KEGG   Prionailurus bengalensis (leopard cat): 122493457
Entry
122493457         CDS       T07574                                 
Symbol
PPP3CB
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
pbg  Prionailurus bengalensis (leopard cat)
Pathway
pbg04010  MAPK signaling pathway
pbg04020  Calcium signaling pathway
pbg04022  cGMP-PKG signaling pathway
pbg04114  Oocyte meiosis
pbg04218  Cellular senescence
pbg04310  Wnt signaling pathway
pbg04360  Axon guidance
pbg04370  VEGF signaling pathway
pbg04380  Osteoclast differentiation
pbg04625  C-type lectin receptor signaling pathway
pbg04650  Natural killer cell mediated cytotoxicity
pbg04658  Th1 and Th2 cell differentiation
pbg04659  Th17 cell differentiation
pbg04660  T cell receptor signaling pathway
pbg04662  B cell receptor signaling pathway
pbg04720  Long-term potentiation
pbg04724  Glutamatergic synapse
pbg04728  Dopaminergic synapse
pbg04921  Oxytocin signaling pathway
pbg04922  Glucagon signaling pathway
pbg04924  Renin secretion
pbg05010  Alzheimer disease
pbg05014  Amyotrophic lateral sclerosis
pbg05020  Prion disease
pbg05022  Pathways of neurodegeneration - multiple diseases
pbg05031  Amphetamine addiction
pbg05152  Tuberculosis
pbg05163  Human cytomegalovirus infection
pbg05166  Human T-cell leukemia virus 1 infection
pbg05167  Kaposi sarcoma-associated herpesvirus infection
pbg05170  Human immunodeficiency virus 1 infection
pbg05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pbg05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pbg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    122493457 (PPP3CB)
   04310 Wnt signaling pathway
    122493457 (PPP3CB)
   04370 VEGF signaling pathway
    122493457 (PPP3CB)
   04020 Calcium signaling pathway
    122493457 (PPP3CB)
   04022 cGMP-PKG signaling pathway
    122493457 (PPP3CB)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    122493457 (PPP3CB)
   04218 Cellular senescence
    122493457 (PPP3CB)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    122493457 (PPP3CB)
   04650 Natural killer cell mediated cytotoxicity
    122493457 (PPP3CB)
   04660 T cell receptor signaling pathway
    122493457 (PPP3CB)
   04658 Th1 and Th2 cell differentiation
    122493457 (PPP3CB)
   04659 Th17 cell differentiation
    122493457 (PPP3CB)
   04662 B cell receptor signaling pathway
    122493457 (PPP3CB)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    122493457 (PPP3CB)
   04921 Oxytocin signaling pathway
    122493457 (PPP3CB)
   04924 Renin secretion
    122493457 (PPP3CB)
  09156 Nervous system
   04724 Glutamatergic synapse
    122493457 (PPP3CB)
   04728 Dopaminergic synapse
    122493457 (PPP3CB)
   04720 Long-term potentiation
    122493457 (PPP3CB)
  09158 Development and regeneration
   04360 Axon guidance
    122493457 (PPP3CB)
   04380 Osteoclast differentiation
    122493457 (PPP3CB)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    122493457 (PPP3CB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    122493457 (PPP3CB)
   05170 Human immunodeficiency virus 1 infection
    122493457 (PPP3CB)
   05163 Human cytomegalovirus infection
    122493457 (PPP3CB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    122493457 (PPP3CB)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    122493457 (PPP3CB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    122493457 (PPP3CB)
   05014 Amyotrophic lateral sclerosis
    122493457 (PPP3CB)
   05020 Prion disease
    122493457 (PPP3CB)
   05022 Pathways of neurodegeneration - multiple diseases
    122493457 (PPP3CB)
  09165 Substance dependence
   05031 Amphetamine addiction
    122493457 (PPP3CB)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    122493457 (PPP3CB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:pbg01009]
    122493457 (PPP3CB)
Enzymes [BR:pbg01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     122493457 (PPP3CB)
Protein phosphatases and associated proteins [BR:pbg01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     122493457 (PPP3CB)
SSDB
Motif
Pfam: Metallophos DUF5378
Other DBs
NCBI-GeneID: 122493457
NCBI-ProteinID: XP_043453993
LinkDB
Position
D2:complement(33666375..33725308)
AA seq 534 aa
MAAPEPARAAPPPPPPPPPPPGADRVVKAVPFPPTHRLTSEEVFDMDGIPRVDVLKNHLV
KEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANT
RYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYS
ERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLL
WSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMY
RKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFT
WSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDERLIYGNKKVGSAAARKEIIRNKIR
AIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGF
SPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHSAQ
NT seq 1605 nt   +upstreamnt  +downstreamnt
atggccgccccggagccggcccgggctgcaccgcccccacccccgcccccgccgccccct
cccggggctgaccgcgtcgtcaaagctgtaccttttcccccaacacatcgcttgacatct
gaagaagtatttgatatggatgggatacccagggttgatgttctgaagaatcacttagta
aaagaaggtcgggtagatgaagaaattgcacttagaattatcaatgagggtgctgccatc
cttcggagagagaaaaccatgatagaagtagaggctccaattacagtgtgtggtgacatc
catggccaattttttgatctgatgaaactttttgaagtaggaggatcacctgctaataca
cgatacctttttcttggtgattatgtggacagaggttattttagtatagagtgtgtctta
tatttatgggtcctgaagattctttacccaagcacattatttcttctgagaggcaatcat
gaatgcagacaccttactgaatattttacctttaagcaggaatgtaaaattaaatattca
gaaagagtctatgaagcttgtatggaagcttttgatagcctgcctcttgctgcactttta
aatcaacaatttctttgtgttcatggtggactttcaccagaaatacacacactggatgat
attaggagattagatagattcaaagagccacctgcatttggaccaatgtgtgacttgcta
tggtccgatccttctgaagattttggaaatgaaaaatcacaggaacattttagtcacaat
acagttcgaggatgttcttatttttataactatccagcagtgtgtgaatttttgcaaaac
aataatttgttatcgattattagagctcatgaagctcaagatgcaggctatagaatgtac
agaaaaagtcaaactacagggttcccttcattaataacaattttttcggcacctaattac
ttagatgtctacaataataaagctgctgtattaaagtatgaaaataatgtgatgaatatt
cgacaatttaactgttctccacatccttactggttgcccaattttatggatgtcttcaca
tggtctttaccatttgttggagaaaaagtgacagaaatgttggtaaatgttctgagtatt
tgctctgatgatgaactgatgactgaaggtgaagaccaatttgatgaacggctcatatat
ggcaataaaaaagtaggttcagctgcagcccggaaagaaatcataagaaacaaaattcga
gcaattggcaagatggcaagggtcttctctgttctcagggaggagagtgaaagcgtgctg
acactcaagggcctgactcccacagggatgttgcctagtggagtgttggctggaggacga
cagaccctgcaaagtgccacagttgaggctattgaggctgaaaaagcaatacgaggattc
tctccaccacatagaatctgcagttttgaagaggcaaagggtttggataggatcaatgag
agaatgccaccccggaaagatgctgtacagcaagatggtttcaattctctgaacaccgca
catgccactgagaaccacgggactggcaaccatagtgcccagtga

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