KEGG   Petaurus breviceps papuanus (sugar glider): 138154225
Entry
138154225         CDS       T10505                                 
Symbol
PIK3CD
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
pbrv  Petaurus breviceps papuanus (sugar glider)
Pathway
pbrv00562  Inositol phosphate metabolism
pbrv01100  Metabolic pathways
pbrv01521  EGFR tyrosine kinase inhibitor resistance
pbrv01522  Endocrine resistance
pbrv01524  Platinum drug resistance
pbrv04012  ErbB signaling pathway
pbrv04014  Ras signaling pathway
pbrv04015  Rap1 signaling pathway
pbrv04024  cAMP signaling pathway
pbrv04062  Chemokine signaling pathway
pbrv04066  HIF-1 signaling pathway
pbrv04068  FoxO signaling pathway
pbrv04070  Phosphatidylinositol signaling system
pbrv04071  Sphingolipid signaling pathway
pbrv04072  Phospholipase D signaling pathway
pbrv04081  Hormone signaling
pbrv04140  Autophagy - animal
pbrv04145  Phagocytosis
pbrv04150  mTOR signaling pathway
pbrv04151  PI3K-Akt signaling pathway
pbrv04152  AMPK signaling pathway
pbrv04210  Apoptosis
pbrv04211  Longevity regulating pathway
pbrv04213  Longevity regulating pathway - multiple species
pbrv04218  Cellular senescence
pbrv04360  Axon guidance
pbrv04370  VEGF signaling pathway
pbrv04380  Osteoclast differentiation
pbrv04510  Focal adhesion
pbrv04517  IgSF CAM signaling
pbrv04518  Integrin signaling
pbrv04550  Signaling pathways regulating pluripotency of stem cells
pbrv04611  Platelet activation
pbrv04613  Neutrophil extracellular trap formation
pbrv04620  Toll-like receptor signaling pathway
pbrv04625  C-type lectin receptor signaling pathway
pbrv04630  JAK-STAT signaling pathway
pbrv04650  Natural killer cell mediated cytotoxicity
pbrv04660  T cell receptor signaling pathway
pbrv04662  B cell receptor signaling pathway
pbrv04664  Fc epsilon RI signaling pathway
pbrv04666  Fc gamma R-mediated phagosome formation
pbrv04668  TNF signaling pathway
pbrv04670  Leukocyte transendothelial migration
pbrv04722  Neurotrophin signaling pathway
pbrv04725  Cholinergic synapse
pbrv04750  Inflammatory mediator regulation of TRP channels
pbrv04810  Regulation of actin cytoskeleton
pbrv04910  Insulin signaling pathway
pbrv04914  Progesterone-mediated oocyte maturation
pbrv04915  Estrogen signaling pathway
pbrv04917  Prolactin signaling pathway
pbrv04919  Thyroid hormone signaling pathway
pbrv04923  Regulation of lipolysis in adipocytes
pbrv04926  Relaxin signaling pathway
pbrv04929  GnRH secretion
pbrv04930  Type II diabetes mellitus
pbrv04931  Insulin resistance
pbrv04932  Non-alcoholic fatty liver disease
pbrv04933  AGE-RAGE signaling pathway in diabetic complications
pbrv04935  Growth hormone synthesis, secretion and action
pbrv04960  Aldosterone-regulated sodium reabsorption
pbrv04973  Carbohydrate digestion and absorption
pbrv05010  Alzheimer disease
pbrv05017  Spinocerebellar ataxia
pbrv05020  Prion disease
pbrv05100  Bacterial invasion of epithelial cells
pbrv05132  Salmonella infection
pbrv05135  Yersinia infection
pbrv05142  Chagas disease
pbrv05146  Amoebiasis
pbrv05160  Hepatitis C
pbrv05161  Hepatitis B
pbrv05162  Measles
pbrv05163  Human cytomegalovirus infection
pbrv05164  Influenza A
pbrv05165  Human papillomavirus infection
