KEGG   Prionailurus bengalensis (leopard cat): 122493437
Entry
122493437         CDS       T07574                                 
Symbol
CAMK2A
Name
(RefSeq) calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1
  KO
K04515  calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
Organism
pbg  Prionailurus bengalensis (leopard cat)
Pathway
pbg04012  ErbB signaling pathway
pbg04020  Calcium signaling pathway
pbg04024  cAMP signaling pathway
pbg04066  HIF-1 signaling pathway
pbg04114  Oocyte meiosis
pbg04148  Efferocytosis
pbg04217  Necroptosis
pbg04261  Adrenergic signaling in cardiomyocytes
pbg04310  Wnt signaling pathway
pbg04360  Axon guidance
pbg04713  Circadian entrainment
pbg04720  Long-term potentiation
pbg04722  Neurotrophin signaling pathway
pbg04725  Cholinergic synapse
pbg04728  Dopaminergic synapse
pbg04740  Olfactory transduction
pbg04750  Inflammatory mediator regulation of TRP channels
pbg04911  Insulin secretion
pbg04912  GnRH signaling pathway
pbg04916  Melanogenesis
pbg04921  Oxytocin signaling pathway
pbg04922  Glucagon signaling pathway
pbg04925  Aldosterone synthesis and secretion
pbg04934  Cushing syndrome
pbg04971  Gastric acid secretion
pbg05012  Parkinson disease
pbg05022  Pathways of neurodegeneration - multiple diseases
pbg05031  Amphetamine addiction
pbg05152  Tuberculosis
pbg05200  Pathways in cancer
pbg05205  Proteoglycans in cancer
pbg05214  Glioma
pbg05415  Diabetic cardiomyopathy
pbg05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pbg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    122493437 (CAMK2A)
   04310 Wnt signaling pathway
    122493437 (CAMK2A)
   04066 HIF-1 signaling pathway
    122493437 (CAMK2A)
   04020 Calcium signaling pathway
    122493437 (CAMK2A)
   04024 cAMP signaling pathway
    122493437 (CAMK2A)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    122493437 (CAMK2A)
  09143 Cell growth and death
   04114 Oocyte meiosis
    122493437 (CAMK2A)
   04217 Necroptosis
    122493437 (CAMK2A)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    122493437 (CAMK2A)
   04922 Glucagon signaling pathway
    122493437 (CAMK2A)
   04912 GnRH signaling pathway
    122493437 (CAMK2A)
   04921 Oxytocin signaling pathway
    122493437 (CAMK2A)
   04916 Melanogenesis
    122493437 (CAMK2A)
   04925 Aldosterone synthesis and secretion
    122493437 (CAMK2A)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    122493437 (CAMK2A)
  09154 Digestive system
   04971 Gastric acid secretion
    122493437 (CAMK2A)
  09156 Nervous system
   04725 Cholinergic synapse
    122493437 (CAMK2A)
   04728 Dopaminergic synapse
    122493437 (CAMK2A)
   04720 Long-term potentiation
    122493437 (CAMK2A)
   04722 Neurotrophin signaling pathway
    122493437 (CAMK2A)
  09157 Sensory system
   04740 Olfactory transduction
    122493437 (CAMK2A)
   04750 Inflammatory mediator regulation of TRP channels
    122493437 (CAMK2A)
  09158 Development and regeneration
   04360 Axon guidance
    122493437 (CAMK2A)
  09159 Environmental adaptation
   04713 Circadian entrainment
    122493437 (CAMK2A)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122493437 (CAMK2A)
   05205 Proteoglycans in cancer
    122493437 (CAMK2A)
  09162 Cancer: specific types
   05214 Glioma
    122493437 (CAMK2A)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    122493437 (CAMK2A)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    122493437 (CAMK2A)
   05022 Pathways of neurodegeneration - multiple diseases
    122493437 (CAMK2A)
  09165 Substance dependence
   05031 Amphetamine addiction
    122493437 (CAMK2A)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    122493437 (CAMK2A)
   05415 Diabetic cardiomyopathy
    122493437 (CAMK2A)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    122493437 (CAMK2A)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pbg01001]
    122493437 (CAMK2A)
Enzymes [BR:pbg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.17  Ca2+/calmodulin-dependent protein kinase
     122493437 (CAMK2A)
Protein kinases [BR:pbg01001]
 Serine/threonine kinases: CAMK group
  CAMK2 family
   122493437 (CAMK2A)
SSDB
Motif
Pfam: Pkinase CaMKII_AD PK_Tyr_Ser-Thr DUF4440 SnoaL_3 SnoaL_2 Kdo SnoaL_4
Other DBs
NCBI-GeneID: 122493437
NCBI-ProteinID: XP_043453940
LinkDB
Position
A1:197571406..197633944
AA seq 489 aa
MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE
ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL
EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL
SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV
TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK
GAILTTMLATRNFSGGKSGGNKKNDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQE
IIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKP
VHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHR
SGAPSVLPH
NT seq 1470 nt   +upstreamnt  +downstreamnt
atggccaccatcacctgcacccgcttcacggaagagtaccagctcttcgaggaactggga
aagggagccttctcggtggtgcgcaggtgtgtgaaggtgctggctggccaggagtatgct
gctaagatcatcaacaccaagaagctgtcggccagagaccatcagaagctggagcgtgaa
gcccgcatctgccgcctgttgaagcaccccaacatcgtccggctccacgacagcatctct
gaggagggacaccattacctgatcttcgacctggttactggtggggagctgtttgaggac
atcgtggcccgggagtattacagtgaggctgatgccagtcactgtatccagcagatcctg
gaggccgtgctgcactgccaccagatgggtgtggtgcaccgggacctgaagccggagaat
ctgctattggcttccaagctcaagggcgccgcggtgaagctggcggactttggcctggcc
atagaggtggaaggggagcagcaggcatggttcgggttcgcagggacgcctggatacctc
tccccggaagtgctgcggaaggacccgtatgggaagcctgtggacctgtgggcctgtggg
gtcattctgtacatcctgctggttgggtatccgccattctgggatgaggaccagcaccgc
ctgtatcagcaaatcaaagccggcgcctatgatttcccgtcaccagaatgggacactgtc
accccggaagccaaggatctgatcaataagatgctgaccatcaacccatccaaacgcatc
acggctgccgaggccctcaagcacccttggatctcgcatcggtccactgtggcctcctgc
atgcacagacaggagaccgtggactgcctgaagaagttcaacgccaggagaaaactgaag
ggagccatccttaccacaatgctggctaccaggaacttctctggagggaagagcggagga
aacaagaagaatgatggtgtgaagaaaagaaagtccagttccagcgttcagttaatggaa
tcttcagagagtaccaataccaccattgaggatgaagacaccaaagtgcggaaacaggag
attataaaagtgacagagcagctgatcgaagccataagcaatggagattttgagtcctac
acgaagatgtgtgaccctgggatgacagccttcgaacctgaggccctggggaacctggtc
gagggcctggacttccatcgattctattttgaaaacttgtggtctcggaacagcaagccc
gtgcacaccaccatcctgaacccccacatccatctgatgggtgacgagtcggcctgcatc
gcctacatccgcatcacgcagtacctggatgcgggtggcatcccccgcacggcccagtcg
gaggagacccgtgtctggcaccgccgggatggcaaatggcagatcgtccacttccacaga
tctggggcgccctccgtcctgccccattga

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