Petaurus breviceps papuanus (sugar glider): 138169419
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Entry
138169419 CDS
T10505
Symbol
CYP17A1
Name
(RefSeq) steroid 17-alpha-hydroxylase/17,20 lyase
KO
K00512
steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:
1.14.14.19
1.14.14.32
]
Organism
pbrv Petaurus breviceps papuanus (sugar glider)
Pathway
pbrv00140
Steroid hormone biosynthesis
pbrv01100
Metabolic pathways
pbrv04913
Ovarian steroidogenesis
pbrv04917
Prolactin signaling pathway
pbrv04927
Cortisol synthesis and secretion
pbrv04934
Cushing syndrome
Module
pbrv_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
pbrv_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
pbrv_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
pbrv_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pbrv00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
138169419 (CYP17A1)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
138169419 (CYP17A1)
04917 Prolactin signaling pathway
138169419 (CYP17A1)
04927 Cortisol synthesis and secretion
138169419 (CYP17A1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
138169419 (CYP17A1)
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:
pbrv00199
]
138169419 (CYP17A1)
Enzymes [BR:
pbrv01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.19 steroid 17alpha-monooxygenase
138169419 (CYP17A1)
1.14.14.32 17alpha-hydroxyprogesterone deacetylase
138169419 (CYP17A1)
Cytochrome P450 [BR:
pbrv00199
]
Cytochrome P450, animal type
CYP17 family
138169419 (CYP17A1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
p450
DUF7527
DUF5544
Motif
Other DBs
NCBI-GeneID:
138169419
NCBI-ProteinID:
XP_068954955
LinkDB
All DBs
Position
Unknown
AA seq
514 aa
AA seq
DB search
MWWFLIISLLTLLYYIWQKLGNLGKKYPMCLPHLPIVGSLPYMSVQDEAHIYFTKLKEKY
GHIYALWMGPSYVVVVNQFSLAKDMLLKKGKDFASRPQMVTTDILSGSGKGIAFSDYGPQ
WRMYRKLVQSTFSLFRDRSSQNFEKIICQEANTLCKRLANTEGQSVDPSKDCFLASANVI
CQFCFSNSWKQNDKDVEIIMNVSDAIIKALAKNNLVDIFPWIQLFPNKDLTLLKENVKSR
NELLEKKIKIEKEKFNKDSINNLLDTLLKAKMKTNSHLSQEQEVTDEHILMTLGDIFGAG
VETTSSVIKWILAYLLHYPEVKEKIQKEIDQKIGFTRTPLLSDRNQLLFLESTIREVLRI
RPVAPLLIPHVACTDSSIGEYTIPKGTRIYVNLWSIHHDPEEWDEPEQFNPERFLDKNKE
QLIMPTSSYFPFGGGPRVCVGEFLARAELFLFMAWVLQRFDLEVADNGELPSLEGVYGVV
YQINPFKMKFKLRKAWLSSVPGQQDPPPPAPEDS
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atgtggtggttcctcataatctccctgctgacccttctatactacatctggcagaagcta
gggaatttgggcaagaaatatcctatgtgtctgccccatctgcccatcgtggggagcctt
ccatatatgagcgtccaggatgaggcacacatctacttcaccaagcttaaggagaagtat
ggccacatctatgccctttggatgggtccttcctatgttgtagtagtgaaccagttctca
ctggccaaggacatgcttctcaagaagggcaaggattttgccagtcgcccccaaatggta
accacagacatcctgagtggctcaggcaaggggattgccttcagtgactatggtccccag
tggcgaatgtatcggaagctggtgcagtccaccttctccttgtttagggatcgctcctcc
cagaactttgaaaagatcatctgccaagaggccaatactctctgtaagaggctggccaac
acagaaggacagagcgtggacccaagtaaggactgttttctggcttctgccaatgtgatc
tgccagttctgcttcagcaactcctggaagcaaaatgataaggacgtagagatcataatg
aacgttagtgatgccatcatcaaagctctggccaagaacaacctggttgatatctttccc
tggattcagctgttccccaacaaagacctgacattgctgaaggagaacgtcaagtcacga
aacgagctactggagaaaaaaattaaaattgaaaaggagaaattcaacaaagattctatc
aacaacctcctggatacactgctgaaagccaagatgaaaaccaacagccatctgagccag
gagcaagaggtcacagatgagcacatcctgatgaccctgggtgacatctttggagctggg
gtggagacgaccagcagtgtcatcaagtggatccttgcctacctgctgcactatcctgag
gtaaaggagaagatccagaaggaaattgaccagaaaattggctttaccagaacacctctg
ctcagtgacaggaaccaacttctcttcctcgagtctacaatacgtgaagtactccgcata
cggccagtggctcccttgctcatcccccatgtggcatgtactgacagcagcattggagaa
tacaccatccccaaaggcaccaggatctatgtcaacctgtggtctatccatcatgaccct
gaagagtgggatgagccagagcagtttaatccggaacggttcctggacaagaataaggaa
cagcttatcatgccaacttccagctactttccctttggaggcggaccccgggtctgtgtt
ggggagttcttggcccgggcagagttattcctctttatggcctgggtcctacagagattt
gacctggaagtagctgataatggagaactaccctccttagagggggtatatggagtggtc
tatcagatcaatcccttcaaaatgaaattcaagcttcggaaggcctggcttagctcagtg
cctggccaacaagatcctcctccaccagctccggaagactcataa
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