Prionailurus bengalensis (leopard cat): 122490108 Help Entry 122490108         CDS       T07574                                  Symbol SYNE1 Name (RefSeq) LOW QUALITY PROTEIN: nesprin-1   KO K19326   nesprin-1 Organism pbg  Prionailurus bengalensis (leopard cat) Pathway pbg04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:pbg00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     122490108 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:pbg03036]     122490108 (SYNE1) Chromosome and associated proteins [BR:pbg03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     122490108 (SYNE1) SSDB OrthologParalogGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 SYNE1 CH KASH Spectrin_SYNE1_2 SR_desmoplakin_3 SYNE3 Motif Other DBs NCBI-GeneID:  122490108 NCBI-ProteinID:  XP_043448563 LinkDB All DBs Position B2:complement(137072536..137544606) Genome browser AA seq 8829 aa AA seqDB search MAASRTASRSPRDIANVMQRLQDEQEIVQKRTFTKWINSHLTKRKPPLVVDDLFEDMKDG VKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKSMYRGSPIKLVNINSTD IADGRPSIVLGLVWTIILYFQIEELTSNLPQLQSLPGSTSSVDSMVSAETASPPSKRKVA TKIQGNAKKALLKWVQYTVAKQTGIDVKDFGRSWRSGVAFHSVIHAIRPELVDLEKVKGR SNRENLEEAFTIAESELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNTGTDGQ ENDEILPGFPSFANSIQNFKREDGLILKETKVWIEQFERDLTRAQMTESNLQDKYQSFKH FRVQYEIKRKQIEHLIQPVHRDGKLSLDQALVKQSWDRVSSRLFDWHIQLDKSLPAPLGT IGAWLYRAEVALREEITIQQVHEETANTIQRKREQHKDLLQNTDAHKRAFHEIYRTRSVN GIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRR ESVELLLQNYISFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQ WRNLSVEVRSVRSMLEEVIANWDRYGNTVASLQAWLEDAEKMLNQSEHAKKDFFRNLPHW IQQHAAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYARADEMDRMKKEY ADCITILSDFATEAHKKLSEPLEVSFINVKLLIQDLEDIEQRVPVMDAQYKMITKTAHLI TKESSQEEANEMFATMSGLKERLTKVKECCPPLLYESQQLLIPLEELEKQMTFFYDSLAK IHEIMAVLEREAQSSALFKQKHQELSACQESCKKTVTQIEKGSQNVQKFVTLSSVLKHFD QTKLHRQIADAHGAFQNMVKKIGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEK GNPEDLLKKHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQG EAPYHLLHLKIDVEKNRFLASVEECRTELDRETTLVPQEGSEKILKEHRIFFSDKGPHHL CEKRLQLIEELCLKLPVRDPVRNTPETCHVTLKELRAAIDATYKKLVEDRDKWKDYTRRI SEFSSWISAKETQLKGFKNEPIDTANHGEIKHAVEEIRNGVTTKGETLNWLKSRLKILIE VSSENEAQKQGDELAKLSSSFKALIALLSEVEKMLSNFGDCVQYKEIVKSSLGELISDSK EVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQQGEGGMPGQVRDE LRKLESTLDSMEHSREKQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLE SLSSELEQTKEFSKRTEGIAVQAENLVKEASEIPLGPKNKQLLQQQAKTIKEQVKKLEDT LEEDIKTMEMVKNKWDHFGNNFETLSVWITEKEKELNALETSSSAMDMQINQIKVIIQET ESKIGCITELEEAAQSFAQFVTTGESARIKAKLTQIRRYWEELREHAQCLEGTILGHLSQ QQKFEENLRKIQKSVSEFEDKLADPIKICSSATETYKILQEHMDLCQALEALNSAVTTVS ASAQKVANRATSSVQEAAALQQRYEETRSRAKERQAVLENLLAHWQRLEKELSTFLTWLE RCEAIASSPEMDISADRVKVESELQSIQALQNELVSQASVYSNLLQLKESLFSVASKDDV KMMKLHLEQLDERWRDLPQIISKRINFLQSVVSEHQQFDELLLSFSVWIKLFLSELQTTS EISITDHQAAFARHKDHEVEAESKMGDLQRLRDHLAKLGALGRAEDLHLLQGKAEDCFQL FEEASQVVGRRQLALSQLAEFLQHHASLSGVLHRLRHTVETTDSMNKKQTDLLKKDLNRA IQDAKTLESTAISLDGILAKAQYHLKSGSSEQRTSCRSTADHLCFELERIQNLLGTKQSE ADALAVLKKAFQDQKEELLKSIEDIEERTDKERLKEPTRQALQQRLRVFNQLEDELNSHE