KEGG   Python bivittatus (Burmese python): 103057663
Entry
103057663         CDS       T03091                                 
Symbol
PLCB4
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
pbi  Python bivittatus (Burmese python)
Pathway
pbi00562  Inositol phosphate metabolism
pbi01100  Metabolic pathways
pbi04020  Calcium signaling pathway
pbi04070  Phosphatidylinositol signaling system
pbi04081  Hormone signaling
pbi04082  Neuroactive ligand signaling
pbi04261  Adrenergic signaling in cardiomyocytes
pbi04270  Vascular smooth muscle contraction
pbi04310  Wnt signaling pathway
pbi04371  Apelin signaling pathway
pbi04540  Gap junction
pbi04621  NOD-like receptor signaling pathway
pbi04912  GnRH signaling pathway
pbi04916  Melanogenesis
Module
pbi_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:pbi00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    103057663 (PLCB4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    103057663 (PLCB4)
   04371 Apelin signaling pathway
    103057663 (PLCB4)
   04020 Calcium signaling pathway
    103057663 (PLCB4)
   04070 Phosphatidylinositol signaling system
    103057663 (PLCB4)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    103057663 (PLCB4)
   04081 Hormone signaling
    103057663 (PLCB4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    103057663 (PLCB4)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    103057663 (PLCB4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103057663 (PLCB4)
   04916 Melanogenesis
    103057663 (PLCB4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103057663 (PLCB4)
   04270 Vascular smooth muscle contraction
    103057663 (PLCB4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pbi04131]
    103057663 (PLCB4)
Enzymes [BR:pbi01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     103057663 (PLCB4)
Membrane trafficking [BR:pbi04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    103057663 (PLCB4)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    103057663 (PLCB4)
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2 PLC-beta_C EF-hand_7 EF-hand_6
Other DBs
NCBI-GeneID: 103057663
NCBI-ProteinID: XP_025023639
UniProt: A0A9F5IZF5
LinkDB
Position
Unknown
AA seq 1206 aa
MAKPYEFNWQKPVPSFLQDGAIFDRYEEESFVFEPSCLFKVDEFGFFLSWKSEGKEGQVL
ECSLINSIRFGAVPKDPKILAALEAVSKAENELEGRIVCVCSGTDLVNINFTYMVAESTE
DAKQWVDGLRSIIRNFRANNVCPMTCLKKHWMKLAFLTNTNGKIPVRSITRTFASGKTEK
VIFQALKELGLPSGKNDEIEPSAFTYEKFYELTQKICPRTDIEELFRKINGDKTDYLTVD
QLVSFLNEHQRDPRLNEILFPFFDPKRAMQIIETYEPDEDLKNKGVMSSDGFCRYLMSDE
NAPVFLDRLELYQEMEHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSDYPVILSFENHCSKYQQYKM
SKYCEDIFGDLLLKQPLETHPLESGRPLPSPNDLKRKILIKNKRLKPEVEKKQLETLKSM
MEAGETAAPVSILEDDNEEEIESGDQEEEAHPEYKFGSELSADDLSQKESVANHIKKAVD
DSEQENNKKGVITAEDEQAWMASYKYVGATTNIHPYLSTLINYAQPVKFQGFSVAEERNI
HYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVS
LNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVI
SGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEECFVFRKVILPDLA
VLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGF
GDIVDALSDPKKFLSVMEKRADQMRAMGIETSDIADVPNDTSKNDKKGKTNNAKANVTPQ
TSSEVRSNAISSTGPGTEIKKGIDLIPQIKIEDLKQMKAYIKHLKKQQKELTALKKRHAK
EHSIMQKLHCTQVDKMVAQYDKEKLAYEKLLEKAIKKKGGNNCLEMKKETEGKIQMLTSD
HKSKVKEIVAQHTKEWSEMINTHSAEEQEMRDLHLSQQCELLKKLLINVHEQQTQQLKLS
HDRESKEMRANQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMK
QSKEMDQLKKVQLEHLEILEKQNEQLLKSCHAVSQIQGQRDAADGEARGRDGPQACNSGI
KLQYPN
NT seq 3621 nt   +upstreamnt  +downstreamnt
atggcaaaaccatacgaatttaactggcagaagccagttccatcctttctacaggatgga
gctatttttgacagatacgaagaggaatcttttgtctttgagccaagctgcctctttaaa
