Python bivittatus (Burmese python): 103048178 Help Entry 103048178         CDS       T03091                                  Symbol UBR4 Name (RefSeq) E3 ubiquitin-protein ligase UBR4   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism pbi  Python bivittatus (Burmese python) Brite KEGG Orthology (KO) [BR:pbi00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:pbi04121]     103048178 (UBR4) Enzymes [BR:pbi01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      103048178 (UBR4) Ubiquitin system [BR:pbi04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     103048178 (UBR4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  E3_UBR4_N E3_UbLigase_R4 UBR4 zf-UBR Motif Other DBs NCBI-GeneID:  103048178 NCBI-ProteinID:  XP_025027640 UniProt:  A0A9F5IM08 LinkDB All DBs Position Unknown AA seq 5037 aa AA seqDB search MSVDKDNTCISHGSFLYCSESEILHHDKQYEPFYSSFVALATHYITTVCGVVPRNQLQSV AAACKVLIEFSLLRLENPDEACAVSQKHLILLIKGLCTGCSRLDRTEIITFTAMMKSAKL PQTVKTLSDVEDQKELASPVRPELRQKEVQMNFLNQLTSVFNPKMALSPMTLQAQGEGEG EEQAPTDQASAAKTKSIFVAQNVASLQELGGSEKLLRVCLNLPYFLRYINRFQDAVSANS FFIMPATVADATAVRNGFHSLVIDVTMALDTLSLPVLEPLTPARLQDVTVLALSCLYAGV SVATCMAILHVGTTQQVRTGSTSSKEEDYENDAAIIVQKCLEIYDMIGQAISSSRRAGGE HYQNFQLLGAWCLLNSLFLILNLSPTTLADKGKEKDPLAALRVRDIVVRSKEGVGSPKLG PSKGHQGFGILSVVLANHAIKLLTLLFQDLHVEALHKGWETDGPPAALNIMAQSTSIQRI QRLIESVPLANLLLTLLSTAYRKVGAWRGLITWASSPRVKSPNKPSAGENGNILASRKDP ELFLNLASNILNFLTSSMLDSKNNFIRNYLSVSLTEQHMATLASIIKEVDKDGLKGTSEE DEFAAALYHFNHSLVTSDLQSPTLQNILLQQLGVSPFSEGPWPLYIHPQSLSVLSRFLLI WQHKASTQTDPDVPECLNVWERFVGTLKQNALQGILPGDAEDLNVEHLQLLLLIFHSFSE KGRRSILTLCVQTILEVAANLDSQLRCVPLLLARLLLVFDYLLHQYSKAPVYLFEQVQYN LLTPPIVWPSGNQEGSRQAFSPLYHGFKEVEENWAKHCPSDAAPQPRFYCILSPEASEDD LNRLDSTVCEVLFSKAMKYDELYSALASLLAAGSQFDTLRRKETKNVTALEACALQYYFL ILWRILGILPPSKNYMNQLAMNSPEMRECDILHTLRWSSRLHIPSYVSWIKDHLIKQGMK PEHASSLVELTAAKCSSMKYDVEIAEEYFARQISSFCGIDCTTILQLHEIPSLQSIYTLD AAISKVQVSLDEHFSKLAAETDPHKSSEITKNLLPAALQLIDTYATFTRSYLLQSLSEDS SAENKPTEEKLQGYAAVLAIGSSRCKSNTLGPALIQNLPSAVQSLCESWNSIHTNEFPNI GSWRNAFANDTIPAESYISAVQAAHLGTLCSQSLPLAASLKHTLLSLVRLTGDLVVWSDD LNPPQVIRTLLPLLLETSTESVAEMSSNSLERILGPAESDEFLSRVYEKLIMGCYNILAN HSDPNSGLDEAILEECLQHLEKQLESSQARKAMEEFFSDSGELVQIMMATANENLSAKFC NRVLKFFTKLFQLTEKSPNPSLLRLCGSLAQLACVEPVRLHAWLTRMTTSPPKESDQLEV VQENRQLLQLLTTYIVRENSQVGEGACTVLLSTLIPMATEMLANGDGTGFPELMVVMATL ASAGQGAGHLQLHSAAVDWLGRCKKYLSQKNVIEKMNASVMHGKHVTILECTCHIVSYLA DVTNALSQSSSQGTSHLSVDGEERAIEVDSDWVEELAVEEEDSQAEDSDEDSLCNKLCTF TITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAKEDGSC LALVKRTPSSGISSTMKESAFQSEPRVSESVRHSSTSPTDKSKSSASDGRGADEDKPKKS SLCRNVEGCREQLQAQANFSFASLVLDLLSFLMEAIQINFQQASAMGSSSRAQQALNQLH TLDKTVEMTDQLMVPTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPH GRRQHLAVSHEKGKITVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDY LAVCGLKDCHVLTFSSSGSVSDHLVLHPQLATGNFIIKAVWLPGSQTELAIVTADFVKIY DLSVDALSPTFYFLLPSSKIRDITFLFNEEGKNIVVIMSSAGYIYLQLMEEASSAQHGPF YVTNVLEVAHEDLKDSNGQVAGGGVSVYYSHVLQMLFFSYCQGKSFAATISRATLEVLHL FPINIKSSNGSSKTSPALCQWSEVMNHPGLVCCVQQTTGVPLVMMVKPDTFLIQEIKTLP AKAKIQDMVAIRHTACNEQQRTTMILLCEDGSLRIYMANVENTSHWLQPALQPSSVISIM KPVRKRKAAAIPTRTSTQVNFPIDFFEHNQQLTDVEFGGNDLLQVYNAQQIKHRLNSTGM YVANTKPGGFTIEVTNNNSTMVMTGMRVQIGTQAIERAPSYLEVFGRTMQLNLSRPRWFD FPFTREEALQADKKLTIFIGASVDPAGVTMLDAVKIYGKTKEQFGWPDEPPEDFPSASVS SVCPPNLNQGNGAGDTESATPAAAGGTVLERLVVSSLEALESWFAVGPVNEKEKSKAATQ ELATMLLSTPTPSSVQQQTKSLLASLHTSRSAYHSHKDQALLSKAVQYLTTSSKEGKDLD PEVFQRLVITARSIAIMRPNNLVHFTESRFPCLETEGGEEGQEATKTAEGEGCTFITQLV NHFWKLHASKPKNAFLAPACLPGLTHVEATVNALIDILHGYCICELDCINAASKIYMQML LCPDPAVSFSCKQALIRVLRPRNKRRHVTLPSSPRSNTPMGDKDDYDDDDADDKLQASSL PSGEDIRQESQEQNEVDHGDFEMVSESMVLETADNVNNGNPSPLEALLAGAEGFPPMLDI PPDADDETMVELAIALSLQQDQQGSSSSALGLQSLGLSGQAPSSSSLDAGTLSDTTASAP ASDDEGSTAATDGSTLRTSPADHGGSVGSESGGSAVDSVAGEHSVSGRSSAYGDTAAEGH PAGPGSVSSSTGAISTTTGQQEGEGSEGEGEGEGDVHASNRLHMVRLMLLERLLQTLPQL RNVGGVRAIPYMQVILMLTTDLDGDEEKDKGALDNLLAQLIAELCMEKKDVSKKNERSAL NEVHLVIMRLLSVFMSRTKSGSKSSICESSSLISSATAAALLSSGAVDYCLHVLKSLLDY WKSQQNDEEPVTASQLLKPHTTSSPPDMSPFFLRQYVKGHAADVFEAYTQLLTEMVLRLP YQIKKIADTNSRIPPPVFDHSWFYFLSEYLMIQQTPYVRRQVRKLLLFICGSKEKYRQLR DLHTLDSHVRGIKKLLEEQGIFLRASVVTASSGSALQYDTLISLMEHLKACAEIATQRTV NWQKFCIKDDSVLYFLLQVSFLVDEGVSPVLLQLLSCALCGSKVLSGTASAGSSGTSASA PGGSGAGQPTGQSKSSTKKSKKEDKEKEREGEGSSGSQEDQLCTALVNQLNKFADKETLI QFLRCFLLESNSSSVRWQAHCLTLHIYRNSNKSQQELLLDLMWSIWPELPAYGRKAAQFV DLLGYFSLKTQQTEKKFKEYSQKAVEILRMQNHILTNHPNSNIYNTLSGLVEFDGYYLES DPCLVCNNPEVPFCYIKLSSIKVDTRYTTTQQVVKLIGSHTISKVTVKIGDLKRTKMVRT INLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKIDLPLPIVASNLMIEFADFYE NYQASTETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSINYDEKDPFLCNACGFCKYA RFDFMLFAKPCCAVDPIENEEDRKKAVTNINTLLDKADRVYHQLMGHRPQLENLLCKVNE AAPEKPQDDSGGSGGISSTSASVNRYILQLAQEYCGDCKNSFDELSKIIQKVFASRKELL EYDLQQREAASKSSRSAVQPTFTASQYRALSVLGCGHTSSTKCYGCASAVTEHCITLLRA LATNAAIRHILVSQGLIRELFDYNLRRGAATMREDVRQLMCLLTRDNPEATQQMNDLIIS KVSAALKGHWANPDLASSLQYEMLLLTDSISKEDSCWELRLRCALSLFLMAVNIKTPVVV ENITLMCLRILQKLIKPPAPTSKKNKVPALLAHLEANGKSPGRTELRHLYLTEKYAWKWK QFMSKRGKRTCPLDLKLGHNNWLRQVLFTPATQAARQAACTIVEALATIPSRKQQVLDLL TSYLDELSVAGECAAEYLALYQKLIKPARWKVYLAARGVLPYVGNLITKEIARLLALEEA TLSTDLQQGYALKSITGLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLVVQRTKLIDE TQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYSLDDYRTPVFIFERLCSIIYPEENEV TEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLVALLEDDSGM ELLVNNKIISLDLPVAEVYKKVWCPTNEGEPMRIIYRMRGLLGDATEEFIESLDSTTDEE EDEEEVYKMAGVMAQCGGLGCMLNRLTGIKDFKQGRHLLTVLLKLFSYCVKVKVNRQQLV