HELCWLKDKAKQIAQKDVAFASEVDREINRLEVTWDDTKKLIHENQGQCCGLIDLMRDYQ NLKSVVSKVLENANNVLATRTTVKDQEDLKWALSKHESVKNEMCNKQKELDNFTSKGKQL LSELKKIHSSDFNLVKTDMESTVDRWLDVSEKIEENMDRLRASLTIWGDVLSSKDEIDGW SNNSVPQLAESISNLNNSVRAEEFLKEFESEVKNKALRLEELHCKVNDLKELTKNPETPP DLQFIEADLRQKLEHAKEITEEAKGTLREFTTQSTQVEKFINDITSWLTKVEEVLMNCAQ TETWEGLKKVKEIQKELQSQQSNISSTQENLNSLCRKYHSMELESLGSAMTGLIKNHEAV SQLCSKTQASLQDFLEKHFNESMQEFQEWFSGIKAAAKKSSDRTGDSKVLEAKLHDLQNI LDSISDGQSKLDAVTQEGQTLYAHLSKQIVSSIQEQVTKANEEFQAFLKQCLKDKQALQD CALELGSFEDQHRKLNLWIHEMDERLSTENFGESKQHIPEKKNEVHKVEMFLGELLAVRE SLDKLSQRGQLLSEEGHGAGKEGRLCSQLLTNYQNLLRTTKEKLRNCQLALQEHEALEEA VQSMWSWVKDIQDKLACAESTVGSKDTLEKRLLQIQDILLMKGEGEVKLNMAIGKGEQAL RSSNKQGQKVIQTQLQNLKDVWADIMSSSLRAQSTLESVISKWNDYLEGKNQLEQWMEFV DQKVEHPLQPQPGLKEKFSLLDHFQSIVSEAEDHAGTLHRLASKSRELYQKTEDESFKET AQEELKTQFNDIITVSKEKMRKVEEIVKDHLMYLDAVQEFTDWLHSAKEELHRWSDMSGD SSATQKKLSKIKELMDSRGIGASRLSRVESLAPAVRQNTSASGCELVDAEMQALRADWKQ WEDSVLQTRTSLENLVSQMALSEQEFSGQVVQLEQALEQFGALLTTCAQQLALLESKNTD KEIVECWRKGQEILDALQKAEPKTEDLKSQLNELCRFSRDLSTYSGKVSGLIKEYNCLCL QASKGCQTREQILQQRFQRAFKDFQQWLVNAKITTAKCFDIPQNISEVSTSLQKIQEFLS ESENGQHKLNVMVSKGELLSTLLPKEKADGIQAKVATAKEDWKKFHSNLHQKESALENLK IQMKDFEVSAEPVQDWLSKTEKLVQESSNRLYDLPAKRREQQKLQSVLEEINCYEPQLNR LREKAQQLWEGQAASKSFMHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKEL HDWMTDAVHMLDSYCHPISDKSVLDSRMLKLEALLSVKQEKEIQMKMIVTRGESVLQNTS PEGWPAIQQQLQSVKDMWASLLSAAIRCKSQLEGALSKWTSYQDDVRQFSSWMDSVEASL NESERQYAELREKTASLGKAKLLSEEVLSYSSLLEAIELKGAGMTEHYVTQLEFQDLQER YRAITERAKEAVTKSEKLVRLHQEYQRDLKAFEVWLGQEQEKLDRYSVLEGDAHTHETTL RDLQELQVHCAEGQVLLNSVLHTREEVIPSGIPQTEDRALESLRQDWQAYQQRLSETRTQ FNNVVNKLRLMEQKYQQVDEWLKTLEDKVSLRTGRQSNRAAKEIQLHQMKKWHEEVIAYK DEVEDVGARAQEMLDENHVSSSMGCQATQLTSRYQALLLQVLEQIQFLEEEIQSLEESEL SLSSYSDWYSSTHKNFKNVATKIDRVDKATMGKKMKTLEGLLKDMDKGHSLLKSAREKGE RALKYLEDGEAEMLRKDIHEHVEQLKELTSTVRKEHMTLEKGLLLAKEFSDKYKALTQWI SEYQEILHTPEEPKMELYEKKAQLSKYKSLQQMVLSHEPSIKSVREKGEALLELVQDVTL KDKMDKLQSDYQDLCGAGKEHVCSLETKVKDHEDYNSELQEVEKWLLQMSGRLVAPDLME TSSLETITQQLAHHKAMMEEIAGFEDRLNNLKSKGDNLISQCADHLQAKLKQNVYAHLQG TKDSYSAVCSTAQRVYQSLEHELQKHVSRQDTLQQCQAWLSAVQPDLKPTQHPPLSRAEA VKQVKHYRALQEQARTYLDLLCSTCDLSSSSVKTTAKDIQETEQMIEQRLVQAQNLTQGW GEIKHMKAELWIYLQDADQQLQNMKKRHSELELNIAQNMVSQVKDFVKKLQCKQASVTAI TERVNKLTKKQESPEHKEISHLNDQWLDLCLQANSLCLQREEDLQRTRDYHDRMNVVEEF LEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKQAVEDLKDQKQKMIEHLNLDDKE LVKEQTSHLEQRWFQLEDLVKRKLQVSVTNLEELNVVRSRFQELMEWAEEQQPNIAEALK QSPPPDMAQNLLMDHLAICSELETKQMLLKSLIKDADRVMADLGLNERQIIQKALSDAQR HVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDDVSKQ VKTCKSAQASLKTYQNEVTGLWAQGRELMKGATEQEKSEVLGKLQELQSVYDTVLQKCSH RLQELEKSLVSRKHFKEDFDKACHWLKQADIITFPEINLMNESTELHAQLAKYQHILEQS PEYENLLLTLQRTGQAILPSLNEVDHSYLNEKLNALPLQFNVIVALAKDKFYKVQETILA RKEYASLIELTTQSLSELEDQFLKMSKVPTDLRVEEAVSLQEGCRALLGEVARLGEAVDE LNQKKESFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVGLLEDTSSAYQEHEKMCHQLEK QLQAVKTEQSKVNEETLPAEEKLKIYHSLAGSLQDAGIVLKRVTVHLEDLVPHLDPSAYE KAKQQIQSWQEELKVLTSAIGATVTECESRMVQSIDFQTELSRSLDWLRSVKAELSGPVC LDLSLQDIQEEIRKTQIHQEEVQSSLRIMNALSNKEKEKFTKAKELLSADFQHTLAELSE LDGDVQEALRTRQAALTQIYSQCQRYYQVFQAANDWLEDAHEMLQLAGNGLDVESVEENL