KEGG   Petaurus breviceps papuanus (sugar glider): 138144804
Entry
138144804         CDS       T10505                                 
Symbol
PLCB3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
pbrv  Petaurus breviceps papuanus (sugar glider)
Pathway
pbrv00562  Inositol phosphate metabolism
pbrv01100  Metabolic pathways
pbrv04015  Rap1 signaling pathway
pbrv04020  Calcium signaling pathway
pbrv04022  cGMP-PKG signaling pathway
pbrv04062  Chemokine signaling pathway
pbrv04070  Phosphatidylinositol signaling system
pbrv04071  Sphingolipid signaling pathway
pbrv04072  Phospholipase D signaling pathway
pbrv04081  Hormone signaling
pbrv04082  Neuroactive ligand signaling
pbrv04261  Adrenergic signaling in cardiomyocytes
pbrv04270  Vascular smooth muscle contraction
pbrv04310  Wnt signaling pathway
pbrv04371  Apelin signaling pathway
pbrv04540  Gap junction
pbrv04611  Platelet activation
pbrv04613  Neutrophil extracellular trap formation
pbrv04621  NOD-like receptor signaling pathway
pbrv04713  Circadian entrainment
pbrv04720  Long-term potentiation
pbrv04723  Retrograde endocannabinoid signaling
pbrv04724  Glutamatergic synapse
pbrv04725  Cholinergic synapse
pbrv04726  Serotonergic synapse
pbrv04728  Dopaminergic synapse
pbrv04730  Long-term depression
pbrv04742  Taste transduction
pbrv04750  Inflammatory mediator regulation of TRP channels
pbrv04911  Insulin secretion
pbrv04912  GnRH signaling pathway
pbrv04915  Estrogen signaling pathway
pbrv04916  Melanogenesis
pbrv04918  Thyroid hormone synthesis
pbrv04919  Thyroid hormone signaling pathway
pbrv04921  Oxytocin signaling pathway
pbrv04922  Glucagon signaling pathway
pbrv04924  Renin secretion
pbrv04925  Aldosterone synthesis and secretion
pbrv04926  Relaxin signaling pathway
pbrv04927  Cortisol synthesis and secretion
pbrv04928  Parathyroid hormone synthesis, secretion and action
pbrv04929  GnRH secretion
pbrv04933  AGE-RAGE signaling pathway in diabetic complications
pbrv04934  Cushing syndrome
pbrv04935  Growth hormone synthesis, secretion and action
pbrv04961  Endocrine and other factor-regulated calcium reabsorption
pbrv04970  Salivary secretion
pbrv04971  Gastric acid secretion
pbrv04972  Pancreatic secretion
pbrv04973  Carbohydrate digestion and absorption
pbrv05010  Alzheimer disease
pbrv05016  Huntington disease
pbrv05017  Spinocerebellar ataxia
pbrv05022  Pathways of neurodegeneration - multiple diseases
pbrv05142  Chagas disease
pbrv05143  African trypanosomiasis
pbrv05146  Amoebiasis
pbrv05163  Human cytomegalovirus infection
pbrv05200  Pathways in cancer
pbrv05415  Diabetic cardiomyopathy
pbrv05417  Lipid and atherosclerosis
Module
pbrv_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:pbrv00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    138144804 (PLCB3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    138144804 (PLCB3)
   04310 Wnt signaling pathway
    138144804 (PLCB3)
   04371 Apelin signaling pathway
    138144804 (PLCB3)
   04020 Calcium signaling pathway
    138144804 (PLCB3)
   04070 Phosphatidylinositol signaling system
    138144804 (PLCB3)
