Prionailurus bengalensis (leopard cat): 122492061
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Entry
122492061 CDS
T07574
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
122492061 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
pbg03032
]
122492061 (TOP2B)
03036 Chromosome and associated proteins [BR:
pbg03036
]
122492061 (TOP2B)
Enzymes [BR:
pbg01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
122492061 (TOP2B)
DNA replication proteins [BR:
pbg03032
]
Eukaryotic type
DNA Topoisomerases
122492061 (TOP2B)
Chromosome and associated proteins [BR:
pbg03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
122492061 (TOP2B)
Centrosome formation proteins
Centriole proteins
122492061 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Motif
Other DBs
NCBI-GeneID:
122492061
NCBI-ProteinID:
XP_043451473
LinkDB
All DBs
Position
C2:complement(143078818..143143803)
Genome browser
AA seq
1681 aa
AA seq
DB search
GRRAARPPRRARPGVRPGSRRWGAGGGAARNTTSGAVGAEQRGPAARREAGAAAAASGPV
SGGTRHGQGGRRRRRGSRRQRGTDLGEQCCKKEESETANKNDSSKKLSVERVYQKKTQLE
HILLRPDTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKN
MTCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGG
RNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQP
DLSKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDE
TGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVV
KKKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKA
ASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTE
GDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKS
YDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKAS
KNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYA
GPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINK
ELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGE
QALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLSRLLFPAV
DDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLD
GLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLE
PMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMV
LFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQG
KITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTPSGPD
FNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQ
EREDILAGMAGKAIKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADASKKLLKRKK
GDLDTTAVKVEFDEEFSGTPVEGTGEEALIPSAPVNKGPKPKREKKEPGTRVRKTPTSSG
KSTAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDA
DDDEDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSSHDKKGQD
FGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDT
TAKPKRTPKQKKVETINSDSDSEFGIPKKSTPPKGKGRGAKKRKASGSENEGDYNPGRKT
SKTPSKKMKKTSFDQDSDVDIFPSDFTSEAPSLPRSGRARKEVKYFAESDDEEDVDFAMF
N
NT seq
5046 nt
NT seq
+upstream
nt +downstream
nt
gggcgccgggcggcgcggcctcctcggcgggctcggccgggcgtccgccccgggtctcga
cgatggggcgcggggggcggcgccgctaggaacacgacgagcggagcggtcggtgcggag
cagcgggggccggcggcccgcagggaagcgggagcggcggccgcggcctcggggcctgtg
agcggaggcacccgccatggccaaggcgggcggcggcggcggcgcgggagccggcggcaa
cggggcactgacctgggtgaacaatgctgcaaaaaagaagagtcagaaactgcaaacaaa
aatgattcttcaaagaagttgtctgttgagagagtgtatcagaaaaagacacaacttgaa
catattctccttcgtcctgatacgtatattgggtcagtggagccattgacacagctaatg
tgggtatatgatgaagatgtaggaatgaattgcagagaggttacctttgtgccaggttta
tacaagatctttgatgaaattttggttaatgcagctgacaataaacagagggataagaat
atgacctgtattaaagtttctattgatcctgaatctaacattataagcatttggaataat
gggaaaggcattccagtagtagaacacaaagtagagaaagtttatgttcctgcattaatt
tttggacagcttttaacatccagtaactatgatgatgatgagaaaaaagtaacaggtggt
cgcaatggttatggtgcaaaactttgtaatattttcagtacaaagtttacagtagagact
gcttgcaaagaatacaagcatagttttaagcagacatggatgaataacatgatgaaaact
tctgaagccaaaattaaacattttgatggtgaagattacacatgcataacattccaacca
gatctgtctaaatttaagatggaaaaacttgacaaggatattgtggccctcatgaccaga
agagcttatgatttggctggttcatgcaaaggggtcaaggtcatgtttaatggaaagaaa
ttgcctgtaaatgggtttcgcagttatgtagatctttatgtgaaagacaaattggacgaa
actggagtcgccctgaaagttattcatgaacttgcaaatgaaagatgggatgtttgtctc
acactgagtgaaaagggattccagcaaatcagctttgtaaatagtattgcgacaacaaaa
ggtggacgtcatgtggattacgtagtagatcaagttgttggtaaactgattgaagtagtt