pbrv05166  Human T-cell leukemia virus 1 infection
pbrv05167  Kaposi sarcoma-associated herpesvirus infection
pbrv05168  Herpes simplex virus 1 infection
pbrv05169  Epstein-Barr virus infection
pbrv05170  Human immunodeficiency virus 1 infection
pbrv05171  Coronavirus disease
pbrv05200  Pathways in cancer
pbrv05203  Viral carcinogenesis
pbrv05205  Proteoglycans in cancer
pbrv05206  MicroRNAs in cancer
pbrv05207  Chemical carcinogenesis - receptor activation
pbrv05208  Chemical carcinogenesis - reactive oxygen species
pbrv05210  Colorectal cancer
pbrv05211  Renal cell carcinoma
pbrv05212  Pancreatic cancer
pbrv05213  Endometrial cancer
pbrv05214  Glioma
pbrv05215  Prostate cancer
pbrv05218  Melanoma
pbrv05220  Chronic myeloid leukemia
pbrv05221  Acute myeloid leukemia
pbrv05222  Small cell lung cancer
pbrv05223  Non-small cell lung cancer
pbrv05224  Breast cancer
pbrv05225  Hepatocellular carcinoma
pbrv05226  Gastric cancer
pbrv05230  Central carbon metabolism in cancer
pbrv05231  Choline metabolism in cancer
pbrv05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pbrv05415  Diabetic cardiomyopathy
pbrv05417  Lipid and atherosclerosis
pbrv05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pbrv00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    138154225 (PIK3CD)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    138154225 (PIK3CD)
   04014 Ras signaling pathway
    138154225 (PIK3CD)
   04015 Rap1 signaling pathway
    138154225 (PIK3CD)
   04370 VEGF signaling pathway
    138154225 (PIK3CD)
   04630 JAK-STAT signaling pathway
    138154225 (PIK3CD)
   04668 TNF signaling pathway
    138154225 (PIK3CD)
   04066 HIF-1 signaling pathway
    138154225 (PIK3CD)
   04068 FoxO signaling pathway
    138154225 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    138154225 (PIK3CD)
   04072 Phospholipase D signaling pathway
    138154225 (PIK3CD)
   04071 Sphingolipid signaling pathway
    138154225 (PIK3CD)
   04024 cAMP signaling pathway
    138154225 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    138154225 (PIK3CD)
   04152 AMPK signaling pathway
    138154225 (PIK3CD)
   04150 mTOR signaling pathway
    138154225 (PIK3CD)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    138154225 (PIK3CD)
   04517 IgSF CAM signaling
    138154225 (PIK3CD)
   04518 Integrin signaling
    138154225 (PIK3CD)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    138154225 (PIK3CD)
   04140 Autophagy - animal
    138154225 (PIK3CD)
  09143 Cell growth and death
   04210 Apoptosis
    138154225 (PIK3CD)
   04218 Cellular senescence
    138154225 (PIK3CD)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    138154225 (PIK3CD)
   04550 Signaling pathways regulating pluripotency of stem cells
    138154225 (PIK3CD)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    138154225 (PIK3CD)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    138154225 (PIK3CD)
   04613 Neutrophil extracellular trap formation
    138154225 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    138154225 (PIK3CD)
   04625 C-type lectin receptor signaling pathway
    138154225 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    138154225 (PIK3CD)
