Prionailurus bengalensis (leopard cat): 122494522
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Entry
122494522 CDS
T07574
Symbol
HSD17B2
Name
(RefSeq) 17-beta-hydroxysteroid dehydrogenase type 2 isoform X1
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg00140
Steroid hormone biosynthesis
pbg01100
Metabolic pathways
pbg04913
Ovarian steroidogenesis
Module
pbg_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
122494522 (HSD17B2)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
122494522 (HSD17B2)
Enzymes [BR:
pbg01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
122494522 (HSD17B2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
122494522 (HSD17B2)
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Motif
Pfam:
adh_short
adh_short_C2
KR
Oxidored_nitro
DUF1776
NmrA
Epimerase
Motif
Other DBs
NCBI-GeneID:
122494522
NCBI-ProteinID:
XP_043455693
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Position
E2:55873380..55966560
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AA seq
385 aa
AA seq
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MAGMPTQDSLPLPDLPDLSGCLRSHAHTHTHTHTRPSQKKNLTVTPPAPAGEEFFCELKV
LLFTVRIEFCQLLSTWLSLQRSRKRKKRVCVVGGDSGFGHALSKYLDELGFTVFVGVLNE
KGPGAEELRRTCSERVSVLQMDITNPQQIKDAHSKVVEKVQNRGLWAVVNNAGIIGLPAD
GELIPMTNYKQCMAVNFFGAVEVTKVFLPLLRKSKGRLVNISSMAGGVPLEKLAAYSSSK
AALTMFSAVMRQELSKWGVKVSVIQPGGFKTSIAGTSEMWNKLEQDILDNLTPEVLEDYG
QDYILEQRDYLKFISRCTNTDMSPVLMDIRHAVSAKSPFAFYSPGPMAYPMLCFVSFSPT
GIFDYFSKKLYHFRGSMPKALTKQA
NT seq
1158 nt
NT seq
+upstream
nt +downstream
nt
atggcaggaatgccaactcaggacagccttccccttccagatcttccagacctctctggt
tgcctgcgttcacacgcacacacacacacacacacacacacacgcccgagtcagaaaaag
aatttgacagtcacaccaccggctcctgccggcgaagagtttttctgtgaactaaaggtc
ttgttattcactgttcggattgaattctgtcaattattatccacctggttatctctccag
aggtcacggaaaagaaaaaaacgtgtgtgtgttgtgggtggtgattctggatttggccat
gccctgtccaaatatctggatgagcttggcttcacggtatttgtcggagttctgaatgaa
aagggaccaggagcagaggaactgcgaagaacctgctccgagcgcgtctccgtgctccag
atggacatcaccaacccgcagcagataaaagacgcccacagcaaagtggtggaaaaggtg
cagaacagaggactgtgggctgtggtcaacaatgctgggatcattggcttaccagcggac
ggggagctcattcccatgactaactacaaacaatgcatggccgtgaacttctttggggcc
gtggaggtcacaaaggtatttttgcctcttcttaggaaatccaaggggaggctggtgaac
atcagcagcatggcaggaggggtcccattggagaagctggcagcctatagctcatccaag
gcagctctaaccatgttttcagcagtcatgagacaagagctttccaaatggggagttaaa
gtctctgtcatccagcctggaggcttcaaaacaagtatcgcgggcacgagtgaaatgtgg
aacaagctggagcaggacatcctggacaaccttacccccgaagtgctagaggactatggg
caggactatatccttgagcaacgggattatctcaagttcatcagcaggtgtaccaacact
gatatgtcccctgtgctcatggacatccggcatgccgtgtctgctaagagcccctttgcc
ttttactcgccagggccgatggcttatccaatgctctgctttgtttcatttagtcctact
ggcatatttgattattttagcaaaaagttgtatcactttagagggagcatgcccaaggcg
ctaactaagcaggcctaa
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