   04072 Phospholipase D signaling pathway
    138144804 (PLCB3)
   04071 Sphingolipid signaling pathway
    138144804 (PLCB3)
   04022 cGMP-PKG signaling pathway
    138144804 (PLCB3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    138144804 (PLCB3)
   04081 Hormone signaling
    138144804 (PLCB3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    138144804 (PLCB3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    138144804 (PLCB3)
   04613 Neutrophil extracellular trap formation
    138144804 (PLCB3)
   04621 NOD-like receptor signaling pathway
    138144804 (PLCB3)
   04062 Chemokine signaling pathway
    138144804 (PLCB3)
  09152 Endocrine system
   04911 Insulin secretion
    138144804 (PLCB3)
   04922 Glucagon signaling pathway
    138144804 (PLCB3)
   04929 GnRH secretion
    138144804 (PLCB3)
   04912 GnRH signaling pathway
    138144804 (PLCB3)
   04915 Estrogen signaling pathway
    138144804 (PLCB3)
   04921 Oxytocin signaling pathway
    138144804 (PLCB3)
   04926 Relaxin signaling pathway
    138144804 (PLCB3)
   04935 Growth hormone synthesis, secretion and action
    138144804 (PLCB3)
   04918 Thyroid hormone synthesis
    138144804 (PLCB3)
   04919 Thyroid hormone signaling pathway
    138144804 (PLCB3)
   04928 Parathyroid hormone synthesis, secretion and action
    138144804 (PLCB3)
   04916 Melanogenesis
    138144804 (PLCB3)
   04924 Renin secretion
    138144804 (PLCB3)
   04925 Aldosterone synthesis and secretion
    138144804 (PLCB3)
   04927 Cortisol synthesis and secretion
    138144804 (PLCB3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    138144804 (PLCB3)
   04270 Vascular smooth muscle contraction
    138144804 (PLCB3)
  09154 Digestive system
   04970 Salivary secretion
    138144804 (PLCB3)
   04971 Gastric acid secretion
    138144804 (PLCB3)
   04972 Pancreatic secretion
    138144804 (PLCB3)
   04973 Carbohydrate digestion and absorption
    138144804 (PLCB3)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    138144804 (PLCB3)
  09156 Nervous system
   04724 Glutamatergic synapse
    138144804 (PLCB3)
   04725 Cholinergic synapse
    138144804 (PLCB3)
   04728 Dopaminergic synapse
    138144804 (PLCB3)
   04726 Serotonergic synapse
    138144804 (PLCB3)
   04720 Long-term potentiation
    138144804 (PLCB3)
   04730 Long-term depression
    138144804 (PLCB3)
   04723 Retrograde endocannabinoid signaling
    138144804 (PLCB3)
  09157 Sensory system
   04742 Taste transduction
    138144804 (PLCB3)
   04750 Inflammatory mediator regulation of TRP channels
    138144804 (PLCB3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    138144804 (PLCB3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    138144804 (PLCB3)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    138144804 (PLCB3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    138144804 (PLCB3)
   05142 Chagas disease
    138144804 (PLCB3)
   05143 African trypanosomiasis
    138144804 (PLCB3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    138144804 (PLCB3)
   05016 Huntington disease
    138144804 (PLCB3)