   04660 T cell receptor signaling pathway
    138154225 (PIK3CD)
   04662 B cell receptor signaling pathway
    138154225 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    138154225 (PIK3CD)
   04666 Fc gamma R-mediated phagosome formation
    138154225 (PIK3CD)
   04670 Leukocyte transendothelial migration
    138154225 (PIK3CD)
   04062 Chemokine signaling pathway
    138154225 (PIK3CD)
  09152 Endocrine system
   04910 Insulin signaling pathway
    138154225 (PIK3CD)
   04923 Regulation of lipolysis in adipocytes
    138154225 (PIK3CD)
   04929 GnRH secretion
    138154225 (PIK3CD)
   04915 Estrogen signaling pathway
    138154225 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    138154225 (PIK3CD)
   04917 Prolactin signaling pathway
    138154225 (PIK3CD)
   04926 Relaxin signaling pathway
    138154225 (PIK3CD)
   04935 Growth hormone synthesis, secretion and action
    138154225 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    138154225 (PIK3CD)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    138154225 (PIK3CD)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    138154225 (PIK3CD)
  09156 Nervous system
   04725 Cholinergic synapse
    138154225 (PIK3CD)
   04722 Neurotrophin signaling pathway
    138154225 (PIK3CD)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    138154225 (PIK3CD)
  09158 Development and regeneration
   04360 Axon guidance
    138154225 (PIK3CD)
   04380 Osteoclast differentiation
    138154225 (PIK3CD)
  09149 Aging
   04211 Longevity regulating pathway
    138154225 (PIK3CD)
   04213 Longevity regulating pathway - multiple species
    138154225 (PIK3CD)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    138154225 (PIK3CD)
   05206 MicroRNAs in cancer
    138154225 (PIK3CD)
   05205 Proteoglycans in cancer
    138154225 (PIK3CD)
   05207 Chemical carcinogenesis - receptor activation
    138154225 (PIK3CD)
   05208 Chemical carcinogenesis - reactive oxygen species
    138154225 (PIK3CD)
   05203 Viral carcinogenesis
    138154225 (PIK3CD)
   05230 Central carbon metabolism in cancer
    138154225 (PIK3CD)
   05231 Choline metabolism in cancer
    138154225 (PIK3CD)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    138154225 (PIK3CD)
  09162 Cancer: specific types
   05210 Colorectal cancer
    138154225 (PIK3CD)
   05212 Pancreatic cancer
    138154225 (PIK3CD)
   05225 Hepatocellular carcinoma
    138154225 (PIK3CD)
   05226 Gastric cancer
    138154225 (PIK3CD)
   05214 Glioma
    138154225 (PIK3CD)
   05221 Acute myeloid leukemia
    138154225 (PIK3CD)
   05220 Chronic myeloid leukemia
    138154225 (PIK3CD)
   05218 Melanoma
    138154225 (PIK3CD)
   05211 Renal cell carcinoma
    138154225 (PIK3CD)
   05215 Prostate cancer
    138154225 (PIK3CD)
   05213 Endometrial cancer
    138154225 (PIK3CD)
   05224 Breast cancer
    138154225 (PIK3CD)
   05222 Small cell lung cancer
    138154225 (PIK3CD)
   05223 Non-small cell lung cancer
    138154225 (PIK3CD)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    138154225 (PIK3CD)
   05170 Human immunodeficiency virus 1 infection
    138154225 (PIK3CD)
   05161 Hepatitis B
    138154225 (PIK3CD)
