgactgctctgtgcagcgcagg
catcagaagattattgaagaagcaccagctgctattgctactccagcagtattcgaacat
atggaacagtgtgcggtgaaacttgccaaaatggttggttatgtgagtgcagggactgtc
gaatacctctacagccaggatggaagcttctactttctggaactgaaccctcggctacag
gtggagcacccttgtacagagatggtggctgatgtcaacctccctgcagcgcaactccag
attgccatggggatccctctgtatagaatcaaggatattcgtatgatgtatggagtatct
ccctggggtgatgctcccattgattttgaaaattctgctcatgttccttgcccaaggggc
catgttattgctgctcggatcactagtgaaaatccagatgagggttttaagcccagctca
ggaacagttcaggaactgaatttccgtagcaataagaatgtttggggttatttcagtgtt
gctgctgcagggggccttcacgaatttgctgattctcagtttggtcactgcttctcctgg
ggagaaaacagagaggaagcaatttcaaacatggtggtggctttgaaggagctatctatt
cggggtgactttcgaactacagttgaatacctcatcaaattgctggagactgagagtttt
cagctgaatagaattgacactggctggctagacagactgatagcagaaaaagtacaggca
gagcgacctgataccatgttgggagttgtgtgtggggctctccacgtggcagatgtgagc
ctacggaatagcatctctaacttccttcattccttagaaaggggtcaagttcttcctgct
catacgcttctgaatacggtagatgttgaacttatctatgagggagtcaaatatgtactt
aaggtgactcgacagtcccccaactcgtatgtggtgatcatgaacgggtcatgcgtagaa
gtagatgtgcatcggctgagtgatggagggctgctcctgtcctatgatggcagcagttat
accacatacatgaaggaggaagtggatagatatcgtatcacaattggcaataagacctgt
gtgtttgagaaggaaaatgacccttcagtgatgcgctcaccttctgctgggaagttaatc
cagtatattgtggaggatggaggccatgtgttttctggccagtgctatgctgagattgag
gtgatgaagatggtaatgaccttaacagcagcagagtctggctgtatccattatgtcaaa
cggcctggagcagctcttgaccctggctgtgtgatagccaaaatgcagttagacaacccc
agcaaggtccaacaggctgagcttcacacgggtagtctgccacggatccagagcacagca
ctgagaggcgagaagctccatcgagtgttccattatgtcctggataatctggtcaacgta
atgaatggatactgccttccagatcctttttttagtagcagggtaaaagactgggtagag
cggttgatgaaaaccctcagagatccctccttgcctctcctagaattgcaagatatcatg
accagtgtctctggccgtattcccccgaatgtggagaagtctatcaagaaggaaatggct
cagtatgccagcaacatcacatcagtcctctgtcagtttcccagccagcagattgccaac
atcctagatagccatgcagctacattgaaccggaaatctgaacgggaagttttcttcatg
aacactcagagcattgtccagctggtacagaggtaccgaagtggcatccgaggccacatg
aaggctgttgtgatggatctgctacggcagtacctgcgagtagagacacagttccagaat
ggtcactatgacaaatgtgtgtttgcccttcgagaagagaacaagagtgacatgaacact
gtgctaaactatatcttctctcatgctcaagtcaccaagaagaatcttctggtcacaatg
cttattgatcagttgtgtggtcgggaccctactctcactgatgagctgctgaatattctc
acagagctaactcaactcagtaagaccaccaatgccaaagtggcacttcgagcacgccag
gttcttattgcctcccatttgccatcatatgagcttcgccataaccaagtagagtctatc
ttcctttcagctattgacatgtatggacatcagttttgcattgagaacctgcagaaactc
atcttgtctgaaacatctatttttgatgtcctaccaaacttcttctatcacagcaaccag
gtagtgaggatggcagctctggaggtttatgttcgaagggcttacattgcctatgaactt
aacagcgtccaacatcgccagcttaaggacaatacctgcgtggtggaattccagttcatg
ctgcccacatcgcatccaaacagagggaacatccccacgctaaacagaatgtccttctcc
tccaacctcaaccactatggcatgactcacgtagctagtgtcagcgatgtgctgttggac
aactcattcactccaccgtgtcagcggatgggcggaatggtctcttttcggactttcgaa
gattttgtcaggatctttgatgaagtgatgggctgcttctgtgactccccaccccaaagc
cccacgttccctgaggcaggtcacacatctctgtatgatgaagacaagttacaggtcccc
agggatgaaccaattcacattctgaatgtggctatcaagactgactgtgatattgaggat
gacagactggcagctatgttcagagagtttacccaacaaaataaagctaccctggttgag
catgggatacggcgccttactttcctggtcgcacaaaaggatttcagaaaacaggtcaac
tatgaggtggatcagagatttcatagagaatttcctaaatttttcacgttccgagcaagg
gataagtttgaggaggatcgtatctatcgtcacctggagcctgccctagctttccagtta
