Prionailurus bengalensis (leopard cat): 122497281
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Entry
122497281 CDS
T07574
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg00140
Steroid hormone biosynthesis
pbg01100
Metabolic pathways
pbg05215
Prostate cancer
Module
pbg_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
122497281 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
122497281 (SRD5A2)
Enzymes [BR:
pbg01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
122497281 (SRD5A2)
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Motif
Pfam:
Steroid_dh
DUF1295
DUF6832
Motif
Other DBs
NCBI-GeneID:
122497281
NCBI-ProteinID:
XP_043460138
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Position
A3:115081439..115124634
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AA seq
254 aa
AA seq
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MRVPCQQSPVLAGSAALAALGALVLYLAEPSGYGKYSERAMPAAARLPARAAWFLQELPS
FAVPAGILARQPRALFGPPATVLLGLFCGHYFYRTFVYSLRTRGRPFPVVFLVKGFIFCM
GNGLLQGYYLIYCAEYPADWYTDIRFSLGVFLFILGMGINIHSDCILRQLRKPGEVIYRI
PQGGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFSLCFLGLRAFHHHRFYLKMFE
DYPKSRKALIPFIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgcgggttccctgccagcagagcccggtgctggcgggcagcgctgccctggccgccctg
ggggcattggtcctgtacctggcggagccctccggctacgggaagtactcggagcgcgca
atgcccgctgctgctcgcctgccagcccgcgcagcctggttcctgcaggagttgccatcc
ttcgccgtgcctgcggggatcctcgcccggcagccgcgtgctctcttcggccctccggcc
accgtgcttctgggcctcttctgcggacattacttctacaggacatttgtttactcattg
cgtactagagggaggccttttccagttgtgttcctcgtcaaaggctttattttctgcatg
ggaaatggacttctccaaggctactatctgatttactgtgctgaataccctgctgattgg
tacacagacatacggtttagcctgggtgtcttcttatttattttgggaatggggatcaac
attcatagcgactgtatactgcgccagctcaggaagcctggagaagtcatctataggatt
ccacaaggtggcttgtttacctacgtttctggagccaatttccttggtgagatcattgaa
tggatcggctatgccctggccacgtggtcgctcccagcgcttgcatttgcctttttctca
ctttgtttccttgggctgcgagcttttcaccaccataggttctacctcaagatgtttgag
gactaccccaaatctcggaaagccctcattccattcatcttttaa
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