   05017 Spinocerebellar ataxia
    138144804 (PLCB3)
   05022 Pathways of neurodegeneration - multiple diseases
    138144804 (PLCB3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    138144804 (PLCB3)
   05415 Diabetic cardiomyopathy
    138144804 (PLCB3)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    138144804 (PLCB3)
   04934 Cushing syndrome
    138144804 (PLCB3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pbrv04131]
    138144804 (PLCB3)
Enzymes [BR:pbrv01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     138144804 (PLCB3)
Membrane trafficking [BR:pbrv04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    138144804 (PLCB3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    138144804 (PLCB3)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PI-PLC-Y PH_14 PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 138144804
NCBI-ProteinID: XP_068922338
LinkDB
Position
Unknown
AA seq 1249 aa
MAGARPGVHALQLEPPAVPETLRRGSKFIKWDEEASSRNLVTLRVDPNGFFLYWTGPNME
VDTLDISSIRDTRTGRYARLPKDPKIREILGFGGPETRPEDKLVTIVAGPDPVNTTFLNF
MAVQEDVAKIWADELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKTFS
ADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPY
LTLEQLLDFVNQKQRDPRLNEVLYPPLRPAQARLLIEKYEPNQQFLERDQMSMEGFSRYL
GGEENSILPPEPLDLSDDMTQPLSSYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRC
VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPFPVILSFENHVDSAK
QQAKMAEYCRTIFGDALLIDPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHHPSLSPSDG
SVRKRPLEQSNSALSESSVVTEPPSPQLGSPSSEGCSTLSNGEDQLGCNPEPRKSIGERR
GRQEGRGRQVVGVRTRGLILVPPTDREAESEEEEEEEQADPKKTSTDEGTASSEVNATEE
MSTLVNYVEPVKFKSFEVARKRNKCYEMSSFVETKALEQLTKSPMEFVEYNKQQLSRIYP
KGTRVDSSNYMPQLFWNAGCQLVALNFQTLDLPMQLNAGVFEYNGRSGYLLKPEFMRRQD
KSFDPFTEGIVDGIVANALRVKVISGQFLSDRKVGIYVEVDLFGLPADTRRKYRTRASQG
NSFNPVWDEEPFDFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYICLRNEA
NQPLCLPALLIYTEASDYIPDDHQDYAEALFNPIKHVSLMDQRSKQLAALIGESEAAPET
PQELPSRQLGPQLSTGSIQGSLESGGSRPPGSCTSPTSPSISRPGQCDELIASILGEVSV
TPLAELQAHKSLGKLRSRQERDLRELQKKHQRKAAAHTRRLLSHLAQHQGEMEKRRKSGV
LDEEEEEEMRKYRELQKKQLQSLLDLREAQVDVEAERRQEYLRQAQLRLREIVLETHTAQ
LKKLKETSEKEKKELQKILDRKRHNSISEAKSREKHKKEAELTEINRRHITESVNSIRRL
EEAQKQRQERVVAGQQQVQEQLEEDEPKAVAQLAQECQAHRARLPQEIRQSLCSEMRVDE
DDLGSHDGPGMGTGSGHALGRASNGHALGGSTSNGHAPGIERQEENTQF
NT seq 3750 nt   +upstreamnt  +downstreamnt
atggccggcgcccggcccggggtccacgcgctgcagctggagcctccggccgtgcccgag
accttgcgacggggcagcaagttcatcaagtgggacgaggaggcttctagtcggaacctg
gtcacactccgagtagaccccaatggcttctttctctactggactggacctaacatggaa
gtggacactctagacatcagctccatccgggacacgcgaacaggccgctatgcccggctg
cccaaggaccccaagatccgggaaatcctgggttttggaggccctgagacgaggcctgag
gacaagctggtgaccatagtagctggccctgaccctgtcaacactacttttctcaacttc
atggctgtgcaggaagatgttgccaagatttgggcagatgagctattcaagttggccatg
aatatcctggcccagaacgcatcccgaaacaccttccttcgaaaagcgtataccaagtta
aaacttcaggtgaatcaggacgggcgcatcccagtcaaaaacatccttaaaacgttctct
gctgacaagaaacgagtggagacggcgctggagtcctgcggcctcaactttaacaggagc
gagtcgatccggccagacgagttttccctggagatctttgaaagattcctcaataaactg
tgtctccggccagacatagacaagatcctgctggagattggtgctaaggggaagccgtac
