Prionailurus bengalensis (leopard cat): 122486859
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Entry
122486859 CDS
T07574
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg04217
Necroptosis
pbg04380
Osteoclast differentiation
pbg04620
Toll-like receptor signaling pathway
pbg04621
NOD-like receptor signaling pathway
pbg04630
JAK-STAT signaling pathway
pbg04658
Th1 and Th2 cell differentiation
pbg04659
Th17 cell differentiation
pbg05145
Toxoplasmosis
pbg05160
Hepatitis C
pbg05161
Hepatitis B
pbg05162
Measles
pbg05164
Influenza A
pbg05165
Human papillomavirus infection
pbg05167
Kaposi sarcoma-associated herpesvirus infection
pbg05168
Herpes simplex virus 1 infection
pbg05169
Epstein-Barr virus infection
pbg05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
122486859 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
122486859 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
122486859 (TYK2)
04621 NOD-like receptor signaling pathway
122486859 (TYK2)
04658 Th1 and Th2 cell differentiation
122486859 (TYK2)
04659 Th17 cell differentiation
122486859 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
122486859 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
122486859 (TYK2)
05160 Hepatitis C
122486859 (TYK2)
05171 Coronavirus disease - COVID-19
122486859 (TYK2)
05164 Influenza A
122486859 (TYK2)
05162 Measles
122486859 (TYK2)
05168 Herpes simplex virus 1 infection
122486859 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
122486859 (TYK2)
05169 Epstein-Barr virus infection
122486859 (TYK2)
05165 Human papillomavirus infection
122486859 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
122486859 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pbg01001
]
122486859 (TYK2)
Enzymes [BR:
pbg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
122486859 (TYK2)
Protein kinases [BR:
pbg01001
]
Non-receptor tyrosine kinases
JAK family [OT]
122486859 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
Kinase-like
Kdo
FERM_C_FAK1
ABC1
RIO1
RA_2
Motif
Other DBs
NCBI-GeneID:
122486859
NCBI-ProteinID:
XP_043442432
LinkDB
All DBs
Position
A2:complement(7843360..7862964)
Genome browser
AA seq
1181 aa
AA seq
DB search
MPLCRWGATTRDSRPDGDEAQPMVSRGGLKVLLHWAGPDGGDPWVTFSEATLTAEEVCIH
IAHKVGITPSCLNLFALFDAQAQVWLPPNHILEVSRDMNLTLYFRMRFYFRNWHSMNPQE
PAVYRCGPTRAKSSSEQAEQGVQLLDPASFEYLFEQGKHEFVNDVAPLWELSSEEEIHHF
KNESLGMAFLHLCHLALCHGIPLEKVAKKISFKDCIPRSFRLQLRRHNALTRLRLRRLFR
RFVRAFQPGHVSQPVIMVKYLATLEQLAPRFGTERVLVCRLEERAQAVGDPCYVRDGGRS
PPEPGPELAPGPPTHEVLVTGTGGIRWRPVQAEGPSGDGCSRNARAGPSGKKSKAQEVGN
QPVDRPQEAPWAYFCDFQDITHVVLKERHVSIHCQDKCLELTLPSRAVALSLVSLVDGYF
RLTADSSHYLCREVAPPRLVMSIRDGIHGPLLEPFVLAKLRPEDGLYLIHWSTSHLNRLI
LTVAQRDQAPGRQQLHLRKFPIELRAGSFELEGWDRSFPSVRELRTALQGCSLRAGDDCF
SLRRCCLPRPGELSNLIIMRGSRASPGPLNLSQLSFHRVCQDDITQLSHLGQGTRTNVYE
GILRVGERGPKEGTADGGDPPTPSGDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS
HVHLAFVHGVCVHGSENIMVTEYVEHGPLDVWLRRERGHVPVAWKVAVAQQLASALSYLE
DKSLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWTAPECLSG
GASTLTTAADKWGFGVTLLEICFDGEAPLQGRGPSEKECFYQKQHQLPQPSCPELATLTS
QCLTYEPAQRPSFRTILRDLTQLQPQNLADVLAVNPDSPASDPTVFHKRYLKKIRDLGEG
HFGKVSLYCYDPTNDGTGEMVAVKALKAGGGPQLRTGWRREIDILRTLYHKHIVKYKGCC
EDQGEKSVQLVMEYVPLGSLRDYLPRHNVGLAQLLLFAQQICEGMAYLHAQHYVHRDLAA
RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWS
FGVTMYELLTYCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPRPEKCPCEIYL
LMKNCWEAEASFRPTFQNLIPILKTVQEKYQGQAASVFNVC
NT seq
3546 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccgttggggtgccaccaccagggacagcaggcctgatggggatgaggct
cagcccatggtctccaggggaggcctaaaggtcctcctgcactgggctggccctgatggc