KNHVEFFSTEDQFHSNLEELQHLVASLDPLIKPTGKEHLAQKMASLEEKSQRIIQDSHAQ LDLLQRCADQWQNYQKAREEVIELMNEAEKKLSEFSLLKTSSSHEAEEKLSEHKALASVV NSFHEKVVALEDKTSQLEKTGNDASKAAISRSMTTVWQRWTRLRAVAQDQEKILEDAVDE WTSFNNKVKKATETTDQLQDKLPGGSAEKASKAELLTLLDHHDALVLELEQQQLALGMLR QQALGMLQDGAPQPPGEEPPTVQEITAMQDRCLNMQEKVKNTGKVVKQELKEREVVETQI NSVKSWVQETKEYLGNPTIEIDAQLEELQLLLTEATNHRQSIEKMAEEQKNKYLGLYSIL PSELSLQLAEVALDLGTIHDQIQDKVREVEQSKAMSQEFSRQIQKIAKDLTTILSKLRAK TDNLQQAKIDQKVLGEELDGCNLKLMELDAAVQKFSEQNGQLGKPLAKKVGKLMELHQQT IRQAENRLSKLSQAASHLEEYTEMLEFILKWIEKAKVLVHGKIAWNSANQLREQYIFHQT MLEESEEIPSNLEAMIEKLQCLASIYSTEKMSQQVADLGRESEELRQTIKIRLQNLQDAA KDMKKFETELKNLQVALEQAQTTLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVHAVQI CQSALRIPDDVVASLPLCHCALHLQAEASRLQHTAIQQCNIMQEAVVQYEQYEQEMQHLQ ELIEGAHREIEDTPAATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKH ATMLLTVTEVEGLAEGTEDLDRELLPATSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNS EISSPPACRSPSPVANTDASVNQDIAYYQALSAERLQTDAARIHPSTLPSPEFYELGLEP SATAKLDDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIEMKLSESLE HDRGPESQMAEHQALMDEILMLQEEISELQSSLAEELVSQSPESDPAEQLALQSTLTVLA ERMSTIKMMASGKRQLLEEKLNDQLEEQRQEQALQRYRCEADELDHWLLSTKATLDTALG TAQEPMDMEAQLVDCQNMLVEIEQKVVALSELSVHNDNLLLEGKAHTKEEAEQLAVKLRT LKGSLLELQRALHDKQLLMQGTAQEKEESHADLTASQSPGVQEWLAQARTAWAHQRQSSL QQQKELEQELAEQKSLLRSVASRGEEILTQHSAAETSAGIGEKPDVLSQELGMEGEKSAS EDQMRMKWESLHQEFSTKQKLLQNVLEQEQEQVLYSRPNRLLSGVPLYKGDGQTQDRSAV TSLLDGLNQAFEEVSSQGGGTKRQNIHLEQKLYDGVSATSTWLDDVEERLFVATALLPEE TEACLFNQETLAKDIKEMSEEMDKNKNLFSQAFPENGDNRDVIEDTLGCLLGRLSLLDSV VNQRCHQMKERLQQILNFQNDLKVLCTSLADSKYIILQKLANVFEQPVAEQIEAIQQAED GLKELDAEIIELKKHGDKLQIEQPSMQELSKLQDMYDELMMTIGSWRSSLNQNLALKSQY ERALQDLADLLETGQEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETLFRKI INFAVLQETQFHTELMTQASAVLKRAHKRGVELEYILETWSHLDEDHQALSKQLEVVESS IPSVGLVEESEERLIDRITLYQHLKSSLHEYQPKLYQVLDDGKRLLISISCSDLESQLNQ LGEQWLDNTNKVSKELHRLETVLKHWTRYQSESAELIHWLQSAKDRLEFWTQQSVTVPQE LEMVRDHLNAFLEFSKEVDAKSSLKSSVLSIGNQLLRLKKVDTASLRSELSHIDSQWTDL LTNIPTVQEKLHQLQMDKLPSRHAISELTTWISLMENVIQKDEENIKNSIGYKAIHEYLQ KYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQGLVT EKIQLLEGLLESWSEYENNVQSLKTWYETQEDKLKQQHRIGDQASVQSAMKDCQDLEDLI RAKEKEVEKIEQNGLALIQNKKEEVSGVVMSTLRELNQTWANLDHMVGQFKILLKSVFDQ WNNHKEAFDEINSYLMEARYSLSRFRLLTGSLEAVQVQVDNLQNLQDDLEKQEKNLQNFG SITNQLLKECHPPVTETLTTTLKDVNMRWNNLLEEIAKQLCSSKALLQLWQRYKDYSKQC ASTVQQQEDGASELLKAATNKDIADDEAATWIQDCNDLLKGLGTVKDSLFVLRELGEQLK QQVDASAASTIQSDQLSLSQRLCALEQALCKQQTMLQAGVLDYETFTKSLEALEAWIVEA EEILQGQDPGHSSDLSTIQQRMEELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQ NLNRHWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLL EQQRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRA QQRRGIIDSQIRQWRRYREMAEKLRKWLVEVSYLPVSALGSVPIPLQQARTLFDEVQFKE KVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKWRSASVRLEERKKKLAFL LKDWEKCENGIADSLEKLRTFKKKLSPPLPDHHEELHAEQMRCKELENAAGNWTDDLAQL ALLKDTLCAYISADDISILNERMELLQRQWEELCHQLSLRRQQVSERLNEWAVFSEKNKE LCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAVAQENKIQLQQMGERLARASHESK ASEIEYKLGKVNDRWQHLLDLMAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKP IVYDSCDSDEIQKKLTEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQ ATRNLDRRWRNICAMSMERRLRIEETWRLWQKFLDDYSRFEDWLKISERTAAFPSSSGVL YTVAKEELKKFEAFQRQVHESLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDN LQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKA FQQEISLNHNKIEQIISQGEQLIEKSEPLDAAVIEEELDELRRYCQEVFGRVERYHKKLI RLPLPDDEHDLSDRELELDDSAALSDLHWRDTSADSVLSPQPSSNPSLSLAQPLRSERSG RDTPASVDSIPLEWDHDYDLSRDLESAVSRTLPSEDEEAGDDKDFYLRGAVGLSDVMIPE SPEAYVKLTESAIRNTSGAPSALESQIRQLDKALDESRFQMQQTENIIRSKTPTGPELDS SYRGYMKLLGECSGSIDSVRRLEHKLKEEEENFPGFVNLNSTETQTAGVIDRWELIQAQA LSKELRMKQNLQKWQQFNSDLNNIWTWLGETEEELERLQHLELSTDIQAIELQIKKLKEL QKAVDHRKAIILSINLCSPEFTQTGSEKSQDLQDRLSQMNGRWDRVCSLLDEWRGLLQDA LMQCQDFHEMSHGLLLMLENIDRRKNEVVPIDSNQDAETLQDHHKQLMQIRHELLESQLQ VASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDMSSSQQD LSSWSSADELDTSGSVSPTSGRSTPNRQRTPRGKCSLSQPGPSVNSPHSRSIKGGCDSSL SEPRPARSGRAFLLRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPML RYTNGPPPL NT seq 26491 nt NT seq  +upstreamnt  +downstreamnt atggctgcctccaggacggcctcacggtctccccgggacatcgccaatgtgatgcaaagg ttgcaagatgagcaagagatagtacaaaaacgtactttcacgaaatggatcaactcgcat ctgaccaagcggaaacccccactggtggtagatgatctttttgaagacatgaaagatggc gttaagctgcttgctcttctggaggtcctgtccgggcagaaactgccttgtgaacaagga cgccgtatgaagcgaatccatgctgtggctaatattggcacagcactgaagttccttgaa ggaaggaagtccatgtacagaggatcaccgattaaactagtcaacattaactccaccgat atagcagatggccggccatcaatagttctcggattggtgtggaccattattctgtatttc cagattgaggagctgaccagcaacctgccgcagctgcagtccctgcctggcagcacatcc tctgtggacagcatggtcagcgcggagaccgccagccccccgagtaagcggaaggtggcc accaagatccaaggaaatgctaagaaggctttattaaagtgggttcagtacacagtagcc aagcagacgggaatagacgtaaaggacttcgggcggagttggagaagtggagttgccttt cattcggtcatccatgccattcgaccagaactagtggacttggagaaagtgaaaggcaga tctaaccgggaaaacctggaggaagctttcactattgctgaatcagaactaggaattcca agactactggatcctgaagatgttgatgtggataaaccagatgagaagtctattatgacc tatgtagcccagtttctgaagcattaccctgacatccacaacacaggcactgatgggcaa gagaatgatgaaatacttccaggttttccatcttttgcaaattctatccaaaattttaag agagaagacgggctaattttgaaggaaacaaaagtctggatagaacaatttgaaagagat ttgacaagggcacagatgacggaatcaaatttacaggataaatatcagtcatttaagcac ttcagagttcaatatgaaataaaaaggaagcagatcgaacatttaatacaaccagtacat agagacggtaaattgtcacttgaccaagcattggtaaagcagtcctgggatagagtgtcc tccaggctctttgactggcatatacagcttgataaatctctccctgcacctctgggcacc ataggtgcctggttatacagagcggaggtggccctgagagaggaaataaccattcagcag gtgcacgaggaaacggccaacacaatacaacggaaacgcgagcaacacaaggatctgctt caaaacacagatgcccacaaaagagcattccatgaaatctaccggaccagatctgttaac gggatcccagtaccacctgatcaattagaggacatggccgagaggtttcattttgtttcc tccacatcagagctacacttaatgaaaatggaatttctagaattaaagtaccgtctgctc tcactgctggttcttgcagagtcaaagctgaaatcttggatcatcaagtatgggaggaga gagtccgtggagctccttctacagaactacatctcttttatagaaaatagcaagttcttt gaacaatatgaagtgacataccagatcttgaaacagacagctgagatgtacgtcaaagct gatggttcagtggaagaagctgagaatgtgatgaaattcatgaatgaaaccacagcccag tggaggaacctctcagtagaggtcaggagcgtgcgaagcatgctggaagaagtcatcgcg aactgggatcgatatggcaatactgtggctagtcttcaggcctggctggaggatgctgag aaaatgctaaatcaatcagagcatgccaaaaaggatttttttcgaaacttgcctcactgg