KLEMNTLNVMLGTLNLALVAEQESKDSGGAAVAEQVLSIMEIILDESNAEPLSEDKGNLL LTGDKDQLVMLLDQINSTFVRSNPSVLQGLLRIIPYLSFGETEKMEILVDRFKPYCSFDK YDEEHSGDDKVFLDCFCKIAAGIKNNSNGHLLKDLILQRGITQSALDYMKKHIPSAKNLD ADVWKKFLSRPALPFILRXXXXXXXXXPPYQALIGTDSISNLHKLEQVSSDEGIGTLAEN LLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQ MEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEFENKPRKQQGYSTVSHFNIV HYDCHLAAVRLARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQEC TGQREPTYQLNVHDTKLLFLRFATEQSFSVDTGGGGRESNIHLIPYIIHTVLYVLNTTRA TSREEKNLQSFLEQPKEKWVESAFEVDGPHYYTVLALHILPPERWKAVRIDILKRLLVIS HARVVSPGGASKLTDKAVKDYAAYRSSLLFWALVDLIYNMFRKVPTSNTEGGWSYSLAEY IRQNDMPIYEAADRALKSFQEEFMPAETFSEFLDVAGLLSEICDPDGFLKDLFNSLP NT seq 15114 nt NT seq  +upstreamnt  +downstreamnt atgtcggtcgacaaggataacacttgtatttctcatggttcttttctctactgcagtgaa tctgaaatcctgcaccacgacaagcaatatgagcctttctactcatcttttgttgccctc gcaacccactacatcaccacagtgtgcggagtggtacctcggaatcagctgcaatctgta gcggctgcctgcaaagtactgatcgaattctctctgttgcgacttgaaaacccagatgaa gcatgtgctgtctcacagaaacacctgatcctgctgatcaaggggttgtgcaccggctgc agccgcctggacaggacggagatcatcactttcacagcgatgatgaagtcagccaagctc ccccagacagtgaagactctctcggacgtggaggatcagaaagagctggcttctcccgtc aggcccgaactgcgacagaaggaggtgcagatgaactttctcaatcagctgacctctgtc ttcaatcccaaaatggccctgtctccaatgacactgcaggctcagggggaaggggaaggc gaagagcaggcccccacggaccaagcctctgcggccaaaaccaagagcatatttgttgcc cagaacgtggccagcttgcaagaacttggtggttctgaaaaactgctgcgcgtctgcttg aatctcccatacttcctgcgctacattaaccggttccaagacgccgtgtcggccaattcc tttttcatcatgccagctaccgtagctgatgccacagccgtccgcaatgggttccattcc ctggtgattgatgtgaccatggccctggacacgctctcccttccggtcctggagcctctg actcccgcccgcctgcaggacgtcaccgttctggcactcagctgcctctacgcaggggtg agcgtggccacctgcatggcaatcctgcacgtgggcaccacccagcaagtccgcacgggt tctacaagctccaaagaagaagactatgaaaacgacgcagccatcattgtacagaaatgc cttgaaatctatgacatgatcggccaagcaatcagcagttcccgccgcgcaggcggggag cactaccagaacttccagctgctcggggcctggtgtctgctgaacagcttattcctcatc ttgaacctcagcccgaccaccctggccgacaaggggaaagagaaagacccactggcagcc ctccgggtccgggatatcgttgttcggtccaaagagggtgtggggtctcccaaacttgga cccagcaaagggcatcaggggttcggcatcctctcggttgttctggccaatcacgccatc aagctccttaccctgctctttcaagacctccacgtagaggcgcttcacaagggctgggag acggatggccccccagctgccctgaacatcatggcccagagtacttcaatccagagaatt cagcgcttgatcgagtcggtgcctcttgccaatctgctgctgaccctgctctccacggct tacaggaaggtgggtgcttggagagggcttatcacgtgggcaagctccccccgggtgaaa agccccaacaagccatcggcaggagaaaacgggaacatcctagccagtcgcaaagacccg gaactgttcttaaatctggcctcgaacatcctcaacttcttgacttcctccatgctggac tcgaagaataatttcattcgcaactacctgagcgtgtctctgacggagcagcacatggcc accttagctagcatcatcaaagaagtggacaaggacgggctcaaagggacctccgaagag gacgagtttgctgctgcgctgtatcacttcaaccactctttggtgacctctgacctccag tctcctaccttgcagaatattctcctgcagcagctgggagtgtctcctttctccgaaggg