| Entry |
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| Symbol |
TOP2B
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| Name |
(RefSeq) DNA topoisomerase 2-beta
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| KO |
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| Organism |
pbrv Petaurus breviceps papuanus (sugar glider)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:pbrv00001]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
138161695 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:pbrv03032]
138161695 (TOP2B)
03036 Chromosome and associated proteins [BR:pbrv03036]
138161695 (TOP2B)
Enzymes [BR:pbrv01000]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
138161695 (TOP2B)
DNA replication proteins [BR:pbrv03032]
Eukaryotic type
DNA Topoisomerases
138161695 (TOP2B)
Chromosome and associated proteins [BR:pbrv03036]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
138161695 (TOP2B)
Centrosome formation proteins
Centriole proteins
138161695 (TOP2B)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1540 aa
MWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKISIDPESNIISIWN
NGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASKEYKHSFKQTWVNNMMKTSEPKIKYFDGDDYTCITFQPDLSKFKMEKLDKDIVALMT
RRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHELANERWDVC
LTLSEKGFQQISFVNSIATTKGGRHVDYVVDQIVGKLIEVVKKKNKAGVSVKPFQVKNHI
WVFVNCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIIESILNWVKFKAQ
TQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVSGLGVIGRDR
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYEDAESLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYSIPEFDEWKK
HIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITLAFSKKKIDD
RKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDNERSIPSLVD
GFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNLAQNFVGSNN
INLLQPIGQFGTRLHGGKDAASPRYIFTMLSTLSRLLFPSVDDNLLKFLYDDNQRVEPEW
YMPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDPHPMLPNYKNFKGTIQ
EIGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTPALISDYKEY
HTDTTVKFVVKMTEEKLVQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKKYETVQDILK
EFFDLRLNYYSLRKEWLVGMLGAESTKLNNQARFILEKIQGKVTIENRSKRDLIQMLVQR
GYESDPVKAWKEAQEKAAEEEESQNQRDDSSSDSGTTSGPDFNYILNMSLWCLTKEKVEE
LIKQRDNKGRELNDLKRKSPSDLWKEDLAAFVEELDKVEAQEREDALAGMTGKAIKGKVG
KPKIKKLQLEETMPSPHGRRIIPQITSAMKADASKKLLKKKKGDLDPTAVKVEFDEELGG
APAEGAGEDSLTISALAPKGPKPKREKKEPGTRVRKTPLSSNKSGAKKVKKRNPWSDDES
KSESDLEETEPVIIPRDSLLRRAAAERPKYTFDFSEEEDDADEDDNNDLEELKVKSSPVT
NDRDDEFIPSDGLDKDDYAFSPVKSKVTPEKSSHDKKTQDFGNLFSFPSYSQKSEDDATK
FDSGEEDSASVFSSSFALKSTEKPPSKTVAAKKAKLSSDAPPKPKRLPKQKKIEATNSDS
DSEFGIPKKTTAPKGKGRGAKKRKVSGSENEGEYNPGRKTSKTTPGKKSKKASFDQDSDV
DIFQADFHPEPPSLPRTGRARKEVKYFAESDEDVDFAMFN |
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| NT seq |
4623 nt +upstreamnt +downstreamnt
atgtgggtttatgatgaagatgtaggaatgaattgcagagaagttacttttgtgccaggc
ttatacaaaatctttgatgaaattcttgttaatgcagctgacaataagcagagggataag
aacatgacctgtatcaaaatttctattgatcctgaatctaacattatcagcatctggaat
aatggaaaaggcattcctgtagtggaacacaaagtagaaaaagtctatgttcctgcttta
atctttggacagcttttaacatctagtaactatgatgatgatgagaaaaaagttacaggt
ggtcgtaatggttatggtgcaaaactttgtaatattttcagtacaaaatttacagttgaa
actgctagtaaagaatataaacatagttttaaacagacctgggtgaataatatgatgaag
acttctgaacccaaaattaaatactttgatggagatgactatacatgtataacattccaa
ccggatctgtcaaaatttaagatggaaaagcttgacaaggatattgtggcccttatgact
agaagagcctacgacttggctggttcatgcaaaggggtcaaagtcatgtttaatgggaag
aagttgcctgtaaatggattccgcagttacgtagacctttacgtaaaggacaaattggat
gaaactggggttgccctgaaagttattcatgaacttgcaaatgaacgatgggatgtttgt
ctcacattgagtgaaaaaggcttccagcaaatcagctttgtaaatagtattgctacaaca
aaaggtggaaggcacgtagattatgttgtggatcagatcgttgggaaactgattgaagta
gttaagaaaaagaacaaagctggagtatcagtgaagccatttcaagtaaaaaaccacata
tgggtttttgttaactgtcttattgaaaatccaacttttgattcccagacaaaggaaaac