atacagcagcacgctgccatgaatgatgctggcaattttctaattgaaacatgtgatgaa atggtttcccgagatcttaaacagcaattgctattgctcaatggacggtggagggaattg tttatggaagtcaagcaatatgctcgggctgatgagatggacagaatgaagaaggagtat gcagactgtattactatcctgtctgattttgcaactgaagcccataagaaactttctgaa cccttagaagtctcttttattaatgtcaagttattaattcaagacttggaggacattgag cagcgggtacctgtaatggatgctcagtacaagatgattaccaagaccgcacacctcatt accaaggagagctcccaagaagaagccaatgaaatgtttgcaaccatgtctgggctcaaa gaacggctaaccaaggtcaaagaatgttgccctccactcctttatgagtctcagcagctg ttgatcccattggaagaactggagaagcagatgacgttcttttatgactcgcttgcgaaa atccacgaaattatggcagttctcgagcgtgaagcacaatccagtgccctttttaaacag aaacatcaggaactgtcagcttgtcaagagagctgtaagaaaaccgtgacgcagattgag aaaggcagtcaaaatgttcaaaagttcgtgaccttgagcagtgtgttaaagcattttgat cagacgaagctgcacagacagattgcagatgcccacggtgctttccagaatatggtgaag aaaattggagactggaagaaacatgtggaaaccaatagtcgcttgatgaagaaatttgaa gagtctcgagcagagctggagaaggtgctacggattgctcaggagggcctggaggaaaag gggaacccagaagacctcctgaagaaacatacagaatttttcagtcagctggatcagaga gtgctcaatgctttcctgaaagcttgcgacgagctcactgacatcctccctgagcaggaa cagcagggcctgcaggaagctgttagaaagctccataaacagtggaaggaccttcaagga gaagccccatatcatttgcttcatctgaagattgatgtggagaagaatagattcctagct tctgtagaagaatgcagaactgagctggatcgagagaccacgctggtgccccaggaaggc agtgaaaagattcttaaggagcacaggattttcttcagtgacaaaggtcctcatcatctt tgtgagaaaaggttacagcttattgaagaactgtgtctgaaactccccgtccgggaccca gtaaggaacacacctgaaacctgtcacgtgactctcaaagagctcagagccgccattgac gccacctacaagaagctcgtagaagaccgggacaagtggaaggactacactagaagaatt tctgagttctcatcttggatatctgcaaaggagacacaattgaaagggtttaagaatgag cccatcgataccgccaaccatggagagattaaacatgccgtagaggagatcagaaatggt gttaccacaaagggtgagactctcaactggctgaaatccaggcttaaaattttaattgaa gtttcttctgagaatgaagcccaaaagcaaggagatgagttggcaaaattatctagttct ttcaaggctctcatagctttgttgtcagaggttgaaaagatgttaagcaactttggggac tgtgtccagtacaaagaaatagtcaaaagttcccttggagagttgatttctgactctaaa gaagtccaggagcaagctgagaagatcttggacactgaaaatctgtttgaagcacagcaa ttacttcttcatcaccagcaaaagacaaagaggatttctgcgaagaagagagacgtgcag cagcagatagcacaggctcagcaaggagaaggtgggatgcccggccaagtccgggacgag ctgcggaagctggagagcaccctggacagcatggagcacagcagagagaagcaggaacgc cgcatccaggtcacattaagaaagtgggagcgatttgaaacaaacaaagagacagtggtc agatacctttttcaaacaggttccagccatgagcgctttttgagttttagcagtttggaa agtttatcttcagaattggaacagacaaaggagttttctaaacgaacagaaggtattgca gtccaggctgagaatcttgtgaaggaagcttccgagataccacttgggcccaagaataag cagctgcttcaacagcaggccaagacaatcaaagagcaagtcaaaaaattagaagacaca cttgaagaagatattaaaaccatggaaatggtgaaaaacaagtgggatcattttggcaat aattttgagaccctgtccgtctggataactgagaaagaaaaagaactcaatgccttggaa acttcatcatctgccatggacatgcaaatcaaccagattaaggtcataattcaggaaaca 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ccagacaaccctgacttccccagaagtcggacgtcttagtctgaaggaacaactttcaca tcgacagcatctgctatctgagatggagtcactcaagccaaaggtccacgccgtgcagat ctgccagagtgccctccggatccccgacgatgtggtcgccagcctgccgctctgccattg tgccttgcacctgcaggcagaggccagccgattgcagcacacggctatccagcagtgcaa catcatgcaggaggctgtggtacaatatgaacaatatgagcaagaaatgcagcacctcca ggagcttatagaaggagctcacagagagattgaggacacacccgcggccaccagcaacat ccaggagctgcaagcccagatttctcggcatgaggagctggctcagaaaatcaagggcta ccaggagcagatcgcctctttgaactccaagtgcaagatgctgacgatgaaagccaagca