   05160 Hepatitis C
    138154225 (PIK3CD)
   05171 Coronavirus disease
    138154225 (PIK3CD)
   05164 Influenza A
    138154225 (PIK3CD)
   05162 Measles
    138154225 (PIK3CD)
   05168 Herpes simplex virus 1 infection
    138154225 (PIK3CD)
   05163 Human cytomegalovirus infection
    138154225 (PIK3CD)
   05167 Kaposi sarcoma-associated herpesvirus infection
    138154225 (PIK3CD)
   05169 Epstein-Barr virus infection
    138154225 (PIK3CD)
   05165 Human papillomavirus infection
    138154225 (PIK3CD)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    138154225 (PIK3CD)
   05135 Yersinia infection
    138154225 (PIK3CD)
   05100 Bacterial invasion of epithelial cells
    138154225 (PIK3CD)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    138154225 (PIK3CD)
   05142 Chagas disease
    138154225 (PIK3CD)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    138154225 (PIK3CD)
   05017 Spinocerebellar ataxia
    138154225 (PIK3CD)
   05020 Prion disease
    138154225 (PIK3CD)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    138154225 (PIK3CD)
   05418 Fluid shear stress and atherosclerosis
    138154225 (PIK3CD)
   05415 Diabetic cardiomyopathy
    138154225 (PIK3CD)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    138154225 (PIK3CD)
   04932 Non-alcoholic fatty liver disease
    138154225 (PIK3CD)
   04931 Insulin resistance
    138154225 (PIK3CD)
   04933 AGE-RAGE signaling pathway in diabetic complications
    138154225 (PIK3CD)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    138154225 (PIK3CD)
   01524 Platinum drug resistance
    138154225 (PIK3CD)
   01522 Endocrine resistance
    138154225 (PIK3CD)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pbrv04131]
    138154225 (PIK3CD)
Enzymes [BR:pbrv01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     138154225 (PIK3CD)
Membrane trafficking [BR:pbrv04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    138154225 (PIK3CD)
SSDB
Motif
Pfam: PI3_PI4_kinase PI3Ka PI3K_p85B PI3K_rbd PI3K_C2 DUF5053
Other DBs
NCBI-GeneID: 138154225
NCBI-ProteinID: XP_068934892
LinkDB
Position
Unknown
AA seq 1046 aa
MPPGVDCPMEFWSKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVARQGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEDAAAQRQQLGWEAWMHYNFPLQLEPCARGLGA
AALRVPNRTLFVNVKFEGNEESFTFQVSPNDLPLALMACALKKRATVFRQSAMERPEDYT
LKVNGKYEYLYGNYPLHQFQYICNCLHNGLTPHLTMVHSSSILAMRDEQNNPPAQAPKLR
AKPPPIPVKKPSSVSLWSLEQPFCIELVQGSKVNADERMKLVVLAGLFHGNEMLCKTVSS
SEVTVCSEPVWKQRLEFDISICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWSSVPDEKGELLNPMGTVRSNPNTESAAALVICIPEVAP
HPVYYPTMEKILELGKNGEHGHFTEDEQQQLREILERKVAAELYEHEKDLVWKMRHEIQE
QFPEALARLLLVTKWNKHEDVAQMLFLLGSWPELPVLSALELLDFSFPDRHVGSFAIQSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSNHHMKALMKQGEALNKMKSLNDFVKVSSQKTTKPQTKELMHVCMR
QETYLEALSNVQSPLNPSTLLSEVCVEQCTFMDSKMKPLWIVYSNEEAGGGGDGHVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVSHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALERAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRS
YCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
NT seq 3141 nt   +upstreamnt  +downstreamnt
atgccccctggagttgactgtcctatggaattctggtccaaggaagaaaaccagagcgtg