ccctggcctctctacatccacccccagagcttgtcggtgctctctcgttttctcctgatc tggcagcataaagccagcacccagacggacccggatgtgccagaatgtctgaatgtgtgg gagaggtttgtgggcactttgaagcagaacgccctgcaggggattcttcctggcgacgcg gaggatctcaatgtggagcacctccagctcctgttgctgatcttccacagtttctctgag aaaggccggcggtccatcctgaccctctgcgtccagacaatcctagaagttgcagccaat ttggactctcagctccgatgcgtccctctcctgctggcccggcttctcttggtctttgac tacctgcttcaccaatactcgaaggctcccgtgtatttatttgagcaggtgcagtacaac ctcttgactcctcccatcgtttggcccagcgggaaccaggagggcagccgacaagccttt tccccgctttatcacggtttcaaggaagtggaagaaaactgggccaagcactgtccctct gatgctgccccccagcctcgcttctactgcattctctccccggaagcatctgaagatgac ttgaaccgcctcgatagcacggtgtgcgaggtcttgttctccaaggccatgaagtacgac gagctctattcggccctcgcctcgctgctggctgccggctcccagtttgacaccctccgc cgaaaggaaaccaaaaacgtcacggcgctggaggcctgcgcgcttcagtactacttcttg attctctggcggatccttgggatccttcccccttccaagaactacatgaaccagctggcg atgaacagcccagagatgcgcgagtgcgacattctccacacgctgcgctggtcctctcgc ctccacatcccctcctacgtcagctggatcaaggatcacctcatcaaacaggggatgaaa cctgagcacgcatcttcccttgtcgagctgactgctgccaaatgcagttccatgaagtac gatgtggaaatcgccgaggaatattttgcaaggcagatctcctctttctgcgggatcgat tgcaccacgatccttcagctgcatgagattcccagcttgcagtcgatctacaccctcgac gctgccatttcaaaagtccaggtctccctcgacgagcacttctccaagctggctgccgaa accgacccccacaaatcgtcagagatcacgaagaacctgttgccagccgccttgcagctg atagatacctacgccaccttcaccaggtcttacctcctgcagagtctttccgaggacagc tctgccgagaacaaaccgaccgaagagaagctgcaggggtatgctgccgtcctggcgatc ggctccagtcgctgcaaatccaacactttggggcctgctcttatccagaatttgccatca gctgtccagtcactgtgtgagtcctggaacagcattcataccaacgaattccccaacatt ggctcttggcgcaatgccttcgccaacgacacaattccggccgagagctacatcagtgcc gtgcaggccgcccacctgggcaccctctgcagtcagagccttcctttggcggcctcgctg aagcacaccctcctctccttggtcaggctcaccggggatctcgtggtctggtccgatgac ctgaacccgccccaggtgatccgcacgctgctgcctctcctgctggagaccagcaccgag agcgtggcggagatgagcagcaactccctcgagaggatcctgggcccagcggagtcggac gagttcctgtcacgggtctacgagaagctgattatgggctgctataacattctggccaac cactcggacccaaacagtggccttgatgaagccatcttggaagaatgtctgcaacatctg gagaaacagctggagagcagtcaagcccgaaaagccatggaggagtttttttctgacagt ggcgaactggtccagatcatgatggcaacagccaacgagaacctctctgccaagttctgc aaccgcgttctgaaattcttcaccaagctcttccagctaaccgagaagagtccaaacccc agccttctgcgcttgtgtggctccttggcccagctggcttgcgttgagcctgtgcgcctc cacgcgtggctgacacggatgaccacctctccccccaaagagtctgaccagctggaggtg gtgcaggagaaccggcagttgctgcagctgctgacgacctacatcgtgcgggagaacagt caagtcggcgagggagcctgcaccgtccttctgagtacgctgatccccatggctacggag atgctggcaaacggagatggaacaggctttccagagctcatggtggtcatggctacgctg gccagtgccgggcaaggggccggccacctccagctgcacagtgctgcggtggactggctg gggcgatgcaagaagtatctgtcccagaagaacgtgattgagaaaatgaacgccagcgtg atgcacggaaagcacgtgaccatcctggagtgcacgtgccacatcgtctcctacctggcc gatgtcaccaacgccctgagccaaagcagcagccagggcaccagccacctctcggtggac