gaactgaaccggatgagaaattttgaccttactgccattccatgtgctaatcataagatg
cacctgtatcttggggcagccaaggtggaagtgggcactgaagtgacagactataggttc
tttgttcgtgcaatcatcagacattctgatctggtcaccaaggaagcttcttttgaatat
ctacaaaatgaaggggagcggctgctcctggaggccatggatgaattggaagttgctttt
aataatacaaatgttcgcactgactgcaaccacatcttcctcaactttgtgcccacagtc
attatggacccatcaaagattgaggaatctgtgcggagcatggtaatgcgctatggaagt
cggctgtggaaattacgtgtcctccaggcagaactgaaaatcaacattcgcctgacacca
actggaaaagcaattcccatccgcctcttcctgacaaatgagtccggctattacttggac
atcagcttgtacaaggaagtgactgactccaggacagcacagatcatgtttcaggcatat
ggagacaaacagggaccattgcatggaatgttaatcaacactccatatgtcaccaaagac
ctacttcaatcaaagagattccaggcacaatccttggggacaacatacatatatgatatc
ccagagatgtttcggcagtctctgatcaaactctgggagtctatgtccactcaagcattc
cttccatcaccccccctgccttctgacatgctgacgtatactgagcttgtgttggatgat
cagggtcagctggtccacatgaacaggcttccaggaggaaatgagattggcatggtagct
tggaaaatgacccttaaaagtcctgaatatccagaaggccgagatatcattgttattggc
aatgacatcacatacctaattgggtcctttgggccccaggaggatttgctgtttctcaga
gcttctgagcttgccagggcagagggtatcccacgcatctttgtcgcagccaacagcgga
gcacgaattggactggcagaggaaattcgtcatatgtttcacgtggcctgggtagatcct
gaggatccttacaagggatacaaatacttatatctgacccctcaggattataagagggtc
agtgctctcaactctgtccactgtgaacatgtagaagatgaaggagaatccaggtacaag
ataactgatattattgggaaggaagagggacttggagcagagaaccttcgaggctctgga
atgattgctggagaatcctcattggcctataatgagattatcaccatcagcttggttaca
tgccgggctattgggattggagcttaccttgtccggctgggacagagaaccatccaggtt
gaaaattctcacttaattctgaccggagctggagctctcaacaaagtccttgggcgggaa
gtatacacctccaataaccagcttgggggcatccagatcatgcacaacaatggggtgacc
cacagcatcgtttgtgatgactttgaaggggttttcactgtcctacactggctgtcttac
atgcctaagaatgtgcacagtttagtacctctcctgaactccaaggatcctatagataga
atcatcgaatttgttcctacgaaggccccctatgatcctcgatggatgctagcaggccgt
cctcacccaacccagaaaggtcagtggttgagtggattctttgactatggatctttctct
gaaatcatgcaaccctgggcacagactgtggtggttggcagagccaggctaggaggaata
cctgtaggagtagttgctgtagaaacccgaacagtggaactaagtatcccagccgaccct
gcaaacctggattctgaagccaagataatccagcaggctggccaggtttggtttccagat
tctgcgtttaagacctatcaggctatcaaggacttcaaccgagaagggctgcctctgatg
gtctttgccaactggagaggcttctccggtgggatgaaagatatgtacgaccaggtgctg
aagtttggtgcttacatcgtggatagcttacgggagtgctcccagcctgtgctggtttac
attcctcctcaagctgagctccggggtggctcctgggttgtgattgaccccaccatcaac
ccccggcacatggagatgtacgctgaccgagaaagcaggggatcagttctggagccagaa
gggacagtagaaatcaaattccgcagaaaagatctggtgaaaaccatgcgtcgggtggac
ccagtctacattcgcttggctgaacgattgggcaccccagagctaagcgcagctgagcgg
aaggagctggagaacaagttgaaggagcgggaggaattcctaattcccatttaccatcag
gtagccgtgcagtttgctgacttgcacgacacaccaggccggatgcaggagaagggtgtt
attaacgacatcctggattggaaaacatcccgtaccttcttctactggcggctgaggcgt
ctcctgctggaggacctggtcaaaaagaaaatccacaatgccaacccagagctcactgat
ggtcagatccaggccatgttaaggcgctggtttgtagaagtggaaggaaccgtgaaggcc
tatgtttgggacaataacaaggatctagtggagtggctggagaaacagctgaccgaggaa
gatggtgttcgctcagtaatcgaggaaaacatcaaatacatcagcagagactatgtcctc
aagcagatccgcagcttggtacaggccaatcccgaggttgccatggattccatcgtccat
atgacccagcacatctcacccactcagcgagcagaagtcgtacggatcctctccacaatg
gactccccttcaacatag
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integrated database retrieval system