ggggacccctgggtcaccttcagcgaggccacactgaccgcagaggaggtctgcatccac
atcgcacacaaagtcggcatcactccatcctgcctcaatctcttcgccctctttgatgcc
caggcccaggtgtggctgcccccaaaccacatcttggaggtctccagagacatgaacctg
acattgtacttccgcatgaggttttatttccggaactggcacagcatgaatcctcaggag
ccagccgtgtaccgctgtgggcccaccagggccaagtcttcctcagaacaggcagagcag
ggggtgcaactcctggacccagcctcctttgagtacctctttgagcagggcaagcacgag
tttgtgaatgatgtggcaccactgtgggagctgtcgagcgaggaggagatccaccatttt
aagaacgagagcctgggcatggcctttctgcacctctgccacctcgccctttgccatggt
atccccctggagaaggtggccaagaagatcagcttcaaggactgcatcccacgctccttc
cgcctgcagctccggcggcacaacgcgttaacacggctgcgcctacggaggctcttccgc
aggtttgtgcgggccttccagccgggccacgtctcccagccggtcatcatggtcaagtac
ctggccacgctggagcagctggcaccccgcttcggcacggagcgcgtgctcgtgtgccgg
ctggaggagcgggcccaggccgtgggggacccctgctacgtccgggacgggggccggtcc
cccccggagcctgggcctgaattggcccccggaccccctactcatgaggtgctggtgaca
ggcactggtggcatccggtggcggccagtccaggcagagggtcccagtggcgatggttgc
agcaggaacgcccgtgctggcccatcagggaagaaaagcaaggcccaggaggtgggcaac
cagccagtggacaggcctcaggaagcgccatgggcctacttctgtgacttccaggacatc
acccacgtggtgctgaaagagcgccacgtcagcatccactgtcaggacaagtgcctggag
ctcaccctgccttcccgggctgtggccctgtccttggtgtcgctggtggacggctatttc
cgcctgacggccgactcgagccactacctgtgccgggaggtggcccctccgcggctggtg
atgagcatccgggatggcatccacgggcccttgctggagccattcgtgctggccaagctg
cggcccgaagatggcctctacctcatccactggagcaccagccacctcaaccgtctcatc
ctcacggtggcccagcgtgaccaggcacctggcaggcagcagctgcacctccgtaaattc
cccattgagctgcgggccgggagcttcgagctggagggctgggaccgctccttcccgagc
gtgcgggagctgcgcaccgccctgcagggctgctcgctgcgggccggggacgactgtttc
tccctgcgccgctgctgcctgccacggcccggagagctctccaacctcatcatcatgcgt
gggtctcgggccagccctgggccactcaacctcagccagctcagcttccaccgcgtctgc
caggatgacattacccagctgtctcacttgggccaaggcacgaggaccaatgtgtatgag
ggcatcttacgggtgggggaaagaggccccaaggagggcacggcagatggtggggacccc
cccacgcccagtggggaccgtgggcaggagctacgagtggtactcaaggtgctggacccc
agtcaccacgacatcgccctggccttctacgagacagccagcctcatgagccaggtctcc
cacgtgcacctggcctttgtgcacggcgtctgcgtgcacggctctgagaacatcatggtg
acagagtacgtggagcacggacccctggatgtgtggctgcggcgggagaggggccacgtg
cctgtggcctggaaggtggcagtggcccagcagctggccagcgctctcagctacctggaa
gacaagagcctggttcatggtaatgtgtgtggccggaacatcctgctggcacggctggga
ctggcggagggcaccagccccttcatcaagctgagcgatcccggtgtgggcctgggcgcc
ctttccagggaggagcgggtagagaggatcccctggacagcccccgagtgcctgtcaggt
ggggccagcaccctaaccactgcagctgacaaatggggctttggtgtcaccctcctggag
atctgcttcgacggggaggcccctctgcagggccgcggcccttctgagaaagagtgcttc
taccagaagcagcaccagcttcctcagccctcgtgcccggagctggccacactcaccagc
cagtgcctgacctatgaaccagctcagcggccctccttccgcaccatcctgcgtgacctc
actcagctgcagccccagaatcttgctgacgtcttggctgtgaaccccgactcgcctgca
tcagaccccaccgttttccacaagcgctatttgaaaaagatccgggatctgggcgagggt
catttcggcaaggtcagtctgtattgctacgacccgactaacgacggcaccggcgagatg
gtggctgtgaaggccctcaaggcgggcgggggcccccagctccgcactggctggcggcga
gagatcgacatcctgcgcacgctctaccacaagcacatcgtcaaatacaagggatgctgt
gaggaccaaggagagaagtcggtgcagctcgttatggagtacgtgcctctgggcagcctc
cgggactaccttccccggcacaacgtcggactggcccaactgctactcttcgcccagcag
atctgtgagggcatggcctaccttcatgcacagcactacgtccaccgagacctggccgcc
cgcaacgtgctgctggacaacgacaggctggtcaaaatcggggactttggcctagccaag
gctgtgcctgaaggccatgagtactaccgcgtgcgcgaagatggggacagccccgtattc
tggtatgctccagagtgcctgaaggagtgtaagttctactatgcatccgacgtctggtcc
ttcggggtcaccatgtatgagctgctgacctactgtgactccagccagagccccccttcg
aaattcatcgagctcataggcctcacccaagggcagatgacggtgctgaggctcactgag
ctgctggaacgaggggagaggctgccgcggccagagaaatgcccttgcgagatctacctc
ctcatgaagaactgctgggaggcagaggcctcattccgccccactttccagaacctcatc
cccattctcaagacggtccaggagaaataccaaggccaggccgcctcagtgttcaatgtg
tgctga
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integrated database retrieval system