ggcgaagagcgggctatcgaagtggactctgactgggtggaagagctggccgtggaggag gaggactcacaggccgaagactcagatgaagactccctctgcaacaagctttgcacgttt accatcacgcagaaggaattcatgaaccagcactggtatcactgccacacctgtaagatg gtggatggtgtcggcgtttgtaccgtctgtgccaaggtttgccacaaggaccacgagatt tcgtatgctaaatacggatccttcttctgcgactgtggagcgaaggaggacggcagctgc ctggccctggtgaagaggacccccagcagcggcatcagctccaccatgaaggagtcagcc ttccaaagcgagcctcgtgtttcggagagcgtccggcattccagcacctcgcccactgac aagtccaagtcctcagccagtgatggccgaggggctgacgaggacaagcccaagaagagc agcctctgcagaaacgtggaaggttgccgggagcagttgcaggcccaggccaacttctcc ttcgcctctttggtccttgacctgctcagcttcctcatggaagccatccagatcaacttc cagcaggcctcggcgatgggcagcagcagccgggcccagcaggccctgaaccagttacac accctggacaagacagtggaaatgaccgaccagctcatggtgccgacgctgggctcccag gaaggcgcttttgagaacgtccggatgaactacagtggggaccaaggccagaccatccgg cagctgatcagcgcccacgtcctgagacgggtggccatgtgtgtgctttcctcgccccac ggacggcgccagcacctggctgtcagccacgagaaggggaagatcacggtgctccagctc tcggcgttgctcaagcaagccgactccagcaagcggaagctgactctaactcgcctcgcc tctgcccccgttcccttcacggtgctgagccttacagggaacccctgcaaggaggactac ctggccgtatgcgggctgaaggactgtcacgtcctcacgttcagcagttccgggtctgtc tcagatcacttggtgctgcaccctcagcttgccacgggcaacttcatcatcaaagcggtc tggcttccagggtcacagacggaactggccatcgtcacggctgactttgtcaagatctac gacctctcggtggatgccctgagccccaccttctacttcctgctgccaagctccaagatc agggacatcacgtttctctttaacgaagagggcaagaacatcgtggtcatcatgtcctcg gctggttacatctacctgcagctcatggaggaggccagcagcgcccagcacggccctttc tacgtcaccaacgtcctggaagttgcacacgaggacctgaaggacagcaacggccaagtg gccgggggcggcgtgtccgtctactactcccatgtcctgcagatgcttttcttcagctac tgccaggggaaatcctttgctgccacgatcagccgagccaccttggaggtgctgcatctc tttcccatcaacatcaagagctccaacgggagcagcaagacctccccggccctctgccag tggtcggaagtcatgaaccaccctggcctggtgtgctgcgtgcaacagacgacgggcgtt cctctcgtgatgatggtgaagcctgacaccttcctcattcaggagattaaaactttgcca gctaaagccaagatccaagacatggtagccatccggcacacggcctgcaacgagcagcag cggaccaccatgatcctgctgtgcgaggacggcagcctgcgcatctacatggccaacgtt gagaacacgtcccactggctccagcccgccctccagcccagcagcgtcatcagcattatg aagcctgtccgcaaacgcaaagcggcagccatccccacgcgcacctccacccaagtgaac ttccccattgacttcttcgagcacaaccagcagctgacggacgtggagtttgggggcaac gacctcctgcaggtctacaacgcccagcagatcaagcaccgtctcaactccaccggcatg tacgtggccaacaccaagcccggggggttcaccatcgaggtgacgaacaacaacagcacc atggtgatgacgggcatgcgggtccagatcggaacacaagccatcgagagagccccctcc tacctggaagtctttggccggaccatgcagctcaacctcagccgccctcggtggtttgac ttcccctttacgcgagaggaagccctgcaggccgataagaagctgaccattttcatcggg gcatctgtggatcccgccggggtcaccatgctggacgccgtcaagatctacggcaagacc aaggagcagtttggctggccggacgaacccccggaagacttcccgtcagcatccgtgagc agcgtctgccccccaaatctgaatcaggggaacggtgccggagacacggagtcagccacc ccagcagccgctggcggcaccgtcttggagaggctagtagtgagttctttggaagcgctg gaaagttggtttgctgtcggaccagtcaacgagaaggaaaagagcaaggctgccacgcag