gtggtagacttcttgttgcctacaggggtctatctgaacttccctgtctctcgaaatgcc
aacctcagcaccatcaaacaggtcctgtggcaccatgcccagtatgagcccctgttccac
atgctcagcgaccccgaggcctacgtcttcacctgcatcaaccagacggccgagcagcag
gagctggaggatgagcagcggcgcctctgcgacatccagcccttcctgcccgtgctgcgg
ctcgtggcccgccagggcgaccgcgtgaagaagctcatcaattcccagatcagcctcctc
atcgggaagggtctgcacgagtttgactctctacgggacccagaggtcaatgacttccgc
accaagatgcgccagttctgcgaagacgcagcggcccaacggcagcagctgggctgggag
gcctggatgcattacaacttcccgttacagctggagccctgtgcccggggcctgggggcc
gcggcactgcgcgtccccaacaggaccctctttgtcaacgtcaagtttgagggcaatgag
gaaagcttcaccttccaggtatctcccaacgaccttcccctggccctcatggcctgtgcc
ctcaagaagagggccaccgtgtttcggcagtccgccatggagcggccggaggactacacc
ctgaaggtgaacgggaagtacgagtacctgtatgggaactaccccctccaccagttccag
tatatctgcaactgcctccacaatgggctgaccccccatctcaccatggtccactcctcc
tccatcctggccatgcgagatgagcaaaacaacccccctgcgcaggccccaaagctccgt
gccaagcctcccccgattccagtgaagaagccgtcctctgtgtctctctggtccctggag
cagcccttctgcatcgagctggttcagggcagcaaggtgaacgctgacgagaggatgaag
ctcgtggtcctggctggtctcttccacggcaatgaaatgctgtgcaagacagtgtctagc
tctgaggtgactgtgtgctcagagcctgtgtggaagcagcgcctggagtttgacatcagt
atctgcgacctgccccgcatggcccggctctgcttcgccctttatgccgtcatcgagaag
gccaagaaggctcgctccaccaagaagaagtccaagaaggccgactgccctattgcttgg
gccaaccttatgctgtttgactacaaggaccagctgaagactggcgagtgctgcctgtac
atgtggtcctctgtccccgatgagaaaggggagctgctgaaccccatgggcactgtgcgg
agtaaccccaacactgagagtgctgccgcgctggtcatctgcattcctgaggtcgctcca
caccccgtgtactaccctacgatggagaagatcttggagctggggaaaaacggggagcat
ggacacttcacagaggatgagcagcagcagctgcgggagatcctggagagaaaggtggcc
gcagagctgtacgagcatgagaaggacctggtgtggaagatgcgccacgagatccaggag
cagttccccgaggccctggcccggctcctgctggtcaccaagtggaacaagcacgaggac
gtggcccagatgctcttcctgctgggctcctggcccgagctcccggtactgagcgccctg
gagctgctggacttcagcttccccgaccgccatgtgggctccttcgccatccagtccctg
aggaaactgacggatgacgagctcttccaatacctgctgcagttggtccaggtactcaag
tacgaatcgtacctggactgtgagttgaccaagttcctgctggaccgggccctggccaac
cgcaagattggccactttctcttctggcacctacgctctgagatgcacgtcccctctgtg
gccctgcgattcggcctcatcatggaggcctactgccgtggcagcaatcaccacatgaag
gcgctgatgaagcagggggaggcactgaacaaaatgaagtccctgaatgactttgtcaaa
gtgagctcccagaagaccaccaagccacagaccaaggagctgatgcatgtgtgtatgagg
caggagacgtacttagaggccctctcgaacgtgcagtctcccctgaaccccagtacctta
ctgtctgaagtctgcgtggagcagtgcaccttcatggactccaagatgaagcccctgtgg
attgtgtacagtaacgaggaggcaggcgggggcggagatggccacgtgggcatcatcttc
aagaatggtgatgacctccgccaggacatgctgacccttcagatgattcagctgatggat
gtgctgtggaagcaggaggggctggacctgaggatgaccccctatggctgcctctccacg
ggggaccggacggggctcattgaggtggtatcacactcggacaccatcgccaacatccag
ctcaacaaaagcaatatggcagcaacagcagccttcaataaggacgccctgctgaactgg
ctgaagtccaagaaccctggagaggccttggagcgagccattgaggaattcacgctgtct
tgtgcggggtactgcgtggcgacctacgtgctgggcattggagatcggcacagcgacaac
atcatgatccgggagagtgggcagctcttccatattgactttggccatttcttgggcaat
ttcaagaccaaatttggaatcaaccgtgagcgagtcccattcatcctcacttacgatttt
gtccacgtgatccaacaagggaagaccaacaacaatgagaagtttgagaggttccgcagt
tactgtgaaagggcatacaccatcctgcgtcgccacggcctcctcttccttcacctcttt
gcactgatgcgggcagcgggactgcccgaactcagctgctccaaagacatccagtatctc
aaggattccttggccttggggaaaacagatgaagaggccctgaagcacttccgagtgaaa
tttaacgaagcccttcgcgaaagctggaaaaccaaagtgaactggctggcccacaacgtg
tccaaagacaacaggcagtag

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