Prionailurus bengalensis (leopard cat): 122490078
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Entry
122490078 CDS
T07574
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg00230
Purine metabolism
pbg01100
Metabolic pathways
pbg04927
Cortisol synthesis and secretion
pbg04934
Cushing syndrome
pbg05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
122490078 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
122490078 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
122490078 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
122490078 (PDE8B)
Enzymes [BR:
pbg01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
122490078 (PDE8B)
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GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PDE8
PAS_9
PAS
PAS_3
PAS_4
PAS_8
DUF3757
DUF4194
DHH
Motif
Other DBs
NCBI-GeneID:
122490078
NCBI-ProteinID:
XP_043448520
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Position
A1:141971306..142212205
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AA seq
890 aa
AA seq
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MGCAPSIHVSQSGVIYCRDSDESNSPRQTTSVSQGPAAPLHGLFVQTDAADVIPRSRASG
PPGAARVRRARTELGSGGSSGSSSAGSAAPATTTCRGRRRHCCSSAEAETQTSYTSVKQV
SSAEVRIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDK
HHEIIVIDHRQTRNFDAETVCRSIRATNPSEHTVILAVVSQASGDHEEASVLPLLHAGFN
RRFMENSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVN
PAFERMMGYHKGELLGKELAELPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSI
QQHVKITPVIGQGGKIRHFVSLKKLCCTTDNNKQIHKVHRDSGDNSQTESHSFRYKNRRK
ESIDVKSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEAL
DRVLEILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLA
MPITINDVPPCIAQLLDNEESWEFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLHCSET
TLRAWLQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVH
DVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDSKCNIFKNIDRNHYRT
LRQAIIDMVLATEMTKHFEHVNKFVNSINKPLAAEIEGSDCECNPTGKNFPENQILIKRM
MIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQIS
FIDYFITDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS
NT seq
2673 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtgcccccagcatccacgtctcgcagagcggcgtgatctactgccgggactct
gacgagtccaactcgccccgccagaccaccagcgtgtcgcagggccccgccgcccccctg
cacggcctcttcgtccagaccgacgccgccgacgttattccccggagccgcgcgtctgga
ccccccggggccgcccgcgtccgcagagcccgcactgagctgggcagcggcggcagcagc
ggcagcagcagcgctggctccgcagcccccgccacgaccacctgcaggggccggaggcgc
cactgctgcagcagcgcggaggccgagacccagaccagctacaccagcgtcaagcaggtt
tcttctgcggaggtacgcattgggcccatgagactgacacaggatcctattcaggttttg
ctgatctttgcaaaggaagatagtcagagtgatggattctggtgggcctgtgaccgagct
ggttatagatgcaatattgcccggactccagagtcagccctggaatgctttctagataaa
catcatgaaattatcgtaatagatcacagacagactcgaaactttgatgcagaaacagtg
tgcaggtcgatccgagccacgaatccctctgagcacacggtgatcctggcggtggtttcc
caagcatcaggcgaccatgaagaggcctcggtcctcccgctcctgcatgcaggcttcaat
aggagatttatggagaatagcagcataattgcttgctataatgaactgattcaaatagaa
cacggggaagttcgctcacagttcaaactacgggcctgtaattcagtgtttacagcatta
gaccactgtcatgaagccatagaaattacaagtgatgaccatgtgattcagtacgtcaac
ccagcctttgaaaggatgatgggctaccacaaaggcgagctcctggggaaagagctcgcc
gagctgcccaaaagtgataagaaccgggcagaccttcttgacaccatcaacacgtgcatc
aagaagggcaaggagtggcagggggtttactatgccagacggaaatccggggacagcatc
cagcagcacgtgaagattaccccagtgattggccaaggagggaaaattaggcattttgtc
tccctcaagaagctgtgttgtaccactgacaataataagcagattcacaaggttcatcgt
gattcaggagacaattctcagacagagtctcattcatttagatacaagaacaggaggaaa
gagtccattgatgtgaaatcgatatcatctcgaggcagtgatgcaccaagcctccagaat
cgtcgctatccatccatggcaaggatccattccatgaccatcgaggctcccatcacaaag
gttataaatataatcaatgcagcccaagaaaacagccctgtgacagtagcagaagccttg
gatagagttttggaaattttacggaccacggaactgtattcccctcagctcggaaccaaa
gatgaagatcctcacaccagtgatctcgttggaggcctgatgaccgatggcttgagaagg
ttgtcaggaaacgagtatgtgttcactaagaatgtgcaccagagtcacagtcatcttgcg
atgccaataaccatcaacgatgtccccccttgtatcgctcaattacttgataatgaggaa
agttgggagttcaacatctttgaattggaagctgttacacataaaaggccattggtttac
ctgggcttaaaggtattttcccggtttggagtctgtgaatttttacactgttctgaaact
actcttcgggcctggctccaagtgattgaggccaactaccactcttccaatgcttatcat
aactccacccatgccgccgatgtcctgcacgccactgccttcttcctcggaaaggaaaga
gtaaagggaagcctcgatcagctggatgaggtggcagcgctgattgccgccacagtccac
gatgtggatcacccgggaaggaccaactcgttcctgtgcaacgcaggcagtgaactcgct
gtgctctataatgacaccgctgtcctggagagtcaccacaccgccctggccttccagctc
acggtcaaggacagcaaatgcaacattttcaagaacattgacaggaaccattatcgaaca
ctacgccaggctattattgacatggttttagcaacagagatgacaaaacactttgaacat
gtgaacaaatttgtgaacagcatcaataagcccctggcggctgagattgagggcagtgac
tgtgaatgcaaccctacagggaagaactttcctgaaaaccaaattctgatcaagcggatg
atgatcaagtgtgctgatgtcgccaacccatgccgccccctggacctgtgcattgaatgg
gctgggaggatctctgaggagtattttgcacagactgatgaagagaagagacaggggctc
cctgtggtgatgccagtgtttgaccggaatacatgtagcatccccaaatcccaaatctct
ttcattgactacttcataacagacatgtttgatgcttgggatgcctttgcccatctgcca
gccctgatgcaacatttggctgataactacaaacactggaagacattagatgacctaaag
tgcaaaagtctgaggcttccatctgacagctaa
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