gttgatgaatttggcttttttctgtcatggaaaagtgagggaaaggaagggcaagtttta
gaatgttccctgatcaatagtattcgctttggagcagtgccaaaggatccaaaaatacta
gctgctcttgaagctgttagtaaagcagaaaatgaacttgaaggacgaatagtgtgtgtc
tgtagtggcaccgatctggtgaacatcaacttcacatacatggtagcagaaagcactgaa
gacgctaagcaatgggttgatggactcagatcaatcatacgtaactttagagccaacaat
gtttgtcccatgacatgcctcaagaaacactggatgaaattggcatttctgactaatact
aatggcaaaattccagttagaagcattaccagaacttttgcgtcaggtaaaactgaaaag
gtgatctttcaggcacttaaggaattgggtcttcccagtggaaagaatgatgaaatagag
ccttcagcttttacttatgagaaattttatgaactgacccagaagatatgtcctcgtact
gatatagaggagctttttagaaaaatcaatggagacaaaacagattatttaacggtagac
caattagtgagctttctaaatgaacatcagcgagatcctcggctgaatgaaattctattt
ccattctttgatcctaaaagagcaatgcaaataattgaaacatatgaaccagatgaagat
ttgaaaaacaaaggtgtcatgtcaagtgatgggttttgtcggtacttgatgtcagatgag
aatgctcctgtcttcctagaccgtttagaactatatcaagaaatggaacatcctctggct
cactattttattagctcttcccacaacacatatctcacaggaagacagtttggtggaaag
tcatctgtggagatgtacagacaagtcctcttggctggatgcaggtgtgtcgaacttgac
tgctgggatggaaaaggtgaagatcaagaaccaataataacacatggaaaggccatgtgt
acagacattctgttcaaggatgtgattcaagctattaaggaaactgcctttgtaacatct
gactatcctgtcatcctgtcctttgaaaatcactgcagcaaataccaacaatacaaaatg
tcaaagtactgtgaagatatttttggagatcttctcttaaaacagccactagaaacacat
ccactcgaatcaggaaggcccttgccctccccaaatgatctgaaaagaaagattcttatt
aaaaacaaaaggttgaaaccagaggtggaaaaaaaacagcttgaaactttgaaaagtatg
atggaagctggtgaaacagctgctcctgtcagcatcttggaagatgataatgaagaggag
atagaaagtggggatcaagaagaggaagcacatccagagtataaatttggaagtgaactt
tctgcagatgacctgagccaaaaagaatctgtagctaatcacattaaaaaagctgtggac
gattctgaacaagaaaacaataaaaagggcgtgataaccgcagaagatgaacaagcgtgg
atggcttcttacaaatatgtaggtgccacaactaatatacatccgtacttatcaacattg
atcaactatgctcagcctgtaaaatttcaaggtttcagtgtagcagaagaacgcaacatt
cactacaacatgtcctcttttaatgagtctgtcgggttaggttatttgaagacccacgca
atcgaatttgtgaactataataaacggcaaatgagtcggatatatccaaagggaggccga
gtggattccagcaattacatgcctcaaattttctggaacgctggatgccagatggtctca
ctcaactatcagaccccagatctagcaatgcagttgaatcaggggaaatttgaatataac
gggtcctgtggataccttcttaaaccagatttcatgcggcgacctgatcggacatttgac
cctttttctgagactcctgtggatggtgttattgcagcaacttgttcagtacaggtcata
tctggtcaatttttatcagacaaaaaaattggtacttatgtagaggtggatatgtatggc
cttcccactgacacgatacgtaaggaattccgaacacggatggtgatgaacaatggctta
aatcctgtttacaatgaagaatgctttgtgttccgaaaggtgattctaccagatcttgcg
gtcttgaggatagcagtttatgatgacaacaacaagctgatcggtcagaggatattgcca
ctggatgggcttcaggcaggctatcgacacatttcccttcgaaatgaaggcaacaaacca
ttatctctaccaacaattttctgcaacattgtacttaaaacttatgtgcctgatggtttt
ggagatattgtggatgccttgtcagacccaaagaaatttttatctgtcatggagaaaaga
gcagaccagatgagagctatgggaattgaaacaagtgacatagctgatgttccaaatgac
acttcaaagaacgataagaagggcaaaactaataacgctaaagcaaatgttactcctcag
actagctctgaagtcagatcaaatgccatttccagtacaggacctggcacagaaattaag
aaaggtatagatcttattcctcaaataaagatagaggacttaaaacagatgaaggcatat
ataaagcatctgaaaaaacagcaaaaagagctgactgctttgaagaagaggcatgcaaag
gagcacagcatcatgcagaagttacactgcacacaagttgacaaaatggtagcccaatat
gacaaagagaagctagcttacgagaaactccttgagaaggcaatcaagaaaaaaggagga
aataattgtcttgagatgaaaaaagaaacagaaggtaaaattcagatgttaacatctgat
cataaatcaaaggtgaaagaaattgtggcacagcacaccaaagagtggtctgagatgatc
aacacccacagtgcggaagagcaagaaatgcgtgatctgcaccttagccagcagtgtgaa
ctactaaagaagctgttaattaatgtgcacgaacagcagacacaacaactaaaactttcc
catgacagggaaagcaaagaaatgcgggccaaccaagcaaagatttcaatggaaaacagt
aaagccataagccaagataaatctatcaaaaacaaagctgaaagagagaggcgtgtgagg
gagctgaatagcagtaacacaaagaagtttctggaggaaagaaaacggttggcaatgaag
caatcaaaggaaatggatcagttgaagaaagttcaacttgaacatctagaaattttggag
aaacaaaatgagcagcttttgaaatcctgtcatgcagtctctcaaattcaaggccaaaga
gatgcagcagatggtgaagctagaggcagagatggaccgcaggcctgcaacagtggtata
aagctccaataccccaactga

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