gagctagccaccatgcttctgtccacgccgaccccttccagtgtccagcagcagaccaag agcctcctggccagcctccacaccagccgctcagcttaccacagccacaaggatcaggcc ttgttgagcaaagccgtccagtatctcaccacctccagcaaagaagggaaagacctcgac ccggaggtctttcagaggctggtcatcacggcccgctccatcgccatcatgagaccgaat aacctggtccatttcacagagtcaaggtttccgtgtctggaaacagaaggcggtgaagaa ggacaggaggctacgaagactgcggaaggggaagggtgcacttttattacccagctggtc aaccatttctggaaacttcacgcctcaaaacccaagaatgccttccttgcgcctgcttgc ttgccaggcctgacccacgttgaggccactgtcaacgccctcatagacattctccacggg tattgtatctgtgagctggattgcatcaatgccgcctccaaaatttacatgcagatgttg ctgtgcccggatccggccgtgagcttctcttgcaagcaagcgctgattcgggtgctgagg cccaggaacaagcggagacacgtgaccttgccctcttcccctcgaagcaacaccccaatg ggcgacaaagacgattatgacgatgatgatgccgatgacaaattgcaggcctccagcctg cccagcggagaggacattcggcaggagagccaggagcaaaacgaggtggaccacggagac ttcgagatggtgtctgaatcgatggtcctggaaacagctgacaatgtgaacaacgggaac ccgtctcccctggaggctctcctggccggggccgagggcttcccccccatgctggacatc ccccccgatgccgatgatgaaaccatggtcgagctggccattgctttgagcctgcaacag gatcagcaaggcagcagcagcagcgctctcggcctgcagagcctgggactgtctggccag gcccccagctcttcctcgctcgatgctgggactctttcagacaccactgcatcagctcca gcttctgatgacgagggtagcactgcagcgacggacggctccacgctccgcacctccccg gctgaccacgggggcagcgtgggttccgagagcggcgggagcgcagtggactcggtggcc ggcgagcacagtgtgtccggccgcagcagcgcatacggagacacggcggctgagggccat cctgcgggacctgggagcgtcagctccagcacgggggccatcagcaccaccacggggcag caggagggcgaaggatctgaaggcgagggcgaaggggaaggggatgtccatgccagcaac aggctgcacatggtccgtttgatgctgctggaacggctgctgcagacccttccccagctg aggaacgtcggcggggtccgggccatcccctacatgcaggtgatcctgatgctgaccaca gacctcgatggtgacgaagagaaggacaagggagcgctcgataaccttcttgcgcagttg atcgccgagctctgcatggagaagaaggacgtgtccaagaaaaatgagcggtccgccctc aacgaagtccacttggtgatcatgaggcttctgagcgtcttcatgtcccgaaccaagtct ggatcgaaatcatccatttgcgagtcctcctccctgatctcaagtgccacggcagctgcc ttgctgagctctggagccgtggactattgccttcatgtcttgaagtccctcctggactac tggaagagccaacagaacgacgaggagcctgtcaccgccagccagctgctgaaaccccac accacctcctctcccccagacatgagcccattcttcctgcggcagtacgtcaagggtcac gcggccgacgtctttgaggcctacacgcagcttttgacagagatggtcctgcggctgcct taccagatcaagaaaatcgccgacaccaactcccgcatcccgccacccgtctttgaccat tcgtggttctacttcctctccgagtacctgatgatccagcagaccccctacgtgcgccgc caggtccgcaaactcttgcttttcatctgcggctccaaggagaaataccgccagctccgg gacctgcacaccctcgattcccacgtccgggggatcaagaagctgctggaggagcaaggc attttcctgcgtgccagcgtggtcacagccagctccggctccgccctgcagtatgacacc ctcatcagtttgatggagcacctgaaggcctgtgcggaaattgccacccagcgtacggtc aactggcaaaagttctgcatcaaagacgactcggtcctctatttcctcctgcaagtcagc ttcctggttgacgagggcgtgtcgcccgtcctcctgcagctgctctcctgcgccctctgt ggcagcaaggttctctctggcacggcttcggctgggtcgtcgggcacttcggcctcagct cctggaggctctggggccggccagccaactgggcagagcaaatcgtccaccaagaagagc aagaaggaagacaaggagaaagagcgagagggcgagggttcctctggcagccaggaagac