KEGG   Prionailurus bengalensis (leopard cat): 122485296
Entry
122485296         CDS       T07574                                 
Symbol
RPS6KB1
Name
(RefSeq) ribosomal protein S6 kinase beta-1 isoform X1
  KO
K04688  ribosomal protein S6 kinase beta [EC:2.7.11.1]
Organism
pbg  Prionailurus bengalensis (leopard cat)
Pathway
pbg01521  EGFR tyrosine kinase inhibitor resistance
pbg01522  Endocrine resistance
pbg04012  ErbB signaling pathway
pbg04066  HIF-1 signaling pathway
pbg04140  Autophagy - animal
pbg04150  mTOR signaling pathway
pbg04151  PI3K-Akt signaling pathway
pbg04152  AMPK signaling pathway
pbg04211  Longevity regulating pathway
pbg04213  Longevity regulating pathway - multiple species
pbg04350  TGF-beta signaling pathway
pbg04371  Apelin signaling pathway
pbg04666  Fc gamma R-mediated phagocytosis
pbg04714  Thermogenesis
pbg04910  Insulin signaling pathway
pbg04931  Insulin resistance
pbg05163  Human cytomegalovirus infection
pbg05165  Human papillomavirus infection
pbg05170  Human immunodeficiency virus 1 infection
pbg05200  Pathways in cancer
pbg05205  Proteoglycans in cancer
pbg05207  Chemical carcinogenesis - receptor activation
pbg05210  Colorectal cancer
pbg05212  Pancreatic cancer
pbg05221  Acute myeloid leukemia
pbg05224  Breast cancer
pbg05225  Hepatocellular carcinoma
pbg05226  Gastric cancer
pbg05231  Choline metabolism in cancer
pbg05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:pbg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    122485296 (RPS6KB1)
   04350 TGF-beta signaling pathway
    122485296 (RPS6KB1)
   04371 Apelin signaling pathway
    122485296 (RPS6KB1)
   04066 HIF-1 signaling pathway
    122485296 (RPS6KB1)
   04151 PI3K-Akt signaling pathway
    122485296 (RPS6KB1)
   04152 AMPK signaling pathway
    122485296 (RPS6KB1)
   04150 mTOR signaling pathway
    122485296 (RPS6KB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    122485296 (RPS6KB1)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    122485296 (RPS6KB1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    122485296 (RPS6KB1)
  09149 Aging
   04211 Longevity regulating pathway
    122485296 (RPS6KB1)
   04213 Longevity regulating pathway - multiple species
    122485296 (RPS6KB1)
  09159 Environmental adaptation
   04714 Thermogenesis
    122485296 (RPS6KB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122485296 (RPS6KB1)
   05205 Proteoglycans in cancer
    122485296 (RPS6KB1)
   05207 Chemical carcinogenesis - receptor activation
    122485296 (RPS6KB1)
   05231 Choline metabolism in cancer
    122485296 (RPS6KB1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    122485296 (RPS6KB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    122485296 (RPS6KB1)
   05212 Pancreatic cancer
    122485296 (RPS6KB1)
   05225 Hepatocellular carcinoma
    122485296 (RPS6KB1)
   05226 Gastric cancer
    122485296 (RPS6KB1)
   05221 Acute myeloid leukemia
    122485296 (RPS6KB1)
   05224 Breast cancer
    122485296 (RPS6KB1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    122485296 (RPS6KB1)
   05163 Human cytomegalovirus infection
    122485296 (RPS6KB1)
   05165 Human papillomavirus infection
    122485296 (RPS6KB1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    122485296 (RPS6KB1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    122485296 (RPS6KB1)
   01522 Endocrine resistance
    122485296 (RPS6KB1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pbg01001]
    122485296 (RPS6KB1)
Enzymes [BR:pbg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     122485296 (RPS6KB1)
Protein kinases [BR:pbg01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   122485296 (RPS6KB1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 DUF1015
Other DBs
NCBI-GeneID: 122485296
NCBI-ProteinID: XP_043439807
LinkDB
Position
E1:complement(26710183..26782720)
AA seq 525 aa
MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG
PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF
AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL
FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC
KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK
TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL
LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE
SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG
VEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL
NT seq 1578 nt   +upstreamnt  +downstreamnt
atgaggcgacgacggaggcgggacggcttttacccagcgccggacttccgagacagggaa
gctgaggacatggcaggagtgtttgacatagacctggaccagccagaggacgcgggctct
gaggatgagctggaggaggggggtcagttaaatgaaagcatggaccatgggggagttgga
ccatatgaacttggcatggaacattgtgagaaatttgaaatttcggaaactagtgtgaac
agagggccagaaaaaatcagaccagaatgtttcgagctacttcgggtacttggtaaaggg
ggctatggaaaggtttttcaagtacggaaagtaacaggagcaaatactgggaaaatattt
gccatgaaggtgcttaaaaaggcaatgatagtaagaaatgctaaagatacagctcataca
aaagcagaacggaatattctggaggaagtaaagcatcccttcattgtggatttaatttat
gcctttcagaccggtggaaaactctacctcatccttgagtatctcagcggaggagaatta
tttatgcagttagaaagagaaggaatatttatggaagacacagcctgcttttacttggca
gaaatctccatggctttggggcatttacatcaaaaggggatcatctacagagacctgaag
ccggagaatatcatgctaaatcaccaaggtcatgtgaaactaacagactttggactatgc
aaggaatctattcatgatggaacagtcacacacacattttgtggaacaatagaatacatg
gcccctgaaatcttgatgagaagtggccacaatcgtgctgtggattggtggagtttggga
gcattaatgtatgacatgctgactggagcacccccgttcactggggagaatagaaagaaa
acaattgacaaaatcctcaaatgtaaactcaatttgcctccctacctcacacaagaagcc
agagatctgcttaaaaagctgctgaaaagaaatgctgcttctcgtcttggagctggtcct
ggggatgctggagaagttcaagctcatccattcttcaggcatattaattgggaagaactg
ctggctaggaaggtggaacccccttttaaacctctgttgcaatctgaggaggatgtgagt
cagtttgattcaaagtttacacgtcagacacctgttgacagcccagatgactcaactctc
agtgaaagtgccaaccaggtctttctgggttttacatatgttgctccatctgtacttgaa
agtgtgaaagaaaaattttcctttgaaccaaaaatccgatcacctcgaagatttattggc
agcccgcgaacacctgtcagcccagtcaaattttctcctggggatttctggggaagaggt
gcttcagccagcacagcaaatcctcagacacctgtggaatatccaatggaaacaagtgga
gtagagcagatggatgtgacgatgagtggggaagcttcagcaccacttcccatacgacag
ccgaactctgggccatacaaaaaacaagctttccccatgatctccaaacgaccagagcac
ctacgtatgaatctatga

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