Prionailurus bengalensis (leopard cat): 122486861
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Entry
122486861 CDS
T07574
Symbol
PDE4A
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg00230
Purine metabolism
pbg01100
Metabolic pathways
pbg04024
cAMP signaling pathway
pbg04928
Parathyroid hormone synthesis, secretion and action
pbg05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
122486861 (PDE4A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
122486861 (PDE4A)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
122486861 (PDE4A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
122486861 (PDE4A)
Enzymes [BR:
pbg01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
122486861 (PDE4A)
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Motif
Pfam:
PDEase_I
PDE4_UCR
Emfourin
Motif
Other DBs
NCBI-GeneID:
122486861
NCBI-ProteinID:
XP_043442435
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Position
A2:7888015..7928237
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AA seq
810 aa
AA seq
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MRSGTAPRARPRPPDLTLPPAGPESLAHFSFSDEDTCWHPPGRPVSFEAENGPTPSPGRS
PLDSQASPGLVLHAGGAISQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPF
AQVLASLRSVRSNFSLLTNVPIPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDWC
LEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIP
SPTMKDREKQPAPRQRPSQQPPPPGPQFQPMSQITGVKKLMHSSSLSDSSIPRFGVKTNQ
EELLAQELENLNKWGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFRIPVDTMVTYMLT
LEDHYHPDVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVS
NQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMV
LATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLEL
YRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLV
HPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEEPRGPGHPPPPDKFQFELTLEEEDEEEV
STAPGAFTVQGLSVAQDASPAEELLEVDGQDMPTEGKVQEPCCTQQADSAGSVAAGKDKA
TSPDASVDAVGRSSPLALSAESPLPPALRTPPPPEDTPGLPGLPSTAAEAGAQKEHQAAK
RACSACTGTSGEDPPPLPAPGGWGSAGGPT
NT seq
2433 nt
NT seq
+upstream
nt +downstream
nt
atgcgctcgggtacagcgcctcgggcaaggccccggccccctgacctgacactgcccccc
gcgggccctgagtccctggcccacttctccttcagcgacgaggacacctgttggcaccct
ccaggcagacctgtcagcttcgaggcggagaatgggcccacgccatctcctggccgcagc
cccctggactcgcaggcgagcccgggcctcgtgctgcacgccgggggggctatcagccag
cgccgggagtccttcctgtaccgctcggacagtgactacgacatgtcacccaaaaccatg
tcccggaactcgtcggtcaccagcgaggcgcacgctgaggacctcattgtgacacctttc
gcccaggtgctggccagtctccggagtgttcgcagcaacttctcactcctgaccaatgtg
cccattcccagcaacaaacggtccccgctgggcggcccaacccccgtctgtaaggccacg
ctgtcagaagagacatgtcaacaactggcccgggagacactggaggagctggactggtgc
ctggagcagctggagaccatgcagacctaccgctccgtgagcgagatggcatctcacaag
ttcaagaggatgttaaaccgtgaactcacacacctgtcagagatgagcaggtcaggaaac
caggtctctgagtacatctccaccacattcctggacaagcagaatgaagtggagattcca
tcacccacgatgaaggatcgagaaaaacagccagctccccgccagagaccttcccagcag
cccccgccccctgggccgcaattccagcccatgtctcagatcacgggggtgaagaagctg
atgcatagcagcagcctgagtgactctagcatcccccgctttggggtgaagaccaaccaa
gaagagctcctggcccaagaactggagaacctgaacaagtggggtctgaacatcttctgc
gtatccgaatacgccggaggccgttccctcagctgcatcatgtacacgatatttcaggag
cgtgacctgctgaagaaattccgcatcccagtggacaccatggttacatatatgctgacc
ctggaggaccactaccaccccgacgtggcctaccacaacagcctgcacgcggccgatgtg
ctgcagtccacccacgtgctgctggccacacccgcgctagatgctgtgttcacggacctg
gagattcttgccgccctcttcgcggccgctattcatgacgtagaccaccctggggtctcc
aaccagttcctcatcaacactaattcggagctggcgctcatgtacaacgatgagtcggtg
ctggagaaccaccacctggccgtgggcttcaagctgctgcaggaagacaactgcgatatc
ttccagaacctcagcaagcgccagcggcagagcctgcgcaagatggtcatcgacatggtg
ctggccacggacatgtccaaacacatgaccctcctggcagacctgaagaccatggtggag
accaagaaggtgaccagctcgggggtcctcctgctggacaactactccgaccgcatccag
gtccttcggaacatggtgcactgtgcagacctcagcaaccccaccaagccactcgagttg
taccgccagtggaccgaccgcattatggccgaattcttccagcagggggaccgtgaacgt
gagcggggcatggagatcagccccatgtgcgacaagcacacagcctcggtggagaagtct
caggtgggtttcatcgactatatcgtgcacccgctgtgggagacgtgggctgacctggtc
cacccggacgcccaggagatcctggacacgttagaggacaacagagactggtactacagc
gccattcgccagagcccatcaccgccgcctgaggaggagcccagggggccaggccaccca
cccccacctgataagttccagtttgagctgacgctggaagaggaagatgaggaggaggtg
tctaccgccccgggtgcatttacggtgcagggattgtccgtggctcaggatgcgtcccca
gctgaggaactcttggaggtcgatggccaggatatgcccacggaggggaaggtacaggaa
ccttgctgcacgcagcaagcagactcggccggtagtgtggctgcgggcaaggacaaggcc
acgtccccagacgcatccgtggatgccgtaggccgcagcagccccctggccctgtctgcc
gagagcccccttccgcccgccttgaggaccccgccccctccagaggacaccccgggcctc
ccgggcctcccctccacggcggccgaggcgggggcccaaaaagagcatcaggctgccaag
agggcgtgcagtgcctgcacaggaacgtccggcgaggacccccccccactcccagctcct
ggggggtgggggtcagctggaggccctacctga
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