ctgaccttagagcagctcctggactttgtcaaccagaagcagagagacccccggctgaac
gaggtcctataccccccactgcggccggcccaggcccgccttctcatcgagaagtatgag
cccaatcagcaattcttggagcgagaccagatgtccatggaaggcttcagtcgctacctg
ggtggggaggagaacagcattctgccaccagagcccctggacctgagcgatgacatgacc
cagccccttagctcttacttcatcaattcttcccacaacacctacctcacagcggggcag
ctggcagggacgtcgtccgtggagatgtaccggcaggcgctcctctggggctgccgctgt
gtggagctggacgtgtggaagggccggccgccggaggaggaacccttcatcacgcatggc
ttcaccatgaccacggaagtgccgctgcgcgatgtgttggaggcgatcgcagagacggcc
ttcaagacgtcgcccttccctgtcatcctctcctttgagaaccacgtggactcggcgaag
cagcaggccaagatggcggagtactgccgcaccatctttggggatgcgctgctcatagac
ccactggataagtaccctctggccccaggagtgcccttgcccagccctcaggacctgatg
ggcagaatcctggtgaagaataaaaagcggcaccacccgtccctgagcccctccgatggc
tcagtgcgcaagcgacccttggagcagagcaactcagccctgagcgagagttccgtggtc
actgagccgccttccccacagcttggctcccccagctctgagggctgctctactctgagc
aatggagaggaccagctgggctgcaatcccgagccccgaaaatccattggtgagaggagg
ggtaggcaagagggaaggggccgccaggtggtgggggtgaggacacggggcttgatcctt
gttccccccacagaccgagaggcagagagtgaggaggaggaggaggaagaacaggctgac
cccaagaagacctcgacagacgagggcacggccagcagcgaggtcaacgccacagaggag
atgtccactctcgtcaactacgttgagcccgtcaagttcaagtccttcgaggtggcccgg
aagcggaacaagtgctatgagatgtcgtcctttgtggagaccaaggcattggagcagctc
accaagagccccatggagtttgtggaatacaacaagcagcagcttagtcgcatctacccc
aaaggcacccgtgtggactcctccaattacatgccgcagctgttctggaatgccggctgt
cagctcgtcgccctcaatttccagaccctggacctcccgatgcagctgaacgctggtgtg
tttgagtacaatgggcgcagtggctacctgctcaagccggagttcatgcggcgccaagac
aagtcctttgacccgttcacggaaggcatcgtggatggcatcgtagccaacgctctgcgg
gtcaaggtgatctctggacagtttctgtcggacaggaaggttggcatctatgtggaggtg
gatctttttggccttcctgcggacacgcggcgcaaataccgcacccgggcttcccagggc
aactcctttaaccctgtgtgggatgaagaaccctttgacttccccaaggtggtactgccc
acactagcctccctacgtattgcggcctttgaggaagggggcaagtttgtggggcaccgc
atcctgccagtctctgccatccgctcagggtaccattacatctgcctgaggaatgaggcc
aaccagcccctgtgtctgcctgccctgcttatctacacagaggcttctgactatatccct
gatgatcaccaggactatgctgaggctttgttcaaccccatcaagcatgtcagcctcatg
gaccagaggtcaaaacagttggcagcattgattggtgagagtgaggcggctcctgagacc
ccacaggagctgccttctcgccagctgggtcctcagctgtccacaggctccatacaaggc
tccctggaatctggaggctcccggcctcctggctcctgcacctctcccaccagcccttcc
ataagcagaccaggtcagtgtgatgagctcattgccagcatcctgggagaggtatctgtg
actcccctggcggagctgcaggcccacaagtccctggggaagcttcgaagccggcaggag
cgcgaccttcgcgagctgcagaagaaacaccagcgcaaggcggcggcacacacacggcgg
ctcctcagccacctggcccagcaccagggagaaatggaaaagaggcgcaagagtggggtg
ctggatgaggaagaggaggaagagatgaggaagtaccgagagctgcaaaagaaacagctt
cagagtctgttggatctgagggaggctcaagttgatgtggaagctgaacgtcgtcaggaa
tacctgagacaggcccagcttcgccttcgggagattgtccttgaaacacatacggctcag
ttgaaaaaactgaaggagaccagtgagaaggagaagaaggagctgcagaagatcctggac
cggaagagacataatagcatttctgaggccaagtcccgggagaagcacaagaaggaggcg
gagctgactgagataaaccgtcggcacatcacggaatctgtcaactccatccgaaggctg
gaggaagcccagaagcagcgccaggagcgggtggtggctggacagcagcaggttcaggaa
cagctggaagaggacgagccaaaggcagtagcccagctggcccaggagtgccaggcccat
cgggcacggctgccacaggagatccggcagagcctgtgcagtgagatgcgtgtggacgag
gacgacctgggctcccatgacgggcccggcatgggcaccggcagtgggcacgcgctgggc
agagctagcaacgggcacgccctggggggcagcaccagcaacgggcacgccccagggatc
gagaggcaggaagagaacacccagttctga

DBGET integrated database retrieval system