atgactctgcaacccaaaagctttgggtctaagtgtcaactgtctgagaaatttttcaaa
gcagcttccaactgtggtattatagaaagtattctgaactgggtcaaatttaaagctcag
actcaactgaacaagaagtgttcatcagtaaagtatagtaaaataaaaggcattcccaaa
ctggatgatgcaaatgatgcaggtggtaaacattccctagagtgcacactcatattaaca
gaaggagattctgcaaaatcattagcagtttctgggttaggtgtgattggaagagacaga
tatggagtctttccactcaggggtaaaattcttaatgttcgagaagcttcacataagcag
attatggaaaatgcagaaatcaacaacattattaaaatagttggtcttcagtataagaaa
agttatgaagatgcagaatctctgaaaaccttgcgttatggaaaaattatgattatgact
gatcaggatcaagatggctctcacataaagggcttacttattaattttattcatcataac
tggccttcacttttgaaacatggctttcttgaagagttcatcactcccattgtaaaggca
agcaaaaataagcaggagctttccttctatagtatacctgagtttgatgaatggaagaaa
catatagaaaaccagaaggcctggaaaataaaatactacaaagggttgggtaccagcaca
gctaaagaagcaaaggaatattttgctgacatggaaaggcatcggattttgtttagatat
gctggtcctgaagatgatgcagctattactctagcattcagtaagaagaagattgatgac
cgtaaagaatggttaacaaatttcatggaagatcgaagacagcgcaggttacatggcttg
ccagagcaatttttgtatggtacagccacaaagcatttgacttacaatgattttatcaac
aaggagttgattcttttctcaaactccgacaatgaaagatctataccctctcttgttgat
ggctttaaaccaggtcaacgaaaagttttgtttacctgttttaagaggaatgataaacgg
gaagtcaaagttgctcagttggctggatcagttgctgagatgtctgcttatcatcatgga
gaacaagcactaatgatgactatagtcaatttggcccagaactttgttggaagtaacaat
attaatttgcttcaacctattggtcagtttggaactaggcttcatggtggaaaagatgct
gcaagccctcgttatatttttacaatgttaagtactctatcaaggctgcttttcccttct
gtggatgacaacttgcttaagttcctttatgatgataaccagcgtgtagaacctgagtgg
tatatgcctattattcccatggttttaataaatggtgctgagggcattggtactggatgg
gcttgtaagcttcccaactatgatgctagagagattgtgaacaatgtcagacggatgttg
gatggcttggaccctcatcccatgcttccaaactacaaaaattttaaaggaacaatccaa
gaaattggccagaaccagtatgctgttagtggtgaaatatttgtagtggatagaaataca
gtagagatcacagagctgccagtcagaacatggacccaggtatacaaagaacaggtttta
gaacctatgctgaatggaacagacaaaacaccagcattaatttcggattataaagaatat
catacagatacaactgtgaaatttgtggtgaagatgaccgaagaaaaacttgtgcaagca
gaagctgctgggttgcataaagtctttaagcttcagaccactcttacttgtaattctatg
gtgctgtttgaccatatgggatgtctgaagaagtatgagactgtacaagatattctgaag
gaattctttgatttaaggttaaattattatagtttacgtaaggagtggcttgtgggaatg
ttgggggcagaatccaccaagctaaacaatcaagctcgcttcattctagagaagatacaa
gggaaagtcactatagagaataggtcaaagagagatttgattcaaatgttagtccagaga
ggttatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagag
gaagaatcacaaaaccagcgtgacgatagttcctctgattcaggcactacctcaggccct
gattttaactacatcttaaatatgtctttgtggtgtcttactaaagaaaaagttgaagaa
ctgattaagcagagagataataaagggagagaactcaacgaccttaaaagaaaatctcct
tcagatctctggaaagaagatttagcagcttttgttgaagaacttgataaagtggaagcc
caagaacgagaggatgctttggctggaatgactggcaaagcaataaaaggcaaagttggc
aaacccaagataaagaagcttcagttggaagagaccatgccctcgccccatggtagaagg
atcattccacagatcacctctgccatgaaggctgatgcaagcaaaaagttgctaaagaaa
aagaagggtgatcttgatcctacagcagtaaaagtggagtttgatgaggaattaggtgga
gcgccagcagaaggtgcaggagaagattcattgacaatatctgctcttgcacctaaagga
cccaaacccaaaagggagaaaaaggagcctggtaccagggtgagaaaaacacctctctct
tctaataaatccggtgcaaagaaagtgaagaaaagaaacccttggtctgatgatgaatcc
aagtcagaaagtgacttggaagaaactgaacctgtgattattccaagagactctctgctt
agacgagccgctgcggaaaggcctaaatatacttttgatttttcggaagaggaagatgat
gctgatgaagatgacaataatgatttagaggaattgaaagtaaagtcatctcctgtgaca
aatgacagagatgatgagttcattccctcagatggcttggataaggatgactatgccttt
tctccagtcaaatcaaaagtaactccagaaaaatcctcacatgacaagaaaacccaggac
tttgggaacctgttctcattcccttcttattcacagaagtcagaagatgatgcaacaaaa
tttgacagtggcgaagaggattctgcctctgttttttcatcttcatttgctctaaaatca
acagaaaaacctccaagtaaaacagtggctgccaaaaaggcaaagctatcttcagacgca
ccacctaagcccaagagacttcccaaacagaagaaaatagaagctacaaactctgactca
gattcagaatttggcattccaaagaagacaacagcaccaaaaggtaaaggccgaggcgca
aaaaaacggaaagtatctggctctgaaaatgaaggcgaatacaatcctgggaggaaaaca
tccaagacaacacctggcaagaaatccaagaaggcctcctttgaccaggattcagatgta
gacatcttccaggcagactttcaccccgagccgccatctcttcctcggacaggtcgcgcc
agaaaagaagtaaaatattttgcagagtctgacgaagatgttgattttgcaatgtttaat
taa |
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