aagaaaaagaacaaagctggggtatcagtaaaaccatttcaagtaaaaaaccatatatgg
gtttttattaattgccttatcgaaaatccaacttttgattctcagacgaaagaaaacatg
actctgcagcccaaaagttttgggtccaaatgccaactgtcagaaaaattttttaaagca
gcctctaactgtggcattgtagaaagtattctgaactgggtgaaatttaaggctcagact
cagctgaacaagaagtgttcatcagtaaagtatagtaaaatcaaaggtattcccaagctg
gatgatgctaacgatgctggtggcaaacattccctggagtgtacattgatactaacagag
ggagactctgccaagtcgctggctgtgtctggattaggtgtgatcgggcgagacagatac
ggagtctttccacttaggggaaaaattcttaacgtccgagaagcttcccataaacagatc
atggaaaatgcagaaataaacaatattatcaaaatagttggtctacaatacaagaaaagt
tatgatgatgcagaatctctgaaaactttacgctatgggaagattatgattatgactgat
caggatcaagatggttctcacataaaaggcctgcttattaatttcatccatcacaattgg
ccatcacttttgaagcatggttttcttgaagagttcattactcctattgtaaaggctagc
aaaaataagcaggaactttccttctatagtattcctgaatttgacgagtggaaaaaacat
atagaaaaccagaaagcctggaaaataaagtactacaaaggtttgggtaccagtacagct
aaagaagcaaaggaatattttgctgatatggaaaggcaccgcatcttgtttagatatgct
ggccctgaagatgatgctgccattactttggcattcagtaagaagaagattgatgacaga
aaagaatggttaacaaattttatggaagatcggagacagcgtaggttacatggcttacca
gagcaatttttgtatggtacagcaacaaagcatttgacttacaatgatttcatcaacaaa
gaattgattctcttctcaaactcagacaatgaaagatctataccatctcttgttgatggc
tttaaaccaggccaacgtaaagttttatttacctgtttcaagaggaatgataaacgtgaa
gtaaaagttgcccagttggctggatctgttgctgagatgtctgcttatcatcatggagag
caagcattgatgatgactattgtgaatttggctcagaactttgtgggaagtaacaacatt
aacttgcttcagccaattggtcagtttggaactcggcttcatggtggcaaagatgctgca
agccctcgttatattttcacaatgttaagctctttatcaagactgctttttcctgctgtg
gatgacaacctgcttaaattcctttatgatgataatcaacgtgtagagcctgagtggtat
attcctataattcccatggttttaataaatggtgctgagggcattggcactggatgggct
tgtaaactacccaactatgatgctagggaaattgtgaacaacgtcagacgaatgctagat
ggcttggatcctcatcctatgcttccaaactacaaaaactttaaaggaacgatccaagag
cttggtcaaaaccaatatgcagtcagtggtgaaatatttgtggtggatagaaacacagta
gagattacagagcttccagttagaacttggacacaggtatacaaagaacaggttttggaa
cctatgctaaatggaacagataaaacaccagcattaatttctgattataaagaatatcat
actgatacaactgtgaaatttgtggtgaaaatgactgaagagaagctagcacaagcagaa
gctgctggattacataaagtttttaaacttcaaactactcttacttgtaattccatggta
ctctttgatcatatgggatgtctcaagaaatatgaaactgtgcaagacattttgaaagaa
ttctttgatttacgattaagttattacggtttacgtaaggagtggcttgtaggaatgttg
ggagcagaatctacaaagcttaacaatcaagcccgtttcattttagagaagatacaggga
aaaattaccatagagaataggtcaaagaaagatttgattcaaatgttagtccagagaggt
tatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagaggaa
gaaacacaaaaccagcatgatgatagttcctctgattcaggaactccttcaggccccgat
tttaattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaactg
attaaacagagagatgcaaaagggcgagaggtcaatgatcttaaaagaaaatctccttca
gatctttggaaagaagatttagcagcatttgttgaggaactggataaagtggaggcgcaa
gaacgagaagatatcctggctggaatggctgggaaagcaataaaaggtaaagttggcaaa
cctaaggtgaagaaacttcagttggaagagacaatgccttccccttatgggagaagaata
gttcctgaaattactgctatgaaggcagatgccagcaaaaagttgctgaagaggaaaaag
ggtgatctcgataccacagcagtaaaagtagaatttgatgaagaattcagtggaacacca
gtagagggtacaggagaagaggcattgatcccgtcagctcctgtaaataaaggtcccaaa
cccaaaagggagaaaaaggagcctggtaccagggtgagaaaaacacctacatcatctggt
aaatccactgcaaagaaagtgaagaaacggaatccttggtcagatgatgaatccaagtca
gaaagtgacttggaagaaacagagcctgtggttattcccagagattctttgcttaggaga
gcagctgctgaaaggcctaagtacacgtttgacttctcagaagaggaggatgatgatgct
gatgatgatgaggacaataatgatttagaggaattgaaagtgaaagcatctcccataaca
aatgatggggaagatgaatttgttccttcagatggcctagataaagatgaatatacattt
tcacctggcaaatcgaaagctactccagaaaaatcttcacatgacaaaaaaggtcaagat
tttgggaatctcttctcatttccttcatactctcagaagtcagaagatgattcagctaaa
tttgacagtaatgaagaagattctgcctctgttttttcaccatcgtttggtctgaaacaa
acagataaagttccaagtaaaacagtagctgctaaaaagggaaaaccatcttcagataca
actgctaagcccaagagaacccctaaacagaagaaagtagagactataaactctgactca
gattcagaattcggcattccaaagaagagtacacccccaaaaggtaaaggccgaggagca
aagaaaaggaaagcatctggctctgaaaatgaaggtgattataaccctggcaggaaaaca
tccaaaacaccaagcaagaaaatgaagaaaacctcttttgatcaggattcagatgtggac
atcttcccatcagatttcacttctgaagcaccttctctgccacggagcggtcgggctagg
aaagaagtaaaatattttgcagagtccgatgatgaagaagatgttgattttgcaatgttt
aattaa
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integrated database retrieval system
