KEGG   Prionailurus bengalensis (leopard cat): 122490348
Entry
122490348         CDS       T07574                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
pbg  Prionailurus bengalensis (leopard cat)
Pathway
pbg01522  Endocrine resistance
pbg04010  MAPK signaling pathway
pbg04015  Rap1 signaling pathway
pbg04068  FoxO signaling pathway
pbg04071  Sphingolipid signaling pathway
pbg04114  Oocyte meiosis
pbg04148  Efferocytosis
pbg04218  Cellular senescence
pbg04261  Adrenergic signaling in cardiomyocytes
pbg04370  VEGF signaling pathway
pbg04380  Osteoclast differentiation
pbg04517  IgSF CAM signaling
pbg04550  Signaling pathways regulating pluripotency of stem cells
pbg04611  Platelet activation
pbg04613  Neutrophil extracellular trap formation
pbg04620  Toll-like receptor signaling pathway
pbg04621  NOD-like receptor signaling pathway
pbg04622  RIG-I-like receptor signaling pathway
pbg04625  C-type lectin receptor signaling pathway
pbg04657  IL-17 signaling pathway
pbg04658  Th1 and Th2 cell differentiation
pbg04659  Th17 cell differentiation
pbg04660  T cell receptor signaling pathway
pbg04664  Fc epsilon RI signaling pathway
pbg04668  TNF signaling pathway
pbg04670  Leukocyte transendothelial migration
pbg04714  Thermogenesis
pbg04722  Neurotrophin signaling pathway
pbg04723  Retrograde endocannabinoid signaling
pbg04728  Dopaminergic synapse
pbg04750  Inflammatory mediator regulation of TRP channels
pbg04912  GnRH signaling pathway
pbg04914  Progesterone-mediated oocyte maturation
pbg04917  Prolactin signaling pathway
pbg04926  Relaxin signaling pathway
pbg04932  Non-alcoholic fatty liver disease
pbg04933  AGE-RAGE signaling pathway in diabetic complications
pbg04935  Growth hormone synthesis, secretion and action
pbg04936  Alcoholic liver disease
pbg05014  Amyotrophic lateral sclerosis
pbg05020  Prion disease
pbg05022  Pathways of neurodegeneration - multiple diseases
pbg05132  Salmonella infection
pbg05133  Pertussis
pbg05135  Yersinia infection
pbg05140  Leishmaniasis
pbg05142  Chagas disease
pbg05145  Toxoplasmosis
pbg05152  Tuberculosis
pbg05161  Hepatitis B
pbg05163  Human cytomegalovirus infection
pbg05167  Kaposi sarcoma-associated herpesvirus infection
pbg05169  Epstein-Barr virus infection
pbg05170  Human immunodeficiency virus 1 infection
pbg05171  Coronavirus disease - COVID-19
pbg05205  Proteoglycans in cancer
pbg05208  Chemical carcinogenesis - reactive oxygen species
pbg05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pbg05415  Diabetic cardiomyopathy
pbg05417  Lipid and atherosclerosis
pbg05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pbg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    122490348 (MAPK14)
   04015 Rap1 signaling pathway
    122490348 (MAPK14)
   04370 VEGF signaling pathway
    122490348 (MAPK14)
   04668 TNF signaling pathway
    122490348 (MAPK14)
   04068 FoxO signaling pathway
    122490348 (MAPK14)
   04071 Sphingolipid signaling pathway
    122490348 (MAPK14)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    122490348 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    122490348 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    122490348 (MAPK14)
   04218 Cellular senescence
    122490348 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    122490348 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    122490348 (MAPK14)
   04613 Neutrophil extracellular trap formation
    122490348 (MAPK14)
   04620 Toll-like receptor signaling pathway
    122490348 (MAPK14)
   04621 NOD-like receptor signaling pathway
    122490348 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    122490348 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    122490348 (MAPK14)
   04660 T cell receptor signaling pathway
    122490348 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    122490348 (MAPK14)
   04659 Th17 cell differentiation
    122490348 (MAPK14)
   04657 IL-17 signaling pathway
    122490348 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    122490348 (MAPK14)
   04670 Leukocyte transendothelial migration
    122490348 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    122490348 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    122490348 (MAPK14)
   04917 Prolactin signaling pathway
    122490348 (MAPK14)
   04926 Relaxin signaling pathway
    122490348 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    122490348 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    122490348 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    122490348 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    122490348 (MAPK14)
   04722 Neurotrophin signaling pathway
    122490348 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    122490348 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    122490348 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    122490348 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    122490348 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    122490348 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    122490348 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    122490348 (MAPK14)
   05161 Hepatitis B
    122490348 (MAPK14)
   05171 Coronavirus disease - COVID-19
    122490348 (MAPK14)
   05163 Human cytomegalovirus infection
    122490348 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    122490348 (MAPK14)
   05169 Epstein-Barr virus infection
    122490348 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    122490348 (MAPK14)
   05135 Yersinia infection
    122490348 (MAPK14)
   05133 Pertussis
    122490348 (MAPK14)
   05152 Tuberculosis
    122490348 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    122490348 (MAPK14)
   05140 Leishmaniasis
    122490348 (MAPK14)
   05142 Chagas disease
    122490348 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    122490348 (MAPK14)
   05020 Prion disease
    122490348 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    122490348 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    122490348 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    122490348 (MAPK14)
   05415 Diabetic cardiomyopathy
    122490348 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    122490348 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    122490348 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    122490348 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    122490348 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pbg01001]
    122490348 (MAPK14)
Enzymes [BR:pbg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     122490348 (MAPK14)
Protein kinases [BR:pbg01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   122490348 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 122490348
NCBI-ProteinID: XP_043448904
LinkDB
Position
B2:34182165..34256921
AA seq 360 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGADLLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctcaggagaggcccacgttctaccggcaggagctgaacaagacaatctgggaggtg
ccggagcgttaccagaacctgtccccggtgggctccggtgcctatggctccgtgtgtgct
gcctttgacacaaaaactgggttacgtgtggcagtgaagaagctctccagaccgtttcag
tccatcattcatgccaaaaggacctacagagaactgcggttacttaaacatatgaaacat
gaaaatgtgattggtctgttggatgtttttacacctgcaaggtctctggaggaattcaat
gatgtgtatctggtgacccatctcatgggagcagatctgaacaacattgtgaaatgtcag
aagcttacggatgaccatgttcagttccttatctaccagattctccgaggtctcaagtat
atacattcagctgacataattcacagggacctgaaacctagtaatctagctgtgaatgaa
gactgtgagctgaagatcttggattttggactggctcgacatacagatgatgaaatgaca
ggctatgtggccactaggtggtacagggctcctgagatcatgctgaactggatgcattac
aaccagacagttgatatttggtcagtgggatgcataatggccgagctgttgactggaaga
acgttgtttcctggtacagaccatattgatcagttgaagctcattttaagactcgttgga
accccaggggctgatcttttgaagaaaatctcctcagagtctgcaagaaactacattcag
tctttgacccagatgccgaaaatgaactttgcaaatgtatttattggtgccaatcccttg
gcggtggacttgctggagaagatgcttgtactggactcagacaagagaatcacagcggcc
caagcacttgcacacgcctactttgcccagtaccatgatcctgatgatgaaccagtggct
gatccttatgatcagtcctttgaaagcagggacctccttatagatgaatggaagagcctg
acctacgatgaagtcatcagctttgtgcccccaccccttgaccaagaagagatggaatcc
tga

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