tgccaccatgctgctgacggtgacggaggtggaggggctggcggaggggacggaggacct ggaccgggagctcctccccgcgacctcggcccacccctctgtggtcatgatgactgcggg tcgctgtcacactttgctgtcacctgtcacagaggagtctggggaggagggaaccaacag tgaaatttcttctccacctgcctgtcgctccccttcacctgtggctaatacagatgcttc tgttaaccaggacattgcttattaccaggccttatctgctgagaggttgcagacagatgc tgccaggatccaccccagcacgttgccatcgccggagttctatgaactaggactggagcc atctgctaccgctaagctggatgatttgcagcgttcttgggaaaccctaaagaatgtgat cagtgaaaagcagcgcactctctatgaagctttggaaaggcagcagaagtaccaggactc cctccagtccatctccacaaaaatggaggccatcgagatgaaactcagtgagagtctgga gcacgacaggggtccagagagccagatggcggagcatcaggcactgatggatgagattct catgcttcaagaggagatcagtgagctccagtcgtctctggcggaggagctggtgtccca gtctcccgagtccgaccccgcggaacagctggccttgcagtccacactcaccgtcttagc cgagcggatgtccaccatcaagatgatggcgtcagggaagcgacagcttttggaggagaa gttaaatgatcagcttgaggaacagagacaggagcaggccctgcagaggtaccgctgtga agccgacgagctggaccactggctcctgagcaccaaggccactctggacaccgcactggg tacagcccaggagcctatggacatggaagcccagctggtggattgccagaacatgctagt ggaaatcgagcagaaggtggtggccttatcagagctgtcggtccacaatgacaacctgct gctggagggcaaggcccacaccaaggaggaggcagagcagctggccgtgaagctgagaac cctcaagggcagcctcctggagctgcagagagccctacatgacaaacagctcctcatgca gggaacagcccaagagaaggaggagagccatgccgacctcaccgccagtcagagccccgg tgtccaggaatggctggcccaagcacggactgcatgggcccaccagcgacagagcagtct ccagcaacaaaaagagttggaacaggaattagcagagcagaagagcctcctgcggtcagt agccagtcgtggagaggaaattctcacccaacactcagctgcagagacctctgctggtat tggcgaaaaacctgatgtgttatcccaggagttggggatggaaggggagaaatcagcctc tgaagaccagatgagaatgaaatgggaaagcctacatcaagaatttagtaccaagcagaa actactacagaatgttctggaacaggaacaagagcaagtgctctacagcaggccaaatcg gctcctgtctggcgtgccactctacaaaggggatgggcagacccaagacagatctgcagt gacgtctttactggatggattgaaccaggcgtttgaggaggtttcgtcccagggtggggg gacaaagaggcagaacattcacttggaacagaagttatatgatggggtctcagctacctc tacatggttggatgatgtggaggaacgcttatttgttgccacagcacttttaccagaaga aaccgaagcttgcctcttcaaccaagagactcttgccaaagatattaaggaaatgtctga agaaatggataagaacaagaacttgttttcccaagcatttccagagaatggtgataaccg agatgttattgaagacactttgggttgtcttttgggccggttatccttgttagactcagt agtgaatcagcgatgtcatcagatgaaggaaagacttcagcaaatactaaattttcagaa tgatctgaaggtgctgtgtacatcattggccgacagcaaatacatcattctgcagaaact ggcaaatgtgtttgaacagcccgtggcagagcaaattgaggcaatacaacaggctgaaga tgggctaaaggagttggatgcagaaatcattgaattgaaaaagcatggtgacaagttgca gattgagcagccttccatgcaggaactgtccaaacttcaggacatgtatgatgaactgat gatgaccattggctcctggcggagtagtctgaaccagaatcttgccctcaagagtcagta cgaaagggccctacaagatctggctgacctgctggagactggacaggagaagatggcagg tgaccagaaaatcattgtgtcttccaaggaggaaattcaacaactgcttgacaaacataa ggaatactttcaaggcctggaatctcatatgatcctgacggagacactcttcagaaagat aatcaactttgcggtcctacaagaaacgcagttccacacagaactgatgacacaggcttc agctgtactgaaacgggctcacaagaggggtgtggagttggagtacattctagagacatg gtctcatctggatgaagaccaccaggcgctcagcaaacagctggaggtggtggaaagtag catcccaagtgtgggattggtggaggagagcgaggagaggctcatcgaccggataacact ctaccagcatttgaaatccagccttcatgaataccagcccaaattatatcaggtgttaga tgatgggaaacgactgctcatatccattagctgctcagatctagaaagccagctcaatca actgggagaacagtggttggataataccaacaaagtgtcgaaggaacttcaccgattgga aacagtactgaaacactggaccagatatcaaagcgaatctgcagaacttattcactggtt