cagctctgcacggccctggtgaaccagctgaacaaattcgccgacaaggagaccctgatt caattcctgcgctgcttcctgctggagtccaactcgtcgtcggtccgttggcaggcccac tgcctgaccctccacatctaccggaactcaaacaagtcccagcaagagctgctgctggat ctcatgtggtcgatctggccggagctgccggcgtacgggcggaaggccgcgcagttcgtg gacctcctgggctatttctctttgaaaacccagcagacggagaagaagttcaaggaatac tcccaaaaggccgtggagatcctccggatgcagaaccacatcctgaccaatcaccccaac tcgaacatctacaacaccctctccggcctggtggagtttgacggctactatttggagagc gacccttgtctcgtctgcaacaacccagaagtgcctttctgctacatcaagctctcctcc atcaaggtcgacacccggtacaccaccacccagcaggtggtcaagcttatcggcagccac accatcagcaaggtgacggtcaagatcggagacctgaagcgcaccaagatggtacggacc atcaacctctactacaacaaccggacagtgcaggccatcgtggagctgaagaacaagcca gcccgctggcacaaagccaagaaggttcagctgactcccggccagaccgaggtgaagatc gaccttcccctgcccattgtggcttccaacctgatgatcgagtttgccgacttctacgag aactaccaggcctccacggagaccttgcagtgcccccgatgcagcgcctctgtccccgcc aatcctggagtgtgcggaaactgcggggagaacgtctaccagtgccacaagtgccggtcg atcaactacgacgagaaggaccccttcctctgcaacgcctgcggcttctgcaaatacgcc cgctttgatttcatgctgttcgccaagccgtgctgcgccgtggatcccatcgaaaacgaa gaggaccggaagaaggcggtgaccaatatcaacaccctcctggacaaggctgaccgggtg tatcaccagctcatgggccaccgaccccagttggagaacctgctctgcaaagtgaatgag gccgcgcctgaaaagccgcaggatgactccgggggcagcggaggaatcagttccacctca gccagcgtgaacagatacattctgcagctggcccaggagtactgtggcgattgcaagaac tcgtttgacgagctctccaagatcatccagaaagtgtttgcctcccggaaggagctcctg gaatacgatctccagcagagagaggccgccagcaagtcctcccgctcagcagtccagccc accttcaccgccagccagtaccgtgccctctcggtcttgggctgcggccatacctcctcc accaaatgctatggttgcgcctcagctgtcacagagcactgcatcacgctgctccgcgcc ttggccaccaacgccgccatccgccacatcctggtctcccagggcctcattcgggagctc ttcgactacaacctgcgccgaggggccgccacgatgcgggaggacgtccgtcagctcatg tgccttctcaccagagacaacccagaagccacccagcagatgaacgacctcatcatcagc aaggtgtctgcagctctgaagggccactgggccaatcctgacctggccagcagtcttcag tacgagatgctgctgctgacagactctatctccaaggaagacagttgctgggaactgcgg ctgcgctgcgccctcagcctcttcctcatggccgtgaacatcaagacgccggtggtggtg gaaaacatcacgctcatgtgcttgcgcatcctgcagaagctgatcaagcccccggctcca accagcaagaagaacaaggtacctgccctgcttgcccaccttgaagccaacgggaagtcc cccggccgaaccgagcttcggcacctgtacctgacggagaagtacgcctggaagtggaag cagttcatgagcaagcgggggaagagaacctgccccctggacctcaagctgggacacaac aactggttgcggcaggtcttgttcaccccagcaacgcaagcagcccggcaggcagcctgc accattgttgaagctctggccaccatccccagccggaagcagcaagtcctcgacctgctg accagctacctggatgagctgagcgtggcaggcgagtgtgccgcagaatacctggccctc tatcagaagctcatcaagccggcccgctggaaagtctacttggcagccaggggagtcctg ccttatgttggcaacctgattaccaaggagatcgcccgtctcctggccttggaggaagcc acgctcagcaccgacctgcagcagggctacgctctgaagagcatcaccggcctcctctcc tcctttgtggaagtggagtcaatcaagcgtcacttcaagagccgcctggtggggacggtg ctgaacggctacctctgcctgcggaagctggtggtgcagcgcaccaagctgatcgacgag acccaggacatgctgctcgagatgctggaggacatgaccacaggcacagaatctgagacc aaagctttcatggctgtgtgcatcgaaacagccaagcgctacagcctggacgactaccgg