Prionailurus bengalensis (leopard cat): 122485778
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Entry
122485778 CDS
T07574
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg04140
Autophagy - animal
pbg04141
Protein processing in endoplasmic reticulum
pbg04210
Apoptosis
pbg04932
Non-alcoholic fatty liver disease
pbg05010
Alzheimer disease
pbg05012
Parkinson disease
pbg05014
Amyotrophic lateral sclerosis
pbg05016
Huntington disease
pbg05017
Spinocerebellar ataxia
pbg05022
Pathways of neurodegeneration - multiple diseases
pbg05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
122485778 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
122485778 (ERN1)
09143 Cell growth and death
04210 Apoptosis
122485778 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
122485778 (ERN1)
05012 Parkinson disease
122485778 (ERN1)
05014 Amyotrophic lateral sclerosis
122485778 (ERN1)
05016 Huntington disease
122485778 (ERN1)
05017 Spinocerebellar ataxia
122485778 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
122485778 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
122485778 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
122485778 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pbg01001
]
122485778 (ERN1)
Enzymes [BR:
pbg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
122485778 (ERN1)
Protein kinases [BR:
pbg01001
]
Serine/threonine kinases: Other
IRE family
122485778 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
Beta-prop_ACSF4
PQQ_2
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
122485778
NCBI-ProteinID:
XP_043440929
LinkDB
All DBs
Position
E1:complement(46050675..46130967)
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AA seq
972 aa
AA seq
DB search
MPVRLLLALLLSGLGIFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQ
VPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQD
IWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYA
ASLPEDDGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMHI
NVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHEG
VAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNYWLLIG
HHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVEQTSENAPTAVSQEVE
EKFEHAPAKPEAPVDSVLKDIATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQKEL
EKIQLLQQQQLPFHPPGDGAQDAELLDSSGLYSESSGTSSPSTSPRASNHSLHSSGSASR
AGASPFLEQDDEDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPEC
FSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLGLEP
ITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHSF
SRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANI
LLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDV
SDRIEKESLDGPIVKQLERGGRAVVKTDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMR
NKKHHYRELPAEVRETLGSLPDDFVRYFTSRFPHLLPHTYRAMEPCSHERLFQPYYFHEP
PELRPPVTPDAL
NT seq
2919 nt
NT seq
+upstream
nt +downstream
nt
atgccggtccggctgctgctggcgctgctgctgtccggcctcgggatttttggaagtccc
agcacagtgacacttcccgaaaccttgttgtttgtgtcaaccctggatggaagcttgcat
gctgtcagtaagaggacgggctcaatcaaatggactttaaaagaagatccggttctgcag
gttccaacgcatgtggaagagcctgccttcctcccagatcccaatgatggcagcctgtat
acacttgggggcaagaataatgaaggcctgacgaaacttccctttaccatcccagagctc
gtacaggcatccccatgccgaagttcagatggaattctctacatgggtaaaaagcaggac
atttggtatgttattgatcttctgaccggggagaagcaacagactttgtcatcggccttt
gcagacagtctctgcccatcaacctctctgctgtatctcgggcgaacagagtacacaatc
accatgtacgacaccaaaacccgcgagctccggtggaatgccacctacttcgactacgcg
gcctcactgccggaggacgacggggactacaagatgtcccactttgtgtccaacggcgat
gggctggtggtgaccgtggacagtgaatctggcgacgtcctgtggatccaaaactacgct
tcccctgtggtggccttttatgtctggcagcgggagggtctgaggaaggtgatgcacatc
aacgtcgcagtggagacgctgcgctatctgaccttcatgtctggggaggtgggccgcatc
accaagtggaagtacccattccccaaggagacggaggccaagagcaagctgacgcccacc
ctgtatgtcgggaaatactccaccagcctgtatgcctccccctccatggtgcacgagggg
gtcgccgttgtgccccggggcagcacacttcctttgctggaaggcccccagactgacggg
gtcaccattggggacaaaggggagtgtgtgatcacgcccagcacagacctaaagtttgac
cctgggctcaaagggaagagcaagctcaactacttgaggaactactggcttctgatagga
caccatgaaacccccctgtctgcgtctaccaagatgctggagagattccccaataatctg
cccaaacatcgagaaaatgtgattcctgccgattcagagaagaagagctttgaggaagtt
atcaacctggtcgagcagacttcagaaaacgcgcccaccgccgtttcacaggaggtggag
gagaagttcgagcatgcccccgctaagcccgaggcccccgtggactctgtgctgaaggac
atagccaccatcatcctgagcaccttcctgctcatcggctgggtggccttcatcatcacc
taccccttgagcatgcatcagcagcagcagctccagcaccagcagttccagaaggaacta
gagaaaatccagctcctgcaacagcagcagctgcccttccatccccctggagacggggct
caggatgctgagctcctggactcgtccggcctgtactcagagagctcgggcaccagcagc
cccagcacatcccccagagcctccaaccactcgctccactccagtggctctgcctccagg
gctggtgccagccccttcctggagcaggacgatgaagatgaggaaaccagcatggtgatt
gttgggaagatctcattctgtcccaaggacgtgctgggccacggagctgagggcacgatt
gtgtaccggggcatgttcgacaaccgcgacgtggccgtcaagaggatcctccccgagtgt
ttcagtttcgcggaccgtgaggtccagctgcttcgggaatcagacgagcaccccaacgtg
attcgttacttctgcacggagagggaccggcagttccagtacattgccatcgagctgtgt
gcggccaccctgcaggagtacgtggagcagaaggacttcgcccacctcggcctggagccc
atcaccttgctgcagcagaccacctcgggcctggcccatttgcactccctcaacattgtt
cacagagacctgaagccccacaacattctcctgtccatgcccaacgcacatggcaggatc
aaggccatgatctctgactttggcctctgcaagaagctggctgtgggcaggcacagtttc
agccgccgctcaggagtgcctggcacagaaggctggatcgctccggagatgctgagcgag
gactgtaaggacaatcccacctacacagtggacatcttctctgcgggctgtgtcttttac
tacgtgatatctgagggcagccacccttttggcaagtccctgcagcggcaggccaacatc
ctcctgggcgcctacagcctcgactgcttacacccggagaagcacgaagacgtcattgcc
cgggaattaatagagaagatgatcgcaatggatcctcagaaacgcccctctgcgaagcat
gtgctgaagcacccgttcttctggagcctggaaaagcagctccagttcttccaggacgtg
agtgaccgaatagaaaaggaatccctggacggcccgatagtgaagcagctggagcgaggt
gggagagccgtggtgaagacagactggagagagaacatcaccgtccccctgcagacagat
ctgcgtaaattcagaacctataaaggtggctctgtccgcgacctgctccgagccatgaga
aacaagaagcaccactaccgggagctccctgcggaggtgcgggagacgctgggctctctc
cccgacgactttgtgcgctacttcacgtcccgcttcccccacctcctcccccacacctac
cgggccatggagccctgcagccacgagaggctcttccagccttactacttccacgagccc
ccagagctccggccccccgtgactccagacgccctttga
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