acagtctgcaaaagacaggctagaattttggactcaacagtctgtgacagtcccacaaga actggaaatggtccgtgatcatctaaatgctttcctggagttttccaaagaagtggatgc gaaatcttccctgaaatcatctgttctgagcatcggaaatcagcttcttcgattaaagaa agtggacacggcttccctacgttcagaactgtcacacattgacagccagtggactgatct gctgacaaatattccgactgtacaggaaaagctccaccagctccagatggataagctgcc gtcccgccatgccatttctgaactgacgacttggatttctctaatggaaaatgttattca aaaggatgaagagaacataaaaaattcgataggttacaaggcaattcatgaataccttca gaaatacaagggttttaagatagatattaactgtaaacagttgacagttgattttgtgaa tcagtccgtgctacaaatcagcagtcaggatgtggaaagtaaacgcagtgacaagactga ttttgctgagcaacttggagccatgaataaaagttggcaaatcctgcagggcctagtgac tgagaagatccagctgttggaaggcttattggaatcttggtcagaatatgaaaataatgt gcaaagtctgaaaacttggtatgaaacccaggaagacaaactaaaacaacagcatcgaat tggagatcaggcttcagttcaaagcgcaatgaaagactgtcaggatctagaagatttgat tagagcaaaagaaaaagaagtagagaaaattgagcagaatggacttgctttgattcagaa caagaaagaagaagtctctggtgttgtcatgagcacgctgcgggagctcaaccaaacctg ggcaaatttagaccacatggttgggcagttcaagatactgttgaagtccgtgtttgacca atggaacaatcacaaggaggcctttgatgagataaacagttacctcatggaggccagata ttctctttcccgcttccgcctgctgactggttctttagaagctgtacaagttcaggtaga caatcttcagaatcttcaagatgatctggaaaaacaggaaaagaacttacagaattttgg ttccatcaccaaccaactgttaaaagaatgtcacccacctgtgacagaaactcttaccac cacattaaaagatgtcaatatgagatggaataacttgctggaagagattgccaagcagct gtgctccagcaaggctctccttcaactttggcaaagatacaaggactactccaaacagtg tgcttctacggttcagcagcaggaggatggagccagtgagctcctgaaggcagccactaa caaggacattgccgatgacgaagctgcgacgtggattcaggattgcaacgatctcctcaa aggcttggggacagtgaaggattccctttttgttctccgtgagctgggagagcagctcaa gcaacaagtggatgcttcagcggcatcaaccattcaatccgatcagctgtccttgagtca acgcttatgtgccctagaacaggctctctgcaagcagcagaccatgttacaggctggagt tcttgactatgaaacctttaccaagagtttagaagctttggaggcctggatagtagaagc ggaagaaatattgcaagggcaggaccctggccactcttctgacctctcgaccatccagca aaggatggaagaacttaagggacagatgttaaaattcagcagcatggccccagatttaga ccgtctaaatgagcttggatataggctacccctgaatgataaagaaatcaaaaggatgca aaatctgaaccggcactggtctctgatctcctctcagacaacagagagattcagtaagtt gcagtcgtttttgctacaacatcagactttcttggaaaaatgtgaaacatggatggaatt cctggttcaaacggaacaaaagttagcagtagagatttctggcaattatcagcatctttt ggagcagcagagagcacatgagttgtttcaagcagagatgttcagtcgtcagcagatttt gcactcgatcattattgatgggcagcgtcttctagaacaaggtcaagttgatgacaggga tgaattcaacctgaaactgacccttctcagcaatcagtggcagggagtgattcgcagggc ccagcaaaggaggggcatcatcgacagccaaattcgccagtggaggcggtacagggagat ggcagaaaagcttcgtaaatggttggttgaagtgtcctatcttcccgtgagtgctctcgg aagtgtcccaataccactgcagcaggcaaggaccctctttgatgaagtgcagttcaaaga aaaagtgttcctgcgacaacaaggcagctacatcctaacagtggaggctggcaagcagct tctgctctcggccgacagtggagctgaggccgccttgcaggcggaacttgctgaaatcca agagaaatggagatcggccagtgtgcgtctggaggaacggaagaaaaagctggccttctt gctgaaagactgggaaaaatgtgagaatggtatagctgattctctggagaagctacggac tttcaaaaagaagctgtctccacccctgccagatcaccacgaagagctccatgcagagca aatgcgttgcaaggagttggaaaatgcagctgggaactggacagatgacttggctcagtt ggctctgctgaaggacaccctctgtgcctacatcagcgccgatgatatctccatcctgaa cgaacgcatggagcttctgcagagacagtgggaagaactgtgccaccagctctccttaag gcggcagcaagtgagtgagagattgaatgaatgggctgtcttcagtgaaaagaacaagga gctttgcgaatggctgacccagatggaaagcaaagtttctcaaaatggagacattctcat tgaagaaatgatagagaaactcaagaaggattatcaagaggaaattgctgttgcccaaga