acccccgtcttcatctttgagcgcctctgcagcataatctacccggaggagaacgaggtg acggagttctttgtcaccctcgagaaggaccctcagcaggaggatttcctgcaggggcgg atgcccggaaacccctacagcagcaacgagccgggcattgggccgctgatgcgggacatc aagaacaagatctgccaggactgcgacttggtggctctgctggaagacgacagcgggatg gagcttttggtgaacaacaagatcatcagcttggacctcccggtggccgaagtgtacaag aaagtctggtgtccgacgaacgagggcgaacccatgaggataatttatcgcatgcgaggc ctgctgggggatgcgacagaagaattcatcgagtcgctggactccactacagatgaagag gaggatgaggaagaggtttacaagatggcgggagtcatggcgcaatgcggggggctgggc tgcatgctcaaccgcttgaccgggatcaaagacttcaagcaaggccggcatctgctgacg gtcctgctgaagctcttcagctactgcgtcaaagtgaaggtcaatcgccagcagctggtg aagctggagatgaacaccctcaacgtcatgctggggacgctgaacttggctttggtggcc gaacaagagagcaaggacagcgggggagcggccgtggccgagcaggtgctgagcatcatg gagattatcctggacgagtccaatgcggagccgctgagcgaggacaagggaaacctgctg ctgacgggcgacaaggaccagctggtgatgctgctggaccagatcaacagcacgtttgtc cgctccaaccccagcgtcctgcagggcctcctgcgcatcatcccttatctgtccttcggg gaaacggagaagatggagatcctggtggaccgcttcaagccctactgcagcttcgacaag tacgacgaggaacacagtggggacgacaaggtcttcctggactgtttctgcaaaattgca gcaggcatcaagaacaacagcaatgggcacctgctgaaggacctcatcctgcagaggggg atcacgcagagtgccttggactacatgaagaagcatatccccagcgccaagaatttggac gccgacgtgtggaagaagttcctgtctcggccagccctcccgtttatcctccgnnnnnnn nnnnnnnnnnnnnnnnnnncccctccctaccaggcactgattgggaccgattcgatctcc aacttacacaagctggagcaggtttccagtgacgaagggatcgggaccctggccgagaac ctcctggaagccttgcgggagcacccggacgtgaacaagaagattgacgcggcccgcagg gagacacgggcggagaagaagcggatggccatggccatgcgccagaaggctctgggcacg ctaggcatgacgacgaacgaaaaggggcaggtggtgacgaagacggcgctcctgaagcag atggaggagctgatcgaagagcccggcctgacctgctgcatctgccgggagggctacaag ttccagcccacaaaagtcctgggcatctacaccttcaccaagcgggtggccctggaggag ttcgagaacaagcctcggaagcagcagggctacagcaccgtctcgcacttcaacattgtc cactacgactgccacctggcagcggtgaggctggcgcgtggccgcgaggagtgggagagc gccgccctgcagaacgccaacaccaaatgcaacggcctcctgccagtctgggggccacac gtcccagaatccgccttcgccacctgcttggcaaggcacaacacttacctccaggaatgc acggggcagcgggagcccacctaccagctcaacgttcatgacaccaagctgctcttcctc cggtttgccacggagcagtccttcagcgtggacacgggcggtggagggcgggagagcaac atccacctcatcccctacatcatccacacggtgctttacgtcctcaacacaacgcgtgcg acctctcgagaagagaagaacctgcagagcttcctggaacagccgaaggagaagtgggta gagagtgccttcgaggtggacgggccccactactacactgtcctggcgcttcacatcctg ccccctgagcgatggaaggcagtgcgcattgacatcctgaagcgtctgctggtcatctct cacgcccgggtggtgtcgcctgggggagcgagcaagctaacggacaaagcagtgaaggac tacgcggcctatcgctccagcctcctcttctgggccctcgttgatctcatttacaacatg ttcagaaaggtgcctacgagtaacacagaggggggctggtcctactctctggccgagtac atccgccagaacgacatgcccatctacgaggcggccgaccgagccctgaagtccttccag gaggagttcatgcctgcggagaccttctcagagttcctggacgtggccggcttgttgtca gaaatctgcgaccccgatggcttcctcaaagacctcttcaactctcttccctga

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