gaacaaaatacagctccagcaaatgggagaacgacttgctcgagccagccatgaaagcaa agcctctgagattgaatacaagcttggaaaggtcaacgaccggtggcagcatctcctgga tctcatggcagccagggtaaagaagctgaaggagaccctggtggccgtacagcagctgga taagaacatgagcagcctgaggacgtggctggctcacatcgagtcagagctggccaagcc catagtctacgattcctgtgactcggatgaaatacagaaaaagcttactgagcagcagga gcttcagagagacatcgagaaacacagcacgggtgtggcgtctgtcctcaacctgtgtga ggtcctgctgcatgactgtgacgcctgtgccacagatgcggagtgtgactccatccagca ggctacgcgaaacctggaccggcggtggaggaatatctgtgccatgtccatggagaggag gctcagaattgaagagacgtggcgattgtggcagaagtttctggacgattattctcgttt tgaagattggctcaagatttcagaaaggacagctgccttccccagctcttccggggtgct ctatacagttgccaaggaagaactaaagaaatttgaggctttccagcgacaggtgcacga gagcctgacccagctggagctgatcaacaagcagtaccgtcgcctggccagagagaaccg caccgattctgcctgtagcctaaagcagatggttcacgaaggcaaccagagatgggacaa cctgcagaagcgtgtcacctccatcttgcgcagactcaagcatttcatcggccagcgtga ggagtttgagactgcgcgggacagcattctggtgtggctgacagaaatggatctgcagct cactaatattgagcatttttctgagtgtgatgttcaagctaaaataaagcaactcaaggc cttccagcaggaaatctcactgaaccacaataagattgagcagataatttcccaaggaga acagcttatagagaagagtgagcccttggatgcagcggtcattgaggaggaactggatga actccgacgttactgtcaggaggttttcgggcgcgtggaaagataccataagaaactgat tcgcctgcctctcccagatgatgagcatgacctctctgaccgggagctggagctggatga ctctgcagctctctcggacctccactggcgggacacctctgcagacagcgtgctttcccc ccagccttcttccaacccctccctctcactcgcccagcccctgcggagcgagcggtcggg acgagacacccctgccagtgtggactcaattcccctggagtgggaccatgattatgacct cagtcgggacctggagtctgctgtgtccagaactctgccctctgaggatgaagaggctgg agacgataaagatttctacctcaggggagctgttggcttatcagatgtaatgatccccga aagtcctgaggcctatgtaaaactcacagaaagtgcaatcagaaatacctctggagcccc cagtgccttagagtcacagatccgacaactagacaaagccttggatgagagccgttttca gatgcagcaaactgaaaacatcatccgcagcaaaacccccaccggaccagagctagactc cagctacagaggctatatgaaactactgggtgagtgcagcggcagcatagactccgtgag gagactggaacacaaactgaaggaggaagaagagaactttccaggctttgttaacctgaa cagtacggaaacccaaacagctggtgtgatcgaccgatgggaactcatccaggcgcaggc cctgagcaaggagctgaggatgaagcagaacctccagaagtggcagcagttcaactctga cctgaacaacatctggacgtggctgggggagacggaggaggagctggagcggctgcagca cctggagctcagcaccgacatccaggcgatcgagctccaaatcaaaaagctcaaggagct ccagaaggctgtggaccaccgcaaagccatcatcctctccatcaacctgtgcagccccga gttcacccagactggcagtgagaaaagccaggatctgcaagatcgcctgtcccagatgaa cggacgctgggaccgcgtgtgctcgttgctggacgagtggcggggcctgctccaggatgc actgatgcagtgtcaggatttccatgaaatgagtcatggtttgcttcttatgctggagaa catcgacagaaggaaaaatgaagttgtccctattgattctaaccaggatgcagagacact tcaggaccatcacaagcagcttatgcaaataaggcatgagctattggaatcccaactcca agtggcctcactgcaagacatgtcttgccaactactggtgaatgctgaaggcacagactg tttagaagccaaagaaaaagtccatgtgattggaaatcggctcaaacttctcttgaagga ggtcagccgacacatcaaggagctggagaagttattagacatgtcaagcagtcagcagga tttgtcttcctggtcttctgcggatgaactggacacctcgggatctgtgagtcctacgtc aggaagaagcaccccgaacagacaaagaacgccacgaggcaaatgtagtctctcacagcc tggaccctctgtcaacagtccacatagcaggtccataaaaggtggctgcgattcctccct ttctgagcctcggccagctcggtccggccgggccttcttactcagagtcctccgcgcggc ccttccactccagcttctcctgttgctcctcatcgggctcgcctgcctcgtaccaatgtc agaggaagactatagttgtgccctctccaacaactttgcccggtcattccaccccatgct cagatacacaaacggccctcctccactctga

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